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https://www.readbyqxmd.com/read/28727996/efficacy-and-safety-of-one-stage-posterior-hemivertebral-resection-for-unbalanced-multiple-hemivertebrae-a-more-than-2-year-follow-up
#1
Yong Huang, Ganjun Feng, Yueming Song, Limin Liu, Chunguang Zhou, Lei Wang, Zhongjie Zhou, Xi Yang
OBJECTIVE: One-stage posterior hemivertebral resection has been proven to be an effective, reliable surgical option for treating congenital scoliosis due to a single hemivertebra. To date, however, no studies of treating unbalanced multiple hemivertebrae have appeared. This study evaluated the efficacy and safety of one-stage posterior hemivertebral resection for unbalanced multiple hemivertebrae. PATIENTS AND METHODS: Altogether, we studied 15 patients with unbalanced multiple hemivertebrae who had undergone hemivertebral resection using the one-stage posterior approach with at least 2 years of follow-up...
July 12, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28724196/a-local-agreement-pattern-measure-based-on-hazard-functions-for-survival-outcomes
#2
Tian Dai, Ying Guo, Limin Peng, Amita K Manatunga
Assessing agreement is often of interest in biomedical and clinical research when measurements are obtained on the same subjects by different raters or methods. Most classical agreement methods have been focused on global summary statistics, which cannot be used to describe various local agreement patterns. The objective of this work is to study the local agreement pattern between two continuous measurements subject to censoring. In this article, we propose a new agreement measure based on bivariate hazard functions to characterize the local agreement pattern between two correlated survival outcomes...
July 19, 2017: Biometrics
https://www.readbyqxmd.com/read/28723172/periodically-patterned-au-tio2-heterostructures-for-photoelectrochemical-sensor
#3
Limin Guo, Zhao Li, Kyle Marcus, Steven Navarro, Kun Liang, Le Zhou, Prabhu Doss Mani, Stephen J Florczyk, Kevin R Coffey, Nina Orlovskaya, Yong-Ho Sohn, Yang Yang
Periodically patterned Au nanorods in TiO2 nanocavities (Au NRs@TiO2) were fabricated via magnetron sputtering followed by a thermal dewetting process. This innovative Au NRs@TiO2 heterostructure was used as a plasmonic sensing platform for photoelectrochemical detection of glucose and lactose. This Au NRs@TiO2 patterned heterostructure possesses superior sensing properties to other Au nanoparticle-based sensors because (i) localized surface plasmon resonance (LSPR) generated at Au/TiO2 interfaces enhanced sensitivity of glucose (lactose) amperometric detection; (ii) periodic Au nanocrystals in TiO2 nanocavities accelerated charge separation and transfer rate, especially under monochromatic blue light irradiation; (iii) discrete planar architectures comprising Au NRs immobilized on TiO2 substrates significantly improved stability and reusability of the sensors...
May 26, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28722357/energy-migration-upconversion-in-ce-iii-doped-heterogeneous-core-shell-shell-nanoparticles
#4
Xian Chen, Limin Jin, Tianying Sun, Wei Kong, Siu Fung Yu, Feng Wang
One major challenge in upconversion research is to develop new materials and structures to expand the emission spectrum. Herein, a heterogeneous core-shell-shell nanostructure of NaYbF4 :Gd/Tm@NaGdF4 @CaF2 :Ce is developed to realize efficient photon upconversion in Ce(3+) ions through a Gd-mediated energy migration process. The design takes advantage of CaF2 host that reduces the 4f-5d excitation frequency of Ce(3+) to match the emission line of Gd(3+) . Meanwhile, CaF2 is isostructural with NaGdF4 and can form a continuous crystalline lattice with the core layer...
July 19, 2017: Small
https://www.readbyqxmd.com/read/28715763/quantification-of-the-limitation-of-langmuir-model-used-in-adsorption-research-on-sediments-via-site-energy-heterogeneity
#5
Qiang Jin, Limin Huang, Aimin Li, Aidang Shan
The Langmuir model has been extensively introduced into the field of environmental adsorption, while some studies showed that it was difficult for the model to describe the adsorption of sediments. The purpose of this paper is to recognize the applicability of the Langmuir model used in the adsorption of contaminants onto sediments quantitatively through the relationship between the error of Langmuir (δ) and site energy heterogeneity (σ). The formula for calculating δ in sediments was developed based on the heterogeneity parameters (m, n)...
July 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28713386/impairment-of-granzyme-b-producing-regulatory-b-cells-correlates-with-exacerbated-rheumatoid-arthritis
#6
Liling Xu, Xu Liu, Hongjiang Liu, Lei Zhu, Huaqun Zhu, Jian Zhang, Limin Ren, Pingzhang Wang, Fanlei Hu, Yin Su
Hyperactivated B cells have been demonstrated the contribution to the development of rheumatoid arthritis (RA). While the recognition of the negative regulatory function of B cells further promoted our understanding of their pathogenic role in RA. Recently, a new population of granzyme B (GrB)-producing B cells was identified, which was proved to be involved in cancer and infectious diseases. However, their characteristics and roles in RA remain to be elucidated. In the present study, we aim to further characterize whether B cells could produce GrB and reveal their potential role in the pathogenesis of RA...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28713329/prevalence-incidence-prognosis-early-stroke-risk-and-stroke-related-prognostic-factors-of-definite-or-probable-transient-ischemic-attacks-in-china-2013
#7
Bin Jiang, Haixin Sun, Xiaojuan Ru, Dongling Sun, Zhenghong Chen, Hongmei Liu, Yichong Li, Mei Zhang, Limin Wang, Linhong Wang, Shengping Wu, Wenzhi Wang
The epidemiological characteristics of transient ischemic attacks (TIAs) in China are unclear. In 2013, we conducted a nationally representative, door-to-door epidemiological survey on TIA in China using a complex, multistage, probability sampling design. Results showed that the weighted prevalence of TIA in China was 103.3 [95% confidence interval (CI): 83.9-127.2] per 100,000 in the population, 92.4 (75.0-113.8) per 100,000 among men, and 114.7 (87.2-151.0) per 100,000 among women. The weighted incidence of TIA was 23...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28712815/asymptomatic-carotid-stenosis-is-associated-with-cognitive%C3%A2-impairment
#8
Brajesh K Lal, Moira C Dux, Siddhartha Sikdar, Carly Goldstein, Amir A Khan, John Yokemick, Limin Zhao
BACKGROUND: Cerebrovascular risk factors (eg, hypertension, coronary artery disease) and stroke can lead to vascular cognitive impairment. The Asymptomatic Carotid Stenosis and Cognitive Function study evaluated the isolated impact of asymptomatic carotid stenosis (no prior ipsilateral or contralateral stroke or transient ischemic attack) on cognitive function. Cerebrovascular hemodynamic and carotid plaque characteristics were analyzed to elucidate potential mechanisms affecting cognition...
July 13, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28709639/ganoderma-triterpenes-retard-renal-cyst-development-by-downregulating-ras-mapk-signaling-and-promoting-cell-differentiation
#9
Limin Su, Liying Liu, Yingli Jia, Lei Lei, Jiangfeng Liu, Shuai Zhu, Hong Zhou, Ruoyun Chen, Hua Ann Jenny Lu, Baoxue Yang
Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenetic disease characterized by the progressive development of renal cysts with further need for effective therapy. Here our aim was to investigate the effect of Ganoderma triterpenes (GT) on the development of kidney cysts. Importantly, GT attenuated cyst development in two mouse models of ADPKD with phenotypes of severe cystic kidney disease. Assays for tubulogenesis showed that GT promoted epithelial tubule formation in MDCK cells, suggesting a possible effect on epithelial cell differentiation...
July 11, 2017: Kidney International
https://www.readbyqxmd.com/read/28708774/identifying-unilateral-disease-in-chinese-patients-with-primary-aldosteronism-by-using-a-modified-prediction-score
#10
Ying Zhang, Wenquan Niu, Fangfang Zheng, Hua Zhang, Wenlong Zhou, Zhoujun Shen, Jianzhong Xu, Xiaofeng Tang, Jin Zhang, Ping-Jin Gao, Ji-Guang Wang, Limin Zhu
OBJECTIVE: The current study aimed to evaluate the role of Küpers' score in predicting unilateral aldosteronism, and develop a modified score in Chinese patients with primary aldosteronism. METHODS: The current retrospective study included 406 patients with primary aldosteronism who underwent successful adrenal venous sampling (AVS) and were divided into the unilateral (n = 211) and bilateral (n = 195) groups according to the AVS results. Normokalemia was noted in both the unilateral (n = 64) and bilateral groups (n = 84) when plasma and urinary aldosterone were measured...
July 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28693885/post-exposure-treatment-with-the-oxime-rs194b-rapidly-reverses-early-and-advanced-symptoms-in-macaques-exposed-to-sarin-vapor
#11
Yvonne J Rosenberg, Lingjun Mao, Xiaoming Jiang, Jonathan Lees, Limin Zhang, Zoran Radic, Palmer Taylor
Organophosphate (OP) nerve agents and pesticides trigger a common mechanism of neurotoxicity resulting from critical targeting and inhibition of acetylcholinesterases (AChE) in central and peripheral synapses in the cholinergic nervous system. Therapeutic countermeasures have thus focused on either administering an oxime post-exposure, that can rapidly reactivate OP-inhibited AChE, or by preventing OP poisoning through administering pre-exposure treatments that scavenge OPs before they inhibit their physiological AChE targets...
July 8, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28692790/formation-of-mo-polydopamine-hollow-spheres-and-their-conversions-to-moo2-c-and-mo2-c-c-for-efficient-electrochemical-energy-storage-and-catalyst
#12
Chunli Wang, Lianshan Sun, Feifei Zhang, Xuxu Wang, Qujiang Sun, Yong Cheng, Limin Wang
Highly uniform hierarchical Mo-polydopamine hollow spheres are synthesized for the first time through a liquid-phase reaction under ambient temperature. A self-assembly mechanism of the hollow structure of Mo-polydopamine precursor is discussed in detail, and a determined theory is proposed in a water-in-oil system. Via different annealing process, these precursors can be converted into hierarchical hollow MoO2 /C and Mo2 C/C composites without any distortion in shape. Owing to the well-organized structure and nanosize particle embedding, the as-prepared hollow spheres exhibit appealing performance both as the anode material for lithium-ion batteries and as the catalyst for hydrogen evolution reaction (HER)...
July 10, 2017: Small
https://www.readbyqxmd.com/read/28692437/codelivery-of-salinomycin-and-docetaxel-using-poly-d-l-lactic-co-glycolic-acid-poly-ethylene-glycol-nanoparticles-to-target-both-gastric-cancer-cells-and-cancer-stem-cells
#13
Lan Li, Dejun Cui, Limin Ye, Yu Li, Liyi Zhu, Lanqun Yang, Banjun Bai, Zhao Nie, Jie Gao, Yu Cao
Cancer stem cells (CSCs) in gastric cancer (GC) have been established recently as key therapeutic targets for the successful treatment of GC. Emerging evidence suggests that both CSCs and cancer cells should be eradicated to achieve optimal therapeutic efficacy. In the present study, salinomycin, which has been reported to kill CSCs, was used in combination with docetaxel, a chemotherapeutic drug that is used as first-line therapy in GC, to eradicate both GC stem cells (SCs) and cancer cells. Salinomycin and docetaxel were loaded separately into poly(D,L-lactic-co-glycolic acid)-poly(ethylene glycol) nanoparticles of ∼140 nm with a narrow size distribution, high drug loading, and sustained drug release...
July 7, 2017: Anti-cancer Drugs
https://www.readbyqxmd.com/read/28687936/prevalence-of-lower-urinary-tract-symptoms-in-china-taiwan-and-south-korea-results-from-a-cross-sectional-population-based-study
#14
Christopher Chapple, David Castro-Diaz, Yao-Chi Chuang, Kyu-Sung Lee, Limin Liao, Shih-Ping Liu, Jianye Wang, Tag Keun Yoo, Romeo Chu, Budiwan Sumarsono
INTRODUCTION: Few population-based data are available evaluating the prevalence of lower urinary tract symptoms (LUTS) in Asia. The objective of our study was to determine LUTS prevalence in China, Taiwan, and South Korea using International Continence Society (ICS) 2002 criteria. METHODS: An Internet-based self-administered survey among individuals aged at least 40 years with the ability to use a computer and to read the local language. Survey questions included ICS symptom definitions and the international prostate symptom score (IPSS)...
July 7, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28686010/monoclinic-zif-8-nanosheets-derived-2d-carbon-nanosheets-as-sulfur-immobilizer-for-high-performance-lithium-sulfur-batteries
#15
Yi Jiang, Haiqiang Liu, Xinghua Tan, Limin Guo, Jiangtao Zhang, Shengnan Liu, Yanjun Guo, Juan Zhang, Hanfu Wang, Weiguo Chu
2D hierarchically porous carbon (2D-HPC) nanosheets with unique advantages are highly desired as host materials for lithium sulfur (Li-S) batteries and other energy storage devices. Herein, we propose a self-template and organic solvent-free approach to synthesize nanosheets of monoclinic ZIF-8 at room temperature from which 2D-HPC nanosheets (ZIF-8 Nanosheets Carbon denoted as ZIF-8-NS-C) are derived to be an efficient sulfur immobilizer for Li-S batteries for the first time. The anisotropic nanosheets are believed to relate to the symmetry of the monoclinic structure...
July 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28685403/the-change-of-cervical-spine-alignment-along-with-aging-in-asymptomatic-population-a-preliminary-analysis
#16
Yiwei Chen, Jiaquan Luo, Zhimin Pan, Limin Yu, Long Pang, Junlong Zhong, Zhiyun Li, Zhimin Han, Kai Cao
STUDY DESIGN: A cross-sectional study. OBJECTIVE: To investigate the correlation of cervical spine alignment changes with aging in asymptomatic population. BACKGROUND: Previous studies demonstrated the influence of lumbar and thoracic spine on cervical spine alignment, but few has reported the cervical spine alignment change along with aging in asymptomatic population. METHODS: Asymptomatic population were divided into four groups according to different ages (Group A: ≤20 years; Group B: 21-40 years; Group C: 41-60 years; Group D: ≥61 years)...
July 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28683239/comparison-of-efficacy-and-safety-of-glargine-and-detemir-insulin-in-the-management-of-inpatient-hyperglycemia-and-diabetes
#17
Rodolfo J Galindo, Georgia M Davis, Maya Fayfman, David Reyes-Umpierrez, David Alfa, Limin Peng, Ronald Tamler, Francisco J Pasquel, Guillermo E Umpierrez
OBJECTIVE: Glargine and detemir insulin are the two most commonly prescribed basal insulin analogs for the ambulatory and inpatient management of diabetes. The efficacy and safety of basal insulin analogs in the hospital setting has not been established. METHODS: This observational study compared differences in glycemic control and outcomes in non-ICU patients with blood glucose (BG) >140 mg/dl who were treated with glargine or detemir, between 01/01/2012 and 09/30/2015 in two academic centers...
July 6, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28683082/the-herbal-decoction-modified-danggui-buxue-tang-attenuates-immune-mediated-bone-marrow-failure-by-regulating-the-differentiation-of-t-lymphocytes-in-an-immune-induced-aplastic-anemia-mouse-model
#18
Peiying Deng, Xue Li, Yi Wei, Juan Liu, Meng Chen, Yamei Xu, Bin Dong, Lingqun Zhu, Limin Chai
Angelicae Sinensis, Radix Astragali and Rhizoma Coptidis are all herbs of modified Danggui Buxue Tang (DGBX) and are extensively applied herbs in traditional Chinese medicine for the treatment of anemia and inflammation. In this study, immune-induced AA mice were used as an animal model, and the immunosuppressive agent, Ciclosporin A (CsA), was used as a positive control. Multiple pro-inflammatory cytokines were examined by bead-based multiplex flow cytometry. The T-cell subsets were assessed using a fluorescence-activated cell sorter (FACS)...
2017: PloS One
https://www.readbyqxmd.com/read/28682875/the-use-of-3d-printed-titanium-mesh-tray-in-treating-complex-comminuted-mandibular-fractures-a-case-report
#19
Junli Ma, Limin Ma, Zhifa Wang, Xiongjie Zhu, Weijian Wang
RATIONALE: Precise bony reduction and reconstruction of optimal contour in treating comminuted mandibular fractures is very difficult using traditional techniques and devices. The aim of this report is to introduce our experiences in using virtual surgery and three-dimensional (3D) printing technique in treating this clinical challenge. PATIENT CONCERNS: A 26-year-old man presented with severe trauma in the maxillofacial area due to fall from height. DIAGNOSIS: Computed tomography images revealed middle face fractures and comminuted mandibular fracture including bilateral condyles...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28680810/fluoride-resistance-capacity-in-mammalian-cells-involves-complex-global-gene-expression-changes
#20
Shujun Ran, Ning Sun, Yun Liu, Wu Zhang, Yiming Li, Limin Wei, Jia Wang, Bin Liu
Fluorine is a bone-seeking element ubiquitously present in the environment and widely used in many oral hygiene products. In humans, excessive intake of fluoride may cause dental and skeletal fluorosis. However, endemic fluorosis does not appear to develop in a proportion of individuals exposed to the same levels of fluoride. The mechanisms by which mammalian cells resist fluoride are still unclear. In this study, we developed strains of mouse L-929 cells resistant to different levels of fluoride. High-throughput RNA-sequencing analyses of the fluoride-resistant L-929 cells indicated that massive changes in global gene expression occurred, compared with the wild-type L-929 cells...
July 2017: FEBS Open Bio
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