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https://www.readbyqxmd.com/read/29768499/a-fixable-probe-for-visualizing-flagella-and-plasma-membranes-of-the-african-trypanosome
#1
Justin Wiedeman, Kojo Mensa-Wilmot
The protozoan Trypanosoma brucei sp. cause diseases in humans and animals. Studies of T. brucei cell biology have revealed unique features, such as major endocytic events being limited to a single region, and mitochondrial genome segregation mediated via basal bodies. Further understanding of trypanosome cell biology can be facilitated with super-resolution fluorescence microscopy. Lack of a plasma membrane probe for fixed trypanosomes remains a persistent problem in need of a working solution. Herein, we report protocols developed using mCLING in super-resolution structured illumination fluorescence microscopy (SR-SIM)...
2018: PloS One
https://www.readbyqxmd.com/read/29714255/influence-investigation-on-ranging-performance-for-range-gated-geiger-mode-avalanche-photodiode-ladar
#2
Xin Zhou, Jianfeng Sun, Peng Jiang, Di Liu, Qi Wang
The ranging performance for Geiger-mode avalanche photodiode (Gm-APD) laser detection and ranging (ladar) is mainly evaluated by range accuracy and precision; although Gm-APD ladar can evaluate the ranging performance of the exact position, it is not helpful to comprehensively evaluate the influence on the ranging of each parameter in the whole gate. Due to the target echo's stochastic trigger making the delay adjustment inaccurate, the position of the echo in the gate is stochastic in the actual detection process, so the theoretical calculation may not be able to make ladar ranging performance clear...
April 1, 2018: Applied Optics
https://www.readbyqxmd.com/read/29670028/a-sparse-driven-anti-velocity-deception-jamming-strategy-based-on-pulse-doppler-radar-with-random-pulse-initial-phases
#3
Zhen Liu, Jinping Sui, Zhenhua Wei, Xiang Li
This paper focuses on developing an anti-velocity jamming strategy that enhances the ability of a pulse-Doppler (PD) radar to detect moving targets in the presence of translational and/or micro motion velocity jamming generated by the digital radio frequency memory (DRFM) repeat jammers. The strategy adopts random pulse initial phase (RPIP) pulses as its transmitted signal and thus gets DRFM jammers not adaptable to the randomness of initial phase of the transmitted pulses in the pulse repetition interval (PRI) domain...
April 18, 2018: Sensors
https://www.readbyqxmd.com/read/29642508/eccm-scheme-against-interrupted-sampling-repeater-jammer-based-on-parameter-adjusted-waveform-design
#4
Zhenhua Wei, Zhen Liu, Bo Peng, Rui Shen
Interrupted sampling repeater jamming (ISRJ) is an effective way of deceiving coherent radar sensors, especially for linear frequency modulated (LFM) radar. In this paper, for a simplified scenario with a single jammer, we propose a dynamic electronic counter-counter measure (ECCM) scheme based on jammer parameter estimation and transmitted signal design. Firstly, the LFM waveform is transmitted to estimate the main jamming parameters by investigating the discontinuousness of the ISRJ's time-frequency (TF) characteristics...
April 8, 2018: Sensors
https://www.readbyqxmd.com/read/29611504/albendazole-treatment-improves-work-capacity-in-women-smallholder-farmers-infected-with-hookworm-a-double-blind-randomized-control-trial
#5
Margaret Salmon, Christian Salmon, Maurice Masoda, Jean-Maurice Salumu, Carmine Bozzi, Phil Nieburg, Lisa M Harrison, Debbie Humphries, Naomi Abaca Uvon, Sarah K Wendel, Clint Trout, Michael Cappello
An estimated 4.7 billion people live in regions exposed to soil-transmitted helminths, intestinal parasites that have significant impacts on the health of women smallholder farmers. The goal of this trial was to determine whether treatment with albendazole impacts the work capacity of these farmers. This is a prospective double-blind, randomized effectiveness trial. Participants ( N = 250) were randomly selected from safe motherhood groups in the Democratic Republic of Congo. Prevalence/intensity of hookworm infection, hemoglobin, and demographics was obtained...
April 2, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29603381/high-resolution-whole-brain-diffusion-mri-at-7t-using-radiofrequency-parallel-transmission
#6
Xiaoping Wu, Edward J Auerbach, An T Vu, Steen Moeller, Christophe Lenglet, Sebastian Schmitter, Pierre-François Van de Moortele, Essa Yacoub, Kâmil Uğurbil
PURPOSE: Investigating the utility of RF parallel transmission (pTx) for Human Connectome Project (HCP)-style whole-brain diffusion MRI (dMRI) data at 7 Tesla (7T). METHODS: Healthy subjects were scanned in pTx and single-transmit (1Tx) modes. Multiband (MB), single-spoke pTx pulses were designed to image sagittal slices. HCP-style dMRI data (i.e., 1.05-mm resolutions, MB2, b-values = 1000/2000 s/mm2 , 286 images and 40-min scan) and data with higher accelerations (MB3 and MB4) were acquired with pTx...
March 30, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29558432/a-low-cost-tracking-system-for-running-race-applications-based-on-bluetooth-low-energy-technology
#7
David Perez-Diaz-de-Cerio, Ángela Hernández-Solana, Antonio Valdovinos, Jose Luis Valenzuela
Timing points used in running races and other competition events are generally based on radio-frequency identification (RFID) technology. Athletes' times are calculated via passive RFID tags and reader kits. Specifically, the reader infrastructure needed is complex and requires the deployment of a mat or ramps which hide the receiver antennae under them. Moreover, with the employed tags, it is not possible to transmit additional and dynamic information such as pulse or oximetry monitoring, alarms, etc. In this paper we present a system based on two low complex schemes allowed in Bluetooth Low Energy (BLE): the non-connectable undirected advertisement process and a modified version of scannable undirected advertisement process using the new capabilities present in Bluetooth 5...
March 20, 2018: Sensors
https://www.readbyqxmd.com/read/29535694/characterization-of-resistance-patterns-and-detection-of-apramycin-resistance-genes-in-escherichia-coli-isolated-from-chicken-feces-and-houseflies-after-apramycin-administration
#8
Anyun Zhang, Yunxia Li, Zhongbin Guan, Hongmei Tuo, Dan Liu, Yanxian Yang, Changwen Xu, Changwei Lei, Hongning Wang
The aim of this study was to evaluate the influence of apramycin administration on the development of antibiotic resistance in Escherichia coli ( E. coli ) strains isolated from chicken feces and houseflies under field conditions. Chickens in the medicated group ( n = 25,000) were given successive prophylactic doses (0.5 mg/l) of apramycin in their drinking water from Days 1 to 5, while no antibiotics were added to the un-medicated groups drinking water ( n = 25,000). Over 40 days, a total of 1170 E. coli strains were isolated from fecal samples obtained from medicated and un-medicated chickens and houseflies from the same chicken farm...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29524090/nocturnal-blood-pressure-fluctuation-and-associated-influential-factors-in-severe-obstructive-sleep-apnea-patients-with-hypertension
#9
Jing Xu, Ning Ding, Xilong Zhang, Nana Wang, Bing Sun, Rong Zhang, Xiaochen Xie, Zongren Wan, Yanli Gu, Shan Zhang, Yongqing Hong, Mao Huang, Zili Meng
PURPOSE: Obstructive sleep apnea syndrome (OSAS) can induce dramatic blood pressure (BP) fluctuations during sleep and it can be associated with hypertension. We investigated the properties and associated influential factors of BP fluctuation in severe OSAS with and without hypertension. METHODS: Two hundred one severe OSAS subjects were divided into hypertensive and normotensive groups. BP was continuously monitored via measurement of pulse transmit time (PTT)...
March 9, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29522402/safe-local-navigation-for-visually-impaired-users-with-a-time-of-flight-and-haptic-feedback-device
#10
Robert K Katzschmann, Brandon Araki, Daniela Rus
This paper presents ALVU (Array of Lidars and Vibrotactile Units), a contactless, intuitive, hands-free, and discreet wearable device that allows visually impaired users to detect low- and high-hanging obstacles, as well as physical boundaries in their immediate environment. The solution allows for safe local navigation in both confined and open spaces by enabling the user to distinguish free space from obstacles. The device presented is composed of two parts: a sensor belt and a haptic strap. The sensor belt is an array of time-of-flight distance sensors worn around the front of a user's waist, and the pulses of infrared light provide reliable and accurate measurements of the distances between the user and surrounding obstacles or surfaces...
March 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29476551/whole-brain-3d-flair-at-7t-using-direct-signal-control
#11
Arian Beqiri, Hans Hoogduin, Alessandro Sbrizzi, Joseph V Hajnal, Shaihan J Malik
PURPOSE: Image quality obtained for brain imaging at 7T can be hampered by inhomogeneities in the static magnetic field, B0 , and the RF electromagnetic field, B1 . In imaging sequences such as fluid-attenuated inversion recovery (FLAIR), which is used to assess neurological disorders, these inhomogeneities cause spatial variations in signal that can reduce clinical efficacy. In this work, we aim to correct for signal inhomogeneities to ensure whole-brain coverage with 3D FLAIR at 7T...
February 24, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29475318/secure-communications-using-nonlinear-silicon-photonic-keys
#12
Brian C Grubel, Bryan T Bosworth, Michael R Kossey, A Brinton Cooper, Mark A Foster, Amy C Foster
We present a secure communication system constructed using pairs of nonlinear photonic physical unclonable functions (PUFs) that harness physical chaos in integrated silicon micro-cavities. Compared to a large, electronically stored one-time pad, our method provisions large amounts of information within the intrinsically complex nanostructure of the micro-cavities. By probing a micro-cavity with a rapid sequence of spectrally-encoded ultrafast optical pulses and measuring the lightwave responses, we experimentally demonstrate the ability to extract 2...
February 19, 2018: Optics Express
https://www.readbyqxmd.com/read/29457587/power-cavitation-guided-blood-brain-barrier-opening-with-focused-ultrasound-and-microbubbles
#13
M T Burgess, I Apostolakis, E E Konofagou
Image-guided monitoring of microbubble-based focused ultrasound (FUS) therapies relies on the accurate localization of FUS-stimulated microbubble activity (i.e. acoustic cavitation). Passive cavitation imaging with ultrasound arrays can achieve this, but with insufficient spatial resolution. In this study, we address this limitation and perform high-resolution monitoring of acoustic cavitation-mediated blood-brain barrier (BBB) opening with a new technique called power cavitation imaging. By synchronizing the FUS transmit and passive receive acquisition, high-resolution passive cavitation imaging was achieved by using delay and sum beamforming with absolute time delays...
March 15, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29424693/improved-contrast-enhanced-ultrasound-imaging-with-multiplane-wave-imaging
#14
Ping Gong, Pengfei Song, Shigao Chen
Contrast-enhanced ultrasound (CEUS) imaging has great potential for use in new ultrasound clinical applications such as myocardial perfusion imaging and abdominal lesion characterization. In CEUS imaging, contrast agents (i.e., microbubbles) are used to improve contrast between blood and tissue because of their high nonlinearity under low ultrasound pressure. However, the quality of CEUS imaging sometimes suffers from a low signal-to-noise ratio (SNR) in deeper imaging regions when a low mechanical index (MI) is used to avoid microbubble disruption, especially for imaging at off-resonance transmit frequencies...
February 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/29424032/a-self-powered-sensor-mimicking-slow-and-fast-adapting-cutaneous-mechanoreceptors
#15
Kyoung-Yong Chun, Young Jun Son, Eun-Seok Jeon, Sehan Lee, Chang-Soo Han
Highly efficient human skin systems transmit fast adaptive (FA) and slow adaptive (SA) pulses selectively or consolidatively to the brain for a variety of external stimuli. The integrated analysis of these signals determines how humans perceive external physical stimuli. Here, a self-powered mechanoreceptor sensor based on an artificial ion-channel system combined with a piezoelectric film is presented, which can simultaneously implement FA and SA pulses like human skin. This device detects stimuli with high sensitivity and broad frequency band without external power...
March 2018: Advanced Materials
https://www.readbyqxmd.com/read/29415019/modeling-convection-diffusion-reaction-systems-for-microfluidic-molecular-communications-with-surface-based-receivers-in-internet-of-bio-nano-things
#16
Murat Kuscu, Ozgur B Akan
We consider a microfluidic molecular communication (MC) system, where the concentration-encoded molecular messages are transported via fluid flow-induced convection and diffusion, and detected by a surface-based MC receiver with ligand receptors placed at the bottom of the microfluidic channel. The overall system is a convection-diffusion-reaction system that can only be solved by numerical methods, e.g., finite element analysis (FEA). However, analytical models are key for the information and communication technology (ICT), as they enable an optimisation framework to develop advanced communication techniques, such as optimum detection methods and reliable transmission schemes...
2018: PloS One
https://www.readbyqxmd.com/read/29377809/a-1-55-%C3%AE-w-bio-impedance-measurement-system-for-implantable-cardiac-pacemakers-in-0-18-%C3%AE-m-cmos
#17
Milad Zamani, Yasser Rezaeiyan, Omid Shoaei, Wouter A Serdijn
This paper presents an implantable bio-impedance measurement system for cardiac pacemakers. The fully integrated system features a low power analog front-end and pulse width modulated output. The bio-impedance readout benefits from voltage to time conversion to achieve a very low power consumption for wirelessly transmitting the data outside the body. The proposed IC is fabricated in a 0.18 μm CMOS process and is capable of measuring the bio-impedance at 2 kHz over a wide dynamic range from to with accuracy and maximum current injection while consuming just from a 1 V supply...
February 2018: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/29330080/use-of-pulsed-radiofrequency-energy-device-peak-plasmablade-in-neuromodulation-implant-revisions
#18
Ismail Ughratdar, Khandkar Ali Kawsar, Rosalind Mitchell, Richard Selway, Keyoumars Ashkan
BACKGROUND: Battery replacement or revision surgery for neuromodulation implants is conventionally performed using sharp dissection. Meticulous dissection within thick scar tissue is vital to avoid damage to surrounding lead(s), which could result in more extensive revision surgery. Traditional electrosurgery devices are contraindicated as the emitted energy can be transferred to the hardware, resulting in implant or tissue damage with severe consequent complications. OBJECTIVE: We report our experience and potential applications of a novel, pulsed monopolar radiofrequency energy device (PEAK PlasmaBlade, Medtronic PLC, Minneapolis, Minnesota, USA), which facilitates dissection around implants without the risk of damaging or transmitting energy through the system...
April 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29299250/marine-subsidies-change-short-term-foraging-activity-and-habitat-utilization-of-terrestrial-lizards
#19
Heather V Kenny, Amber N Wright, Jonah Piovia-Scott, Louie H Yang, David A Spiller, Thomas W Schoener
Resource pulses are brief periods of unusually high resource abundance. While population and community responses to resource pulses have been relatively well studied, how individual consumers respond to resource pulses has received less attention. Local consumers are often the first to respond to a resource pulse, and the form and timing of individual responses may influence how the effects of the pulse are transmitted throughout the community. Previous studies in Bahamian food webs have shown that detritivores associated with pulses of seaweed wrack provide an alternative prey source for lizards...
December 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29248794/quantitative-imaging-performance-of-frequency-tunable-capacitive-micromachined-ultrasonic-transducer-array-designed-for-intracardiac-application-phantom-study
#20
Martin Pekař, Nenad Mihajlović, Harm Belt, Alexander F Kolen, Jeannet van Rens, Frank Budzelaar, Bas Jacobs, Johan G Bosch, Hendrik J Vos, Debbie Rem-Bronneberg, Gijs van Soest, Antonius F W van der Steen
Commercially available intracardiac echo (ICE) catheters face a trade-off between viewing depth and resolution. Frequency-tunable ICE probes would offer versatility of choice between penetration or resolution imaging within a single device. In this phantom study, the imaging performance of a novel, frequency-tunable, 32-element, 1-D CMUT array integrated with front-end electronics is evaluated. Phased-array ultrasound imaging with a forward-looking CMUT probe prototype operated beyond collapse mode at voltages up to three times higher than the collapse voltage (-65 V) is demonstrated...
March 2018: Ultrasonics
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