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Pancreaticoduodenectomy

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https://www.readbyqxmd.com/read/29152477/robotic-transduodenal-excision-of-ampullary-tumour
#1
EDITORIAL
Francis C H Wong, Eric C H Lai, Daniel T M Chung, Chung Ngai Tang
Ampullary tumours are uncommon lesions with potential risk of malignancy. The management is excision by either endoscopic ampullectomy, pancreaticoduodenectomy or transduodenal excision. Endoscopic ampullectomy offers a less invasive approach, whereas pancreaticoduodenectomy allows radical excision of the tumour. They both carry their own limitations. Transduodenal excision of ampullary tumour offers significantly lower risks with low recurrence rate, and can be offered for benign or early grade tumours. Limited cases of laparoscopic transduodenal excision of ampullary tumours were reported in the literature, probably due to the technical difficulties in performing the operation, especially during the reconstruction of the pancreaticobiliary ducts with the laparoscopic approach...
October 2017: Hepatobiliary Surgery and Nutrition
https://www.readbyqxmd.com/read/29151943/total-mesopancreas-excision-for-the-treatment-of-pancreatic-head-cancer
#2
Jingyong Xu, Xiaodong Tian, Yiran Chen, Yongsu Ma, Chang Liu, Long Tian, Jianwei Wang, Jianqiang Dong, Di Cui, Yang Wang, Weiguang Zhang, Yinmo Yang
Mesopancreas is a controversial structure. This study aimed to explore the anatomical characteristics of the mesopancreas, define the range of the total mesopancreas excision (TMpE), and evaluate the feasibility, safety and effectivity of TMpE in the treatment of pancreatic head cancer. The clinical and pathological data of 58 consecutive patients undergoing TMpE for pancreatic head carcinoma from January 2013 to December 2015 were analyzed prospectively. The perioperative morbidity, mortality and clinical outcomes of patients undergoing TMpE were compared with the patients undergoing conventional pancreaticoduodenectomy...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/29151507/successful-endoscopic-treatment-of-severe-pancreaticojejunostomy-strictures-by-puncturing-the-anastomotic-site-with-an-eus-guided-guidewire-a-report-of-two-cases
#3
Tatsuhide Nabeshima, Atsushi Kanno, Atsushi Masamune, Hiroki Hayashi, Seiji Hongo, Naoki Yoshida, Eriko Nakano, Shin Miura, Shin Hamada, Kazuhiro Kikuta, Kiyoshi Kume, Morihisa Hirota, Michiaki Unno, Tooru Shimosegawa
Pancreaticojejunostomy stricture (PJS) is a late complication of pancreaticoduodenectomy. The endoscopic treatment of PJS is very challenging due to the difficulty of locating the small anastomotic site and passing the stricture using a guidewire. We herein report two cases of severe PJS. These patients could not be treated using only double-balloon endoscopy or endoscopic ultrasound-guided puncture of the main pancreatic duct because of severe stenosis at the anastomotic site. However, we could treat them by the rendezvous technique using the rigid part of the guidewire to penetrate PJS...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29136998/early-drain-amylase-value-predicts-the-occurrence-of-pancreatic-fistula-after-pancreaticoduodenectomy
#4
Zhi Ven Fong, Carlos Fernández-Del Castillo
No abstract text is available yet for this article.
December 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29136997/early-drain-amylase-value-predicts-the-occurrence-of-pancreatic-fistula-after-pancreaticoduodenectomy
#5
Uirá Fernandes Teixeira, Marcos Bertozzi Goldoni, Fábio Luiz Waechter
No abstract text is available yet for this article.
December 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29133263/prospective-evaluation-of-pasireotide-in-patients-undergoing-pancreaticoduodenectomy-the-washington-university-experience
#6
Ismael Dominguez-Rosado, Ryan C Fields, Cheryl A Woolsey, Gregory Williams, Timothy A Horwedel, J Bart Rose, Chet W Hammill, Maria B Doyle, William C Chapman, Steven M Strasberg, William G Hawkins, Dominic E Sanford
BACKGROUND: Pasireotide is a newer generation somatostatin analogue which led to a significant reduction in pancreatic fistula after pancreatectomy in a single-center randomized controlled trial. We sought to determine if pasireotide reduces the incidence of pancreatic fistula and other complications following pancreaticoduodenectomy at our high volume center. STUDY DESIGN: All patients between April 2011 and January 2017 undergoing pancreaticoduodenectomy were prospectively followed and their complications graded using the Modified Accordion Grading System (MAGS) in our institutional complications database...
November 10, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29131967/prognostic-role-of-the-neutrophil-to-lymphocyte-ratio-nlr-in-patients-with-operable-ampullary-carcinoma
#7
Nebi Serkan Demirci, Gokmen Umut Erdem
Ampullary carcinoma or cancer of the ampulla of Vater is a rare malignancy with a high recurrence rate. Although cost-effective biomarkers, such as neutrophil-to-lymphocyte ratio (NLR), have been investigated in other cancers for predicting postoperative prognosis in patients, studies on the role of NLR in ampullary cancer are scarce. Here we aimed to evaluate the prognostic significance of the preoperative neutrophil-to-lymphocyte ratio (NLR) in patients with operable ampullary carcinoma. We retrospectively reviewed 87 patients who underwent pancreaticoduodenectomy for the treatment of ampullary carcinoma between December 1999 and April 2014...
November 13, 2017: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29117639/comparison-of-surgical-outcomes-between-open-and-robot-assisted-minimally-invasive-pancreaticoduodenectomy
#8
Hyeong Seok Kim, Youngmin Han, Jae Seung Kang, Hongbeom Kim, Jae Ri Kim, Wooil Kwon, Sun-Whe Kim, Jin-Young Jang
BACKGROUND: Robot surgery is new method that maintains advantages and overcomes disadvantages of conventional methods, even in pancreatic surgery. This study aimed to evaluate safety and benefits of robot-assisted minimally invasive pancreaticoduodenectomy (robot PD). METHODS: This study included 237 patients who underwent PD between 2015 and 2017. Demographics, surgical outcomes were evaluated. RESULTS: Fifty-one patients underwent robot PD and 186 underwent open PD...
November 8, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/29116490/impact-of-sarcopenic-obesity-on-failure-to-rescue-from-major-complications-following-pancreaticoduodenectomy-for-cancer-results-from-a-multicenter-study
#9
Nicolò Pecorelli, Giovanni Capretti, Marta Sandini, Anna Damascelli, Giulia Cristel, Francesco De Cobelli, Luca Gianotti, Alessandro Zerbi, Marco Braga
BACKGROUND: Failure to rescue (FTR) is a quality-of-care indicator in pancreatic surgery, but may also identify patients who may not tolerate major postoperative complications despite being treated with best available care. Previous studies found that high visceral adipose tissue-to-skeletal muscle ratio is associated with poor outcomes following pancreaticoduodenectomy (PD). The aim of the study is to assess the impact of sarcopenic obesity on occurrence of FTR from major complications in cancer patients undergoing PD...
November 7, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29100433/portal-vein-resection-and-reconstruction-with-artificial-blood-vessels-is-safe-and-feasible-for-pancreatic-ductal-adenocarcinoma-patients-with-portal-vein-involvement-chinese-center-experience
#10
Zhi-Bo Xie, Ji-Chun Gu, Yi-Fan Zhang, Lie Yao, Chen Jin, Yong-Jian Jiang, Ji Li, Feng Yang, Cai-Feng Zou, De-Liang Fu
Evidence shows that portal vein resection (PVR) increase the resectability but does little benefit to overall survival in all pancreatic ductal adenocarcinoma (PDAC) patients. But for patients with portal vein involvement, PVR is the only radical choice. But whether the PDAC patients with portal vein involvement would benefit from radical pancreaticoduodenectomy with PVR or not is controversial. All 204 PDAC patients with portal vein involvement were enrolled in this study [PVR group, n=106; surgical bypass (SB) group, n=52; chemotherapy group, n=46]...
September 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/29098452/synchronous-primary-gallbladder-and-pancreatic-cancer-associated-with-congenital-biliary-dilatation-and-pancreaticobiliary-maljunction
#11
Haruki Mori, Hiroya Iida, Hiromitsu Maehira, Naomi Kitamura, Tomoharu Shimizu, Masaji Tani
INTRODUCTION: Synchronous double cancer of the gallbladder and pancreas that is associated with congenital biliary dilatation (CBD) and pancreaticobiliary maljunction (PBM) is extremely rare. PBM is frequently reported in Asia, particularly in Japan. We report a surgical case of synchronous double cancer in a patient with primary gallbladder and pancreatic cancer. PRESENTATION OF CASE: A 72-year-old woman with epigastralgia underwent subtotal stomach-preserving pancreaticoduodenectomy and gallbladder bed resection for synchronous primary gallbladder and pancreatic head cancer...
November 2, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/29097875/trends-and-outcomes-of-pancreaticoduodenectomy-for-periampullary-tumors-a-25-year-single-center-study-of-1000-consecutive-cases
#12
Ayman El Nakeeb, Waleed Askar, Ehab Atef, Ehab El Hanafy, Ahmad M Sultan, Tarek Salah, Ahmed Shehta, Mohamed El Sorogy, Emad Hamdy, Mohamed El Hemly, Ahmed A El-Geidi, Tharwat Kandil, Mohamed El Shobari, Talaat Abd Allah, Amgad Fouad, Mostafa Abu Zeid, Ahmed Abu El Eneen, Nabil Gad El-Hak, Gamal El Ebidy, Omar Fathy, Ahmed Sultan, Mohamed Abdel Wahab
AIM: To evaluate the evolution, trends in surgical approaches and reconstruction techniques, and important lessons learned from performing 1000 consecutive pancreaticoduodenectomies (PDs) for periampullary tumors. METHODS: This is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period (1993-2002), middle period (2003-2012), and late period (2013-2017)...
October 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29095290/the-pancreatic-juice-length-in-the-stent-tube-as-the-predicting-factor-of-clinical-relevant-postoperative-pancreatic-fistula-after-pancreaticoduodenectomy
#13
Hangyan Wang, Dianrong Xiu, Ming Tao
Several risk factors for pancreatic fistula had been widely reported, but there was no research focusing on the exocrine output of remnant gland.During the study period of January 2015 to September 2016, 82 patients accepted pancreaticoduodenectomy (PD, end-to-end dunking pancreaticojejunostomy with internal stent tube). All the data were collected, including preoperative medical status, operative course, final pathology, gland texture, pancreatic duct diameter, size of the stent, length of pancreatic juice in the stent tube, width of the pancreatic stump, diameter of the jejunum and the status of postoperative pancreatic fistula (POPF)...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29094173/imaging-of-post-operative-pancreas-and-complications-after-pancreatic-adenocarcinoma-resection
#14
Nima Hafezi-Nejad, Elliot K Fishman, Atif Zaheer
Pancreatic ductal adenocarcinoma is one of the leading causes of cancer-related deaths. With surgical resection being the only definitive treatment, improvements in technique has led to an increase in number of candidates undergoing resection by inclusion of borderline resectable disease patients to the clearly resectable group. Post-operative complications associated with pancreaticoduodenectomy and distal pancreatectomy include delayed gastric emptying, anastomotic failures, fistula formation, strictures, abscess, infarction, etc...
November 1, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29081929/mucinous-cystic-neoplasms-in-male-patients-two-cases
#15
Shunsuke Tamura, Hirotaka Yamamoto, Shinichiro Ushida, Kazufumi Suzuki
Mucinous cystic neoplasms (MCNs) of the pancreas in male patients are very rare. Though few cases of MCNs in male patients have been reported, it is difficult to reveal them preoperatively. The first patient was a 50-year-old man and was incidentally found to have a cystic mass of 51 mm in the tail of the pancreas. We performed a distal pancreatectomy. The second patient was a 73-year-old man, incidentally found to have a cystic mass of 25 mm in diameter in the tail of the pancreas and a carcinoma of the bile duct...
October 3, 2017: Rare Tumors
https://www.readbyqxmd.com/read/29081374/enhanced-recovery-after-surgery-for-pancreaticoduodenectomy-review-of-current-evidence-and-trends
#16
REVIEW
Xiequn Xu, Chaoji Zheng, Yupei Zhao, Weiyun Chen, Yuguang Huang
Pancreaticoduodenectomy (PD) remains a morbid procedure. The use of Enhanced Recovery After Surgery (ERAS) pathways has proven to reduce care time and post-operative complications after colorectal surgery. There is a high potential for reducing morbidity associated with PD by utilizing ERAS. Guidelines for perioperative care after PD were published in 2013, but these recommendations could even change in one year. The purpose of this review is to examine the current evidence for ERAS in preoperative, intraoperative and post-operative setting of care for PD patients and to propose ERAS evidence-based protocol for patients undergoing PD...
October 25, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29081373/a-case-matched-comparison-study-of-total-pancreatectomy-versus-pancreaticoduodenectomy-for-patients-with-pancreatic-ductal-adenocarcinoma
#17
Junjie Xiong, Ailin Wei, Nengwen Ke, Du He, Selina Kwong Chian, Yi Wei, Weiming Hu, Xubao Liu
BACKGROUND: Total pancreatectomy (TP) is considered a viable option in some selected patients with pancreatic ductaladenocarcinoma (PDAC). The aim of this study was to compare the clinical outcomes between TP and pancreaticoduodenectomy (PD) in patients with PDAC. MATERIALS AND METHODS: A total of 375 patients were selected from our center's database in China and classified into two groups: the PD group (n = 325) and the TP group (n = 50). A matched-pair analysis of the patients was conducted with a ratio of 1:1...
October 30, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29078644/technical-considerations-for-the-fully-robotic-pancreaticoduodenectomy
#18
Daniel Galvez, Rebecca Sorber, Ammar A Javed, Jin He
Minimally invasive surgery, including robotic surgery, has become the standard of care for many abdominal procedures. However, the technical complexity associated with pancreaticoduodenectomy (PD) due to the anatomic location and oncologic characteristics of pancreatic tumors has hindered the widespread application of minimally invasive techniques to this procedure. Recent studies have reported that for experienced surgeons, the application of robotic techniques to PD is associated with equivalent oncologic outcomes and rates of complication when compared to an open operation, and may be associated with accelerated surgical recovery...
2017: J Vis Surg
https://www.readbyqxmd.com/read/29075846/postoperative-outcome-and-quality-of-life-after-surgery-for-fap-associated-duodenal-adenomatosis
#19
Petra Ganschow, Thilo Hackert, Marcel Biegler, Pietro Contin, Ulf Hinz, Markus W Büchler, Martina Kadmon
INTRODUCTION: Prophylactic colon surgery has increased life expectancy of familial adenomatous polyposis patients. Extracolonic manifestations are life limiting, above all duodenal adenomas. Severe duodenal adenomatosis or cancer may necessitate pancreas-preserving total duodenectomy or partial pancreatico-duodenectomy, mostly after previous proctocolectomy and often after limited local resections of duodenal adenomas. Scarce information on long-term postoperative outcome and quality of life after surgery for duodenal adenomatosis is available...
October 26, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29067580/comparison-of-laparoscopic-to-open-pancreaticoduodenectomy-in-elderly-patients-with-pancreatic-adenocarcinoma
#20
Brandon C Chapman, Csaba Gajdos, Patrick Hosokawa, William Henderson, Alessandro Paniccia, Douglas M Overbey, Ana Gleisner, Richard D Schulick, Martin D McCarter, Barish H Edil
INTRODUCTION: The purpose of the study is to compare perioperative and survival outcomes in elderly patients undergoing laparoscopic pancreaticoduodenectomy (LPD) to those undergoing open pancreaticoduodenectomy (OPD). METHODS: Patients aged ≥ 75 years with pancreatic adenocarcinoma undergoing LPD or OPD were identified from the NCDB (2010-2013). Baseline characteristics and perioperative outcomes were compared using a χ (2) and Student's t test. The Kaplan-Meier method was used to generate survival curves, and differences were tested using a log-rank test...
October 24, 2017: Surgical Endoscopy
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