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https://www.readbyqxmd.com/read/28545145/respiratory-response-to-temperature-of-three-populations-of-aurelia-aurita-polyps-in-northern-europe
#1
Danja P Höhn, Cathy H Lucas, Sven Thatje
The benthic life stage (polyp or scyphistoma) of the bloom-forming jellyfish, Aurelia aurita (Linnaeus, 1759), also known as the moon jellyfish, contributes to the seasonal occurrence and abundance of medusa blooms via asexual reproduction. A. aurita is widely distributed in coastal areas in northern Europe, and one of the most studied jellyfish species. While the physiology of the visible medusa is largely understood, understanding of the physiology of the perennial benthic life-stage is scarce. To measure the physiological tolerance of A...
2017: PloS One
https://www.readbyqxmd.com/read/28544572/inositol-treatment-of-anovulation-in-women-with-polycystic-ovary-syndrome-a-meta-analysis-of-randomised-trials
#2
Jyotsna Pundir, Dimitrios Psaroudakis, Prakash Savnur, Priya Bhide, Luca Sabatini, Helena Teede, Arri Coomarasamy, Shakila Thangaratinam
BACKGROUND: Polycystic ovary syndrome is a common cause of anovulation and infertility, and a risk factor for development of metabolic syndrome and endometrial cancer. OBJECTIVES: Systematic review and meta-analysis of randomised controlled trials that evaluated the effects of inositol as an ovulation-induction agent. SEARCH STRATEGY: We searched MEDLINE, EMBASE, Cochrane and ISI conference proceedings, Register and Meta-register for RCTs and WHO trials' search portal...
May 24, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28543857/vena-cava-responsiveness-to-controlled-isovolumetric-respiratory-efforts
#3
Anna Folino, Marco Benzo, Paolo Pasquero, Andrea Laguzzi, Luca Mesin, Alessandro Messere, Massimo Porta, Silvestro Roatta
OBJECTIVES: Respirophasic variation of inferior vena cava (IVC) size is affected by large variability with spontaneous breathing. This study aims at characterizing the dependence of IVC size on controlled changes in intrathoracic pressure. METHODS: Ten healthy subjects, in supine position, performed controlled isovolumetric respiratory efforts at functional residual capacity, attaining positive (5, 10, and 15 mmHg) and negative (-5, -10, and -15 mmHg) alveolar pressure levels...
May 22, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28543610/metallic-nanoparticles-irradiated-by-low-energy-protons-for-radiation-therapy-are-there-significant-physical-effects-to-enhance-the-dose-delivery
#4
Anne-Catherine Heuskin, Bernard Gallez, Olivier Feron, Philippe Martinive, Carine Michiels, Stéphane Lucas
PURPOSE: To identify which physical properties of nanoparticles are correlated to the survival fraction of cells exposed in vitro to low energy protons in combination with nanoparticles. METHODS: The Geant4 simulation toolkit (version 10.3) was used to model nanoparticles of different sizes (5 to 50 nm) and materials (Ti, Zr, Hf, Ta, Au, Pt), with or without an organic capping ensuring biocompatibility and to irradiate them with 1.3 or 4 MeV protons and 5.3 MeV alpha particles...
May 23, 2017: Medical Physics
https://www.readbyqxmd.com/read/28543279/role-of-ampa-receptors-in-homocysteine-nmdar-induced-crosstalk-between-erk-and-p38-map-kinase
#5
Ranjana Poddar, Alexandria Chen, Lucas Winter, Sathyanarayanan Rajagopal, Surojit Paul
Homocysteine, a metabolite of the methionine cycle has been reported to play a role in neurotoxicity through activation of NMDAR-mediated signaling pathway. The proposed mechanisms associated with homocysteine-NMDAR induced neurotoxicity involve a unique signaling pathway that triggers a crosstalk between ERK and p38 MAPKs, where activation of p38 MAPK is downstream of and dependent on ERK MAPK. However, the molecular basis of the ERK MAPK mediated p38 MAPK activation is not understood. The current study investigates whether AMPARs play a role in facilitating the ERK MAPK mediated p38 MAPK activation...
May 24, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28541688/circularly-polarized-luminescence-of-silica-grafted-europium-chiral-derivatives-prepared-through-a-sequential-functionalization
#6
Lidia Armelao, Daniela Belli Dell'Amico, Luca Bellucci, Gregorio Bottaro, Lorenzo Di Bari, Luca Labella, Fabio Marchetti, Simona Samaritani, Francesco Zinna
We describe a new organic/inorganic material emitting circularly polarized luminescence (CPL). The hybrid system was obtained by the following steps: (i) preliminary grafting of the europium N,N-dibutylcarbamate [Eu(O2CNBu2)3] complex onto silica, (ii) substitution of the residual carbamato groups with anionic 1,3-diphenyl-1,3-propanedionato ligands (dbm), and (iii) subsequent introduction of the neutral tridentate chiral ligand 2,6-bis(isopropyl-2-oxazolin-2-yl)pyridine ((i)Pr-PyBox) in the metal coordination sphere...
May 25, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28541667/optically-multiresponsive-heteroleptic-platinum-dithiolene-complex-with-proton-switchable-properties
#7
Salahuddin Attar, Davide Espa, Flavia Artizzu, Luca Pilia, Angela Serpe, Maddalena Pizzotti, Gabriele Di Carlo, Luciano Marchiò, Paola Deplano
Both linear- and nonlinear-optical properties of Bu4N[Pt(L1)(L2)] (1; L1 = [4',5':5,6][1,4]dithiino[2,3-b]quinoxaline-1',3'dithiolato; L2 = (R)-α-MBAdto dithiooxamidate, where (R)-α-MBA = (R)-(+)-α-methylbenzyl) upon HCl addition at room temperature change dramatically: the color turns from deep blue to green; the luminescence switches from deep red to green; the nonlinear-optical response (first hyperpolarizability) increases by a factor of 12. Thus, 1 behaves as a unique multiresponsive optical switch whose properties can be followed by the naked eye...
May 25, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28540564/digital-breast-tomosynthesis-dbt-recommendations-from-the-italian-college-of-breast-radiologists-icbr-by-the-italian-society-of-medical-radiology-sirm-and-the-italian-group-for-mammography-screening-gisma
#8
Daniela Bernardi, Paolo Belli, Eva Benelli, Beniamino Brancato, Lauro Bucchi, Massimo Calabrese, Luca A Carbonaro, Francesca Caumo, Beatrice Cavallo-Marincola, Paola Clauser, Chiara Fedato, Alfonso Frigerio, Vania Galli, Livia Giordano, Paolo Giorgi Rossi, Paola Golinelli, Doralba Morrone, Giovanna Mariscotti, Laura Martincich, Stefania Montemezzi, Carlo Naldoni, Adriana Paduos, Pietro Panizza, Federica Pediconi, Fiammetta Querci, Antonio Rizzo, Gianni Saguatti, Alberto Tagliafico, Rubina M Trimboli, Marco Zappa, Chiara Zuiani, Francesco Sardanelli
This position paper, issued by ICBR/SIRM and GISMa, summarizes the evidence on DBT and provides recommendations for its use. In the screening setting, DBT in adjunct to digital mammography (DM) increased detection rate by 0.5-2.7‰ and decreased false positives by 0.8-3.6% compared to DM alone in observational and double-testing experimental studies. The reduction in recall rate could be less prominent in those screening programs which already have low recall rates with DM. The increase in radiation exposure associated with DM/DBT protocols has been solved by the introduction of synthetic mammograms (sDM) reconstructed from DBT datasets...
May 25, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28540114/expert-consensus-on-predictive-parameters-for-the-occurrence-of-a-fall-and-a-contralateral-hip-fracture-1-and-3-years-after-hip-fracture-a-delphi-survey
#9
Alexander Joeris, Anahí Hurtado-Chong, Michael Blauth, Joerg Goldhahn, Nicolas S Bodmer, Lucas M Bachmann
BACKGROUND: Early identification of people at risk for a contralateral hip fracture would be desirable to favorably influence patients' prognosis. A recent systematic review failed to depict stringent patterns of risk parameters to be used for decision-making in clinical practice. OBJECTIVE: To perform a consensus study using the Delphi method to reach an expert consensus on predictive parameters for the occurrence of a fall and a contralateral hip fracture 1 and 3 years after hip fracture...
June 2017: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/28538805/the-effect-of-epidurally-administered-dexamethasone-with-lignocaine-for-post-operative-analgesia-in-dogs-undergoing-ovariohysterectomy-a-dose-response-study
#10
Larissa Correa Hermeto, Rafael de Rossi, Natalia de Andrade Bicudo, Klebs Tavares Assis, Lucas Latta Escobar, Pedro Santana de Camargo
Purpose: To evaluate the postoperative analgesic and adverse effects of three doses of dexamethasone, administered epidurally in combination with lignocaine, in dogs undergoing ovariohysterectomy (OVH). Methods: Twenty-four female dogs undergoing ovariohysterectomy were pre-medicated with acepromazine and general anaesthesia was induced and maintained with propofol. Animals were randomly allocated into four groups of six. The control group was given lignocaine 2% (LI) and the treatment groups were given lignocaine with either 2 mg dexamethasone (LIDEX2), 4 mg dexamethasone (LIDEX4) or 8 mg dexamethasone (LIDEX8) administered at the lumbosacral epidural space...
April 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28538758/same-tt2r2-score-in-the-outpatient-anticoagulation-clinic-to-predict-time-in-therapeutic-range-and-adverse-events
#11
Fernando Pivatto, Rafael Selbach Scheffel, Lucas Ries, Ricardo Roitman Wolkind, Roberta Marobin, Sabrina Sigal Barkan, Luís Carlos Amon, Andréia Biolo
Background: The SAMe-TT2R2 score was developed to predict which patients on oral anticoagulation with vitamin K antagonists (VKAs) will reach an adequate time in therapeutic range (TTR) (> 65%-70%). Studies have reported a relationship between this score and the occurrence of adverse events. Objective: To describe the TTR according to the score, in addition to relating the score obtained with the occurrence of adverse events in patients with nonvalvular atrial fibrillation (AF) on oral anticoagulation with VKAs...
April 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28538325/heart-rate-variability-discriminates-competitive-levels-in-professional-soccer-players
#12
Riccardo Proietti, Selenia di Fronso, Lucas A Pereira, Laura Bortoli, Claudio Robazza, Fabio Y Nakamura, Maurizio Bertollo
Proietti, R, di Fronso, S, Pereira, LA, Bortoli, L, Robazza, C, Nakamura, FY, and Bertollo, M. Heart rate variability discriminates competitive levels in professional soccer players. J Strength Cond Res 31(6): 1719-1725, 2017-Heart rate variability (HRV) has been increasingly used to monitor team sports athletes. Besides the traditional time domain indices (i.e., the SD of successive RR intervals [SDNN] and the root mean square difference of successive normal RR intervals [RMSSD]), recently the use of the stress score (SS), which is an inverse function of the SD2 index derived from the Poincaré plot, and the sympathetic/parasympathetic ratio (S/PS) to monitor soccer players has been proposed...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28537847/diagnostic-performance-of-mri-versus-galactography-in-women-with-pathologic-nipple-discharge-a-systematic-review-and-meta-analysis
#13
Nicole Berger, Andrea Luparia, Giovanni Di Leo, Luca Alessandro Carbonaro, Rubina Manuela Trimboli, Federico Ambrogi, Francesco Sardanelli
OBJECTIVE: The objective of our study was to perform a systematic review of the literature of the diagnostic accuracy of MRI compared with galactography in women with pathologic nipple discharge. MATERIALS AND METHODS: A systematic literature search was performed (MEDLINE, Embase, Web of Science) for articles evaluating the diagnostic performance of MRI and galactography in patients with pathologic nipple discharge and with histologic verification or clinical follow-up...
May 24, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28537756/chemoembolization-adopting-polyethylene-glycol-drug-eluting-embolics-loaded-with-doxorubicin-for-the-treatment-of-hepatocellular-carcinoma
#14
Camillo Aliberti, Riccardo Carandina, Donatella Sarti, Luca Mulazzani, Enrico Pizzirani, Stefano Guadagni, Giammaria Fiorentini
OBJECTIVE: The purpose of this study is to determine the efficacy and tolerability of transarterial chemoembolization (TACE) using polyethylene glycol (PEG) drug-elutable microspheres loaded with doxorubicin for treatment of hepatocellular carcinoma (HCC). SUBJECTS AND METHODS: Forty-two patients with unresectable HCC, as determined by a tumor board, were assigned to undergo TACE and were treated with PEG drug-elutable embolics loaded with doxorubicin. Patients were prospectively enrolled and included 32 (76%) men and 10 (24%) women...
May 24, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28537389/silsesquioxane-terpyridine-nano-building-blocks-for-the-design-of-three-dimensional-polymeric-networks
#15
Esther Carbonell, Lucia A Bivona, Luca Fusaro, Carmela Aprile
Novel polyhedral oligomeric silsesquioxanes (POSS) decorated with eight terpyridine moieties were synthesized in a one-pot procedure via Heck coupling reaction with the aim of investigating the possible formation of three-dimensional extended supramolecular organizations. The monosubstituted analogue was also prepared and used as a model compound. Both POSS-based nanostructures were extensively characterized via (1)H, (13)C, and (29)Si nuclear magnetic resonance (NMR), ultraviolet-visible spectroscopies and combustion chemical analysis...
May 24, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28537040/accuracy-of-99mtc-hydroxymethylene-diphosphonate-scintigraphy-for-diagnosis-of-transthyretin-cardiac-amyloidosis
#16
Francesco Cappelli, Chiara Gallini, Carlo Di Mario, Egidio Natalino Costanzo, Luca Vaggelli, Francesca Tutino, Alfonso Ciaccio, Simone Bartolini, Paola Angelotti, Sabrina Frusconi, Silvia Farsetti, Giuseppe Vergaro, Assuero Giorgetti, Paolo Marzullo, Dario Genovesi, Michele Emdin, Federico Perfetto
BACKGROUND AND AIM: Either 99mTechnetium diphosphonate (Tc-DPD) or pyrophosphate (Tc-PYP) scintigraphy plays a relevant role in diagnosing transthyretin cardiac amyloidosis (CA), and labeled radiotracers have been extensively studied in diagnosing CA. Few studies have analyzed and validated 99mTc-Hydroxymethylene diphosphonate (Tc-HMDP). Our aim was to validate the diagnostic accuracy of Tc-HMDP total-body scintigraphy in a cohort of patients with biopsy-proven transthyretin CA. METHODS AND RESULTS: We retrospectively evaluated all patients undergoing 99mTc-HMDP total-body scintigraphy, in adjunct to a comprehensive diagnostic work-up for suspected CA...
May 23, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28536907/drug-use-in-older-adults-with-amyotrophic-lateral-sclerosis-near-the-end-of-life
#17
Giulia Grande, Lucas Morin, Davide Liborio Vetrano, Johan Fastbom, Kristina Johnell
BACKGROUND: Amyotrophic lateral sclerosis (ALS), with its certain prognosis and swift progression, raises concerns regarding the adequacy of pharmacological treatment, including the risk-benefit profiles of prescribed drugs. OBJECTIVE: Our objective was to evaluate the use of prescription drugs over the course of the last year of life in older adults with ALS. METHODS: We conducted a nationwide retrospective cohort study of older adults who died with ALS in Sweden between 2007 and 2013...
May 23, 2017: Drugs & Aging
https://www.readbyqxmd.com/read/28536806/increased-infiltration-of-natural-killer-and-t-cells-in-colorectal-liver-metastases-improves-patient-overall-survival
#18
Matteo Donadon, Kelly Hudspeth, Matteo Cimino, Luca Di Tommaso, Max Preti, Paolo Tentorio, Massimo Roncalli, Domenico Mavilio, Guido Torzilli
INTRODUCTION: Cancer heterogeneity and degree of intra-tumoral immune cells represent variables affecting overall survival (OS). The present study investigated the impact of natural killer (NK) and T cells infiltrating colorectal liver metastases (CLM) in patients undergoing hepatectomy after neoadjuvant chemotherapy. METHODS: The frequencies of intra-tumoral, marginal, and peritumoral CD3+ T and NKp46+ NK cells were determined for 121 patients. OS was assessed in relation to prognostic factors...
May 23, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28536552/the-effectiveness-of-a-new-school-based-media-literacy-intervention-on-adolescents-doping-attitudes-and-supplements-use
#19
Fabio Lucidi, Luca Mallia, Fabio Alivernini, Andrea Chirico, Sara Manganelli, Federica Galli, Valeria Biasi, Arnaldo Zelli
The aim of the study was to evaluate the effectiveness of a media literacy intervention targeting, for the first time, the specific topic of Performance and Appearance Enhancing Substances (PAESs) use in high-school students. Overall, 389 students (52% male) aged between 13 and 19 years (mean = 16.56 year; SD = 1.26) participated to a media literacy intervention (i.e., "intervention group") while 103 students aged between 14 and 19 year (mean = 16.10 year; SD = 1.38) were considered as the control group (i...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28536490/apparent-diffusion-coefficient-by-diffusion-weighted-magnetic-resonance-imaging-as-a-sole-biomarker-for-staging-and-prognosis-of-gastric-cancer
#20
Francesco Giganti, Alessandro Ambrosi, Damiano Chiari, Elena Orsenigo, Antonio Esposito, Elena Mazza, Luca Albarello, Carlo Staudacher, Alessandro Del Maschio, Francesco De Cobelli
OBJECTIVE: To investigate the role of apparent diffusion coefficient (ADC) from diffusion-weighted magnetic resonance imaging (DW-MRI) when applied to the 7th TNM classification in the staging and prognosis of gastric cancer (GC). METHODS: Between October 2009 and May 2014, a total of 89 patients with non-metastatic, biopsy proven GC underwent 1.5T DW-MRI, and then treated with radical surgery. Tumor ADC was measured retrospectively and compared with final histology following the 7th TNM staging (local invasion, nodal involvement and according to the different groups - stage I, II and III)...
April 2017: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
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