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https://www.readbyqxmd.com/read/29933345/force-length-relationship-modelling-of-wrist-and-finger-flexor-muscles
#1
Hugo Hauraix, Benjamin Goislard de Monsabert, Alexis Herbaut, Eric Berton, Laurent Vigouroux
INTRODUCTION: Because the hand joints possess a broad range of motion, the muscle length can vary importantly which might result in significant variations of the muscle force-generating capacities. However, facing the complexity of this musculoskeletal system, no study has examined the effect of hand muscles length change on muscle force. This study aimed to characterize the force-length relationship of muscles involved in wrist and metacarpophalangeal (MCP) flexion. METHODS: Eleven participants performed two sessions: i) one for the wrist flexor muscles, and ii) one for the finger flexor muscles...
June 21, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29933094/phenol-neurolysis-for-management-of-shoulder-spasticity-in-early-recovery-from-traumatic-brain-injury-a-case-report
#2
Manuel F Mas, Craig DiTommaso, Sheng Li
This case describes a 16-year-old boy who suffered a severe traumatic brain injury. The patient gradually recovered but developed debilitating spasticity mainly in left triceps muscle, abnormal positioning of shoulder girdle complex, and shoulder pain. Phenol (6%) was injected to axillary and radial nerves under guidance of electrical stimulation and ultrasound imaging at 10 weeks after initial injury. After injection, triceps spasticity and shoulder pain was immediately reduced and abnormal positions of shoulder girdle complex and elbow joint gradually returned to functional limits over 2 weeks...
June 19, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29932772/oxygen-availability-and-skeletal-muscle-oxidative-capacity-in-patients-with-peripheral-arterial-disease-implications-from-in-vivo-and-in-vitro-assessments
#3
Corey R Hart, Gwenael Layec, Joel D Trinity, Yann Le Fur, Jayson R Gifford, Heather L Clifton, Russell S Richardson
Evidence suggests that peak skeletal muscle mitochondrial ATP synthesis rate (Vmax ) in patients with peripheral arterial disease (PAD) may be attenuated due to disease-related impairments in oxygen (O2 ) supply. However, in vitro assessments suggest intrinsic deficits in mitochondrial respiration despite ample O2 availability. To address this conundrum, Doppler ultrasound, near infrared spectroscopy (NIRS), phosphorus magnetic resonance spectroscopy (31 P-MRS), and high-resolution respirometry were combined to assess convective O2 delivery, tissue oxygenation, Vmax , and skeletal muscle mitochondrial capacity (Complex I+II, State 3 respiration), respectively, in the gastrocnemius muscle of 10 patients with early-stage PAD and 11 physical activity-matched healthy controls (HC)...
June 22, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29931483/changes-in-the-sensorimotor-system-and-semitendinosus-muscle-morphometry-after-arthroscopic-anterior-cruciate-ligament-reconstruction-a-prospective-cohort-study-with-1-year-follow-up
#4
Marialuisa Gandolfi, Matteo Ricci, Elena Sambugaro, Nicola Valè, Eleonora Dimitrova, Andrea Meschieri, Silvano Grazioli, Alessandro Picelli, Calogero Foti, Francesco Rulli, Nicola Smania
PURPOSE: To evaluate the time course of sensorimotor integration processes involved in balance capability during 1-year follow-up after arthroscopic anterior cruciate ligament (ACL) reconstruction. To evaluate whether an association exists between balance performance and semitendinosus muscle morphometry features. METHODS: Twenty-seven patients (mean age 29.6 ± 10.8 years) were prospectively followed with stabilometry and ultrasound at 3 months (T0), 6 months (T1), and 1 year (T2) after arthroscopic ACL reconstruction...
June 21, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29924774/-contrast-enhanced-ultrasonographic-study-in-patients-with-lower-limb-arterial-lesions
#5
I E Timina, N N Askerova, G G Karmazanovskiĭ, I I Piatkova, A E Zotikov
BACKGROUND: The introduction into clinical practice of contrast-enhanced ultrasonographic examination made it possible to assess patency of tibial arteries and perfusion of crural muscles in patients with occlusive lesions of lower-limb arteries. These findings are important for planning optimal treatment policy and assessing efficacy of operative or medicamentous treatment. OBJECTIVE: The study was aimed at investigating a possibility of contrast-enhanced ultrasound examination for assessment of patency of tibial arteries and quantitative assessment of perfusion of crural muscles in patient with occlusive lesions of lower-limb arteries...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29923952/a-cadaver-study-investigating-structures-encountered-by-the-needle-during-a-retroclavicular-approach-to-infraclavicular-brachial-plexus-block
#6
Sushil F Sancheti, Vishal Uppal, Robert Sandeski, M Kwesi Kwofie, Jennifer J Szerb
BACKGROUND AND OBJECTIVES: Retroclavicular block is designed to overcome the negative aspects of the commonly utilized ultrasound-guided parasagittal approach to the infraclavicular block. However, this approach necessitates the needle traversing an area posterior to the clavicle inaccessible to ultrasound wave conduction. This study sought to document the structures vulnerable to needle injury during a retroclavicular block. METHODS: A Tuohy needle was inserted using a retroclavicular approach to the infraclavicular block in 3 lightly embalmed cadavers followed by a catheter insertion 4 cm beyond the needle tip...
June 19, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29921611/smggds-prevents-thoracic-aortic-aneurysm-formation-and-rupture-by-phenotypic-preservation-of-aortic-smooth-muscle-cells
#7
Masamichi Nogi, Kimio Satoh, Shinichiro Sunamura, Nobuhiro Kikuchi, Taijyu Satoh, Ryo Kurosawa, Junichi Omura, Md Elias Al-Mamun, Mohammad Abdul Hai Siddique, Kazuhiko Numano, Shun Kudo, Satoshi Miyata, Masatoshi Akiyama, Kiichiro Kumagai, Shunsuke Kawamoto, Yoshikatsu Saiki, Hiroaki Shimokawa
Background -Thoracic aortic aneurysm (TAA) and dissection (TAD) are fatal diseases, which cause aortic rupture and sudden death. The small GTP-binding protein GDP dissociation stimulator (SmgGDS) is a crucial mediator of the pleiotropic effects of statins. Previous studies revealed that reduced force generation in AoSMCs causes TAA and TAD. Methods -To examine the role of SmgGDS in TAA formation, we employed an angiotensin II (AngII, 1,000 ng/min/kg, 4 weeks)-induced TAA model. Results -33% Apoe-/- SmgGDS+/- mice died suddenly due to TAA rupture, whereas there was no TAA rupture in Apoe-/- control mice...
June 19, 2018: Circulation
https://www.readbyqxmd.com/read/29916853/onabotulinumtoxin-a-injections-into-the-salivary-glands-for-spinal-muscle-atrophy-type-i-a-prospective-case-series-of-four-patients
#8
Hannah Shoval, Esther Antelis, Andrew Hillman, Xiaofang Wei, Patricia Tan, Ruth Alejandro, Heakyung Kim
OBJECTIVE: To investigate the safety and efficacy of Onabotulinum Toxin-A (BTX-A) injection to the salivary glands under ultrasound guidance for the treatment of sialorrhea in patients with spinal muscular atrophy type I (SMA I). DESIGN: Prospective case series with four patients with SMA I who received BTX-A injection to parotid and submandibular glands for sialorrhea as part of clinical care. All four patients received validated surveys for measuring drooling, including objective measures of number of bib changes, and number of mouth wipes before injection and 4-6 weeks after injection...
June 18, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29916265/the-oncolytic-adenovirus-xvir-n-31-as-a-novel-therapy-in-muscle-invasive-bladder-cancer
#9
Eva Lichtenegger, Florestan Koll, Helena Haas, Klaus Mantwill, Klaus-Peter Janssen, Melanie Laschinger, Jürgen Gschwend, Katja Steiger, Peter Black, Igor Moskalev, Roman Nawroth, Per Sonne Holm
Muscle-invasive bladder cancer represents approximately 25% of patients diagnosed with bladder cancer and carries a significant risk of death. Oncolytic viruses (OV) are novel antitumor agents with the ability to selectively replicate and lyse tumor cells while sparing healthy tissue. Thus, we explored the efficiency of the oncolytic, YB-1 selective adenovirus XVir-N-31 in vitro and in an orthotopic mouse model for bladder cancer by intramural injection under ultrasound guidance. We demonstrated that XVir-N-31 replicates in bladder cancer cells and induced a stronger immunogenic cell death than adenovirus wildtype by facilitating enhanced release of HMGB1 and exosomal Hsp70...
June 19, 2018: Human Gene Therapy
https://www.readbyqxmd.com/read/29913913/somatosensory-and-trophic-findings-in-the-referred-pain-area-in-patients-with-kidney-stone-disease
#10
Katja Venborg Pedersen, Asbjørn Mohr Drewes, Ole Graumann, Susanne Sloth Osther, Anne Estrup Olesen, Lars Arendt-Nielsen, Palle Jørn Sloth Osther
Background and purpose Visceral and somatic afferents activate the same neuronal structures in the central nervous system. Assessing somatosensory function and trophic changes in the referred pain area may therefore indirectly increase information on mechanisms involved in painful visceral diseases. The aim of this study was to evaluate the sensory and trophic changes in the flank corresponding to the referred pain area in patients with kidney stone disease. Methods A total of 24 patients with unilateral pain-causing kidney stone disease were studied before and after endoscopic percutaneous kidney stone surgery...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913629/new-objective-findings-after-whiplash-injuries-high-blood-flow-in-painful-cervical-soft-tissue-an-ultrasound-pilot-study
#11
Hatem Kalawy, Britt-Marie Stålnacke, Martin Fahlström, Lars Öhberg, Felix Linetsky, Håkan Alfredson
Background The presence of high blood flow in the structurally abnormal and painful regions of tendinosis, but not in the normal pain-free tendons, was recently confirmed by colour Doppler (CD) ultrasound (US). Biopsies from the regions with high blood flow demonstrated the presence of sympathetic and sensitive nerve fibres juxtapositioned to neovessels. Grey-scale US and CD are reliable methods used to evaluate structural homogeneity, thickness, and blood flow in the peripheral tendons. The aim of this study was to utilize CD to qualitatively evaluate for the presence of abnormal high blood flow in paravertebral tissues after whiplash injuries in patients with chronic neck pain...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29912727/ultrasound-imaging-for-sarcopenia-spasticity-and-painful-muscle-syndromes
#12
Levent Özçakar, Ayşe Merve Ata, Bayram Kaymak, Murat Kara, Dinesh Kumbhare
PURPOSE OF REVIEW: On the basis of its various advantages and the relevant awareness of physicians, ultrasound imaging has overwhelmingly taken its place in the scientific arena. This is true both from the side of daily clinical applications and also from the side of research. Yet, ultrasound provides real-time (diagnostic) imaging and (interventional) guidance for a wide spectrum of muscle disorders. In this regard, this review aims to discuss the potential/actual utility of ultrasound imaging in particular muscle disorders, that is, sarcopenia, spasticity and fibromyalgia/myofascial pain syndrome...
June 15, 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29912568/changes-in-muscle-thickness-across-positions-on-ultrasound-imaging-in-participants-with-or-without-a-history-of-low-back-pain
#13
Mark Sutherlin, Matthew Gage, Colby Mangum, Jay Hertel, Shawn Russell, Susan A Saliba, Joseph M Hart
CONTEXT:   Injury-prediction models have identified trunk muscle function as an identifiable factor for future injury. A history of low back pain (HxLBP) may also place athletes at increased risk for future low back pain. Reduced muscle thickness of the lumbar multifidus (LM) and transversus abdominis (TrA) has been reported among populations with clinical low back pain via ultrasound imaging in multiple positions. However, the roles of the LM and TrA in a more functional cohort and for injury prediction are still unknown...
June 18, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29910341/neuromuscular-adaptations-following-training-and-protein-supplementation-in-a-group-of-trained-weightlifters
#14
Christopher Taber, Kevin Carroll, Brad DeWeese, Kimitake Sato, Charles Stuart, Mary Howell, Kenton Hall, Caleb Bazyler, Michael Stone
The purpose of this study was to examine the effects of a recovery supplement compared with a placebo on muscle morphology in trained weightlifters. Vastus lateralis and muscle fiber cross sectional area of type I and type II fibers were compared between groups using a series of 2 × 2 (group × time) repeated measure ANOVAs. Both groups on average improved cross-sectional area of the vastus lateralis, type I and type II muscle fibers from pre-to-post but individual response varied within both groups...
April 19, 2018: Sports
https://www.readbyqxmd.com/read/29910305/the-three-month-effects-of-a-ketogenic-diet-on-body-composition-blood-parameters-and-performance-metrics-in-crossfit-trainees-a-pilot-study
#15
Wesley C Kephart, Coree D Pledge, Paul A Roberson, Petey W Mumford, Matthew A Romero, Christopher B Mobley, Jeffrey S Martin, Kaelin C Young, Ryan P Lowery, Jacob M Wilson, Kevin W Huggins, Michael D Roberts
Adopting low carbohydrate, ketogenic diets remains a controversial issue for individuals who resistance train given that this form of dieting has been speculated to reduce skeletal muscle glycogen levels and stifle muscle anabolism. We sought to characterize the effects of a 12-week ketogenic diet (KD) on body composition, metabolic, and performance parameters in participants who trained recreationally at a local CrossFit facility. Twelve participants (nine males and three females, 31 ± 2 years of age, 80...
January 9, 2018: Sports (Basel)
https://www.readbyqxmd.com/read/29909101/lipoprotein-apheresis-acutely-reverses-coronary-microvascular-dysfunction-in-patients-with-severe-hypercholesterolemia
#16
Melinda D Wu, Federico Moccetti, Eran Brown, Brian P Davidson, Tamara Atkinson, J Todd Belcik, George Giraud, P Barton Duell, Sergio Fazio, Hagai Tavori, Sotirios Tsimikas, Jonathan R Lindner
OBJECTIVES: The study evaluated whether lipoprotein apheresis produces immediate changes in resting perfusion in subjects with severe hypercholesterolemia, and whether there is a difference in the response between peripheral and coronary microcirculations. BACKGROUND: Lipoprotein apheresis is used in patients with severe hypercholesterolemia to reduce plasma levels of low-density lipoprotein cholesterol. METHODS: Quantitative contrast-enhanced ultrasound perfusion imaging of the myocardium at rest and skeletal muscle at rest and during calibrated contractile exercise was performed before and immediately after lipoprotein apheresis in 8 subjects with severe hypercholesterolemia, 7 of whom had a diagnosis of familial hypercholesterolemia...
June 9, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29908601/ultrasound-or-microwave-vacuum-thawing-of-red-seabream-pagrus-major-fillets
#17
Luyun Cai, Minjie Cao, Ailing Cao, Joe Regenstein, Jianrong Li, Rongfa Guan
Ultrasound assisted vacuum thawing (UVT) or microwave vacuum thawing (MVT) with red seabream fillets were compared to fresh, chill storage thawing, vacuum thawing, microwave thawing and ultrasound thawing. The thermal stability and gelation properties were studied with DSC and dynamic rheology, respectively. Raman spectra before and after H/D isotope exchange and intrinsic fluorescence were used to measure protein secondary and tertiary structure. Low-field NMR was done to measure water migration. The two thawing techniques both retained actin thermal stability and generally retained more stable tertiary structures than the other thawing methods...
October 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29908102/sex-related-differences-in-muscle-size-explained-by-amplitudes-of-higher-threshold-motor-unit-action-potentials-and-muscle-fiber-typing
#18
Michael A Trevino, Adam J Sterczala, Jonathan D Miller, Mandy E Wray, Hannah L Dimmick, Anthony B Ciccone, Joseph P Weir, Philip M Gallagher, Andrew C Fry, Trent J Herda
AIM: To investigate the relationships between motor unit action potential amplitudes (MUAPAMP ), muscle cross-sectional area (mCSA) and composition (mEI), percent myosin heavy chain (%MHC) areas, and sex in the vastus lateralis (VL). METHODS: Ten males and 10 females performed a submaximal isometric trapezoid muscle action that included a linearly increasing, steady torque at 40% maximal voluntary contraction, and linearly decreasing segments. Surface electromyographic decomposition techniques were utilized to determine MUAPAMPS in relation to recruitment thresholds (RT)...
June 16, 2018: Acta Physiologica
https://www.readbyqxmd.com/read/29906277/can-ultrasound-measures-of-intrinsic-foot-muscles-and-plantar-soft-tissues-predict-future-diabetes-related-foot-disease-a-systematic-review
#19
Troy Morrison, Sara Jones, Ryan S Causby, Kerry Thoirs
INTRODUCTION: Diabetes mellitus (DM) is associated with hyperglycaemia and advanced glycosylation end-products. In the foot, the consequences of chronic or uncontrolled diabetes are micro and macrovascular disease, neuropathy, reduced joint mobility and structural and soft tissue changes that increase the risk of ulcer development and amputation. Diabetes foot assessment currently includes a comprehensive history, neurological and vascular assessments and examination focussed on dermatological and musculoskeletal abnormalities...
2018: PloS One
https://www.readbyqxmd.com/read/29903838/the-slack-test-does-not-assess-maximal-shortening-velocity-of-muscle-fascicle-in-human
#20
Robin Hager, Sylvain Dorel, Antoine Nordez, Giuseppe Rabita, Antoine Couturier, Hugo Hauraix, Jacques Duchateau, Gaël Guilhem
The application of a series of extremely high accelerative motor-driven quick releases while muscles contract isometrically (i.e. slack test) has been proposed to assess unloaded velocity in human muscle. This study aimed to measure gastrocnemius medialis fascicle (VF ) and tendinous tissues shortening velocity during motor-driven quick releases performed at various activation levels to assess the applicability of the slack test method in human. Maximal fascicle shortening velocity and joint velocity recorded during quick releases and during fast contraction without external load (ballistic condition) were compared...
June 14, 2018: Journal of Experimental Biology
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