keyword
MENU ▼
Read by QxMD icon Read
search

White matter hypertensities

keyword
https://www.readbyqxmd.com/read/27904123/posterior-reversible-encephalopathy-syndrome-with-extensive-deep-white-matter-lesions-including-the-temporal-pole
#1
Junichiro Ohira, Nobuyuki Mori, Shunsuke Kajikawa, Takeshi Nakamura, Tetsuya Arisato, Makio Takahashi
Posterior reversible encephalopathy syndrome (PRES) typically affects the posterior subcortical white matter. We report the case of a 55-year-old man with atypical PRES, who had malignant hypertension and renal dysfunction. Magnetic resonance imaging of the brain revealed extensive vasogenic edema in the deep white matter including the temporal pole, as well as in the brainstem and cerebellum. Antihypertensive therapy and hemodialysis contributed to both clinical and radiological improvement. Involvement of the deep white matter including the temporal pole, which is rarely affected in an ischemic stroke, should be recognized as a potential sign of PRES...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27837396/prognostic-importance-of-ambulatory-blood-pressure-monitoring-in-resistant-hypertension-is-it-all-that-matters
#2
REVIEW
Claudia R L Cardoso, Gil F Salles
PURPOSE OF REVIEW: This article reviews the current knowledge on the prognostic importance of ambulatory blood pressure (BP) monitoring parameters in patients with apparent treatment-resistant hypertension. RECENT FINDINGS: Although mean 24-h ambulatory BPs have been consistently established as better cardiovascular risk predictors than clinic (office) BPs in several clinical settings, and ambulatory BP monitoring is generally indicated in patients with resistant hypertension; there were only five previous longitudinal prospective studies that specifically evaluated the prognostic importance of ambulatory BP monitoring parameters in resistant hypertensive patients...
December 2016: Current Hypertension Reports
https://www.readbyqxmd.com/read/27795711/reversible-posterior-leukoencephalopathy-syndrome-developing-after-restart-of-sunitinib-therapy-for-metastatic-renal-cell-carcinoma
#3
Shinji Fukui, Yuta Toyoshima, Takeshi Inoue, Yoriaki Kagebayashi, Shoji Samma
A 64-year-old Japanese man had started molecular-targeted therapy with sunitinib for lymph node metastasis 5 years after nephrectomy for left renal cell carcinoma (clear cell carcinoma, G2, pT2N0M0). He was transported to our emergency department because of generalized tonic-clonic seizure, vision loss, and impaired consciousness with acute hypertension after 8 cycles of treatment (2 years after the initiation of sunitinib therapy, including a drug withdrawal period for one year). MRI of the brain (FLAIR images) showed multiple high-intensity lesions in the white matter of the occipital and cerebellar lobes, dorsal brain stem, and left thalamus...
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27790395/white-matter-disease-in-midlife-is-heritable-related-to-hypertension-and-shares-some-genetic-influence-with-systolic-blood-pressure
#4
Christine Fennema-Notestine, Linda K McEvoy, Randy Notestine, Matthew S Panizzon, Wai-Ying Wendy Yau, Carol E Franz, Michael J Lyons, Lisa T Eyler, Michael C Neale, Hong Xian, Ruth E McKenzie, William S Kremen
White matter disease in the brain increases with age and cardiovascular disease, emerging in midlife, and these associations may be influenced by both genetic and environmental factors. We examined the frequency, distribution, and heritability of abnormal white matter and its association with hypertension in 395 middle-aged male twins (61.9 ± 2.6 years) from the Vietnam Era Twin Study of Aging, 67% of whom were hypertensive. A multi-channel segmentation approach estimated abnormal regions within the white matter...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27773590/variant-type-of-posterior-reversible-encephalopathy-syndrome-with-diffuse-cerebral-white-matter-and-brainstem-involvement-associated-with-intracranial-hemorrhage
#5
Yin-Xi Zhang, Yang Zheng, Bi-Jun Zhang, Yun Zhang, Mei-Ping Ding, Bao-Rong Zhang
Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological syndrome characterized by reversible vasogenic edema typically at a posterior location of the cerebrum. PRES with prominent brainstem or basal ganglia involvement is defined as central-variant, which is rare. We herein report an atypical case of a 35-year-old man with a 2-year history of untreated hypertension who complained of recurrent dizziness. The patient presented with brainstem and diffuse white matter involvement associated with intracranial hemorrhage and recovered fully after therapy...
October 20, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27753892/os-01-01-association-of-lp-pla2-mass-and-aysmptomatic-intracranial-and-extracranial-arterial-stenosis-in-hypertension-patients
#6
Yan Wang, Jin Zhang, Yuesheng Qian, Xiaofeng Tang, Huawei Ling, Kemin Chen, Pingjin Gao, Dingliang Zhu
OBJECTIVE: Intracranial arterial stenosis (ICAS) is a common cause of ischemic stroke in Asians, whereas whites tend to have more extracranial lesions. Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been associated with ischemic stroke by a large amount of work. However, there are few studies focusing on the relationship of Lp-PLA2 and asymptomatic ICAS or extracranial arterial stenosis (ECAS). We hereby sought to explore the relationship of Lp-PLA2 and ICAS, ECAS and concurrent stenosis in stroke-free hypertensive patients in Chinese population...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753809/ssa-03-4-the-brain-screening-in-patients-with-hypertension
#7
Yuda Turana
Observational studies have conveyed the connection between hypertension and cognitive impairment. Several forms of dementia are more frequent in hypertensive subjects or those with previous history of hypertension compared to subjects with normal blood pressure.In many studies, hypertension occuring in mid-life is a risk factor of dementia occuring in later age. Long-standing hypertension will induce structural damages in the brain. It is also widely known that hypertension attributes to small vessel diseases causing lacunar infarcts and white matter lesions associated with cognitive decline...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27730376/cognitive-decline-in-metabolic-syndrome-is-linked-to-microstructural-white-matter-abnormalities
#8
Freddy J Alfaro, Vasileios-Arsenios Lioutas, Daniela A Pimentel, Chen-Chih Chung, Francisco Bedoya, Woo-Kyoung Yoo, Vera Novak
Subjects with metabolic syndrome (MetS) often show worse cognitive performance compared with the healthy population. We investigated whether microstructural white matter abnormalities are associated with cognitive performance in adults with MetS using diffusion tensor MR imaging. A total of 32 subjects with MetS (age 64.8 ± 7.8, 56.25 % female) and 23 age-, gender-, and education-matched healthy controls completed a battery of neuropsychological tests and diffusion tensor imaging (DTI) at 3-T MRI. Brain global and regional volumes, white matter fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD), and axial diffusivity (LD) were calculated...
December 2016: Journal of Neurology
https://www.readbyqxmd.com/read/27729576/association-between-endogenous-testosterone-and-cerebrovascular-disease-in-the-aric-study-atherosclerosis-risk-in-communities
#9
Reshmi Srinath, Rebecca F Gottesman, Sherita Hill Golden, Kathryn A Carson, Adrian Dobs
BACKGROUND AND PURPOSE: Epidemiological studies in men suggest a relationship between endogenous testosterone and ischemic vascular events. We hypothesized that low testosterone is independently associated with ischemic stroke and ischemic brain changes. METHODS: In 1558 male participants (mean [SD] age, 63.1 [5.6] years; body mass index, 28.2 [4.3] kg/m(2)) from visit 4 (1996-1998) of the ARIC study (Atherosclerosis Risk in Communities) without cardiovascular disease, stroke, and previous testosterone therapy, we measured plasma total testosterone by liquid chromatography mass spectrometry using morning samples and divided levels into tertiles (median [25th-75th percentile], 377...
November 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27727072/association-between-serum-cystatin-c-level-and-total-magnetic-resonance-imaging-burden-of-cerebral-small-vessel-disease-in-patients-with-acute-lacunar-stroke
#10
Song Yang, Jing Cai, Rulan Lu, Jian Wu, Min Zhang, Xianju Zhou
OBJECTIVE: Chronic kidney disease (CKD) is associated with cerebral small vessel disease (cSVD). However, the relationship between serum cystatin C (CysC) level, a highly sensitive marker of impaired kidney function, and cSVD has not been fully understood. This study aimed to investigate the association between serum CysC level and total burden of cSVD on magnetic resonance imaging (MRI) in patients with acute lacunar stroke. MATERIALS AND METHODS: A total of 210 patients with first-ever acute lacunar stroke occurring within 1 week after onset were included in this study...
October 7, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27716145/kidney-function-is-associated-with-severity-of-white-matter-hyperintensity-in-patients-with-acute-ischemic-stroke-tia
#11
Lixia Zong, Ming Yao, Jun Ni, Lixin Zhou, Jing Yuan, Bin Peng, Yi-Cheng Zhu, Liying Cui
BACKGROUND: Previous studies suggested the potential interactions between cerebrovascular diseases and impaired renal function. However, the relationship between renal function and white matter hyperintensity (WMH), marker of cerebral small vessel disease, in patients with acute ischemic stroke (AIS) or transient ischemic attack (TIA) remains unknown. METHODS: We consecutively enrolled 1632 subjects with AIS or TIA who underwent brain MRI for this analysis. The severity of WMH in both of periventricular (PVH) and deep subcortical white matter (SDWMH) was evaluated using Fazekas scale...
October 6, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27680506/influence-of-cerebral-white-matter-hyperintensities-on-cognitive-impairment-in-elderly-medical-patients
#12
Koichi Shibata, Yoshiko Nishimura, Kuniaki Otsuka, Hiroshi Sakura
AIM: We investigated the characteristics of elderly medical patients with white matter hyperintensities on magnetic resonance imaging. METHODS: A total of 213 patients (123 men and 90 women; mean age 74.8 years) reported their history of hypertension, diabetes, dyslipidemia, previous stroke, coronary heart disease and chronic kidney disease (CKD). All patients completed the Mini-Mental State Examination and Geriatric Depression Scale. White matter hyperintensities were evaluated for the periventricular region, basal ganglia (BGH), deep white matter and infratentorial region, and brain atrophy was calculated as bicaudate ratios...
September 29, 2016: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/27664989/cathepsin-a-related-arteriopathy-with-strokes-and-leukoencephalopathy-carasal
#13
Marianna Bugiani, Sietske H Kevelam, Hannah S Bakels, Quinten Waisfisz, Chantal Ceuterick-de Groote, Hans W M Niessen, Truus E M Abbink, Saskia A M J Lesnik Oberstein, Marjo S van der Knaap
OBJECTIVE: To characterize the clinical and MRI features of 2 families with adult-onset dominant leukoencephalopathy and strokes and identify the underlying genetic cause. METHODS: We applied MRI pattern recognition, whole-exome sequencing, and neuropathology. RESULTS: Based on brain imaging, 13 family members of 40 years or older from 2 families were diagnosed with the disease; in 11 family members of the same age, MRI was normal. In the affected family members, MRI showed a leukoencephalopathy that was disproportionately severe compared to the clinical disease...
October 25, 2016: Neurology
https://www.readbyqxmd.com/read/27662301/the-role-of-cerebrovascular-disease-on-cognitive-and-functional-status-and-psychosis-in-severe-alzheimer-s-disease
#14
Julia Kim, Tom A Schweizer, Corinne E Fischer, David G Munoz
BACKGROUND: The pathophysiology behind psychosis in patients with Alzheimer's disease (AD) remains unknown. Recently, vascular risk factors have been recognized as important modifiers of the clinical presentation of AD. OBJECTIVE: The purpose of our study is to investigate the mechanism through which vascular risk factors mediate psychosis and whether or not it involves cerebrovascular lesions. METHODS: Data was provided by the National Alzheimer's Coordinating Centre...
November 1, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27649085/white-matter-lesions-prevalence-and-clinical-phenotype-in-asymptomatic-individuals-aged-%C3%A2-50-years
#15
Jean-Philippe David, Emilie Ferrat, Juliette Parisot, Henri Naga, Samia Lakroun, Feriel Menasria, Sofiane Saddedine, Pierre-André Natella, Elena Paillaud, Isabelle Fromentin, Sylvie Bastuji-Garin
BACKGROUND: To assess the prevalence of early confluent/confluent white matter lesions (ec/cWMLs) in asymptomatic individuals aged ≥50 years and to identify associated clinical phenotypes. METHODS: Cross-sectional analysis of 141 asymptomatic individuals aged ≥50 years assessed at an outpatient department in France. Brain magnetic resonance imaging was rated using the Fazekas scale. Age-adjusted odds ratios (ORs) and 95% confidence intervals were estimated using logistic models to investigate factors associated with ec/cWMLs; independent risk factors were identified by multivariate analysis...
September 21, 2016: Dementia and Geriatric Cognitive Disorders
https://www.readbyqxmd.com/read/27643255/ssa-03-4-the-brain-screening-in-patients-with-hypertension
#16
Yuda Turana
Observational studies have conveyed the connection between hypertension and cognitive impairment. Several forms of dementia are more frequent in hypertensive subjects or those with previous history of hypertension compared to subjects with normal blood pressure.In many studies, hypertension occuring in mid-life is a risk factor of dementia occuring in later age. Long-standing hypertension will induce structural damages in the brain. It is also widely known that hypertension attributes to small vessel diseases causing lacunar infarcts and white matter lesions associated with cognitive decline...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27643238/os-01-01-association-of-lp-pla2-mass-and-aysmptomatic-intracranial-and-extracranial-arterial-stenosis-in-hypertension-patients
#17
Yan Wang, Jin Zhang, Yuesheng Qian, Xiaofeng Tang, Huawei Ling, Kemin Chen, Pingjin Gao, Dingliang Zhu
OBJECTIVE: Intracranial arterial stenosis (ICAS) is a common cause of ischemic stroke in Asians, whereas whites tend to have more extracranial lesions. Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been associated with ischemic stroke by a large amount of work. However, there are few studies focusing on the relationship of Lp-PLA2 and asymptomatic ICAS or extracranial arterial stenosis (ECAS). We hereby sought to explore the relationship of Lp-PLA2 and ICAS, ECAS and concurrent stenosis in stroke-free hypertensive patients in Chinese population...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27639120/cerebral-amyloid-is-associated-with-greater-white-matter-hyperintensity-accrual-in-cognitively-normal-older-adults
#18
Julia A Scott, Meredith N Braskie, Duygu Tosun, Pauline Maillard, Paul M Thompson, Michael Weiner, Charles DeCarli, Owen T Carmichael
Cross-sectional studies show that elevated cerebral amyloid is associated with greater white-matter hyperintensity (WMH) burden in cognitively normal (CN) older adults. However, the relative time courses of amyloid and WMH accrual are unclear. To address this, we tested the associations between known WMH correlates-age, hypertension, and amyloid-with WMH accrual rate. We used brain magnetic resonance imaging to measure WMH change in 112 CN Alzheimer's Disease Neuroimaging Initiative (GO/2) participants over a 2-year period...
August 24, 2016: Neurobiology of Aging
https://www.readbyqxmd.com/read/27637962/cerebrovascular-disease
#19
M L P Portegies, P J Koudstaal, M A Ikram
With 16.9 million people who suffered a first-ever stroke in 2010 worldwide, stroke is a very common vascular disease. Epidemiologic studies have played an essential role in assessing this burden and in detecting the risk factors for stroke. Primary prevention of these risk factors, primarily hypertension, smoking, diabetes, and atrial fibrillation, has reduced the incidence in high-income countries. However, stroke remains a major cause of death and disability, and therefore research should be continued. Subarachnoid hemorrhages are less prevalent than strokes but have an even higher risk of death...
2016: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/27630528/william-b-white-explains-the-changes-in-the-way-we-look-at-blood-pressure-which-numbers-matter-most-and-why-can-they-be-deceptive
#20
Jack McCain
Dr. White, known worldwide as an expert in the use of 24-hour ambulatory blood pressure monitoring (ABPM), discusses hypertension, the importance of accurate measurement, and the utility of ABPM for effective diagnoses and treatment.
September 2016: P & T: a Peer-reviewed Journal for Formulary Management
keyword
keyword
91059
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"