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https://www.readbyqxmd.com/read/27913077/pyloric-obstruction-secondary-to-epicardial-pacemaker-implantation-a-case-report
#1
G Bedoya Nader, H B Kellihan, D E Bjorling, J McAnulty
A 10-year old Lhasa Apso dog was presented for an acute history of exercise intolerance and hind limb weakness. High grade second degree atrioventricular block with an atrial rate of 200 beats per minute, ventricular rate of 40 beats per minute and an intermittent ventricular escape rhythm, was diagnosed on electrocardiograph. A transdiaphragmatic, unipolar, epicardial pacemaker was implanted without immediate surgical complications. Severe vomiting was noted 12 h post-operatively. Abdominal ultrasound and a barium study supported a diagnosis of pyloric outflow obstruction and exploratory abdominal surgery was performed...
November 29, 2016: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/27910058/gene-delivery-for-the-generation-of-bioartificial-pacemaker
#2
Patrick K W Chan, Ronald A Li
Electronic pacemakers have been used in patients with heart rhythm disorders for device-supported pacing. While effective, there are such shortcomings as limited battery life, permanent implantation of catheters, the lack of autonomic neurohumoral responses, and risks of lead dislodging. Here we describe protocols for establishing porcine models of sick sinus syndrome and complete heart block, and the generation of bioartificial pacemaker by delivering a strategically engineered form of hyperpolarization-activated cyclic nucleotide-gated pacemaker channel protein via somatic gene transfer to convert atrial or ventricular muscle cardiomyocytes into nodal-like cells that rhythmically fire action potentials...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27909539/right-ventricular-pacing-for-assessment-of-cavo-tricuspid-isthmus-block
#3
Ganesh Venkataraman Md, Marc Wish Md, Ted Friehling Md, S Adam Strickberger Md
Background: Cavo-tricuspid isthmus (CTI) dependent atrial flutter is typically treated with cardiac ablation. Standard techniques to assess CTI block after ablation can be technically challenging. Right ventricular (RV) pacing may allow for another technique to assess CTI block after ablation. Objective: The purpose of this study was to evaluate RV pacing as a method to assess CTI block after ablation of CTI dependent atrial flutter, and define endpoints of ablation using this technique. Methods: 28 patients undergoing ablation of CTI dependent atrial flutter with intact ventriculoatrial (VA) conduction were prospectively enrolled in this study and underwent the RV pacing protocol, as well as standard coronary sinus (CS) pacing techniques to assess CTI block...
August 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27909515/myocardial-biopsy-in-idiopathic%C3%A2-atrial-fibrillation-and-other-arrhythmias-nosological-diagnosis-clinical-and-morphological-parallels-and-treatment
#4
O V Blagova, A V Nedostup, E A Kogan, V A Sulimov, S A Abugov, A G Kupriyanova, V A Zaydenov, A E Donnikov, E V Zaklyazminskaya, E A Okisheva
BACKGROUND: The nosological nature of "idiopathic" arrhythmias and the effect of etiotropic and pathogenetic treatment are often unknown. METHODS AND RESULTS: 19 patients (42.6±11.3 years, 9 women) with atrial fibrillation (n = 16), supraventricular (n = 10) and ventricular (n = 4) premature beats, supraventricular (n = 2) and ventricular tachycardia (n = 1), left bundle branch block (n= 2), AV block (n = 2) without structural heart changes. Viruses were identified (polymerase chain reaction, PCR) along with measurement of anti-heart antibodies (AHA) and endomyocardial biopsy (EMB)...
June 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27909497/persistent-atrial-fibrillation-and-atrial-flutter-complicated-by-tachycardiomyopathy-because-of-intermittent-conduction-through-accessory-pathway
#5
L Valeri, A Coppolino, G Rossetti, A Vado, G Amoroso, G Bricco, A Battisti, L Correndo, S Dogliani, A Magliarditi, D Pancaldo, M De Benedictis, A Bassignana, B Doronzo
The term tachycardiomyopathy refers to a specific form of tachycardia-related cardiomyopathy caused by supraventricular or ventricular tachyarrhytmias that are both associated with ventricular rates higher than 120 bpm. The arrhythmias which are most frequently associated with these forms of heart disease are atrial fibrillation and atrial flutter, particularly found in the elderly population. The most frequent clinical manifestation is heart failure. In this case we are reporting a clinical case of a patient that came to our attention because of an episode of heart failure associated with atrial fibrillation and atrial flutter...
April 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27909485/supraventricular-tachycardia-with-irregular-ventricular-atrial-intervals-and-ventriculo-atrial-block
#6
Prof Dr Murat Sucu, Prof Dr Vedat Davutoglu, Dr Esra Polat
The patient was a 68-year-old female with recurrent paroxysmal, regular narrow QRS complex tachycardia. We observed complete VA conduction block, during tachycardia in our patient. A characteristic feature of our patient is the noticeable irregular atrial and ventricular rates. We considered that possible mechanism of this tachycardia was atrioventricular nodal reentrant tachycardia (AVNRT) with retrograde complete type block in the upper common pathway.
February 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27884249/long-term-arrhythmic-and-nonarrhythmic-outcomes-of-lamin-a-c-mutation-carriers
#7
Saurabh Kumar, Samuel H Baldinger, Estelle Gandjbakhch, Philippe Maury, Jean-Marc Sellal, Alexander F A Androulakis, Xavier Waintraub, Philippe Charron, Anne Rollin, Pascale Richard, William G Stevenson, Ciorsti J Macintyre, Carolyn Y Ho, Tina Thompson, Jitendra K Vohra, Jonathan M Kalman, Katja Zeppenfeld, Frederic Sacher, Usha B Tedrow, Neal K Lakdawala
BACKGROUND: Mutations in LMNA are variably expressed and may cause cardiomyopathy, atrioventricular block (AVB), or atrial arrhythmias (AAs) and ventricular arrhythmias (VA). Detailed natural history studies of LMNA-associated arrhythmic and nonarrhythmic outcomes are limited, and the prognostic significance of the index cardiac phenotype remains uncertain. OBJECTIVES: This study sought to describe the arrhythmic and nonarrhythmic outcomes of LMNA mutation carriers and to assess the prognostic significance of the index cardiac phenotype...
November 29, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27855290/transcatheter-leadless-cardiac-pacing-the-new-alternative-solution
#8
Antoine Da Costa, Amandine Axiotis, Cécile Romeyer-Bouchard, Loucif Abdellaoui, Zahi Afif, Jean Baptiste Guichard, Antoine Gerbay, Karl Isaaz
INTRODUCTION: A lack of information about the feasibility and safety of leadless pacemaker (LPMs) exists in a fragile population of patients with limited venous anatomy access or conventional pacemaker (PM) contraindication. Accordingly, the goal of this prospective observational study was to report our experience with this new leadless technology in a subset of patients with contraindication or limited venous access. METHODS AND RESULTS: Between May 2015 and July 2016, 14 patients were consecutively included...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27847261/clinically-apparent-long-term-electric-disturbances-in-the-acute-and-very-long-term-of-patent-foramen-ovale-device-based-closure
#9
Gianluca Rigatelli, Marco Zuin, Luigi Pedon, Roberto Zecchel, Fabio Dell'Avvocata, Antonio Carrozza, Marco Zennaro, Gianni Pastore, Francesco Zanon
BACKGROUND/PURPOSE: Incidence of electrical disturbances in patients submitted to transcatheter patent foramen ovale (PFO) closure has not been fully clarified in a large population. The aim of the study is to assess the incidence of atrial fibrillation, supraventricular tachi-arrhythmias, and atrio-ventricular block in the acute and very long-term follow-up. METHODS/MATERIALS: We reviewed the medical and instrumental data of 1000 consecutive patients (mean age 47...
October 29, 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/27844192/-right-bundle-branch-block-during-right-ventricular-pacing
#10
Harilaos Bogossian, Fuad Hasan, Gerrit Frommeyer, Bernd Lemke, Markus Zarse
INTRODUCTION: We describe the case of a 78-year-old patient who presented for ablation of a wide complex tachycardia with right bundle branch block (RBBB) morphology. A pacemaker spike at the QRS onset indicated supraventricular tachycardia with AV synchronous ventricular pacemaker activation. METHODS: Correct positioning of the ventricular lead in the right ventricular apex was confirmed by fluoroscopy and echocardiography, excluding malpositioning of the right ventricular lead...
November 14, 2016: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/27836293/asymptomatic-atrial-fibrillation-in-patients-with-atrial-fibrillation-and-implanted-pacemaker
#11
Michal Witkowski, Andrzej Bissinger, Tomasz Grycewicz, Andrzej Lubinski
INTRODUCTION: Atrial fibrillation is the most common chronic arrhythmia. Due to diagnostic difficulties, the exact prevalence of silent atrial fibrillation is not precisely defined. AIM: The main aim of the present study was to assess the prevalence of asymptomatic atrial fibrillation and the relation between clinical status and presence of symptoms of atrial fibrillation. MATERIAL AND METHODS: Fifty patients with implanted pacemaker with atrial fibrillation recording function and diagnosed paroxysmal atrial fibrillation were enrolled to the study in order to detect episodes of atrial fibrillation...
November 5, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27833552/hydrogen-h2-inhibits-isoproterenol-induced-cardiac-hypertrophy-via-antioxidative-pathways
#12
Yaxing Zhang, Jingting Xu, Zhiyuan Long, Chen Wang, Ling Wang, Peng Sun, Ping Li, Tinghuai Wang
Background and Purpose: Hydrogen (H2) has been shown to have a strong antioxidant effect on preventing oxidative stress-related diseases. The goal of the present study is to determine the pharmacodynamics of H2 in a model of isoproterenol (ISO)-induced cardiac hypertrophy. Methods: Mice (C57BL/6J; 8-10 weeks of age) were randomly assigned to four groups: Control group (n = 10), ISO group (n = 12), ISO plus H2 group (n = 12), and H2 group (n = 12). Mice received H2 (1 ml/100g/day, intraperitoneal injection) for 7 days before ISO (0...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27830772/diagnosis-pathophysiology-and-management-of-exercise-induced-arrhythmias
#13
REVIEW
Eduard Guasch, Lluís Mont
The cardiovascular benefits of physical activity are indisputable. Nevertheless, growing evidence suggests that both atrial fibrillation and right ventricular arrhythmia can be caused by intense exercise in some individuals. Exercise-induced atrial fibrillation is most commonly diagnosed in middle-aged, otherwise healthy men who have been engaged in endurance training for >10 years, and is mediated by atrial dilatation, parasympathetic enhancement, and possibly atrial fibrosis. Cardiac ablation is evolving as a first-line tool for athletes with exercise-induced arrhythmia who are eager to remain active...
November 10, 2016: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/27812768/impact-of-anteroinferior-transseptal-puncture-on-creation-of-a-complete-block-at-the-mitral-isthmus-in-patients-with-atrial-fibrillation
#14
Kenji Okubo, Taishi Kuwahara, Masateru Takigawa, Yasuaki Tanaka, Jun Nakajima, Yuji Watari, Emiko Nakashima, Kazuya Yamao, Yuichiro Sagawa, Katsumasa Takagi, Tadashi Fujino, Hiroyuki Tsutsui, Atsushi Takahashi
PURPOSE: Achieving complete mitral isthmus (MI) conduction block for atrial fibrillation (AF) ablation remains challenging. We hypothesized that transseptal puncture (TSP) at the anteroinferior aspect of the atrial septum (anteroinferior TSP) could shorten the distance to the MI and improve catheter contact and stability, enabling complete MI block. This study investigated the efficacy of anteroinferior TSP for MI ablation in AF patients. METHODS: Three hundred and twenty consecutive patients (mean age: 62 ± 9 years, 84 % male) with persistent AF undergoing AF ablation, including MI ablation, were enrolled...
November 3, 2016: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/27809950/effects-of-prenatal-bisphenol-a-exposure-and-postnatal-overfeeding-on-cardiovascular-function-in-female-sheep
#15
S M J MohanKumar, T D Rajendran, A K Vyas, V Hoang, N Asirvatham-Jeyaraj, A Veiga-Lopez, N B Olivier, V Padmanabhan, P S MohanKumar
Bisphenol-A (BPA) is a widely used endocrine-disrupting chemical. Prenatal exposure to BPA is known to affect birth weight, but its impact on the cardiovascular system has not been studied in detail. In this study, we investigated the effects of prenatal BPA treatment and its interaction with postnatal overfeeding on the cardiovascular system. Pregnant sheep were given daily subcutaneous injections of corn oil (control) or BPA (0.5 mg/kg/day in corn oil) from day 30 to day 90 of gestation. A subset of female offspring of these dams were overfed to increase body weight to ~30% over that of normal fed controls...
November 4, 2016: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/27775552/transcription-factor-etv1-is-essential-for-rapid-conduction-in-the-heart
#16
Akshay Shekhar, Xianming Lin, Fang-Yu Liu, Jie Zhang, Huan Mo, Lisa Bastarache, Joshua C Denny, Nancy J Cox, Mario Delmar, Dan M Roden, Glenn I Fishman, David S Park
Rapid impulse propagation in the heart is a defining property of pectinated atrial myocardium (PAM) and the ventricular conduction system (VCS) and is essential for maintaining normal cardiac rhythm and optimal cardiac output. Conduction defects in these tissues produce a disproportionate burden of arrhythmic disease and are major predictors of mortality in heart failure patients. Despite the clinical importance, little is known about the gene regulatory network that dictates the fast conduction phenotype. Here, we have used signal transduction and transcriptional profiling screens to identify a genetic pathway that converges on the NRG1-responsive transcription factor ETV1 as a critical regulator of fast conduction physiology for PAM and VCS cardiomyocytes...
December 1, 2016: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27748530/sudden-death-and-its-risk-factors-after-atrioventricular-junction-ablation-and-pacemaker-implantation-in-patients-with-atrial-fibrillation
#17
Ru-Xing Wang, Hon-Chi Lee, Jia-Ping Li, David O Hodge, Yong-Mei Cha, Paul A Friedman, Thomas M Munger, Komandoor Srivathsan, Behzad B Pavri, Win-Kuang Shen
BACKGROUND: Although sudden death (SD) is a rare complication after atrioventricular junction (AVJ) ablation and permanent pacemaker implantation, the risk factors leading to this SD remain unknown. The purpose of this study was to investigate SD and its risk factors after ablate-and-pace strategy for rate control in atrial fibrillation (AF) patients during long-term follow-up. HYPOTHESIS: METHODS: From January 2005 to December 2009, we enrolled into this study 517 AF patients with AVJ ablation and right ventricular pacemaker implantation...
October 17, 2016: Clinical Cardiology
https://www.readbyqxmd.com/read/27743468/a-monolithic-3d-0d-coupled-closed-loop-model-of-the-heart-and-the-vascular-system-experiment-based-parameter-estimation-for-patient-specific-cardiac-mechanics
#18
M Hirschvogel, M Bassilious, L Jagschies, S M Wildhirt, M W Gee
A model for patient-specific cardiac mechanics simulation is introduced, incorporating a 3-dimensional finite element model of the ventricular part of the heart which is coupled to a reduced-order 0-dimensional closed-loop vascular system, heart valve and atrial chamber model.The ventricles are modeled by a nonlinear orthotropic passive material law. The electrical activation is mimicked by a prescribed parametrized active stress acting along a generic muscle fiber orientation. Our activation function is constructed such that the start of ventricular contraction and relaxation as well as the active stress curve's slope are parameterized...
October 15, 2016: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/27742755/percutaneous-balloon-atrial-septostomy-on-top-of-venoarterial-extracorporeal-membrane-oxygenation-results-in-safe-and-effective-left-heart-decompression
#19
Alban-Elouen Baruteau, Thomas Barnetche, Luc Morin, Zakaria Jalal, Nicholas S Boscamp, Emmanuel Le Bret, Jean-Benoit Thambo, Julie A Vincent, Alain Fraisse, Alejandro J Torres
BACKGROUND: Transcatheter techniques are emerging for left atrial (LA) decompression under venoarterial extracorporeal membrane oxygenation (VA-ECMO). We aimed to assess whether balloon atrioseptostomy (BAS) is a safe and efficient strategy. METHODS: All patients who underwent percutaneous static BAS under VA-ECMO at four tertiary institutions were retrospectively reviewed. RESULTS: From 2000 to 2014, BAS was performed in 64 patients (32 adults and 32 children)...
October 14, 2016: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/27738753/-predictors-for-need-of-antibradycardia-and-antitachycardia-pacing-after-icd-implantation-implications-for-the-subcutaneous-icd
#20
Martin Grett, Martin Christ, Hans-Joachim Trappe
BACKGROUND: Little is known about the incidence and risk factors for progression to pacemaker dependency or the need for cardiac resynchronization in typical patients with an implanted defibrillator with regard to an alternative implantation of a subcutaneous ICD (S-ICD). STUDY DESIGN AND METHODS: After retrospective analysis of 291 patients with first implantation of a transvenous single chamber ICD (VVI-ICD) from 2010-2016 and excluding those with an indication for pacemaker or lack of follow-up data, 121 patients were included and investigated with regard to the following endpoints: need for pacemaker stimulation, upgrade for cardiac resynchronization (CRT), and secondary occurrence and effectiveness of antitachycardia pacing (ATP)...
October 13, 2016: Herzschrittmachertherapie & Elektrophysiologie
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