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https://www.readbyqxmd.com/read/28427440/hypoglycemia-identified-by-a-continuous-glucose-monitoring-system-in-a-second-trimester-pregnant-woman-with-insulinoma-a-case-report
#1
Marjeta Tomazic, Andrej Janez, Maja Ravnik Oblak
BACKGROUND: Insulinoma associated with pregnancy is a very rare condition and can be difficult to diagnose. Here, we present an interesting case of insulinoma occurring during pregnancy with special attention paid to the use of a continuous glucose monitoring system to detect hypoglycemia. CASE PRESENTATION: A 36-year-old white woman in the second trimester of pregnancy presented with recurrent episodes of hypoglycemia associated with neuroglycopenic symptoms. The use of a continuous glucose monitoring system confirmed hypoglycemia...
April 21, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28427231/histopathologic-tumor-invasion-of-superior-mesenteric-vein-portal-vein-is-a-poor-prognostic-indicator-in-patients-with-pancreatic-ductal-adenocarcinoma-results-from-a-systematic-review-and-meta-analysis
#2
Ailin Song, Farong Liu, Lupeng Wu, Xiaoying Si, Yanming Zhou
BACKGROUND: The impact of histopathologic tumor invasion of the superior mesenteric vein (SMV)/portal vein (PV) on prognosis in patients with pancreatic ductal adenocarcinoma (PDAC) after pancreatectomy remains controversial. A meta-analysis was performed to assess this issue. RESULTS: Eighteen observational studies comprising 5242 patients were eligible, of whom 2199 (41.9%) patients received SMV/PV resection. Histopathologic tumor invasion was detected in 1218 (58...
March 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28424909/comparison-of-clinical-outcomes-and-quality-of-life-between-laparoscopic-and-open-central-pancreatectomy-with-pancreaticojejunostomy
#3
Ren-Chao Zhang, Bin Zhang, Yi-Ping Mou, Xiao-Wu Xu, Yu-Cheng Zhou, Chao-Jie Huang, Jia-Yu Zhou, Wei-Wei Jin, Chao Lu
BACKGROUND: The studies comparing laparoscopic and open central pancreatectomy with pancreaticojejunostomy are limited. This study aimed to compare clinical outcomes and quality of life of patients undergoing laparoscopic and open central pancreatectomy with pancreaticojejunostomy. METHODS: Between December 1997 and December 2015, patients who underwent central pancreatectomy with pancreaticojejunostomy were reviewed. Patients were divided into 2 groups as laparoscopic central pancreatectomy (LCP) and open central pancreatectomy (OCP)...
April 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28418366/-the-role-of-3d-ct-in-surgery-for-pancreatic-ductal-adenocarcinoma-post-processing-and-tissue-volume-calculation
#4
Ya I Nerestyuk, G G Karmazanovsky, V A Kubyshkin, A G Krieger, A V Khairieva
AIM: To define the indications for pancreatoduodenectomy using 3D CT-imaging, to calculate the volume of damaged and intact tissues and to determine type of surgery depending on severity of disease in case of ductal pancreatic adenocarcinoma. MATERIAL AND METHODS: Retrospective analysis of CT-scans of 30 patients with ductal pancreatic adenocarcinoma was performed. In groups 1 and 2 by 15 patients total pancreatectomy and pancreatoduodenectomy were made respectively...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28415940/thymoma-metastatic-to-liver-and-pancreas-case-report-and-review-of-the-literature
#5
Nicola Passuello, Gioia Pozza, Stella Blandamura, Michele Valmasoni, Cosimo Sperti
A 71-year-old man presented with a thymic mass involving the superior vena cava. A mediastinoscopical biopsy initially suggested a diagnosis of type A thymoma. After neoadjuvant chemotherapy, the patient underwent en-bloc thymectomy and vascular resection for a pathology-confirmed type B3 thymoma involving the superior vena cava, the left brachiocephalic vein and the distal part of the right brachiocephalic vein. Adjuvant radiotherapy was administered. Two years after the primary surgery, abdominal computed tomography (CT) and whole body fluorodeoxyglucose (18-FDG) positron emission tomography (PET) scans showed a single hepatic lesion that was treated with wedge liver resection...
April 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28414116/the-largest-european-single-center-experience-300-laparoscopic-pancreatic-resections
#6
Safi Dokmak, Fadhel Samir Ftériche, Béatrice Aussilhou, Philippe Lévy, Philippe Ruszniewski, Jérome Cros, Marie Pierre Vullierme, Linda Khoy Ear, Jacques Belghiti, Alain Sauvanet
BACKGROUND: Although laparoscopic pancreatic resection (LPR) has become a routine, large single center series are still lacking. Our aim was to analyze the results of a large European single center series of LPR. STUDY DESIGN: Between January 2008 and September 2015, 300 LPR were performed and studied prospectively including 165 (55%) distal pancreatectomies, 68 (23%) pancreatoduodenectomies (PD), 30 (10%) enucleations, 35 (11%) central pancreatectomies and 2 (1%) total pancreatectomies...
April 13, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28414114/why-do-long-distance-travelers-have-improved-pancreatectomy-outcomes
#7
Manila Jindal, Chaoyi Zheng, Humair S Quadri, Chukwuemeka U Ihemelandu, Young K Hong, Andrew K Smith, Vikas Dudeja, Nawar M Shara, Lynt B Johnson, Waddah B Al-Refaie
BACKGROUND: Centralization of complex surgical care has led patients to travel longer distances. Emerging evidence suggested a negative association between increased travel distance and mortality after pancreatectomy. However, the reason behind this association remains largely unknown. We sought to unravel the relationships among travel distance, receiving pancreatectomy at high volume hospitals (HVH), delayed surgery, and operative outcomes. STUDY DESIGN: We identified 44,476 patients who underwent pancreatectomy for neoplasms between 2004 and 2013 at the reporting facility from the National Cancer Data Base...
April 13, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28413390/a-serous-cystic-neoplasm-of-the-pancreas-coexisting-with-high-grade-pancreatic-intraepithelial-neoplasia-mimicking-an-intraepithelial-papillary-mucinous-neoplasm-a-case-report
#8
Aya Kawanishi, Kenichi Hirabayashi, Hirotaka Kono, Yumi Takanashi, Atsuko Hadano, Yohei Kawashima, Masami Ogawa, Yoshiaki Kawaguchi, Misuzu Yamada, Toshio Nakagohri, Naoya Nakamura, Tetsuya Mine
Serous cystic neoplasms of the pancreas are rare exocrine pancreatic neoplasms, most of which are benign and do not communicate with the pancreatic duct. Pancreatic intraepithelial neoplasm (PanIN) is considered a precursor of ductal adenocarcinoma that is microscopically recognized in pancreatic ducts. A 67-year-old Japanese woman presented with a 10-mm multilocular cystic lesion at the pancreatic body. Magnetic resonance pancreatography showed stenosis of the main pancreatic duct at the pancreatic body and dilatation of the distal side of the main pancreatic duct...
January 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28411019/comparison-of-surgical-outcomes-of-three-different-stump-closure-techniques-during-distal-pancreatectomy
#9
Ilhan Karabicak, Sohei Satoi, Hiroaki Yanagimoto, Tomohisa Yamamoto, So Yamaki, Hisashi Kosaka, Satoshi Hirooka, Masaya Kotsuka, Taku Michiura, Kentaro Inoue, Yoichi Matsui, Masanori Kon
BACKGROUND: To find the appropriate method of pancreatic transection during distal pancreatectomy (DP), we retrospectively compared post-operative complications including postoperative pancreatic fistula (POPF) according to the different types of pancreatic transection. METHODS: This study included 169 patients who underwent pancreatic transection using an ultrasonic activated device (USAD) with transfixion of the pancreatic duct (DP-TF group, n = 89), USAD followed by pancreaticogastrostomy (DP-PG group, n = 44), and a reinforced linear tristapler (DP-ST, n = 36)...
April 8, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28410913/superior-mesenteric-artery-sma-resection-during-pancreatectomy-for-malignant-disease-of-the-pancreas-a%C3%A2-systematic-review
#10
REVIEW
Santhalingam Jegatheeswaran, Minas Baltatzis, Saurabh Jamdar, Ajith K Siriwardena
BACKGROUND: Resection of the superior mesenteric artery (SMA) during pancreatectomy is performed infrequently and is undertaken with the aim of removing non-metastatic locally advanced pancreatic tumours. SMA resection reports also encompass resection of other visceral vessels. The consequences of resection of these different arteries are not necessarily equivalent. This is a focused systematic review of the outcome of SMA resection during pancreatectomy for cancer. METHODS: A computerized search of the English language literature was undertaken for the period 1st January 2000 through 30th April 2016...
April 11, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28409377/laparoscopic-radical-antegrade-modular-pancreatosplenectomy-for-left-sided-pancreatic-cancer-using-the-ligament-of-treitz-approach
#11
Yusuke Ome, Kazuki Hashida, Mitsuru Yokota, Yoshio Nagahisa, Okabe Michio, Kazuyuki Kawamoto
BACKGROUND: Laparoscopic distal pancreatectomy (Lap-DP) for benign lesions or those with low malignant potential has been proven safe and effective, and its performance is now widespread [1-3]. Lap-DP for left-sided pancreatic cancer (PC) is also being increasingly performed. According to some reports, Lap-DP has superior short-term outcomes (blood loss, postoperative hospital stay) and comparable oncological outcomes and overall survival with those of open distal pancreatectomy (Op-DP) [4-6]...
April 13, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28407704/delayed-epidural-mucin-collection-after-surgery-for-spinal-metastatic-pancreatic-adenocarcinoma
#12
Dong Ha Kim, Dong Hwan Kim, Hwan Soo Kim, Kyoung Hyup Nam, Byung Kwan Choi, In Ho Han
A rare case of delayed large epidural mucin collection causing neurologic deficit after surgery for metastatic pancreatic cancer is reported. A 65-year-old man presented with intractable upper-thoracic back pain radiating to the chest and gait disturbance. He had a history of subtotal pancreatectomy due to intraductal papillary mucinous neoplasm (IPMN) of the pancreas and concurrent chemotherapy. Eight months after pancreatectomy, multiple thoracic spinal metastasis was diagnosed with routine up positron emission tomography-computed tomography...
March 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/28406793/population-level-incidence-and-predictors-of-surgically-induced-diabetes-and-exocrine-insufficiency-after-partial-pancreatic-resection
#13
Irmina A Elliott, Irene Epelboym, Megan Winner, John D Allendorf, Philip I Haigh
CONTEXT: Endocrine and exocrine insufficiency after partial pancreatectomy affect quality of life, cardiovascular health, and nutritional status. However, their incidence and predictors are unknown. OBJECTIVE: To identify the incidence and predictors of new-onset diabetes and exocrine insufficiency after partial pancreatectomy. DESIGN: We retrospectively reviewed 1165 cases of partial pancreatectomy, performed from 1998 to 2010, from a large population-based database...
2017: Permanente Journal
https://www.readbyqxmd.com/read/28400087/minimally-invasive-hepatopancreatobiliary-surgery-in-north-america-an-acs-nsqip-analysis-of-predictors-of-conversion-for-laparoscopic-and-robotic-pancreatectomy-and-hepatectomy
#14
Amer H Zureikat, Jeffrey Borrebach, Henry A Pitt, Douglas Mcgill, Melissa E Hogg, Vanessa Thompson, David J Bentrem, Bruce L Hall, Herbert J Zeh
BACKGROUND: Procedural conversion rates represent an important aspect of the feasibility of minimally invasive surgical (MIS) approaches. This study aimed to outline the rates and predictors of procedural completion/conversion for MIS hepatectomy and pancreatectomy. METHODS: All 2014 ACS-NSQIP laparoscopic and robotic hepatectomy and pancreatectomy procedures were identified and grouped into pure, open assist, or unplanned conversion to open. Risk adjusted multinomial logistic regression models were generated with completion (Pure) set as the primary outcome...
April 8, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28398495/a-histological-study-of-fulminant-type-1-diabetes-mellitus-related-to-human-cytomegalovirus-reactivation
#15
Sho Yoneda, Akihisa Imagawa, Kenji Fukui, Sae Uno, Junji Kozawa, Makoto Sakai, Toshiki Yumioka, Hiromi Iwahashi, Iichiro Shimomura
Context: Fulminant type 1 diabetes mellitus (T1DM) is thought to be partly caused by virus infection. Objective: This study investigated the mechanism of β cell destruction in fulminant T1DM after drug-induced hypersensitivity syndrome (DIHS). Methods: We determined the localization of viruses of human cytomegalovirus (HCMV), human herpesvirus 6 (HHV-6) and Epstein-Barr virus (EBV), and the expression of interferon regulatory factor 3 (IRF3) and viral receptors of Z DNA binding protein 1 (ZBP1) and retinoic acid-inducible gene I (RIG-I), together with inflammatory cells by immunohistochemistry of pancreas from an autopsy fulminant T1DM patient with DIHS or seven subjects with normal glucose tolerance who underwent pancreatectomy...
April 10, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28397026/fistulojejunostomy-versus-distal-pancreatectomy-for-the-management-of-the-disconnected-pancreas-remnant-following-necrotizing-pancreatitis
#16
Vikrom K Dhar, Jeffrey M Sutton, Brent T Xia, Nick C Levinsky, Gregory C Wilson, Milton Smith, Kyuran A Choe, Jonathan Moulton, Doan Vu, Ross Ristagno, Jeffrey J Sussman, Michael J Edwards, Daniel E Abbott, Syed A Ahmad
BACKGROUND: A disconnected distal pancreas (DDP) remnant is a morbid sequela of necrotizing pancreatitis. Definitive surgical management can be accomplished by either fistulojejunostomy (FJ) or distal pancreatectomy (DP). It is unclear which operative approach is superior with regard to short- and long-term outcomes. METHODS: Between 2002 and 2014, patients undergoing either FJ or DP for DDP were retrospectively identified at a center specializing in pancreatic diseases...
April 10, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28396721/resection-of-complex-pancreatic-injuries-benchmarking-postoperative-complications-using-the-accordion-classification
#17
Jake E Krige, Eduard Jonas, Sandie R Thomson, Urda K Kotze, Mashiko Setshedi, Pradeep H Navsaria, Andrew J Nicol
AIM: To benchmark severity of complications using the Accordion Severity Grading System (ASGS) in patients undergoing operation for severe pancreatic injuries. METHODS: A prospective institutional database of 461 patients with pancreatic injuries treated from 1990 to 2015 was reviewed. One hundred and thirty patients with AAST grade 3, 4 or 5 pancreatic injuries underwent resection (pancreatoduodenectomy, n = 20, distal pancreatectomy, n = 110), including 30 who had an initial damage control laparotomy (DCL) and later definitive surgery...
March 27, 2017: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28394870/postoperative-morbidity-after-radical-resection-of-primary-retroperitoneal-sarcoma-a-report-from-the-transatlantic-rps-working-group
#18
Andrea J MacNeill, Alessandro Gronchi, Rosalba Miceli, Sylvie Bonvalot, Carol J Swallow, Peter Hohenberger, Frits Van Coevorden, Piotr Rutkowski, Dario Callegaro, Andrew J Hayes, Charles Honoré, Mark Fairweather, Amanda Cannell, Jens Jakob, Rick L Haas, Milena Szacht, Marco Fiore, Paolo G Casali, Raphael E Pollock, Francesco Barretta, Chandrajit P Raut, Dirk C Strauss
OBJECTIVE: To investigate the safety of radical resection for retroperitoneal sarcoma (RPS). BACKGROUND: The surgical management of RPS frequently involves complex multivisceral resection. Improved oncologic outcomes have been demonstrated with this approach compared to marginal excision, but the safety of radical resection has not been shown in a large study population. METHODS: The Transatlantic Retroperitoneal Sarcoma Working Group (TARPSWG) is an international collaborative of sarcoma centers...
April 7, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28389802/the-yonsei-criteria-as-a-clinically-detectable-parameter-for-excellent-prognosis-in-resected-left-sided-pancreatic-cancer-outcomes-of-a-propensity-score-matched-analysis
#19
Sung Hwan Lee, Ho Kyoung Hwang, Chang Moo Kang, Woo Jung Lee
BACKGROUND: This study aimed to identify that Yonsei criteria (YC) can be regarded as a preoperative clinical parameter to predict biological behavior of the left-sided pancreatic cancer. METHODS: Between June 2007 and December 2014, 135 patients who underwent minimally invasive (MIS) or open distal pancreatectomy for left-sided pancreatic cancer were enrolled in this study consecutively. Perioperative short-term and long-term oncologic outcomes were analyzed according to the YC retrospectively...
April 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28388963/minimally-invasive-versus-open-distal-pancreatectomy-leopard-study-protocol-for-a-randomized-controlled-trial
#20
Thijs de Rooij, Jony van Hilst, Jantien A Vogel, Hjalmar C van Santvoort, Marieke T de Boer, Djamila Boerma, Peter B van den Boezem, Bert A Bonsing, Koop Bosscha, Peter-Paul Coene, Freek Daams, Ronald M van Dam, Marcel G Dijkgraaf, Casper H van Eijck, Sebastiaan Festen, Michael F Gerhards, Bas Groot Koerkamp, Jeroen Hagendoorn, Erwin van der Harst, Ignace H de Hingh, Cees H Dejong, Geert Kazemier, Joost Klaase, Ruben H de Kleine, Cornelis J van Laarhoven, Daan J Lips, Misha D Luyer, I Quintus Molenaar, Vincent B Nieuwenhuijs, Gijs A Patijn, Daphne Roos, Joris J Scheepers, George P van der Schelling, Pascal Steenvoorde, Rutger-Jan Swijnenburg, Jan H Wijsman, Moh'd Abu Hilal, Olivier R Busch, Marc G Besselink
BACKGROUND: Observational cohort studies have suggested that minimally invasive distal pancreatectomy (MIDP) is associated with better short-term outcomes compared with open distal pancreatectomy (ODP), such as less intraoperative blood loss, lower morbidity, shorter length of hospital stay, and reduced total costs. Confounding by indication has probably influenced these findings, given that case-matched studies failed to confirm the superiority of MIDP. This accentuates the need for multicenter randomized controlled trials, which are currently lacking...
April 8, 2017: Trials
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