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https://www.readbyqxmd.com/read/29772204/tau-kinetics-in-neurons-and-the-human-central-nervous-system
#1
Chihiro Sato, Nicolas R Barthélemy, Kwasi G Mawuenyega, Bruce W Patterson, Brian A Gordon, Jennifer Jockel-Balsarotti, Melissa Sullivan, Matthew J Crisp, Tom Kasten, Kristopher M Kirmess, Nicholas M Kanaan, Kevin E Yarasheski, Alaina Baker-Nigh, Tammie L S Benzinger, Timothy M Miller, Celeste M Karch, Randall J Bateman
No abstract text is available yet for this article.
May 16, 2018: Neuron
https://www.readbyqxmd.com/read/29761724/characterization-of-the-microbiota-in-air-or-vacuum-packed-crisp-grass-carp-ctenopharyngodon-idella-c-et-v-fillets-by-16s-rrna-pcr-denaturing-gradient-gel-electrophoresis-and-high-throughput-sequencing
#2
Ziqiang Pan, Lin Li, Zhihua Shen, Yan Chen, Mei Li
The microbial communities in air- and vacuum-packed crisp grass carp ( Ctenopharyngodon idella C. et V.) fillets have not been characterized during chilled storage. High-throughput sequencing of bacterial 16S rRNA has now revealed that the bacterial community in fresh fillets is diverse and distinct from that in spoiled samples. The predominant phylum was Proteobacteria, and 66 genera were identified. In fresh fillets, the most abundant genera were Acinetobacter (53.3%), Wautersiella (6.3%), unclassified Alcaligenaceae (4...
May 15, 2018: Journal of Food Protection
https://www.readbyqxmd.com/read/29729992/proteomics-functional-characterization-and-antivenom-neutralization-of-the-venom-of-pakistani-russell-s-viper-daboia-russelii-from-the-wild
#3
Tasnim Faisal, Kae Yi Tan, Si Mui Sim, Naeem Quraishi, Nget Hong Tan, Choo Hock Tan
The venom proteome of wild Pakistani Russell's viper (Daboia russelii) was investigated through nano-ESI-LCMS/MS of the reverse-phase HPLC fractions. A total of 54 venom proteins were identified and clustered into 11 protein families. Phospholipase A2 (PLA2 , 63.8%) and Kunitz-type serine protease inhibitor (KSPI, 16.0%) were most abundant, followed by snake venom serine protease (SVSP, 5.5%, mainly Factor V activating enzyme), vascular endothelial growth factor (VEGF, 4.3%), snake venom metalloprotease (SVMP, 2...
May 3, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29727398/work-ability-trajectories-and-retirement-pathways-a-longitudinal-analysis-of-older-american-workers
#4
Michael Boissonneault, Joop de Beer
OBJECTIVE: To determine whether older workers who follow different work ability (WA) trajectories tend to follow different retirement pathways. METHODS: Nationally representative data on Americans born between 1943 and 1948. Latent class growth modelling to estimate trajectories of work ability between ages 53-54 and 65-66. Multinomial log-linear models to assess the association between WA trajectories and retirement pathways. RESULTS: Three WA trajectories were identified: high (74%), declining (17%) and low (9%)...
May 2, 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29707792/maintenance-of-pre-existing-dna-methylation-states-through-recurring-excess-light-stress
#5
Diep R Ganguly, Peter A Crisp, Steven R Eichten, Barry J Pogson
The capacity for plant stress priming and memory, and the notion of this being underpinned by DNA methylation-mediated memory is an appealing hypothesis for which there is mixed evidence. We previously established a lack of drought-induced methylome variation in Arabidopsis thaliana (Arabidopsis); however, this was tied to only minor observations of physiological memory. There are numerous independent observations demonstrating that photoprotective mechanisms, induced by excess-light (EL) stress, can lead to robust programmable changes in newly developing leaf tissues...
April 29, 2018: Plant, Cell & Environment
https://www.readbyqxmd.com/read/29707670/morphological-changes-and-induction-of-antifungal-resistance-in-aspergillus-fumigatus-due-to-different-co2-levels
#6
Sima Darabian, Sayed Jamal Hashemi, Sadegh Khodavaisy, Somayeh Sharifynia, Mohammad Kord, Maryam Akbari Dana, Farzad Aala, Sassan Rezaie
Background and Purpose: Aspergillosis is one of the most common opportunistic fungal infections in immunocompromised and neutropenic patients. Aspergillus fumigatus ( A. fumigatus ) is the most common causative agent of this infection. Due to variable CO2 concentrations that pathogens are exposed to during the infection process and to understand the role of CO2 , we examined the effects of various CO2 concentrations as one of the environmental factors on morphological changes and induction of antifungal resistance in A...
September 2017: Advances in Medical Mycology (Iran)
https://www.readbyqxmd.com/read/29705756/cohort-profile-china-respiratory-illness-surveillance-among-pregnant-women-crisp-2015-2018
#7
Liling Chen, Suizan Zhou, Zhongwei Zhang, Yan Wang, Lin Bao, Yayun Tan, Falin Sheng, Ying Song, Ran Zhang, A Danielle Iuliano, Mark G Thompson, Carolyn M Greene, Jun Zhang
PURPOSE: We established the China Respiratory Illness Surveillance among Pregnant women (CRISP) to conduct active surveillance for influenza-associated respiratory illness during pregnancy in China from 2015 to 2018. Among annual cohorts of pregnant women, we assess the incidence of acute respiratory illness (ARI), influenza-like illness (ILI), laboratory-confirmed influenza virus infection and the seroconversion proportion during the winter influenza season. We also plan to examine the effect of influenza virus infection on adverse pregnancy, delivery and infant health outcomes with cumulative data from the three annual cohorts...
April 28, 2018: BMJ Open
https://www.readbyqxmd.com/read/29705149/assessment-of-the-potential-toxicological-hazard-of-the-green-parrot-snake-leptophis-ahaetulla-marginatus-characterization-of-its-venom-and-venom-delivery-system
#8
Matías N Sánchez, Gladys P Teibler, Carlos A López, Stephen P Mackessy, María E Peichoto
Snakes are the major group of venomous vertebrates, and the rear-fanged snakes represent the vast majority of species and occur worldwide; however, relatively few studies have characterized their venoms and evaluated their potential hazards for humans. Herein we explore the protein composition and properties of the venom of the rear-fanged Green Parrot Snake, Leptophis ahaetulla marginatus, the most common snake found in the Iguazu National Park (Argentina), as well as the main features of its venom delivery system...
April 26, 2018: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29699650/extruded-flour-improves-batter-pick-up-coating-crispness-and-aroma-profile
#9
Laura Román, Joana Pico, Beatriz Antolín, Mario M Martinez, Manuel Gómez
Fried battered foods are widely consumed worldwide. In this study, the influence of the replacement of native wheat flour by extruded flours (7.5 and 15%) subjected to different extrusion severities on chicken nuggets was assessed. Microstructure, pick-up, moisture and fat content, texture, colour, volatile profile, and consumer acceptability were evaluated. Extruded flour replacement resulted in batters with improved pick-up with increasing percentage and severity of extrusion treatment. Extruded flour also contributed to a moisture increase, while oil remained practically unchanged...
September 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29689044/comparative-genomics-of-bdelloid-rotifers-insights-from-desiccating-and-nondesiccating-species
#10
Reuben W Nowell, Pedro Almeida, Christopher G Wilson, Thomas P Smith, Diego Fontaneto, Alastair Crisp, Gos Micklem, Alan Tunnacliffe, Chiara Boschetti, Timothy G Barraclough
Bdelloid rotifers are a class of microscopic invertebrates that have existed for millions of years apparently without sex or meiosis. They inhabit a variety of temporary and permanent freshwater habitats globally, and many species are remarkably tolerant of desiccation. Bdelloids offer an opportunity to better understand the evolution of sex and recombination, but previous work has emphasised desiccation as the cause of several unusual genomic features in this group. Here, we present high-quality whole-genome sequences of 3 bdelloid species: Rotaria macrura and R...
April 2018: PLoS Biology
https://www.readbyqxmd.com/read/29680623/enhancement-of-water-removing-and-the-quality-of-fried-purple-fleshed-sweet-potato-in-the-vacuum-frying-by-combined-power-ultrasound-and-microwave-technology
#11
Ya Su, Min Zhang, Bhesh Bhandari, Weiming Zhang
The combination of ultrasound and microwave in vacuum frying system was investigated to achieve higher drying efficiency and quality attributes of fried products. Purple-fleshed potato were used as test specimen and different power levels of microwave (0 W, 600 W, 800 W) and ultrasound (0 W, 300 W, 600 W) during vacuum frying. Drying kinetics, dielectric properties, moisture state variation and quality attributes of fried samples were measured in a vacuum frying (VF), and an innovatively designed ultrasound and microwave assisted vacuum frying (USMVF) equipment...
June 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29676932/exoplanet-biosignatures-a-framework-for-their-assessment
#12
David C Catling, Joshua Krissansen-Totton, Nancy Y Kiang, David Crisp, Tyler D Robinson, Shiladitya DasSarma, Andrew J Rushby, Anthony Del Genio, William Bains, Shawn Domagal-Goldman
Finding life on exoplanets from telescopic observations is an ultimate goal of exoplanet science. Life produces gases and other substances, such as pigments, which can have distinct spectral or photometric signatures. Whether or not life is found with future data must be expressed with probabilities, requiring a framework of biosignature assessment. We present a framework in which we advocate using biogeochemical "Exo-Earth System" models to simulate potential biosignatures in spectra or photometry...
April 20, 2018: Astrobiology
https://www.readbyqxmd.com/read/29675969/exercise-induced-pulmonary-haemorrhage-in-thoroughbred-racehorses-a-longitudinal-study
#13
E J Crispe, C J Secombe, D I Perera, A A Manderson, B A Turlach, G D Lester
BACKGROUND: Exercise induced pulmonary haemorrhage (EIPH) is considered a progressive disease based on histopathology, but it is unknown if tracheobronchoscopic EIPH severity worsens over time. OBJECTIVES: The aim of this study was to examine tracheobronchoscopic EIPH changes over time in a population of Thoroughbred racehorses. A secondary aim was to identify factors that affect changes in tracheobronchoscopic EIPH severity between observations. STUDY DESIGN: Prospective, longitudinal, observational cross-sectional study...
April 20, 2018: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29664600/asymmetric-optical-transitions-determine-the-onset-of-carrier-multiplication-in-lead-chalcogenide-quantum-confined-and-bulk-crystals
#14
Frank C M Spoor, Gianluca Grimaldi, Christophe Delerue, Wiel H Evers, Ryan W Crisp, Pieter Geiregat, Zeger Hens, Arjan J Houtepen, Laurens D A Siebbeles
Carrier multiplication is a process in which one absorbed photon excites two or more electrons. This is of great promise to increase the efficiency of photovoltaic devices. Until now, the factors that determine the onset energy of carrier multiplication have not been convincingly explained. We show experimentally that the onset of carrier multiplication in lead chalcogenide quantum confined and bulk crystals is due to asymmetric optical transitions. In such transitions most of the photon energy in excess of the band gap is given to either the hole or the electron...
April 17, 2018: ACS Nano
https://www.readbyqxmd.com/read/29660198/food-advertising-on-australian-television-frequency-duration-and-monthly-pattern-of-advertising-from-a-commercial-network-four-channels-for-the-entire-2016
#15
Lisa G Smithers, Dandara G Haag, Benjamin Agnew, John Lynch, Matthew Sorell
AIM: To estimate the frequency, duration and monthly pattern of discretionary food advertising on Australian free-to-air television. METHODS: We logged 30 000 h of television collected in Adelaide during 2016 from one network that has four channels. The Australian Guide to Healthy Eating was used to identify discretionary foods. Data were examined according to all times, to children's peak viewing times (PVTs) and to when C-(children's) rated programmes may be broadcast...
April 16, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29656017/proteomic-and-toxinological-characterization-of-the-venom-of-the-south-african-ringhals-cobra-hemachatus-haemachatus
#16
Andrés Sánchez, María Herrera, Mauren Villalta, Daniela Solano, Álvaro Segura, Bruno Lomonte, José María Gutiérrez, Guillermo León, Mariángela Vargas
The protein composition and toxinological profile of the venom of the African spitting elapid Hemachatus haemachatus (Ringhals) were characterized by bottom-up proteomics and functional in vitro and in vivo assays. Venom is composed of abundant three-finger toxins (3FTxs; 63.3%), followed by phospholipases A2 (PLA2 s; 22.8%), snake venom metalloproteinases (SVMPs 7.1%), cysteine-rich secretory proteins (CRISPs; 4.1%) and Kunitz type protease inhibitors (KTPIs; 1.5%). 3FTxs are the main responsible for lethality and myotoxicity in mice and in vitro anticoagulant activity...
April 12, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29621846/the-crisp-q-study
#17
Grace Y Kim, Jennifer Walker, Adrian Bickerstaffe, Nadira Hewabandu, Marie Pirotta, Louisa Flander, Mark Jenkins, Jon Emery
This research will inform approaches to communicating risk in CRISP and may be of wider relevance to supporting informed decisions about cancer screening. <div class="hor-line">&nbsp;</div>.
March 2018: Australian journal of general practice
https://www.readbyqxmd.com/read/29581341/time-from-imaging-to-endovascular-reperfusion-predicts-outcome-in-acute-stroke
#18
Jenny P Tsai, Michael Mlynash, Soren Christensen, Stephanie Kemp, Sun Kim, Nishant K Mishra, Christian Federau, Raul G Nogueira, Tudor G Jovin, Thomas G Devlin, Naveed Akhtar, Dileep R Yavagal, Roland Bammer, Matus Straka, Gregory Zaharchuk, Michael P Marks, Gregory W Albers, Maarten G Lansberg
BACKGROUND AND PURPOSE: This study aims to describe the relationship between computed tomographic (CT) perfusion (CTP)-to-reperfusion time and clinical and radiological outcomes, in a cohort of patients who achieve successful reperfusion for acute ischemic stroke. METHODS: We included data from the CRISP (Computed Tomographic Perfusion to Predict Response in Ischemic Stroke Project) in which all patients underwent a baseline CTP scan before endovascular therapy...
April 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29580111/the-african-american-eye-disease-study-design-and-methods
#19
Roberta McKean-Cowdin, Alicia Fairbrother-Crisp, Mina Torres, Carlos Lastra, Farzana Choudhury, Xuejuan Jiang, Bruce Burkemper, Rohit Varma
PURPOSE: To describe the study design, operational and recruitment strategies, procedures, and baseline characteristics of the African American Eye Disease Study (AFEDS), a population-based assement of the prevalence of visual impairment, ocular disease, visual function, and health-related quality of life in African Americans. METHODS: This population-based, cross-sectional study included over 6000 African Americans 40 years and older residing in and around Inglewood, California...
March 26, 2018: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/29579984/inter-correlation-of-apple-firmness-determinations-and-development-of-cross-validated-regression-models-for-prediction-of-sensory-attributes-from-instrumental-and-compositional-analyses
#20
Margaret A Cliff, Masoumeh Bejaei
The texture of apples is paramount for determining fruit quality. This research explored the correlations among firmness determinations from the Sinclair iQ™ Firmness Tester (SiQ™), the Aweta Acoustic Firmness Sensor (AFS), and eight measurements from the Mohr Digi-Test-2 (MDT) instrument. Assessments were conducted on a collection of nine apple cultivars (Ambrosia, Aurora Golden Gala™, Honeycrisp, Fuji, Imperial Gala, McIntosh, Pink Lady™, Silken, Salish™), with a broad range of firmness values, in each of two years...
April 2018: Food Research International
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