Malcolm Hart Squires, Cecilia G Ethun, Erin E Donahue, Jennifer H Benbow, Colin J Anderson, Megan H Jagosky, Munsa Manandhar, Joshua C Patt, Jeffrey S Kneisl, Jonathan C Salo, Joshua S Hill, William Ahrens, Roshan S Prabhu, Michael B Livingston, Nicole L Gower, McKenzie Needham, Sally J Trufan, Ryan C Fields, Bradley A Krasnick, Meena Bedi, Konstantinos Votanopoulos, Konstantinos Chouliaras, Valerie Grignol, Kevin K Roggin, Jennifer Tseng, George Poultsides, Thuy B Tran, Kenneth Cardona, J Harrison Howard
BACKGROUND: Prognostic nomograms for patients with resected extremity soft tissue sarcoma (STS) include the Sarculator and Memorial Sloan Kettering (MSKCC) nomograms. We sought to validate these two nomograms within a large, modern, multi-institutional cohort of resected primary extremity STS patients. METHODS: Resected primary extremity STS patients from 2000 to 2017 were identified across nine high-volume U.S. institutions. Predicted 5- and 10-year overall survival (OS) and distant metastases cumulative incidence (DMCI), and 4-, 8-, and 12-year disease-specific survival (DSS) were calculated with Sarculator and MSKCC nomograms, respectively...
May 2022: Annals of Surgical Oncology