Read by QxMD icon Read

"Skin cancer screening"

Y Fujisawa, Y Otomo, Y Ogata, Y Nakamura, R Fujita, Y Ishitsuka, R Watanabe, N Okiyama, K Ohara, M Fujimoto
BACKGROUND: Application of deep-learning technology to skin cancer classification can potentially improve skin cancer screening sensitivity and specificity, but the number of training images required for such system is thought to be extremely large. OBJECTIVE: To determine if deep-learning technology could be used to develop an efficient skin cancer classifying system with a relatively small dataset of clinical images. METHODS: A deep convolutional neural network (DCNN) was trained using a dataset of 4867 clinical images obtained from 1842 patients diagnosed with skin tumors at the University of Tsukuba Hospital from 2003 to 2016...
June 14, 2018: British Journal of Dermatology
Patricia Markham Risica, Natalie H Matthews, Laura Dionne, Jennifer Mello, Laura K Ferris, Melissa Saul, Alan C Geller, Francis Solano, John M Kirkwood, Martin A Weinstock
Screening for melanoma may save lives, but may also cause patient distress. One key reason that preventative visual skin examinations for skin cancer are not currently recommended is the inadequate available evidence to assess potential harm to psychosocial wellbeing. We investigated potential psychological harms and benefits of skin examinations by conducting telephone surveys in 2015 of 187 screened participants; all were ≥35 years old. Participants had their skin examined by practitioners who had completed INFORMED, a validated web-based training for detection of skin cancers, particularly melanoma...
June 2018: Preventive Medicine Reports
Alexander Zink, Frank Thome, Maximilian Schielein, Christoph D Spinner, Tilo Biedermann, Linda Tizek
BACKGROUND: Outdoor professionals such as mountain guides are at a substantial risk of developing non-melanoma skin cancer (NMSC) due to solar ultraviolet radiation (UVR) exposure. Despite major recent primary prevention efforts, studies on secondary skin cancer prevention efforts are limited and corresponding data on outdoor workers scarce. OBJECTIVE: To assess the sun-protective behavior and individual motivations for or against skin cancer screening examinations in the German mountain guide population to aid in the development of effective awareness and prevention strategies...
May 30, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
A Zink, L Tizek, M Schielein, A Böhner, T Biedermann, M Wildner
BACKGROUND: One of the main risk factors for non-melanoma skin cancer (NMSC), the most common cancer worldwide, is solar ultraviolet radiation (UVR). This has led to the recognition of NMSC as occupational disease for outdoor workers in several countries. However, outdoor professions are a very heterogeneous group with diverse daily activities and associated UVR exposure. OBJECTIVE: To compare the prevalence of NMSC and associated risk behaviour in different outdoor professions...
May 27, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
Alyce Anderson, Laura K Ferris, Benjamin Click, Claudia Ramos-Rivers, Ioannis E Koutroubakis, Jana G Hashash, Michael Dunn, Arthur Barrie, Marc Schwartz, Miguel Regueiro, David G Binion
BACKGROUND: Dermatologic manifestations of inflammatory bowel disease (IBD) are common, and certain IBD medications increase the risk of skin cancer. AIMS: To define the rates of care and factors associated with dermatologic utilization with a focus on skin cancer screening. METHODS: We utilized a prospective, natural history IBD research registry to evaluate all outpatient healthcare encounters from 2010 to 2016. Gastrointestinal, dermatologic and primary care visits per individual were identified...
April 30, 2018: Digestive Diseases and Sciences
Alyce M Anderson, Martha Matsumoto, Melissa I Saul, Aaron M Secrest, Laura K Ferris
Importance: Physician assistants (PAs) are increasingly used in dermatology practices to diagnose skin cancers, although, to date, their diagnostic accuracy compared with board-certified dermatologists has not been well studied. Objective: To compare diagnostic accuracy for skin cancer of PAs with that of dermatologists. Design, Setting, and Participants: Medical record review of 33 647 skin cancer screening examinations in 20 270 unique patients who underwent screening at University of Pittsburgh Medical Center-affiliated dermatology offices from January 1, 2011, to December 31, 2015...
May 1, 2018: JAMA Dermatology
V Lang, F Lauffer, Y Fincan, T Biedermann, A Zink
BACKGROUND: Skin diseases affect 30-70% of the world population, and globally, skin cancer rates are continuously increasing. In this respect, prevention programs and early detection of skin diseases are of particular importance. OBJECTIVES: To screen sewer workers for skin diseases with regard to their work-related risk. METHODS: Employees of the municipal utilities in Munich (Münchner Stadtentwässerung) underwent a whole-body examination of the skin, conducted by two dermatologists...
April 25, 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
Joseph F Sobanko, Kimberly Shao, Rebecca L Pearl, Sancy Leachman
The United States Preventive Services Task Force (USPSTF) 2016 recommendation for skin cancer screening in asymptomatic healthy adults concluded that current evidence is "insufficient to assess the balance and harms of visual skin examination." One contributing factor leading to the insufficient grade was a concern for cosmetic harms resulting from unnecessary biopsies or excisions. This commentary briefly highlights the pertinent studies and currently accepted methods for pigmented lesion biopsy...
April 2018: Journal of Clinical and Aesthetic Dermatology
D Jäckel, N I Schlothauer, H Zeeb, G Wagner, M M Sachse
BACKGROUND: Organ transplant recipients have an up to 250-times higher risk to develop skin cancer. This article evaluated the utilisation of skin cancer screening and the treatment costs for skin cancer in organ transplant recipients. Patients of the health insurance AOK Bremen/Bremerhaven had been identified and the need for skin cancer prevention trainings was derived. METHODS: The number of organ transplant recipients (ICD code Z94.0-4) with and without any history of skin cancer (ICD code C43/C44), the utilisation of dermatologic health care services, and the costs for treatments with the diagnosis Z94...
April 12, 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
Amir Varedi, Aaron M Secrest, Garrett Harding, Lori Maness, Donna Branson, Kristi Smith, Christopher M Hull
Outdoor recreation can lead to substantial sun exposure. Employees of outdoor recreation establishments with extended time outdoors have amplified cumulative exposure to ultraviolet (UV) radiation and an increased risk of skin cancer. The "Sun Safe on the Slopes" program was created by Huntsman Cancer Institute at the University of Utah and the Utah Cancer Action Network to address increased UV exposure and skin cancer risk with free skin cancer screenings, outreach, and prevention education to local ski resorts...
February 15, 2018: Dermatology Online Journal
Mary K Tripp
No abstract text is available yet for this article.
May 1, 2018: JAMA Dermatology
Carolyn J Heckman, Elizabeth Handorf, Melissa V Auerbach
Importance: The US Food and Drug Administration recommends that indoor tanners (ITs) be screened regularly for skin cancer (SC). Objective: To investigate the association between indoor tanning and SC screening. Design, Setting, and Participants: The 2015 National Health Interview Survey was a multistage, clustered, cross-sectional design with 30 352 US adults participating. The response rate for the sample adult data used in this study was 55...
May 1, 2018: JAMA Dermatology
Valérie Zimmerlé, Emeline Laurent, Valérie Tauveron, Annabel Maruani, Emmanuelle Le Bidre, Mahtab Samimi, Laurent Machet
INTRODUCTION: Cutaneous cancers are very common, easily visible on skin. The general practitioner (GP) is in the front line to manage the lesions. He has to recognize malignancy and refer most often to the specialist for excision, or consider that the lesion is benign and in ambiguous cases, offer clinical monitoring. The current low medical density in the Centre Val de Loire area makes access to general practitioners (GP) and dermatologists harder. The aim of this study was to evaluate GPs' everyday practice in cutaneous cancers screening in general, and particularly in melanoma screening, in a rural region of France...
April 2018: La Presse Médicale
Alexandra Price, Jessica Cervantes, Scott Lindsey, Divya Aickara, Shasa Hu
Nail-patella syndrome (NPS) is a rare autosomal-dominant disorder characterized by the classic triad of fingernail dysplasia, patellar absence/hypoplasia, and presence of iliac horns. We describe the various features of NPS, focusing on dermatologic and musculoskeletal findings. A 69-year-old man presented to the dermatology clinic for a routine skin cancer screening. Physical examination revealed hypoplastic fingernails with longitudinal ridging, splitting, and triangular lunulae; left patellar absence and right patellar hypoplasia; and bilateral iliac horns that had been present since birth...
February 2018: Cutis; Cutaneous Medicine for the Practitioner
Mark H Ebell, Thuy Nhu Thai, Kyle J Royalty
Background: Recommendations regarding cancer screening vary from country to country, and may also vary within countries depending on the organization making the recommendations. The goal of this study was to summarize the cancer screening recommendations from the 21 countries with the highest per capita spending on healthcare. Main body: Cancer screening guidelines were identified for each country based on a review of the medical literature, internet searches, and contact with key informants in most countries...
2018: Public Health Reviews
Marike M Leijs, André Esser, Philipp M Amann, Thomas Schettgen, Monika Gube, Hans F Merk, Thomas Kraus, Jens M Baron
Polychlorinated biphenyls (PCB) are well known persistent and toxic environmental pollutants. Our aim was to identify effects of moderate-high exposure to dioxin-like (dl) and non-dioxin-like (ndl)-PCBs on the skin in order to provide more insight in the pathophysiological effects of these compounds. We performed a dermatological examination on 92 former workers from a transformer recycling company with known elevated serum PCB and/or dioxin (polychlorinated dibenzo-p-dioxin/polychlorinated dibenzo-p-furan (PCDD/F)) levels...
July 2018: Environmental Research
Janin Lehmann, Christina Seebode, Marie Christine Martens, Steffen Emmert
Ultraviolet (UV)-induced DNA lesions are almost exclusively removed by the nucleotide excision repair (NER) pathway, which is essential for prevention of skin cancer development. Patients with xeroderma pigmentosum (XP) are extremely sun sensitive due to a genetic defect in components of the NER cascade. They present with first signs of premature skin aging at an early age, with a considerably increased risk of developing UV-induced skin cancer. XP belongs to the group of DNA repair defective disorders that are mainly diagnosed in the clinic and in hindsight confirmed at the molecular level...
February 2018: Anticancer Research
Marie Christine Martens, Christina Seebode, Janin Lehmann, Steffen Emmert
UV radiation is acknowledged as the primary cause of photocarcinogenesis and therefore contributes to the development of skin cancer entities such as squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and melanoma. Typical DNA photoproducts and indirect DNA damage caused by reactive oxygen species are the result of UV radiation. UV-induced DNA damage is repaired by nucleotide excision repair, which consequently counteracts the development of mutations and skin carcinogenesis. Tumour-suppressor genes are inactivated by mutation and growth-promoting pathways are activated leading to disruption of cell-cycle progression...
February 2018: Anticancer Research
Arthur Varkentin, Mikhail Mazurenka, Elias Blumenröther, Lea Behrendt, Steffen Emmert, Uwe Morgner, Merve Meinhardt-Wollweber, Maik Rahlves, Bernhard Roth
A new multimodal system for rapid, noninvasive in vivo skin cancer screening is presented, combining optical coherence tomography (OCT) and optoacoustic (OA) modalities to provide precise tumor depth determination with a Raman spectroscopic modality capable of detecting the lesion type and, thus, providing diagnostic capability. Both OA and Raman setups use wide field skin illumination to ensure the compliance with maximum permissible exposure (MPE) requirements. The Raman signal is collected via the OCT scanning lens to maximize the signal-to-noise ratio of the measured signal while keeping radiation levels below MPE limits...
January 23, 2018: Journal of Biophotonics
Joshua W Hagen, Melissa A Pugliano-Mauro
BACKGROUND: Azathioprine and 6-mercaptopurine (thiopurines) are common adjunct treatments for inflammatory bowel disease (IBD). Although thiopurine therapy in organ transplant recipients is known to increase nonmelanoma skin cancers (NMSCs), dermatologic literature yields less data regarding NMSC risk of thiopurine use in IBD. OBJECTIVE: The aim of this study was to systematically review current literature on NMSC risk in patients with IBD using thiopurine therapy...
April 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"