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https://www.readbyqxmd.com/read/29327302/diffuse-idiopathic-skeletal-hyperostosis-is-associated-with-lumbar-spinal-stenosis-requiring-surgery
#1
Kentaro Yamada, Shigenobu Satoh, Hiroshi Hashizume, Noriko Yoshimura, Ryohei Kagotani, Yuyu Ishimoto, Yuichiro Abe, Hiromitsu Toyoda, Hidetomi Terai, Takeshi Masuda, Shigeyuki Muraki, Hiroaki Nakamura, Munehito Yoshida
Factors related to the onset and progression of lumbar spinal stenosis (LSS) have not yet been identified. Diffuse idiopathic skeletal hyperostosis (DISH) increases mechanical loading on the non-fused lumbar levels and may therefore lead to LSS. This cross-sectional study aimed to identify associations between LSS and DISH. This study included 2363 consecutive patients undergoing surgery for LSS and 787 general inhabitants without symptoms of LSS as participants of the population-based cohort study, Research on Osteoarthritis/Osteoporosis Against Disability...
January 11, 2018: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/29323824/a-case-of-atypical-synovitis-acne-pustulosis-hyperostosis-osteitis-sapho-syndrome-presenting-with-osteomyelitis-of-the-clavicle
#2
Chetan Sharma, Brian Chow
Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is considered after exclusion of infection and arthritis; however, microbial infection may be present in osteoarticular lesions of these patients. Chronic osteomyelitis and associated bacterial infection were detected in a recurrent osteoarticular lesion in an adolescent patient with a history of clavicle pain, who complained of recurrent swelling in the left clavicle. Most pediatric case reports of SAPHO syndrome describe patients with associated skin conditions...
June 2017: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29317363/spheno-orbital-meningiomas-surgery-multicenter-management-study-for-complex-extensive-tumors
#3
Louis-Marie Terrier, Florian Bernard, Henri-Dominique Fournier, Xavier Morandi, Stéphane Velut, Pierre-Louis Hénaux, Aymeric Amelot, Patrick François
BACKGROUND: Spheno-orbital meningiomas (SOMs) are complex tumors involving the sphenoid wing, the orbit, and sometimes the cavernous sinus with bone hyperostosis and sheet-like dural involvement. Optimal removal, proptosis cure and visual preservation remain a challenge. OBJECTIVE: To study the management of surgically treated SOMs METHODS: The clinical records of 130 consecutive patients undergoing surgery for SOMs were retrospectively collected in a database during a 20-year period to analyze symptoms, surgical technique, clinical outcome, and follow-up...
January 6, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29310888/secondary-hyperparathyroidism-causing-increased-jaw-bone-density-and-mandibular-pain-a-case-report
#4
Thomas Aerden, Koenraad Grisar, Margaux Nys, Constantinus Politis
We present the case of a 32-year-old male patient complaining of recurrent mandibular pain for 3.5 years. Panoramic radiography indicated increased cortical density of the mandibular lower border. Scintigraphy and single-photon emission computed tomography revealed metabolic hyperactivity in that region without pathologic lymph nodes. A bone biopsy specimen of the mandibular lower border did not have inflammation or cytologic atypia. Endocrinologic investigation confirmed secondary hyperparathyroidism as a result of hypovitaminosis D...
December 7, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29276872/successful-treatment-of-a-childhood-synovitis-acne-pustulosis-hyperostosis-and-osteitis-sapho-syndrome-with-subcutaneous-methotrexate-a-case-report
#5
Meltem Akçaboy, Sevcan Azime Bakkaloğlu-Ezgü, Bahar Büyükkaragöz, Emel Isıyel, Yasar Kandur, Enver Hasanoğlu, Necla Buyan
Akçaboy M, Bakkaloğlu-Ezgü SA, Büyükkaragöz B, Isıyel E, Kandur Y, Hasanoğlu E, Buyan N. Successful treatment of a childhood synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome with subcutaneous methotrexate: A case report. Turk J Pediatr 2017; 59: 184-188. SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) is defined as a syndrome that is related to various osteoarticular manifestations and chronic dermatological conditions especially severe acne. SAPHO syndrome is a rare and unusual clinical entity in childhood and treatment choices are variable...
2017: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/29204490/lumbar-chance-fracture-after-direct-anterior-total-hip-arthroplasty
#6
Michael Pitta, Corey J Wallach, Colleen Bauk, William G Hamilton
This report describes a patient with ankylosing spondylitis (AS) who underwent total hip arthroplasty (THA) by the direct anterior approach and sustained a L4-5 extension fracture dislocation with neural deficits. A magnetic resonance imaging revealed an epidural hematoma at the site of the fracture causing critical stenosis. The patient was taken to the operating room for a L3-S1 posterior decompression with L2-pelvis posterior spinal fusion. AS and diffuse idiopathic skeletal hyperostosis create a stiff spine that predisposes to fractures because of the larger moment arms experienced than normal spines...
December 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/29202732/sex-differences-in-response-to-targeted-kyphosis-specific-exercise-and-posture-training-in-community-dwelling-older-adults-a-randomized-controlled-trial
#7
Wendy B Katzman, Neeta Parimi, Amy Gladin, Eduard A Poltavskiy, Anne L Schafer, Roger K Long, Bo Fan, Shirley S Wong, Nancy E Lane
BACKGROUND: Hyperkyphosis, an excessive anterior curvature in the thoracic spine, is associated with reduced health status in older adults. Hyperkyphosis is highly prevalent, more common in older women than men. There is no standard intervention to reduce age-related hyperkyphosis. Sex differences in response to a kyphosis-specific exercise intervention are not known. METHODS: We conducted a randomized controlled trial of a targeted kyphosis-specific exercise and postural training program on the primary outcome Cobb angle of kyphosis, and investigated whether the magnitude of change differed between men and women...
December 4, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29198397/trends-in-mortality-and-biological-stress-in-a-medieval-polish-urban-population
#8
Tracy K Betsinger, Sharon DeWitte
Urbanization in pre-modern populations may have had a variety of consequences related to population crowding. However, research on the effects of urbanization have provided inconsistent results regarding the biological impact of this transition on human populations. The purpose of this study is to test the hypothesis that urbanization caused an increase in overall biological stress in a medieval (10th-13th centuries AD) Polish population. A human skeletal sample (n=164) was examined for the presence of porotic hyperostosis, cribra orbitalia, linear enamel hypoplasia, periosteal reaction, and specific infectious diseases...
December 2017: International Journal of Paleopathology
https://www.readbyqxmd.com/read/29191346/neutrophilic-dermatoses-kids-are-not-just-little-people
#9
Grace L Lee, Amy Y-Y Chen
Neutrophilic dermatoses are a group of inflammatory skin disorders characterized by an overactive innate immune system with dysregulation of neutrophils without underlying infectious etiology. The major representative conditions discussed are Sweet syndrome; pyoderma gangrenosum; neutrophilic eccrine hidradenitis; palmoplantar eccrine hidradenitis; subcorneal pustular dermatoses; bowel-associated dermatosis arthritis syndrome; and synovitis, acne, pustulosis, hyperostosis, and osteitis. We will also discuss other neutrophilic conditions present almost exclusively in the pediatric population, including congenital erosive and vesicular dermatosis with reticulated supple scarring and the recently described group of autoinflammatory diseases...
November 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/29185278/styloid-process-elongation-on-cervical-spine-computed-tomography-is-associated-with-the-enthesopathy-related-diseases-of-ankylosing-spondylitis-and-diffuse-idiopathic-skeletal-hyperostosis
#10
Talia Levy, Salim Bader, Kay-Geert Hermann, Gal Yaniv, Gahl Grinberg, Oshry Mozes, Merav Lidar, Iris Eshed
BACKGROUND: Enthesopathy may lead to calcification of the stylohyoid ligament and can cause elongation of the styloid process (SP). OBJECTIVES: To evaluate whether SP elongation is associated with two common enthesitis-related diseases: ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH). METHODS: Cervical spine computed tomography (CT) examinations of patients with DISH (n=64, Resnick criteria), AS (n=24, New York criteria) and a controls (no radiological signs of DISH or AS, n=54) were retrospectively evaluated...
November 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29185277/mri-findings-of-the-sacroiliac-joints-in-patients-with-low-back-pain-alternative-diagnosis-to-inflammatory-sacroiliitis
#11
Iris Eshed, Merav Lidar
BACKGROUND: Magnetic resonance imaging (MRI) is the most sensitive imaging modality for the detection of sacroiliitis. Diagnosing sacroiliitis on MRI is not always straightforward and can be challenging in some cases. OBJECTIVES: To evaluate the prevalence of alternative diagnoses suggested by MRI and characterize the MR appearance of the most common ones. METHODS: Consecutive MRI examinations of the sacroiliac joints (SIJ) performed between 2005 and 2012 were retrospectively evaluated for the presence of structural and active sacroiliitis findings according to the Assessment of SpondyloArthritis International Society guidelines...
November 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29184006/pain-improvement-in-camurati-engelmann-disease-after-anti-tnf%C3%AE-therapy
#12
Sónia Moreira, Bernardo Cunha, Nelson Pedro Jesus, Lèlita Santos
Camurati-Engelmann disease (CED) is a rare disorder included in the group of craniotubular hyperostosis diseases. Corticosteroids are used for pain management in CED, but in refractory or corticosteroid-non-tolerant patients, pain management is limited. We report the case of a woman with CED diagnosed in early infancy whose initial complaints included persistent bone pain associated with progressive functional disability. She was treated with steroids but over time became dependent on higher doses with only mild pain relief...
November 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29177083/correction-diffuse-idiopathic-skeletal-hyperostosis-dish-where-we-are-now-and-where-to-go-next
#13
(no author information available yet)
[This corrects the article DOI: 10.1136/rmdopen-2017-000472.][This corrects the article DOI: 10.1136/rmdopen-2017-000472.].
2017: RMD Open
https://www.readbyqxmd.com/read/29155874/morphological-characteristics-of-diffuse-idiopathic-skeletal-hyperostosis-in-the-cervical-spine
#14
Jessica T Bakker, Jonneke S Kuperus, Hugo J Kuijf, F Cumhur Oner, Pim A de Jong, Jorrit-Jan Verlaan
OBJECTIVES: Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by anterior ossification of the spine and can lead to dysphagia and airway obstruction. The morphology of the newly formed bone in the cervical spine is different compared to the thoracic spine, possibly due to dissimilarities in local vascular anatomy. In this study the spatial relationship of the new bone with the arterial system, trachea and esophagus was analyzed and compared between subjects with and without DISH...
2017: PloS One
https://www.readbyqxmd.com/read/29151015/diffuse-idiopathic-skeletal-hyperostosis-dish-as-a-cause-of-failure-following-distal-clavicle-excision-a-case-report-and-review-of-the-literature
#15
John Begly, Vineet Tyagi, Eric Strauss
Diffuse idiopathic skeletal hyperostosis (DISH) is common spinal condition characterized by increased calcification and ossification of ligaments and entheses, typically in the anterior aspect of the spine. However, extraspinal manifestations of the disease can occur and depending on the degree and location of involvement, may become symptomatic. We present the case of a 63-year-old male with a history of DISH, who failed initial open distal clavicle excision due to the postoperative development of heterotopic bone bridging across the acromioclavicular joint...
December 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/29142783/birth-order-and-maternal-age-for-reported-cases-of-severe-prenatal-cortical-hyperostosis-caffey-silverman-disease
#16
Rolf R Engel, Raul F Cifuentes
The spectrum of prenatal cortical hyperostosis includes a mild phenotype that typically presents after 35 weeks of gestation, and a severe form that presents earlier. The skeletal and systemic manifestations of the severe phenotype remain unexplained. A review of reported cases indicates that older mothers and firstborn infants are overrepresented. This combination suggests decreased fertility. Fourteen years after the birth of the present case, his mother presented with renal failure from multiple myeloma raising the possibility that a maternal antibody may play a role in the etiology of severe prenatal Caffey disease...
July 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/29124297/complete-resolution-and-remodeling-of-chronic-recurrent-multifocal-osteomyelitis-on-mri-and-radiographs
#17
Y J Berkowitz, S J Greenwood, G Cribb, K Davies, V N Cassar-Pullicino
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare condition thought to be under-diagnosed, with a true prevalence of more than the 1 in 10,000 estimated. It is a condition that is classically described as polyostotic with a relapsing and remitting course, preferentially affecting the metaphyses of tubular bones in the pediatric population. Lesions have characteristic appearances of cortical hyperostosis and mixed lytic/sclerotic medullary appearances radiographically, with active osteitis and periostitis best seen with fluid-sensitive sequences on magnetic resonance imaging (MRI)...
November 9, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29122103/skeletal-hyperostosis-as-a-cause-of-aspiration
#18
Christof Keller, Jürgen Knuth
No abstract text is available yet for this article.
October 20, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29104755/combined-approach-for-finding-susceptibility-genes-in-dish-chondrocalcinosis-families-whole-genome-wide-linkage-and-ibs-ibd-studies
#19
Ana Rita Couto, Bruna Parreira, Russell Thomson, Marta Soares, Deborah M Power, Jim Stankovich, Jácome Bruges Armas, Matthew A Brown
Twelve families with exuberant and early-onset calcium pyrophosphate dehydrate chondrocalcinosis (CC) and diffuse idiopathic skeletal hyperostosis (DISH), hereafter designated DISH/CC, were identified in Terceira Island, the Azores, Portugal. Ninety-two (92) individuals from these families were selected for whole-genome-wide linkage analysis. An identity-by-descent (IBD) analysis was performed in 10 individuals from 5 of the investigated pedigrees. The chromosome area with the maximal logarithm of the odds score (1...
2017: Human Genome Variation
https://www.readbyqxmd.com/read/29093022/giantin-knockout-models-reveal-a-feedback-loop-between-golgi-function-and-glycosyltransferase-expression
#20
Nicola L Stevenson, Dylan J M Bergen, Roderick E H Skinner, Erika Kague, Elizabeth Martin-Silverstone, Kate A Robson Brown, Chrissy L Hammond, David J Stephens
The Golgi is the cellular hub for complex glycosylation, controlling accurate processing of complex proteoglycans, receptors, ligands and glycolipids. Its structure and organisation are dependent on golgins, which tether cisternal membranes and incoming transport vesicles. Here, we show that knockout of the largest golgin, giantin, leads to substantial changes in gene expression but only limited effects on Golgi structure. Notably, 22 Golgi-resident glycosyltransferases, but not glycan-processing enzymes or the ER glycosylation machinery, are differentially expressed following giantin ablation...
December 15, 2017: Journal of Cell Science
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