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Pancreaticoduodenectomy

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https://www.readbyqxmd.com/read/28919629/acinar-cell-carcinoma-of-the-pancreas-a-case-report
#1
S Mohammed, M M Chowdhury, A A Ullah, S M Towhid, S A Sobhan, I J Zeba, M M Haque, M T Islam, M Hussain, T K Roy, S R Russel, A M Chowdhury, M K Alam
Acinar cell carcinoma (ACC) of the pancreas is a very rare neoplasm. We report a case of pancreatic acinar cell carcinoma involving the uncinate process of the pancreas. A 45 year old man presented with a painful upper abdominal mass without any jaundice or weight loss. Computed Tomography (CT) and Magnetic Resonance Cholangio-Pancreatography (MRCP) indicated a mass lesion in the uncinate process of the pancreas. He underwent Whipple's procedure (Pancreaticoduodenectomy). Histological slides revealed features of Acinar cell carcinoma (ACC) in the uncinate process of the pancreas and a lymph node...
July 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28919282/impact-of-pancreaticoduodenal-arcade-dilation-on-postoperative-outcomes-after-pancreaticoduodenectomy
#2
Yusuke Nakayama, Motokazu Sugimoto, Tatsushi Kobayashi, Naoto Gotohda, Shinichiro Takahashi, Masahiko Kusumoto, Masaru Konishi
BACKGROUND: The aim of this study was to investigate the impact of pancreaticoduodenal arcade (PDA) dilation on postoperative outcomes after pancreaticoduodenectomy. METHODS: Consecutive patients submitted to pancreaticoduodenectomy between 2008 and 2016 underwent preoperative multi-detector computed tomography, the images of which were re-reviewed. The patients were categorized according to the grade of PDA dilation into 3 groups (remarkably-dilated, slightly-dilated, and non-dilated)...
September 14, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28914399/surgery-for-duodenal-gastrointestinal-stromal-tumors-a-single-center-experience
#3
Ping Chen, Tianqiang Song, Xin Wang, Hongyuan Zhou, Ti Zhang, Qiang Wu, Dalu Kong, Yunlong Cui, Huikai Li, Qiang Li
BACKGROUND: The duodenal gastrointestinal stromal tumors (GISTs) are an extremely rare subset of GISTs. The optimal surgical procedure remains not well defined. AIMS: We assessed the surgical approach and long-term outcomes of patients with duodenal GISTs who underwent limited resection (LR) versus pancreaticoduodenectomy (PD). METHODS: From November 2005 to January 2016, 64 consecutive patients with duodenal GISTs in a single center were retrospectively analyzed...
September 15, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28913712/surgical-site-infection-is-associated-with-tumor-recurrence-in-patients-with-extrahepatic-biliary-malignancies
#4
Stefan Buettner, Cecilia G Ethun, George Poultsides, Thuy Tran, Kamran Idrees, Chelsea A Isom, Matthew Weiss, Ryan C Fields, Bradley Krasnick, Sharon M Weber, Ahmed Salem, Robert C G Martin, Charles R Scoggins, Perry Shen, Harveshp D Mogal, Carl Schmidt, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Bas Groot Koerkamp, Shishir K Maithel, Timothy M Pawlik
BACKGROUND: Surgical site infections (SSI) are one of the most common complications after hepato-pancreato-biliary surgery. Infectious complications may lead to an associated immune-modulatory effect that inhibits the body's response to cancer surveillance. We sought to define the impact of SSI on long-term prognosis of patients undergoing surgical resection of extrahepatic biliary malignancies (EHBM). METHODS: Patients undergoing surgery for EHBM between 2000 and 2014 were identified using a large, multi-center, national cohort dataset...
September 14, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28912914/intraductal-ultrasonography-as-a-local-assessment-before-magnetic-compression-anastomosis-for-obstructed-choledochojejunostomy
#5
Hideaki Kawabata, Misuzu Hitomi, Naonori Inoue, Yukino Kawakatsu, Yuji Okazaki, Masatoshi Miyata
Magnetic compression anastomosis (MCA) has been developed as a non-surgical alternative treatment for biliary obstruction without serious complications. A 70-year-old woman who had undergone pancreaticoduodenectomy with modified Child reconstruction for pancreatic head cancer suffered from obstructed choledochojejunostomy with no recurrent findings 4 months after the operation. Cholangiography using the percutaneous transhepatic cholangiographic drainage (PTCD) and fluoroscopy revealed complete obstruction of the upper common bile duct, and the length of the obstruction was 7 mm...
August 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28912412/-a-case-of-advanced-neuroendocrine-cell-carcinoma-of-the-stomach-treated-with-s-1-and-cisplatin-chemotherapy
#6
Mikiko Sakuraya, Yoshimasa Shimizu, Nobuo Tachikawa, Hitoshi Hara, Masaki Ohashi, Tomoo Shatari, Masao Hori
A 69-year-old man presented to our hospital because of epigastric pain. A type 2 lesion was seen in the lesser curvature of the antrum of the stomach. A moderately differentiated adenocarcinoma(human epidermal growth factor receptor 2-negative) was diagnosed by biopsy. Abdominal computed tomography showed a mass shadow 52mm in diameter in the pyloric region invading the surrounding organs, but no evidence of distant metastasis. Chemotherapy with S-1 and cisplatin(SP therapy)was initiated because of a diagnosis of locally advanced gastric cancer...
September 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28911286/the-effect-of-a-surgery-specific-cardiac-output-guided-haemodynamic-algorithm-on-outcomes-in-patients-undergoing-pancreaticoduodenectomy-in-a-high-volume-centre-a-retrospective-comparative-study
#7
L Weinberg, J Banting, L Churilov, R L McLeod, K Fernandes, I Chao, T Ho, D Ianno, V Liang, V Muralidharan, C Christophi, M Nikfarjam
In this retrospective observational study performed in a high-volume hepatobiliary-pancreatic unit, we evaluated the effect of a surgery-specific goal-directed therapy (GDT) physiologic algorithm on complications and length of hospital stay. We compared patients who underwent pancreaticoduodenectomy with either a standardised Enhanced Recovery After Surgery program (usual care group), or a standardised Enhanced Recovery After Surgery program in combination with a surgery-specific cardiac output-guided algorithm (GDT group)...
September 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28904954/duodenum-preserving-resection-of-the-pancreatic-head-versus-pancreaticoduodenectomy-for-treatment-of-chronic-pancreatitis-with-enlargement-of-the-pancreatic-head-systematic-review-and-meta-analysis
#8
REVIEW
Yajie Zhao, Jianwei Zhang, Zhongmin Lan, Qinglong Jiang, Shuisheng Zhang, Yunmian Chu, Chengfeng Wang
The results of this meta-analysis show that DPPHR should be established as first-line treatment because of lower level of severe early postoperative complications, maintenance of endocrine pancreatic functions, shortening of postoperative hospitalization time, and increase of quality of life compared to pancreaticoduodenectomy.
2017: BioMed Research International
https://www.readbyqxmd.com/read/28902789/prognostic-significance-of-tumor-infiltrating-lymphocytes-in-patients-with-pancreatic-ductal-adenocarcinoma-treated-with-neoadjuvant-chemotherapy
#9
Reza Nejati, Jennifer B Goldstein, Daniel M Halperin, Hua Wang, Nazila Hejazi, Asif Rashid, Matthew H Katz, Jeffrey E Lee, Jason B Fleming, Jaime Rodriguez-Canales, Jorge Blando, Ignacio I Wistuba, Anirban Maitra, Robert A Wolff, Gauri R Varadhachary, Huamin Wang
OBJECTIVES: The aim of this study was to examine tumor-infiltrating lymphocytes (TILs) and their prognostic value in patients with pancreatic ductal adenocarcinoma (PDAC) after neoadjuvant therapy. METHODS: Intratumoral CD4, CD8, and FOXP3 lymphocytes were examined by immunohistochemistry using a computer-assisted quantitative analysis in 136 PDAC patients who received neoadjuvant therapy and pancreaticoduodenectomy. The results were correlated with clinicopathological parameters and survival...
October 2017: Pancreas
https://www.readbyqxmd.com/read/28902783/a-normal-preoperative-lipase-serum-level-is-an-easy-and-objective-risk-factor-of-pancreatic-fistula-after-pancreaticoduodenectomy
#10
Johan Gagnière, Adeline Abjean, Martin Franz, Ophélie Aumont, Bruno Pereira, Aurélien Dupré, Julie Veziant, Bertrand Le Roy, Louis Boyer, Denis Pezet, Emmanuel Buc
OBJECTIVES: The evaluation of the risk of postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy is crucial to optimize perioperative strategies. Many risk factors of POPF have been identified and were included in scores. Performances of these scores have to be improved because of the use of subjective and/or intraoperative factors. We tried to identify new risk factors of POPF that could improve the performance of validated scores. METHODS: We analyzed data from a prospective database of 191 consecutive patients who underwent a pancreaticoduodenectomy...
October 2017: Pancreas
https://www.readbyqxmd.com/read/28902764/development-of-a-prognostic-model-that-predicts-survival-after-pancreaticoduodenectomy-for-ampullary-cancer
#11
Michael Feretis, Tengyao Wang, Satheesh Iype, Adam Duckworth, Rebecca Brais, Bristi Basu, Neville V Jamieson, Emmanuel Huguet, Anita Balakrishnan, Asif Jah, Raaj K Praseedom, Simon J Harper, Siong-Seng Liau
OBJECTIVES: The aims of this study were to (i) identify independent predictors of survival after pancreaticoduodenectomy for ampullary cancer and (ii) develop a prognostic model of survival. METHODS: Data were analyzed retrospectively on 110 consecutive patients who underwent pancreaticoduodenectomy between 2002 and 2013. Subjects were categorized into 3 nodal subgroups as per the recently proposed nodal subclassification: N0 (node negative), N1 (1-2 metastatic nodes), or N2 (≥3 metastatic nodes)...
September 12, 2017: Pancreas
https://www.readbyqxmd.com/read/28898386/pancreaticojejunostomy-versus-pancreaticogastrostomy-reconstruction-for-the-prevention-of-postoperative-pancreatic-fistula-following-pancreaticoduodenectomy
#12
REVIEW
Yao Cheng, Marta Briarava, Mingliang Lai, Xiaomei Wang, Bing Tu, Nansheng Cheng, Jianping Gong, Yuhong Yuan, Pierluigi Pilati, Simone Mocellin
BACKGROUND: Pancreatoduodenectomy is a surgical procedure used to treat diseases of the pancreatic head and, less often, the duodenum. The most common disease treated is cancer, but pancreatoduodenectomy is also used for people with traumatic lesions and chronic pancreatitis. Following pancreatoduodenectomy, the pancreatic stump must be connected with the small bowel where pancreatic juice can play its role in food digestion. Pancreatojejunostomy (PJ) and pancreatogastrostomy (PG) are surgical procedures commonly used to reconstruct the pancreatic stump after pancreatoduodenectomy...
September 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28895142/randomized-clinical-trial-of-laparoscopic-versus-open-pancreatoduodenectomy-for-periampullary-tumours
#13
C Palanivelu, P Senthilnathan, S C Sabnis, N S Babu, S Srivatsan Gurumurthy, N Anand Vijai, V P Nalankilli, P Praveen Raj, R Parthasarathy, S Rajapandian
BACKGROUND: Laparoscopic resection as an alternative to open pancreatoduodenectomy may yield short-term benefits, but has not been investigated in a randomized trial. The aim of this study was to compare laparoscopic and open pancreatoduodenectomy for short-term outcomes in a randomized trial. METHODS: Patients with periampullary cancers were randomized to either laparoscopic or open pancreatoduodenectomy. The outcomes evaluated were hospital stay (primary outcome), and blood loss, radicality of surgery, duration of operation and complication rate (secondary outcomes)...
October 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28890820/a-margin-distance-analysis-of-the-impact-of-adjuvant-chemoradiation-on-survival-after-pancreatoduodenectomy-for-pancreatic-adenocarcinoma
#14
Lee M Ocuin, Jennifer L Miller-Ocuin, Mazen S Zenati, John A Vargo, Aatur D Singhi, Steven A Burton, Nathan Bahary, Melissa E Hogg, Herbert J Zeh, Amer H Zureikat
BACKGROUND: The role of adjuvant chemoradiotherapy (CRT) following pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma (PDA) remains controversial. Recent data suggest that increased margin clearance (MC: distance between tumor and cut surface) is associated with improved survival after PD, but the role of adjuvant CRT in patients with known MC is undefined. We sought to delineate the impact of adjuvant CRT on survival based on MC following PD. METHODS: Patients who underwent PD for PDA between 2002 and 2014 were retrospectively stratified into three groups based on MC: 0 mm, ≤1 mm, and >1 mm...
August 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28885506/the-theory-and-practice-of-pancreatic-surgery-in-france
#15
Olivier Farges, Noelle Bendersky, Stéphanie Truant, Jean Robert Delpero, François René Pruvot, Alain Sauvanet
OBJECTIVE: Measure the caseload of pancreatectomies that influences their short-term outcome, at a national level, and assess the applicability of a centralization policy. BACKGROUND: There is agreement that pancreatectomies should be centralized. However, previous studies have failed to accurately define a "high-volume" center. METHODS: French healthcare databases were screened to identify all adult patients who had elective pancreatectomies between 2007 and 2012...
September 6, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28884329/perioperative-mortality-following-oesophagectomy-and-pancreaticoduodenectomy-in-australia
#16
Sean S Davis, Wendy J Babidge, Andreas Kiermeier, R James Aitken, Guy J Maddern
INTRODUCTION: Oesophagectomy (OG) and pancreaticoduodenectomy (PD) remain associated with significant perioperative mortality rates (POMR). Improved outcomes in high-volume centres have led to these procedures being centralised in some countries. This retrospective, population-based cohort study was conducted to determine the Australian national, and state and territory based POMR associated with OG and PD, and assess trends over time. METHODS: Logistic regression analysis was performed using de-identified procedural data between 1 July 2005 and 30 June 2013 from the Australian Institute of Health and Welfare...
September 7, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28880931/restrictive-intraoperative-fluid-optimisation-algorithm-improves-outcomes-in-patients-undergoing-pancreaticoduodenectomy-a-prospective-multicentre-randomized-controlled-trial
#17
Laurence Weinberg, Damian Ianno, Leonid Churilov, Ian Chao, Nick Scurrah, Clive Rachbuch, Jonathan Banting, Vijaragavan Muralidharan, David Story, Rinaldo Bellomo, Chris Christophi, Mehrdad Nikfarjam
We aimed to evaluate perioperative outcomes in patients undergoing pancreaticoduodenectomy with or without a cardiac output goal directed therapy (GDT) algorithm. We conducted a multicentre randomised controlled trial in four high volume hepatobiliary-pancreatic surgery centres. We evaluated whether the additional impact of a intraoperative fluid optimisation algorithm would influence the amount of fluid delivered, reduce fluid related complications, and improve length of hospital stay. Fifty-two consecutive adult patients were recruited...
2017: PloS One
https://www.readbyqxmd.com/read/28877818/neuroendocrine-tumor-of-the-minor-duodenal-papilla-an-unusual-cause-of-pancreaticoduodenectomy
#18
Edoardo Virgilio, Giuseppe La Gumina, Francesca Tozzi, Yarilay Chacòn Marrero, Vincenzo Ziparo, Marco Cavallini
No abstract text is available yet for this article.
November 1, 2016: American Surgeon
https://www.readbyqxmd.com/read/28877110/predictors-of-intraoperative-pressure-injury-in-patients-undergoing-major-hepatobiliary-surgery
#19
Yan Chen, Li He, Wei Qu, Chen Zhang
PURPOSE: The purpose of this study was to identify risk factors associated with pressure injury (PI) development in patients undergoing major hepatobiliary surgery requiring general anesthesia. DESIGN: Retrospective medical review and analysis. SUBJECTS AND SETTING: Medical records from 803 patients undergoing hepatobiliary surgery from October 2015 to October 2016 were reviewed. The study setting was a 3400-bed military academic medical center in the northeast region of China...
September 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28876609/laparoscopic-pancreaticoduodenectomy-at-dr-george-mukhari-academic-hospital-a-case-report
#20
M Govender, C Kalenga, O Mongale, T Mosasi
BACKGROUND: The first total laparoscopic pancreaticoduodenectomy was performed in 1994 by Gagner and Pomp. Their comments coupled with the inherent technical difficulties stifled development of the technique. In the last decade there has been a renewed interest in the technique with high volume centres publishing large series. We present our experience with the first operation completed at Dr George Mukhari Academic Hospital. METHOD: Pre-operative CT confirmed a resectable head of pancreas mass...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
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