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Aquacel silver dressing

Aamna Shah, Izhar Hussain, Ghulam Murtaza
This study provides the optimum preparation parameters for functional chitosan silver nanocomposite (CSN) films with promising antibacterial efficacy though prepared with very low silver nitrate (AgNO3 ) concentration. Chitosan nano‑silver composites were fabricated by In-situ chemical method utilizing the reducing ability of sodium borohydride (NaBH4 ) and afterward casted into films. Utilization of response surface methodology, NCSS, and SigmaPlot for the optimization of CSN and their predicted antibacterial efficacy assessment of the selected bacterial strains (standard and clinical) was the essential part of the study...
May 11, 2018: International Journal of Biological Macromolecules
Piotr Szweda, Grzegorz Gorczyca, Robert Tylingo
OBJECTIVE: The aim of our study was to examine the antimicrobial potential of eight selected, commercially available wound dressings containing different antimicrobial agents: silver, chlorhexidine acetate, povidone-iodine, and manuka honey. METHOD: The materials were tested against four reference strains of bacteria: Staphylococcus aureus (PCM 2051), Staphylococcus epidermidis (PCM 2118), Pseudomonas aeruginosa (ATCC 27853), and Escherichia coli (K12), using the disc diffusion-like method and a time-killing assay...
May 2, 2018: Journal of Wound Care
Young Suk Choi, Heui-Chul Gwak, Jae Keun Park, Ji Yun Lim, Eui Dong Yeo, Eunseok Park, Junyong Kim, Young Koo Lee
INTRODUCTION: Silver nanoparticle (AgNP)-containing dressings are used worldwide for the treatment of wounds; however, many studies have indicated that AgNPs are toxic to humans and cause cell death, primarily via apoptosis. OBJECTIVE: In this study, the investigators compare the apoptotic effects of various AgNP dressing materials, with the hypothesis that nanosilver would be less toxic than ionic silver. MATERIALS AND METHODS: For the in vivo experiments, Sprague-Dawley (SD) and streptozotocin (STZ)-induced diabetic rats were treated with 5 dressing materials: Aquacel Ag (product A, silver ion; ConvaTec, Berkshire, UK), Acticoat (product B, AgNP; Smith & Nephew, Fort Worth, TX), Medifoam Silver (product C, silver ion; Genewel Science Co Ltd, Seongnam, South Korea), PolyMem Silver (product D, AgNP; Ferris Mfg Corp, Fort Worth, TX), and Vaseline-impregnated dressing gauze (control; Unilever, London, UK)...
April 13, 2018: Wounds: a Compendium of Clinical Research and Practice
Gergo Jozsa, Peter Vajda, Andras Garami, Alexandra Csenkey, Zsolt Juhasz
RATIONALE: Burns is a common type of traumatic injury in childhood. Nowadays, several wound dressings are available to treat the second-degree hand burns conservatively. PATIENT CONCERNS, DIAGNOSES: At the authors' institute, 37 children were treated conservatively with a special dressing at first intervention containing Aquacel Ag foam and Zn-hyaluronic gel to determine their effectiveness on partial thickness hand burns. INTERVENTIONS: The dressing was checked on the second day, and removed on the sixth or seventh day (unless it had spontaneously separated)...
March 2018: Medicine (Baltimore)
G Józsa, E Tóth, Zs Juhász
Burns are among the most common causes of injury in children. Several wound dressings are available to conservatively treat second-degree burns. Seventy-three children were treated with Aquacel Ag foam and Zn-hyaluronon gel to determine their effectiveness on partial thickness burns. We applied silver nitrate solution on 25% of patients for 24 hrs, then checked burn depth. If the burn was superficial second degree, we applied the dressing under study. All dressings were removed 6-7 days later. In the remaining children we used Aquacel Ag foam dressing with Zn-hyaluronon gel at first intervention...
March 31, 2017: Annals of Burns and Fire Disasters
Katie A Bourdillon, Craig P Delury, Breda M Cullen
This study investigated whether there are differences in the ability of wound dressings to modulate certain factors known to affect wound healing. A selection of antimicrobial dressings (AQUACEL® Ag Extra™ , AQUACEL® Ag+ Extra™ , IODOFLEX™ , ACTICOAT™ 7 and PROMOGRAN PRISMA™ matrix) were tested for their effect on both bacterial bioburden and human dermal fibroblasts. Some dressings underwent further evaluation for activity against Pseudomonas aeruginosa biofilms using a colony-drip flow reactor model...
December 2017: International Wound Journal
E de Graaf, M E van Baar, M G A Baartmans, S M H J Scholten-Jaegers, M K Nieuwenhuis, J Eshuis, J Hiddingh, G I J M Beerthuizen, C H van der Vlies
AIM: The aim of this study was to compare the clinical outcomes of different treatment strategies for children with partial-thickness scalds at two burn centers. At the first burn center, these burns were treated with a hydrofiber dressing (Aquacel(®), Convatec, Inc.(®), Princeton, NJ, USA) or silver sulfadiazine (SSD, Flammazine(®), Sinclair IS Pharma, London, UK Pharmaceuticals), while at the second burn center, cerium nitrate-silver sulfadiazine (CN-SSD, Flammacerium(®), Sinclair IS Pharma, London, UK Pharmaceuticals) was used...
December 28, 2016: Burns: Journal of the International Society for Burn Injuries
Matthew J Grosso, Ari Berg, Samuel LaRussa, Taylor Murtaugh, David P Trofa, Jeffrey A Geller
BACKGROUND: Commercial silver-impregnated occlusive dressings (such as Aquacel Ag Surgical wound dressing) have been touted as antimicrobial dressings to be used following total joint arthroplasty. Given the increased cost of an Aquacel dressing over a standard dressing for total joint arthroplasty, the objective of this study was to determine whether Aquacel surgical dressing is effective in reducing the rates of acute periprosthetic joint infection (PJI) compared to standard sterile dressing...
March 2017: Journal of Arthroplasty
C T Lau, K K Y Wong, P Tam
INTRODUCTION: Burn injury is one of the most common reasons for admission in paediatric population. There is currently no international consensus on the best wound dressing material. Aquacel Ag, a new silver containing hydrofiber dressing material has been reported to produce good clinical results. Yet, only a limited number of studies exist in the paediatric population. This study aims to review our experience of burn management over the past 5 years and to evaluate the effectiveness of Aquacel Ag in the management of partial thickness burns...
June 2016: Pediatric Surgery International
Shunji Yunoki, Masushi Kohta, Yoshimi Ohyabu, Tetsuji Iwasaki
PURPOSE: This study evaluated the in vitro antibacterial activity and cytotoxicity of various commercially available silver-containing dressings (Ag dressing). METHODS: Biohesive Ag (hydrocolloid, silver sulfadiazine), Aquacel® Ag (nonwoven fabric, ionic silver [Ag]), Algisite™ Ag (nonwoven fabric, Ag), Mepilex® Ag (foam, silver sulfate), and PolyMem® Ag (foam, nanocrystalline silver) were tested for characteristics of Ag release, antibacterial activity, and cytotoxicity...
October 2015: Plastic Surgical Nursing
Zejun Pei, Qing Sun, Xin Sun, Yaping Wang, Peng Zhao
The infection in burn wounds covered by biologic dressings leads to wound deepening and chronic wounds. The introduction of silver nanoparticles (AgNPs) into biologic dressings is a beneficial method to prevent wound infection and simultaneously promote wound healing. In this study, an AgNP-loaded silk fibroin (SF)/carboxymethylchitosan (CMC) composite sponge was fabricated. AgNPs with a mean diameter of 4.9 nm was synthesized in SF solution in situ. While CMC was incorporated and chemically crosslinked, SF was insolubilized by ethanol annealing...
2015: Bio-medical Materials and Engineering
Nedeljka Glavan, Nives Jonjić
Three case reports on conservative treatment of posttraumatic open conquassant wounds in children are presented. In 2 cases, the wounds opened after rejection of a previously applied skin graft, whereas in the third case, the wound was consequential to toe amputation and treated conservatively. Based on the authors' long-standing favorable experience with this type of dressing in healing of deep burns in children, treatment was continued with the use of a hydrofiber supportive silver-containing dressing (AQUACEL Ag, ConvaTec, Bridgewater, NJ)...
September 2015: Wounds: a Compendium of Clinical Research and Practice
Matthew Brown, Stuart R Dalziel, Eleanor Herd, Kathryn Johnson, Richard Wong She, Michael Shepherd
Silver-impregnated dressings are increasingly preferred over silver sulfadiazine cream in the management of pediatric burns. An ideal burns dressing would provide a moist, sterile environment, discourage infection, and not require painful dressing changes. This study sought to determine whether silver sodium carboxymethyl cellulose (Aquacel Ag, ConvaTec, Greensboro, NC) dressing is a superior treatment to nanocrystalline silver-coated polyethylene (Acticoat, Smith & Nephew, London, United Kingdom) dressing in pediatric patients with partial thickness burns...
July 2016: Journal of Burn Care & Research: Official Publication of the American Burn Association
Yu-Hsin Lin, Wei-Shan Hsu, Wan-Yu Chung, Tse-Hao Ko, Jui-Hsiang Lin
Various types of wound dressings have been designed for different purposes and functions. Controlling bacterial burden in a wound during the early phase is important for successful wound repair. Once bacterial burden is under control, the active promotion of wound healing is another important factor for efficient wound healing. This study investigated the potential of three silver-containing dressings, namely KoCarbonAg(®) , Aquacel(®) Ag and Acticoat 7, in reducing bacterial survival and promoting wound healing...
August 2016: International Wound Journal
Manuel Gago, Fernando Garcia, Victoriana Gaztelu, Jose Verdu, Pablo Lopez, Andreu Nolasco
UNLABELLED: Objective. To compare 3 types of silver dressing in the typical clinical conditions of a community health center, regarding the time to achieve resolution of clinical signs of local infection, and wound healing progress over 8 weeks. METHODS: A prospective, comparative study involving 75 patients with infected chronic wounds who were divided into 3 treatment groups: Acticoat™ (group 1); Comfeel® Ag hydrocolloid/Biatain® Ag polyurethane foam (group 2); and Aquacel® Ag (group 3)...
October 2008: Wounds: a Compendium of Clinical Research and Practice
Yavuz Basterzi, Gulden Ersoz, Guliz Sarac, Alper Sari, Ferit Demirkan
UNLABELLED: Many new antimicrobial dressings have been used for the treatment of or protection against wound infection since the early 1980s. There are many different wound dressings such as silver, povidone iodine, and chlorhexidine impregnated materials on the market today. Various manufacturers assert that their dressings are the most effective and therefore should be preferentially employed. However, it is difficult to find a study that clearly identifies the most effective antimicrobial wound dressing...
July 2010: Wounds: a Compendium of Clinical Research and Practice
Jong Hoon Lee, Jeong Ja Kwak, Hee Bong Shin, Hae Won Jung, Young Koo Lee, Eui Dong Yeo, Seong Seok Yang
OBJECTIVE: Silver plays an important part in severe wound management, mainly by reducing microbial growth within dressed wounds and wound beds. However, it is unknown how silver-coated dressing materials affect diabetic wounds. The purpose of this study is to evaluate the efficacy of silver-containing dressing materials for the treatment of methicillin-resistant Staphylococcus aureus (MRSA)-infected wounds in streptozotocininduced diabetic rats. METHODS: Full-thickness skin defects were created on the backs of rats with streptozotocin (STZ)-induced diabetes (n = 108) and were infected with MRSA...
December 2013: Wounds: a Compendium of Clinical Research and Practice
Eui Dong Yeo, Su Ah Yoon, Seong Rok Oh, Young Suk Choi, Young Koo Lee
UNLABELLED: Silver-containing dressings are commonly used on healing wounds, including diabetic ulcers. Some studies have shown that dressing materials with silver have negative effects on wound healing, specifically, that the wound healing process is inhibited by deposited silver. Therefore, the authors treated wounds infected with methicillin-resistant Staphylococcus aureus (MRSA) in Sprague-Dawley (SD) rats and streptozotocin (STZ)-induced diabetic rats with silver dressings to evaluate the risks of silver...
April 2015: Wounds: a Compendium of Clinical Research and Practice
G Mosti, A Magliaro, V Mattaliano, P Picerni, N Angelotti
OBJECTIVE: The aim of the study was to compare the efficacy of a microorganism-binding (MB) dressing with a silver-containing hydrofiber (SCH) dressing in controlling the bacterial loads of heavily colonised or locally infected chronic venous leg ulcers, before surgical management with homologous skin grafts. METHOD: A randomised comparative single centre study recruited patients presenting with hard-to-heal critically colonised or locally infected leg ulcers, who could be treated with skin grafting...
March 2015: Journal of Wound Care
Jawal Said, Michael Walker, David Parsons, Paul Stapleton, Anthony E Beezer, Simon Gaisford
Broad-spectrum antimicrobial agents, such as silver, are increasingly being formulated into medicated wound dressings in order to control colonization of wounds by opportunistic pathogens. Medicated wound dressings have been shown in-vitro to be effective against planktonic cultures, but in-vivo bacteria are likely to be present in biofilms, which makes their control and eradication more challenging. Recently, a functional wound dressing (AQUACEL(®) Ag+ Extra™ (AAg + E)) has been developed that in addition to silver contains two agents (ethylenediaminetetraacetic acid (EDTA) and benzethonium chloride (BC)) designed to disrupt biofilms...
October 20, 2014: International Journal of Pharmaceutics
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