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Ryota Matsuki, Masanori Sugiyama, Shinya Yoshiike, Junji Shibahara, Masaharu Kogure, Masaaki Yokoyama, Yutaka Suzuki, Nobutsugu Abe, Tadahiko Masaki, Toshiyuki Mori
A 72-year-old woman with advanced ascending colon cancer and an intraductal papillary mucinous neoplasm (IPMN) of the pancreatic head was treated by right hemicolectomy (RHC) and pylorus-preserving pancreaticoduodenectomy (PpPD). Adjuvant chemotherapy was not administered. Multimodal examinations at 5 months after surgery detected a solitary metastatic liver tumor derived from cancer of the ascending colon. Liver resection proceeded at 7 months after the first surgery. A pathological study of a surgical specimen of the liver identified a necrotic nodule that did not contain viable tumor cells...
March 15, 2018: Clinical Journal of Gastroenterology
Margareta Heby, Sebastian Lundgren, Björn Nodin, Jacob Elebro, Jakob Eberhard, Karin Jirström
BACKGROUND: Periampullary adenocarcinomas, including pancreatic cancer, are a heterogeneous group of tumors with poor prognosis, where classification into intestinal type (I-type) or pancreatobiliary type (PB-type) is a relevant prognostic factor. The clinical significance of deficient mismatch repair (dMMR) in periampullary adenocarcinoma is comparatively unexplored. Herein, we examined the associations of MMR immunophenotype with long-term survival in patients with resected periampullary adenocarcinoma, with particular reference to morphology and adjuvant treatment response...
March 14, 2018: Journal of Translational Medicine
N S Demirci, N Y Ozdemir, G U Erdem, Y Bozkaya, O Yazici, N Zengin
AIM: To emphasize the significance of the platelet-to-lymphocyte ratio (PLR) in estimating the postoperative prognosis or survival measures in patients with carcinoma of the ampulla of Vater. METHODS: We retrospectively reviewed 82 patients, who underwent pancreaticoduodenectomy for ampullary carcinoma between July 2001 and April 2014. We investigated the predictive significance of the preoperative PLR for disease-free survival (DFS) or overall survival (OS). The possible correlations between the PLR and clinical or pathological features were also evaluated...
2018: Bratislavské Lekárske Listy
Dominic Cheong, Seoung Yoon Rho, Ji Hong Kim, Chang Moo Kang, Woo Jung Lee
Renal cell carcinoma is the most common primary renal neoplasm in adults. Although renal cell carcinoma is known to spread to unusual sites, the ampulla of Vater is considered a rare site for metastasis. Here we present a case of renal cell carcinoma metastasized to the ampulla of Vater along with literature review. A 62-year-old Korean male had a history of hypertension and right-sided renal cell carcinoma diagnosed in September 2004, for which he underwent right radical nephrectomy in October 2004. The patient eventually underwent laparoscopic pylorus-preserving total pancreaticoduodenectomy in January 2017...
February 2018: Annals of Hepato-Biliary-Pancreatic Surgery
Kanefumi Yamashita, Daisuke Kato, Takamitsu Sasaki, Hironari Shiwaku, Fuminori Ishii, Shigetoshi Naito, Yuichi Yamashita, Suguru Hasegawa
BACKGROUND: Appropriate bacterial infection control in the perioperative period of a pancreaticoduodenectomy (PD) is important to prevent and manage serious complications including postoperative pancreatic fistula (POPF). In the present study, the clinical impact of bacterial contamination of intra-abdominal discharge on the rate of POPF after PD was analysed retrospectively. MATERIALS AND METHODS: The data for 82 consecutive patients who had undergone PD at our hospital between January 2009 and July 2014 were retrospectively analysed to review patient characteristics and perioperative and postoperative parameters...
March 9, 2018: International Journal of Surgery
Jihion Yu, Hyungseok Seo, Hong-Kyoon Kim, Song Cheol Kim, Young-Kug Kim
Laparoscopic pylorus-preserving pancreaticoduodenectomy (LPPPD) is less invasive than open pylorus-preserving pancreaticoduodenectomy. However, LPPPD has a long operation time with pneumoperitoneum, which may affect the postoperative pulmonary complications (PPCs). We retrospectively evaluated the incidence of PPCs and their risk factors in LPPPD. In 191 patients who underwent LPPPD, the incidence of PPCs was 28.8% (n=55). Multivariate logistic regression analysis revealed that the risk factors for PPCs were male sex [odds ratio (OR), 2...
March 9, 2018: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
Peter J Lee, Amareshwar Podugu, Dong Wu, Arier C Lee, Tyler Stevens, John A Windsor
BACKGROUND: Controversy remains about the best pre-operative management of jaundice in patients with resectable pancreatic head cancer (RPC) undergoing planned pancreaticoduodenectomy (PD). OBJECTIVE: The aim of this study was to compare rates of post-operative complications in patients undergoing four pre-operative approaches (POA): preoperative biliary drainage with plastic stent (PBD-PS), metal stent (PBD-MS), and percutaneous transhepatic drain (PBD-PT), or no pre-operative biliary drainage (NPBD)...
March 8, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
Yuichi Hosokawa, Yuichi Nagakawa, Yatsuka Sahara, Chie Takishita, Tetsushi Nakajima, Yosuke Hijikata, Hiroaki Osakabe, Tomoki Shirota, Kazuhiro Saito, Hiroshi Yamaguchi, Keiichiro Inoue, Kenji Katsumata, Takayoshi Tsuchiya, Atsushi Sofuni, Takao Itoi, Akihiko Tsuchida
BACKGROUND/PURPOSE: The proximal jejunal vein which branches from the dorsal side of the superior mesenteric vein (SMV) usually drains the inferior pancreatoduodenal veins (IPDVs) and contacts the uncinate process of the pancreas. We focused on this vein, termed the proximal dorsal jejunal vein (PDJV), and evaluated the anatomical classification of the PDJV and surgical outcomes in patients with pancreatic ductal adenocarcinoma (PDAC) with PDJV involvement (PDJVI). METHODS: The jejunal veins that branch from the dorsal side of the SMV above the inferior border of the duodenum are defined as PDJVs...
March 8, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Russell C Kirks, Allyson Cochran, T Ellis Barnes, Keith Murphy, Erin H Baker, John B Martinie, David A Iannitti, Dionisios Vrochides
BACKGROUND: The American College of Surgeons (ACS) Surgical Risk Calculator predicts postoperative risk based on preoperative variables. The ACS model was compared to an institution-specific risk calculator for pancreaticoduodenectomy (PD). METHODS: Observed outcomes were compared with those predicted by the ACS and institutional models. Receiver operating characteristic (ROC) analysis evaluated the models' predictive ability. Institutional models were evaluated with retrospective and prospective internal validation...
February 17, 2018: American Journal of Surgery
Thomas Godet, Renaud Guérin, Camille Verlhac, Sophie Cayot, Matthieu Jabaudon, Jean-Etienne Bazin, Emmanuel Futier, Jean-Michel Constantin
No abstract text is available yet for this article.
April 2018: Annals of Surgery
Yoichi Koga, Akihiko Soyama, Amane Kitasato, Mitsuhisa Takatsuki, Susumu Eguchi
No abstract text is available yet for this article.
2018: ACG Case Reports Journal
Kenji Sakai, Tomohiro Mizuno, Taiju Watanabe, Eiki Nagaoka, Keiji Oi, Masafumi Yashima, Tsuyoshi Hachimaru, Hidehito Kuroki, Tatsuki Fujiwara, Masashi Takeshita, Minoru Tanabe, Hirokuni Arai
BACKGROUND: The right gastroepiploic artery (GEA) is utilized as an excellent in-situ arterial graft conduit to right coronary artery territory for coronary artery bypass grafting (CABG). However, there remains great concerns regarding the management of patients with a patent in-situ GEA during abdominal surgery following CABG. METHODS: From 1995 to 2016, GEA was used for CABG in 278 patients at our institution. Of the patients, 14 abdominal surgeries were performed for subsequent abdominal diseases in 11 patients with a patent in-situ GEA for CABG...
March 3, 2018: Annals of Thoracic Surgery
R Ballarin, P Magistri, G Tarantino, G Assirati, A Pecchi, G P Guerrini, F Di Benedetto
No abstract text is available yet for this article.
February 2018: European Review for Medical and Pharmacological Sciences
Sara L Zettervall, Tammy Ju, Jeremy L Holzmacher, Lisbi Rivas, Paul P Lin, Khashayar Vaziri
BACKGROUND: Post-operative pancreatic fistulas remain a significant source of morbidity following pancreatic surgery. Few studies have evaluated the effect of neoadjuvant chemotherapy and radiation on this adverse outcome. This study aims to evaluate the effects of neoadjuvant therapy on 30-day morbidity and mortality following pancreaticoduodenectomy. STUDY DESIGN: A retrospective analysis was performed utilizing the targeted pancreas module of the National Surgical Quality Improvement Project (NSQIP) from 2014 to 2015 for patients undergoing pancreaticoduodenectomy with pancreaticojejunal reconstruction...
March 2, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Debang Li, Xiaoying Si, Tao Wan, Yanming Zhou
PURPOSE: The aim of this study was to evaluate the safety and efficacy of en bloc right hemicolectomy with pancreaticoduodenectomy (RHCPD) for locally advanced right-sided colon cancer (LARCC). METHOD: A pooled data analysis was performed on individual patients identified from the literature and the authors' institutions. The short- and long-term outcomes were assessed. RESULTS: Recruited in this study were 81 LARCC patients undergoing RHCPD, including 75 patients reported in the literature and 6 patients from our own institutions...
March 2, 2018: International Journal of Colorectal Disease
Olaya I Brewer Gutierrez, Shayan S Irani, Saowanee Ngamruengphong, Hanaa D Aridi, Rastislav Kunda, Ali Siddiqui, Markus Dollhopf, Jose Nieto, Yen-I Chen, Nadav Sahar, Majidah A Bukhari, Omid Sanaei, Marcia I Canto, Vikesh K Singh, Richard Kozarek, Mouen A Khashab
BACKGROUND:  Afferent loop syndrome (ALS) is traditionally managed surgically and, more recently, endoscopically. The role of endoscopic ultrasound-guided entero-enterostomy (EUS-EE) has not been well described. The aim of this study was to assess the technical and clinical success and safety of EUS-EE. METHODS:  This was a multicenter, retrospective series at six centers in patients with ALS treated by EUS-EE. Data on patients treated with enteroscopy-assisted luminal stenting (EALS) at a single center were also collected...
March 2, 2018: Endoscopy
Yu Jiang, Jia-Bin Jin, Qian Zhan, Xia-Xing Deng, Cheng-Hong Peng, Bai-Yong Shen
BACKGROUND: The purpose of this study was to compare short- and long-term outcomes of modified robot-assisted duodenum-preserving pancreatic head resection (RA-DPPHR) versus robot-assisted pancreaticoduodenectomy (RA-PD). METHODS: Matched for age, sex, ASA classification, tumour size, history of abdominal surgery and pathological type, 34 patients undergoing RA-DPPHR and 34 patients undergoing RA-PD between January 2010 and December 2016 were retrospectively analyzed...
March 2, 2018: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
S K Kamarajah
INTRODUCTION: This study aimed to evaluate the impact of adjuvant radiotherapy in patients undergoing pancreaticoduodenectomy (PD) for ampullary adenocarcinoma. METHODS: Using the Surveillance, Epidemiology, and End Results, patients with non-metastatic ampullary adenocarcinoma between 2004 and 2013 were identified. Cancer-specific survival and overall survival were estimated using Kaplan-Meier and Cox regression to obtain adjusted hazard ratio of survival. RESULTS: In this study, 1106 patients with ampullary adenocarcinoma were identified, of which 27% received adjuvant radiotherapy and the remaining 73% (803/1106) patients did not receive any adjuvant radiotherapy...
March 1, 2018: Clinical & Translational Oncology
Yosuke Inoue, Akio Saiura, Yu Takahashi
In the original article, the captions for Figs. 2 and 3 were erroneously interchanged. The original article has been corrected.
March 1, 2018: World Journal of Surgery
Gian Luca Baiocchi, Edoardo Rosso, Andrea Celotti, Giuseppe Zimmiti, Alberto Manzoni, Marco Garatti, Guido Tiberio, Nazario Portolani
To analyze the clinical outcomes of patients undergoing minimally invasive surgery for pancreatic neoplasms, in two medium-volume centers in Northern Italy, a retrospective chart review was performed in the operative registries, searching for patients who had undergone pancreatic surgery via laparoscopy, irrespective of the final pathological nature of the resected neoplasm. For each case, a standard data extraction form was completed and the following data was extracted: age and sex, type of resection, estimated blood loss, length of the operation, number of harvested nodes, post-operative pancreatic fistula, major post-operative complications, mortality and final pathological diagnosis...
February 28, 2018: Updates in Surgery
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