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https://www.readbyqxmd.com/read/29903630/automated-diagnosis-of-arrhythmia-using-combination-of-cnn-and-lstm-techniques-with-variable-length-heart-beats
#1
Shu Lih Oh, Eddie Y K Ng, Ru San Tan, U Rajendra Acharya
Arrhythmia is a cardiac conduction disorder characterized by irregular heartbeats. Abnormalities in the conduction system can manifest in the electrocardiographic (ECG) signal. However, it can be challenging and time-consuming to visually assess the ECG signals due to the very low amplitudes. Implementing an automated system in the clinical setting can potentially help expedite diagnosis of arrhythmia, and improve the accuracies. In this paper, we propose an automated system using a combination of convolutional neural network (CNN) and long short-term memory (LSTM) for diagnosis of normal sinus rhythm, left bundle branch block (LBBB), right bundle branch block (RBBB), atrial premature beats (APB) and premature ventricular contraction (PVC) on ECG signals...
June 5, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29897909/electrocardiographic-abnormalities-in-chagas-disease-in-the-general-population-a-systematic-review-and-meta-analysis
#2
Lyda Z Rojas, Marija Glisic, Laura Pletsch-Borba, Luis E Echeverría, Wichor M Bramer, Arjola Bano, Najada Stringa, Asija Zaciragic, Bledar Kraja, Eralda Asllanaj, Rajiv Chowdhury, Carlos A Morillo, Oscar L Rueda-Ochoa, Oscar H Franco, Taulant Muka
BACKGROUND: Chagas disease (CD) is a major public health concern in Latin America and a potentially serious emerging threat in non-endemic countries. Although the association between CD and cardiac abnormalities is widely reported, study design diversity, sample size and quality challenge the information, calling for its update and synthesis, which would be very useful and relevant for physicians in non-endemic countries where health care implications of CD are real and neglected. We performed to systematically review and meta-analyze population-based studies that compared prevalence of overall and specific ECG abnormalities between CD and non-CD participants in the general population...
June 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29863096/prognostic-value-of-electrocardiography-in-patients-with-fulminant-myocarditis-supported-by-percutaneous-venoarterial-extracorporeal-membrane-oxygenation-analysis-from-the-change-pump-study
#3
Akinori Sawamura, Takahiro Okumura, Masaaki Ito, Yukio Ozaki, Nobuyuki Ohte, Tetsuya Amano, Toyoaki Murohara
BACKGROUND: Fulminant myocarditis (FM) presents various abnormal findings on ECG, the prognostic impact of which has not been not fully elucidated. The aim of this study was therefore to clarify the prognostic value of ECG data in FM patients supported by venoarterial extracorporeal membrane oxygenation (VA-ECMO).Methods and Results:In this multicenter chart review, we investigated 99 patients with FM supported by VA-ECMO. The final cohort consisted of 87 patients (mean age, 52±16 years; female, 42%) after 12 patients who required conversion to other forms of mechanical circulatory support were excluded...
June 1, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29800750/acute-biventricular-hemodynamic-effects-of-cardiac-resynchronization-therapy-in-right-bundle-branch-block
#4
Brian A Houston, J Lacy Sturdivant, Yinghong Yu, Michael R Gold
BACKGROUND: Controversy remains regarding the utility of cardiac resynchronization therapy (CRT) in heart failure patients with right bundle branch block (RBBB) and reduced left ventricular ejection fraction. Moreover, little is known regarding the acute hemodynamic changes with CRT in this subgroup compared with LBBB. OBJECTIVE: To understand the effects of cardiac resynchronization therapy (CRT) in RBBB patients, this study evaluated the acute biventricular hemodynamic response of CRT and other pacing configurations, including the effects of AV delay and atrial pacing METHODS: Forty patients (9 with RBBB and 31 with LBBB) undergoing CRT implantation underwent temporary pacing with varying configurations and AV delay...
May 22, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29797853/-ecg-interpretation-and-clinical-significance-of-p-wave-abnormalities
#5
Nicolas Johner, Mehdi Namdar, Dipen Shah
The ECG provides information about heart rhythm and myocardial integrity, including the atria. The sinus P wave exhibits a 0‑90° axis and a generally biphasic morphology in lead V1. An amplitude >2 mm in lead II and >1 mm in lead V1 is a specific sign of right atrial enlargement, often related to pulmonary disease or pulmonary hypertension. Interatrial block (IAB) is defined as a P-wave ≥120 ms with, in the advanced form, a biphasic morphology in inferior leads. It is most commonly seen in the context of advanced age, cardiovascular risk factors, coronary artery disease or valvulopathies...
May 23, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29786701/lutembacher-syndrome-with-mitral-valve-calcification-in-a-31-year-old-male
#6
Arsalan Majeed Adam, Ansab Godil, Muhammad Saad Ali Mallick, Fahad Khan, Ather Hasan Rizvi, Inam-Ul-Haq Muhammad Makhdoom
Lutembacher syndrome is characterized by a congenital ostium secundum atrial septal defect and an acquired mitral valve stenosis. We present a similar case in a 31-year old male who came in with orthopnoea, central cyanosis and pedal oedema. Examination revealed cardiac murmurs in tricuspid and apical regions. Chest x-ray showed signs of pulmonary congestion and ventricular enlargement. Electrocardiogaphy (ECG) revealed right axis deviation and right bundle branch block along with atrial fibrillation and Transthoracic Echocardiography (TTE) showed abnormal valves (mitral stenosis with calcification and tricuspid regurgitation) and dilated cardiac chambers...
February 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/29782250/-effect-of-right-ventricular-myocardial-contractility-on-the-response-to-cardiac-resynchronization-therapy
#7
D I Lebedev, S V Popov, A I Mishkina, M V Lebedeva
AIM: To determine the effect of right ventricular myocardial contractility on the response to cardiac resynchronization therapy (CRT). MATERIALS AND METHODS: The study included 80 patients (49 men, mean age 54±10.5) diagnosed with dilated cardiomyopathy, complete left bundle branch block, and the QRS complex width 146 to 240 ms (183±32 ms). Heart failure was NYHA FC III, ejection fraction (EF) - 30.1±3.8 %, 6‑min walk test - 290.5±64.3 m, and end-diastolic volume (EDV) - 220...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29781518/an-interesting-case-of-wide-qrs-tachycardia-with-right-bundle-branch-block-morphology-what-is-the-mechanism
#8
Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Hiren Kevadiya, Ajitkumar Valaparambil
A 30 year old gentleman with no structural heart disease has been evaluated for paroxysmal palpitation with documented regular wide QRS tachycardia that has not responded to IV adenosine. Surface electrocardiogram has not shown any pre-excitation. He has been taken for an EP study after informed consent. Diagnostic catheters were placed at coronary sinus (CS), His bundle region and right ventricle (RV). During catheter manipulation a regular wide QRS tachycardia with right bundle branch block morphology (RBBB) with a tachycardia cycle length (TCL) of 400 ms and normal QRS axis similar to the clinical tachycardia got induced (Fig:1)...
May 21, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29779522/sinus-tachycardia-presenting-as-a-wide-and-narrow-complex-tachyarrhythmia-what-is-the-link
#9
Chenni S Sriram, Mario D Gonzalez
We describe a neonate that developed alternating wide and narrow complex tachycardias following heart surgery for congenital heart defect. Although the etiology was sinus tachycardia, a premature atrial complex initiated aberrancy due to phase 3 block that was perpetuated due to 'linking' at similar or even slower heart rates. Similarly, there was abrupt transition from wide to narrow complex tachycardia following a premature ventricular complex without a change in subsequent heart rate. This was explained by interruption of linking phenomenon by premature ventricular activation...
May 2018: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29778339/lower-risk-of-postoperative-arrhythmias-in-congenital-heart-surgery-following-intraoperative-administration-of-magnesium
#10
Dingchao He, Nimisha Aggarwal, David Zurakowski, Richard A Jonas, Charles I Berul, Sridhar Hanumanthaiah, Jeffrey P Moak
OBJECTIVES: Postoperative arrhythmias are common in children undergoing congenital heart surgery. We evaluated whether intraoperative administration of magnesium was associated with a reduced occurrence of specific postoperative arrhythmias, as has been described previously, or had a broader effect on multiple arrhythmia types, and whether there existed a dose-effect of intraoperative magnesium. METHODS: We used a historical prospective observational cohort study...
April 18, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29758405/accelerometer-based-av-synchronous-pacing-with-a-ventricular-leadless-pacemaker-results-from-the-micra-av-feasibility-studies
#11
Larry Chinitz, Philippe Ritter, Surinder Kaur Khelae, Saverio Iacopino, Christophe Garweg, Maria Grazia-Bongiorni, Petr Neuzil, Jens Brock Johansen, Lluis Mont, Efrain Gonzalez, Venkata Sagi, Gabor Z Duray, Nicolas Clementy, Todd Sheldon, Vincent Splett, Kurt Stromberg, Nicole Wood, Clemens Steinwender
BACKGROUND: Micra is a leadless pacemaker that is implanted in the right ventricle and provides rate response via a 3-axis accelerometer (ACC). Custom software was developed to detect atrial contraction using the ACC enabling AV synchronous pacing. OBJECTIVE: To sense atrial contractions from the Micra ACC signal and provide AV synchronous pacing. METHODS: The MASS/MASS2 early feasibility studies showed intracardiac accelerations related to atrial contraction can be measured via ACC in the Micra leadless pacemaker...
May 8, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29739637/adverse-effects-of-left-ventricular-electrical-dyssynchrony-on-cardiac-reverse-remodeling-and-prognosis-after-aortic-valve-surgery
#12
Soo Youn Lee, Chi Young Shim, Geu-Ru Hong, In Jeong Cho, Seng Chan You, Hyuk-Jae Chang, Jong-Won Ha, Namsik Chung
BACKGROUND: Electrical dyssynchrony (ED) is one of the important contributing mechanisms in the progression of heart failure. We hypothesized that ED would interfere with cardiac reverse remodeling and affect prognosis after aortic valve surgery. METHODS: A total of 411 consecutive patients (233 males, mean age 65±11 years) who underwent aortic valve surgery were retrospectively analyzed. The patients were divided into two groups according to the presence of ED [Group 1: no ED (n=382, 93%), Group 2: ED (n=29, 7%)]...
May 5, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29686877/how-to-manage-various-arrhythmias-and-sudden-cardiac-death-in-the-cardiovascular-intensive-care
#13
REVIEW
Yoshinori Kobayashi
In the clinical practice of cardiovascular critical care, we often observe a variety of arrhythmias in the patients either with (secondary) or without (idiopathic) underlying heart diseases. In this manuscript, the clinical background and management of various arrhythmias treated in the CCU/ICU will be reviewed. The mechanism and background of lethal ventricular tachyarrhythmias vary as time elapses after the onset of MI that should be carefully considered to select a most suitable therapy. In the category of non-ischemic cardiomyopathy, several diseases are known to be complicated by the various ventricular tachyarrhythmias with some specific mechanisms...
2018: Journal of Intensive Care
https://www.readbyqxmd.com/read/29673006/electro-vectorcardiographic-demonstration-of-bifascicular-block-associated-with-ventricular-preexcitation
#14
Andrés R Pérez-Riera, Raimundo Barbosa-Barros, Rodrigo Daminello-Raimundo, Luiz Carlos de Abreu, Kjell Nikus
Down syndrome occurs more frequently in the offsprings of older pregnant women and may be associated with atrioventricular septal defect. This refers to a broad spectrum of malformations characterized by a deficiency of the atrioventricular septum and abnormalities of the atrioventricular valves caused by an abnormal fusion of the superior and inferior endocardial cushions with the midportion of the atrial septum and the muscular portion of the ventricular septum.
April 19, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29652656/electrocardiogram-abnormalities-related-to-anti-malarials-in-systemic-lupus-erythematosus
#15
Taneisha K McGhie, Paula Harvey, Jiandong Su, Nicole Anderson, George Tomlinson, Zahi Touma
OBJECTIVES: Cardiotoxicity with potential conduction/structural abnormalities on electrocardiogram (ECG) have been reported with anti-malarial (AM). We aimed to study whether cumulative AM is associated with ECG abnormalities. METHODS: A standard resting supine ECG was performed on consecutive patients attending the Lupus Clinic since 2012. ECG abnormalities were grouped into structural [left ventricular hypertrophy or atrial enlargement] and conduction abnormalities [prolonged corrected QT interval (QTc), short PR interval, left bundle branch block (LBBB), right bundle branch block (RBBB) and atrioventricular block (AVB), bradycardia, tachycardia, premature atrial complex, ectopic atrial rhythm, atrial fibrillation, premature ventricular complex and ventricular bigeminy]...
April 13, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29644942/postnatal-undernutrition-in-mice-causes-cardiac-arrhythmogenesis-which-is-exacerbated-when-pharmacologically-stressed
#16
J R Visker, D P Ferguson
Growth restriction caused by postnatal undernutrition increases risk for cardiovascular disease in adulthood with the potential to induce arrhythmogenesis. Thus, the purpose was to determine if undernutrition during development produced arrhythmias at rest and when stressed with dobutamine in adulthood. Mouse dams were fed (CON: 20% protein), or low-protein (LP: 8%) diet before mating. A cross-fostering model was used where pups nursed by dams fed LP diet in early [EUN; postnatal day (PN) 1-10], late (LUN; PN11-21) and whole (PUN; 1-21) phases of postnatal life...
April 12, 2018: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/29628444/ph-domain-leucine-rich-repeat-protein-phosphatase-2-phlpp2-regulates-g-protein-coupled-receptor-kinase-5-grk5-induced-cardiac-hypertrophy-in-vitro
#17
Szu-Tsen Yeh, Cristina M Zambrano, Walter J Koch, Nicole H Purcell
PH domain leucine-rich repeat protein phosphatase (PHLPP) is a serine/threonine phosphatase that has been shown to regulate cell growth and survival through dephosphorylation of several members of the AGC family of kinases. G-protein-coupled receptor kinase 5 (GRK5) is an AGC kinase that regulates phenylephrine (PE)-induced cardiac hypertrophy through its noncanonical function of directly targeting proteins to the nucleus to regulate transcription. Here we investigated the possibility that the PHLPP2 isoform can regulate GRK5-induced cardiomyocyte hypertrophy in neonatal rat ventricular myocytes (NRVMs)...
May 25, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29625102/tricuspid-valve-detachment-in-ventricular-septal-defect-closure-does-not-impact-valve-function
#18
Charles D Fraser, Xun Zhou, Sandeep Palepu, Cecillia Lui, Alejandro Suarez-Pierre, Todd C Crawford, J Trent Magruder, Marshall L Jacobs, Duke E Cameron, Narutoshi Hibino, Luca A Vricella
BACKGROUND: Although tricuspid valve detachment (TVD) facilitates improved exposure during transatrial ventricular septal defect (VSD) closure, few have analyzed the impact of TVD on long-term valve durability. METHODS: Pediatric patients undergoing VSD closure at our institution from 1997 to 2013 were identified, and charts were retrospectively reviewed. Patients were separated into groups based on utilization of TVD. Propensity score matching was then performed using a nonparsimonious logistic regression model involving 7 variables...
April 3, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29610591/does-phantom-tumor-really-exist
#19
Dan-Nicolae Tesloianu, Mihaela Chioarta, Dana Corduneanu, Andreea-Mihaela Ignat, Antoniu Octavian Petris, Anda Tesloianu
Localized interlobar effusion in congestive heart failure (known as phantom tumor or vanishing tumor of the lung) is an uncommon entity. We report a case of a 61-year-old man who presented to the Emergency Departament with a two week history of dyspnoea, palpitations, dry cough and intermitent anterior chest pain. A posteroanterior chest radiography showed a nodular mass in the medium third of the right hemithorax suggestive of a pulmonary tumor. With this supposition of diagnosis, the patient was admitted to the Pneumology Departament for further investigations...
December 2017: Mædica
https://www.readbyqxmd.com/read/29570208/sheep-can-be-used-as-animal-model-of-regional-myocardial-remodelling-and-controllable-work
#20
Jürgen Duchenne, Piet Claus, Efstathios D Pagourelias, Razvan O Mada, Joeri Van Puyvelde, Kathleen Vunckx, Eric Verbeken, Olivier Gheysens, Filip Rega, Jens-Uwe Voigt
BACKGROUND: A-V-sequential pacing has been shown to induce reversible conduction delay and subsequent asymmetric remodelling of the left ventricle (LV) in dogs and pigs. Both species have disadvantages in animal experiments. Therefore aim of this study focusses at developing a more feasible and easy-to-use animal model in sheep. METHODS: Dual-chamber pacing (DDD) pacemakers (right atrium + right ventricular free wall) were surgically implanted in 13 sheep. All animals underwent 8 weeks of chronic rapid pacing at 180 bpm...
March 23, 2018: Cardiology Journal
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