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https://www.readbyqxmd.com/read/28431756/plexiform-fibromyxoma-a-rare-mesenchymal-gastric-tumor
#1
Pedro Luis Gonzalez-Cordero, Daniel Vara-Brenes, María Del Carmen Pecero-Hormigo, Jose María Mateos-Rodríguez, Javier Molina-Infante, Yvana Anavy Martínez Mateo, Miguel Fernández-Bermejo
No abstract text is available yet for this article.
April 18, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/28427840/aav-id-a-rapid-and-robust-assay-for-batch-to-batch-consistency-evaluation-of-aav-preparations
#2
Simon Pacouret, Mohammed Bouzelha, Rajani Shelke, Eva Andres-Mateos, Ru Xiao, Anna Maurer, Mathieu Mevel, Heikki Turunen, Trisha Barungi, Magalie Penaud-Budloo, Frédéric Broucque, Véronique Blouin, Philippe Moullier, Eduard Ayuso, Luk H Vandenberghe
Adeno-associated virus (AAV) vectors are promising clinical candidates for therapeutic gene transfer, and a number of AAV-based drugs may emerge on the market over the coming years. To insure the consistency in efficacy and safety of any drug vial that reaches the patient, regulatory agencies require extensive characterization of the final product. Identity is a key characteristic of a therapeutic product, as it ensures its proper labeling and batch-to-batch consistency. Currently, there is no facile, fast, and robust characterization assay enabling to probe the identity of AAV products at the protein level...
April 17, 2017: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/28426791/correction-cctop-an-intuitive-flexible-and-reliable-crispr-cas9-target-prediction-tool
#3
Manuel Stemmer, Thomas Thumberger, Maria Del Sol Keyer, Joachim Wittbrodt, Juan L Mateo
[This corrects the article DOI: 10.1371/journal.pone.0124633.].
2017: PloS One
https://www.readbyqxmd.com/read/28424665/ca-similichlamydia-in-epitheliocystis-co-infection-of-gilthead-seabream-gills-unique-morphological-features-of-a-deep-branching-chlamydial-family
#4
Helena M B Seth-Smith, Pantelis Katharios, Nancy Dourala, José M Mateos, Alexander G J Fehr, Lisbeth Nufer, Maja Ruetten, Maricruz Guevara Soto, Lloyd Vaughan
The Planctomycetes-Verrucomicrobia-Chlamydiae (PVC) bacterial superphylum constitutes a broad range of organisms with an intriguing array of ultrastructural morphologies, including intracellular membranes and compartments and their corresponding complex genomes encoding these forms. The phylum Chlamydiae are all obligate intracellular bacteria and, although much is already known of their genomes from various families and how these regulate the various morphological forms, we know remarkably little about what is likely the deepest rooting clade of this phylum, which has only been found to contain pathogens of marine and fresh water vertebrates...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28423612/correction-nebivolol-a-%C3%AE-1-adrenergic-blocker-protects-from-peritoneal-membrane-damage-induced-during-peritoneal-dialysis
#5
Georgios Liappas, Guadalupe González-Mateo, Anna Rita Aguirre, Hugo Abensur, Patricia Albar-Vizcaino, Emilio González Parra, Pilar Sandoval, Laura García Ramírez, Gloria Del Peso, Juan Manuel Acedo, María A Bajo, Rafael Selgas, José A Sánchez Tomero, Manuel López-Cabrera, Abelardo Aguilera
No abstract text is available yet for this article.
April 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423486/tick-host-conflict-immunoglobulin-e-antibodies-to-tick-proteins-in-patients-with-anaphylaxis-to-tick-bite
#6
Lourdes Mateos-Hernández, Margarita Villar, Angel Moral, Carmen García Rodríguez, Teresa Alfaya Arias, Verónica de la Osa, Francisco Feo Brito, Isabel G Fernández de Mera, Pilar Alberdi, Francisco Ruiz-Fons, Alejandro Cabezas-Cruz, Agustín Estrada-Peña, José de la Fuente
Tick-borne infectious diseases and allergies are a growing problem worldwide. Tick bite allergy has been associated with the direct effect of immunoglobulin E (IgE) response to tick salivary antigens, or secondary to the induction of allergy to red meat consumption through IgE antibodies against the carbohydrate α-Gal (Gal α 1-3Gal β 1-(3)4GlcNAc-R). However, despite the growing burden of this pathology, the proteins associated with anaphylaxis to tick bite have not been characterized. To address this question, a comparative proteomics approach was used to characterize tick proteins producing an IgE antibody response in a healthy individual with record of tick bites, which had not resulted in any allergic reactions, and two patients with anaphylactic reactions to Rhipicephalus bursa or Hyalomma marginatum tick bites...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28422398/do-mhealth-interventions-prevent-excessive-gestational-weight-gain
#7
S J Herring
Mobile technologies are nearly ubiquitous worldwide (Pew Research Center, Technology Device Ownership: 2015). These digital platforms hold considerable promise for delivering weight control interventions due to their broach reach, immediate scalability, and low implementation costs (Bennett G et al. Annu Rev Public Health 2009;30:273-92). There is evidence for their efficacy in promoting weight loss among non-pregnant adults with obesity (Flores Mateo G et al. J Med Internet Res 2015;17(11):e253), yet few studies have examined the feasibility and efficacy of mobile technologies for preventing excessive weight gain in pregnant women at highest risk...
April 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28420429/deptor-maintains-plasma-cell-differentiation-and-favorably-affects-prognosis-in-multiple-myeloma
#8
Dalia Quwaider, Luis A Corchete, Irena Misiewicz-Krzeminska, María E Sarasquete, José J Pérez, Patryk Krzeminski, Noemí Puig, María Victoria Mateos, Ramón García-Sanz, Ana B Herrero, Norma C Gutiérrez
BACKGROUND: The B cell maturation process involves multiple steps, which are controlled by relevant pathways and transcription factors. The understanding of the final stages of plasma cell (PC) differentiation could provide new insights for therapeutic strategies in multiple myeloma (MM). Here, we explore the role of DEPTOR, an mTOR inhibitor, in the terminal differentiation of myeloma cells, and its potential impact on patient survival. METHODS: The expression level of DEPTOR in MM cell lines and B cell populations was measured by real-time RT-PCR, and/or Western blot analysis...
April 18, 2017: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/28419178/acquiring-evidence-for-precision-prostate-cancer-care
#9
Joaquin Mateo, Suzanne Carreira, Johann S de Bono
No abstract text is available yet for this article.
April 13, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28416884/determination-of-soluble-dietary-fibre-content-of-okara-treated-with-high-hydrostatic-pressure-and-enzymes-a-comparative-evaluation-of-two-methods-aoac-and-hplc-elsd
#10
E Pérez-López, I Mateos-Aparicio, P Rupérez
ABSTRACT: Okara is a promising by-product from soybean and a rich source of dietary fibre, chiefly insoluble (IDF). To increase its solubility and functionality, a treatment with high hydrostatic pressure (HHP) assisted by food grade enzymes -Ultraflo(®) L or Viscozyme(®) L- has been performed. To monitor the effectiveness, an analysis of dietary fibre, mainly the soluble fraction (SDF), was accomplished by the AOAC enzymatic-gravimetric method with dialysis followed by both, spectrophotometric methods and High Performance Liquid Chromatography with Evaporative Light Scattering Detector (HPLC-ELSD) analysis of the soluble fraction...
April 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28416364/-implementation-of-nurse-demand-managment-in-primary-health-care-service-providers-in-catalonia
#11
Alba Brugués Brugués, Irene Cubells Asensio, Gemma Flores Mateo
OBJECTIVE: To describe and analyse the implementaction of nurse demand managment (NDM) among health care providers in Catalonia from 2005 to 2014. DESIGN: Cross sectional survey. Participants All service providers in Catalonia (n=37). Main measurements Interviews with nurse manager of each health care provides about ht barriers and facilitators concerning NDM. Facilitators and barriers were classified into 3 types: (i)health professional (competence, attitudes, motivation for change and individual characteristics); (ii)social context (patients and companions), and (iii)system related factors (organization and structure, economic incentives)...
April 14, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28415520/tuneable-hydrolytic-degradation-of-poly-l-lactide-scaffolds-triggered-by-zno-nanoparticles
#12
Erlantz Lizundia, Paula Mateos, José Luis Vilas
In this work we fabricate porous PLLA and PLLA/ZnO scaffolds with porosities ranging from 10 to 90% and average pore diameter of 125-250μm by solvent casting/particulate leaching method. The structural evolution of PLLA/ZnO scaffolds during their in vitro degradation in phosphate buffered saline (PBS) at physiological pH (7.4) has been studied as a function of porosity and obtained results were compared to plain PLLA scaffolds. The changes induced upon the hydrolytic degradation of scaffolds have been explored by measuring the pH changes of the medium, the mass loss, thermal transitions, crystalline structure, thermal stability and the morphological changes...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28412604/highlighting-the-differential-role-of-leaf-paraheliotropism-in-two-mediterranean-cistus-species-under-drought-stress-and-well-watered-conditions
#13
Giacomo Puglielli, Susana Redondo-Gómez, Loretta Gratani, Enrique Mateos-Naranjo
The differential degree by which paraheliotropism may counterbalance the deleterious impact of high irradiance between congeneric species in relation to different water availabilities has been poorly investigated. We followed the evolution of gas exchange, quenching analysis and OJIP parameters in restrained (R) and free (F) to move leaves of Cistus monspeliensis (CM) and Cistus salvifolius (CS) under drought stress (WS) and well-watered conditions (WW). Concerning gas exchange parameters, leaf restriction effect was overall not significant in CM except in apparent carboxylation efficiency (Ce) under WS, while CS showed a significant sensitivity of maximum net photosynthetic rate (Amax), stomatal conductance (gs) and Ce even under WW...
March 25, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28404450/does-lying-in-the-recovery-position-increase-the-likelihood-of-not-delivering-cardiopulmonary-resuscitation
#14
Miguel Freire-Tellado, Rubén Navarro-Patón, Maria Del Pilar Pavón-Prieto, Marta Fernández-López, Javier Mateos-Lorenzo, Ivan López-Fórneas
BACKGROUND: Resuscitation guidelines endorse unconscious and normally breathing out-of-hospital victims to be placed in the recovery position to secure airway patency, but recently a debate has been opened as to whether the recovery position threatens the cardiac arrest victim's safety assessment and delays the start of cardiopulmonary resuscitation. AIM: To compare the assessment of the victim's breathing arrest while placed in the recovery position versus maintaining an open airway with the continuous head tilt and chin lift technique to know whether the recovery position delays the cardiac arrest victim's assessment and the start of cardiopulmonary resuscitation...
April 9, 2017: Resuscitation
https://www.readbyqxmd.com/read/28401641/a-conserved-%C3%AE-proteobacterial-small-rna-contributes-to-osmoadaptation-and-symbiotic-efficiency-of-rhizobia-on-legume-roots
#15
Marta Robledo, Alexandra Peregrina, Vicenta Millán, Natalia I García-Tomsig, Omar Torres-Quesada, Pedro F Mateos, Anke Becker, José I Jiménez-Zurdo
Small non-coding RNAs (sRNAs) are expected to have pivotal roles in the adaptive responses underlying symbiosis of nitrogen-fixing rhizobia with legumes. Here, we provide primary insights into the function and activity mechanism of the Sinorhizobium meliloti trans-sRNA NfeR1 (Nodule Formation Efficiency RNA). Northern blot probing and transcription tracking with fluorescent promoter-reporter fusions unveiled high nfeR1 expression in response to salt stress and throughout the symbiotic interaction. The strength and differential regulation of nfeR1 transcription are conferred by a motif, which is conserved in nfeR1 promoter regions in α-proteobacteria...
April 12, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28400911/characterization-of-no-induced-nitrosative-status-in-human-placenta-from-pregnant-women-with-gestational-diabetes-mellitus
#16
Francisco Visiedo, Celeste Santos-Rosendo, Rosa M Mateos-Bernal, M Del Mar Gil-Sánchez, Fernando Bugatto, Manuel Aguilar-Diosdado, Carmen Segundo, Cristina López-Tinoco
Dysregulation of NO production is implicated in pregnancy-related diseases, including gestational diabetes mellitus (GDM). The role of NO and its placental targets in GDM pregnancies has yet to be determined. S-Nitrosylation is the NO-derived posttranslational protein modification that can modulate biological functions by forming NO-derived complexes with longer half-life, termed S-nitrosothiol (SNO). Our aim was to examine the presence of endogenous S-nitrosylated proteins in cysteine residues in relation to antioxidant defense, apoptosis, and cellular signal transduction in placental tissue from control (n = 8) and GDM (n = 8) pregnancies...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28399270/detection-and-establishment-of-aedes-aegypti-and-aedes-albopictus-diptera-culicidae-mosquitoes-in-california-2011-2015
#17
Marco E Metzger, Melissa Hardstone Yoshimizu, Kerry A Padgett, Renjie Hu, Vicki L Kramer
In 2011, a thriving population of Aedes albopictus (Skuse), the Asian tiger mosquito, was discovered within three cities in Los Angeles County over an estimated 52-km2 urban area. Two years later in 2013, Aedes aegypti (L.), the yellow fever mosquito, was detected within several urban areas of Madera, Fresno, and San Mateo counties. State and local vector control agencies responded with an aggressive effort to eradicate or interrupt the spread of these two invasive mosquitoes; however, known populations continued to expand outward and new infestations were identified at an accelerated pace in central and southern California...
February 16, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28398616/gas-phase-photochemical-overall-h2-s-splitting-by-uv-light-irradiation
#18
Herme G Baldovi, Josep Albero, Belen Ferrer, Diego Mateo, Mercedes Alvaro, Hermenegildo García
Splitting of hydrogen sulfide is achieved to produce value-added chemicals. Upon irradiation at 254 nm in the gas phase and in the absence of catalysts or photocatalysts at near room temperature, H2 S splits into stoichiometric amounts of H2 and S with a quantum efficiency close to 50 %. No influence of the presence of CH4 and CO2 (typical components in natural gas and biogas in which H2 S is an unwanted component) on the efficiency of overall H2 S splitting was observed. A mechanism for the H2 and S formation is proposed...
April 11, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28397067/proteomic-analysis-after-status-epilepticus-identifies-uchl1-as-protective-against-hippocampal-injury
#19
James P Reynolds, Eva M Jimenez-Mateos, Li Cao, Fang Bian, Mariana Alves, Suzanne F Miller-Delaney, An Zhou, David C Henshall
Brief, non-harmful seizures (preconditioning) can temporarily protect the brain against prolonged, otherwise injurious seizures. Following focal-onset status epilepticus (SE) in preconditioned (tolerance) and sham-preconditioned (injury) mice, we screened for protein changes using a proteomic approach and identified several putative candidates of epileptic tolerance. Among SE-induced changes to both proteomic screens, proteins clustered in key regulatory pathways, including protein trafficking and cytoskeletal regulation...
April 10, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28390206/comparative-efficacy-of-a-soft-toothbrush-with-tapered-tip-bristles-to-an-ada-reference-toothbrush-on-gingival-abrasion-over-a-12-week-period
#20
John Gallob, Dolores M Petrone, Luis R Mateo, Patricia Chaknis, Boyce M Morrison, Foti Panagakos, Malcolm Williams
OBJECTIVES: Evaluation of the impact of a soft toothbrush with tapered-tip (Test Toothbrush) bristles and an ADA reference toothbrush (ADA Toothbrush) on gingival abrasion over a 12-week period. METHODS: This was a randomized, single-center, examiner-blind, two-cell, parallel clinical research study and used the Danser Gingival Abrasion Index to assess the level of gingival abrasion after a single brushing, as well as after six weeks and 12 weeks of twice-daily brushing...
June 2016: Journal of Clinical Dentistry
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