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https://www.readbyqxmd.com/read/27912751/anti-aging-and-tyrosinase-inhibition-effects-of-cassia-fistula-flower-butanolic-extract
#1
Pornngarm Limtrakul, Supachai Yodkeeree, Pilaiporn Thippraphan, Wanisa Punfa, Jatupol Srisomboon
BACKGROUND: Natural products made from plant sources have been used in a variety of cosmetic applications as a source of nutrition and as a whitening agent. The flowers of Cassia fistula L, family Fabaceae, have been used as a traditional medicine for skin diseases and wound healing and have been reported to possess anti-oxidant properties. The anti-aging effect of C. fistula flower extract on human skin fibroblast was investigated. METHODS: The butanolic extraction of C...
December 3, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27893508/best-practices-for-pressure-ulcer-prevention-in-the-burn-center
#2
Julia Warner, Mary Ann Raible, Gina Hajduk, Jacqueline Collavo
The State of Pennsylvania Hospital Engagement Network, in collaboration with a hospital system in Southwestern Pennsylvania, established a goal of reducing hospital-acquired pressure ulcers by 20%. A 6-month unfavorable trend of nurse-sensitive clinical indicators called for immediate process improvement. A retrospective chart review resulted in identification of predominant risk factors placing the burn patient at high risk for pressure ulcer formation. Implementations of pressure ulcer prevention measures were inconsistent...
January 2017: Critical Care Nursing Quarterly
https://www.readbyqxmd.com/read/27863057/platelet-rich-plasma-based-bioactive-membrane-as-a-new-advanced-wound-care-tool
#3
Raffaele Spanò, Anita Muraglia, Maria R Todeschi, Marta Nardini, Paolo Strada, Ranieri Cancedda, Maddalena Mastrogiacomo
Chronic skin ulcers, consequence of diabetes and other pathological conditions, heavily compromise the patients' life quality and represent a high and constantly growing cost for National Health Services. Autologous Platelet Rich Plasma (PRP), has been proposed to treat these lesions. The absence of guidelines for the PRP production and the need of a fresh preparation for each treatment lead us to develop a protocol for the production of an allogenic PRP based bioactive membrane (BAM), standardized for platelet concentration and growth factor release...
November 13, 2016: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/27843333/water-soluble-egg-membrane-enhances-the-immunoactivating-properties-of-an-aloe-vera-based-extract-of-nerium-oleander-leaves
#4
Kathleen F Benson, Robert A Newman, Gitte S Jensen
OBJECTIVE: To evaluate a blend of two natural ingredients on immune parameters relevant for their current topical use and potential support of microcirculation in skin tissue. MATERIALS AND METHODS: A blend (BL) of Aloe vera-based Nerium oleander extract (NAE-8i, oleandrin-free) and hydrolyzed water-soluble egg membrane (WSEM) was applied to human whole-blood cultures for 24 hours, with each separate ingredient serving as a control. Immune-cell subsets were analyzed for expression levels of the activation markers CD69 and CD25...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/27825971/eicosanoids-emerging-contributors-in-stem-cell-mediated-wound-healing
#5
REVIEW
Elizabeth Berry, Yanzhou Liu, Li Chen, Austin M Guo
Eicosanoids are bioactive lipid products primarily derived from the oxidation of arachidonic acid (AA). The individual contributions of eicosanoids and stem cells to wound healing have been of great interest. This review focuses on how stem cells work in concert with eicosanoids to create a beneficial environment in the wound bed and in the promotion of wound healing. Stem cells contribute to wound healing through modulating inflammation, differentiating into skin cells or endothelial cells, and exerting paracrine effects by releasing various potent growth factors...
November 5, 2016: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/27815078/ziziphora-tenuior-l-essential-oil-from-dana-biosphere-reserve-southern-jordan-chemical-characterization-and-assessment-of-biological-activities
#6
M S Abu-Darwish, C Cabral, M J Gonçalves, C Cavaleiro, M T Cruz, M Paoli, F Tomi, T Efferth, L Salgueiro
ETHNOPHARMACOLOGIC RELEVANCE: Ziziphora tenuior L. (Lamiaceae) is a medicinal plant in Jordan, which is included in various antimicrobial, antiseptic, expectorant and wound healing preparations. It is used for the treatment of cough, stomach ache, dysentery, fever, uterus infection, gut inflammation and painful menstruation. AIM OF THE STUDY: The aim of this study was to assess, for the first time, the chemical composition of the essential oil of Z. tenuior originated from southern Jordan and its antifungal effects against several yeasts...
November 1, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27800466/emerging-carbapenem-resistant-pseudomonas-aeruginosa-isolates-carrying-blaimp-among-burn-patients-in-isfahan-iran
#7
Mohsen Radan, Rezvan Moniri, Ahmad Khorshidi, Hamidreza Gilasi, Zohreh Norouzi, Fahimeh Beigi, Yasaman Dasteh Goli
BACKGROUND: Metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa is a significant pathogen in burn patients. OBJECTIVES: The aim of this study was to determine the prevalence of carbapenem-resistant P. aeruginosa isolates, including those resistant to imipenemase (IMP), in a burn unit in Isfahan, Iran. PATIENTS AND METHODS: One hundred and fifty P. aeruginosa isolates from burn patients were tested for antibiotic susceptibility by the disc diffusion method in accordance with CLSI guidelines...
September 2016: Archives of Trauma Research
https://www.readbyqxmd.com/read/27800133/staphylococcal-cassette-chromosome-mec-types-among-methicillin-resistant-staphylococcus-aureus-in-northern-iran
#8
Akram Taherirad, Roghayeh Jahanbakhsh, Fatemeh Shakeri, Shaghayegh Anvary, Ezzat Allah Ghaemi
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of nosocomial and community-acquired infections around the world. Staphylococcal cassette chromosome mec (SCCmec) typing methods are often used to study MRSA molecular epidemiology. OBJECTIVES: The current study was designed to explore the distribution profiles of different SCCmec types among methicillin-resistant S. aureus strains isolated from hospitals in Gorgan, in northern Iran, and to correlate the types into observed bacterial virulence factors...
August 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/27788747/the-risk-of-bacterial-infection-after-tattooing
#9
Ralf Dieckmann, Ides Boone, Stefan O Brockmann, Jens A Hammerl, Annette Kolb-Mäurer, Matthias Goebeler, Andreas Luch, Sascha Al Dahouk
BACKGROUND: Tattooing is a globally growing trend. Overall prevalence among adults in industrialized countries is around 10-20%. Given the high and increasing numbers of tattooed people worldwide, medical and public health implications emerging from tattooing trends require greater attention not only by the public, but also by medical professionals and health policy makers. METHODS: We performed a systematic review of the literature on tattooassociated bacterial infections and bacterial contamination of tattoo inks...
October 7, 2016: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/27777596/acmella-oleracea-and-achyrocline-satureioides-as-sources-of-natural-products-in-topical-wound-care
#10
Lais Thiemi Yamane, Eneida de Paula, Michelle Pedroza Jorge, Verônica Santana de Freitas-Blanco, Ílio Montanari Junior, Glyn Mara Figueira, Luís Adriano Anholeto, Patricia Rosa de Oliveira, Rodney Alexandre Ferreira Rodrigues
The Brazilian forests have one of the world's biggest biodiversities. Achyrocline satureioides (macela) and Acmella oleracea (jambu) are native species from Brazil with a huge therapeutic potential, with proved anti-inflammatory and anesthetic action, respectively. The jambu's crude extract after depigmentation with activated charcoal and macela's essential oil were incorporated in a film made with hydroxyethyl cellulose. Those films were evaluated by mechanical test using a texturometer and anti-inflammatory and anesthetic activities by in vivo tests: wound healing and antinociceptive...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27764189/human-serum-albumin-hsa-suppresses-the-effects-of-glycerol-monolaurate-gml-on-human-t-cell-activation-and-function
#11
Michael S Zhang, Jon C D Houtman
Glycerol monolaurate (GML) is a monoglyceride with well characterized anti-microbial properties. Because of these properties, GML is widely used in food, cosmetics, and personal care products and currently being tested as a therapeutic for menstrual associated toxic shock syndrome, superficial wound infections, and HIV transmission. Recently, we have described that GML potently suppresses select T cell receptor (TCR)-induced signaling events, leading to reduced human T cell effector functions. However, how soluble host factors present in the blood and at sites of infection affect GML-mediated human T cell suppression is unknown...
2016: PloS One
https://www.readbyqxmd.com/read/27744069/model-polymer-system-for-investigating-the-generation-of-hydrogen-peroxide-and-its-biological-responses-during-the-crosslinking-of-mussel-adhesive-moiety
#12
Hao Meng, Yuan Liu, Bruce P Lee
: Mussel adhesive moiety, catechol, has been utilized to design a wide variety of biomaterials. However, the biocompatibility and biological responses associated with the byproducts generated during the curing process of catechol has never been characterized. An in situ curable polymer model system, 4-armed polyethylene glycol polymer end-capped with dopamine (PEG-D4), was used to characterize the production of hydrogen peroxide (H2O2) during the oxidative crosslinking of catechol. Although PEG-D4 cured rapidly (under 30s), catechol continues to polymerize over several hours to form a more densely crosslinked network over time...
October 12, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27717144/an-ex-vivo-porcine-skin-model-to-evaluate-pressure-reducing-devices-of-different-mechanical-properties-used-for-pressure-ulcer-prevention
#13
Ching-Yan C Yeung, David F Holmes, Helen A Thomason, Christian Stephenson, Brian Derby, Matthew J Hardman
Pressure ulcers are complex wounds caused by pressure- and shear-induced trauma to skin and underlying tissues. Pressure-reducing devices, such as dressings, have been shown to successfully reduce pressure ulcer incidence, when used in adjunct to pressure ulcer preventative care. While pressure-reducing devices are available in a range of materials, with differing mechanical properties, understanding of how a material's mechanical properties will influence clinical efficacy remains limited. The aim of this study was to establish a standardised ex vivo model to allow comparison of the cell protection potential of two gel-like pressure-reducing devices with differing mechanical properties (elastic moduli of 77 kPa v 35 kPa)...
September 26, 2016: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/27701127/efficacy-and-safety-of-a-novel-autologous-wound-matrix-in-the-management-of-complicated-chronic-wounds-a-pilot-study
#14
Igal Kushnir, Alon Kushnir, Thomas E Serena, Doron Garfinkel
INTRODUCTION: The objective of this pilot study was to evaluate the efficacy and safety of a novel method using an autologous whole blood clot formed with the RedDress Wound Care System (RD1, RedDress Ltd, Israel), a provisional whole blood clot matrix used in the treatment of chronic wounds of various etiologies. METHODS AND MATERIALS: Patients were treated at the bedside with the whole blood clot matrix. Blood was withdrawn from each patient using citrate, mixed with a calcium gluconate/kaolin suspension, and injected into an RD1 clotting tray...
September 2016: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/27680011/-wound-management-with-enzyme-alginogels-expert-consensus
#15
R Strohal, B Assenheimer, M Augustin, G Hämmerle, S Läuchli, B Pundt, G Stern, M Storck, C Ulrich
BACKGROUND: The challenges of modern wound management, such as the treatment of chronic wounds and their phase-specific handling, are demanding and require optimally adapted therapeutic measures. The principles of moist wound care as well as an adequate debridement have priority here. To support these necessary measures, different options are available, e.g., a new product group operating across several wound phases. OBJECTIVE: A new treatment principle in modern wound management based on an expert consensus is presented...
September 28, 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/27660723/application-of-autologous-platelet-rich-plasma-prp-on-wound-healing-after-caesarean-section-in-high-risk-patients
#16
Afsaneh Tehranian, Bahareh Esfehani-Mehr, Reihaneh Pirjani, Negar Rezaei, Somaye Sadat Heidary, Mahdi Sepidarkish
BACKGROUND: Platelet-rich plasma (PRP) is a human plasma product enriched by platelets, growth factors, and fibrinogen with high hemostatic and healing properties. OBJECTIVES: The aim of this study was to evaluate the effect of autologous PRP on wound healing in high-risk women undergoing cesarean sections. PATIENTS AND METHODS: In this balanced, randomized, and controlled trial, 140 patients were admitted to Arash women's hospital, Tehran, Iran from May of 2013 to November of 2014 for elective cesarean surgery...
July 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/27658997/controlling-intraoperative-hemorrhage-during-burn-surgery-a-prospective-randomized-trial-comparing-nustat-%C3%A2-hemostatic-dressing-to-the-historic-standard-of-care
#17
C Caleb Butts, Kelly Bose, M Amin Frotan, Juvonda Hodge, Salil Gulati
INTRODUCTION: One of the primary intraoperative challenges during burn surgery is to adequately excise the burn while avoiding massive hemorrhage. This has become increasingly important, as we see more burn patients that are older and with more medical comorbidities. While adequate excision down to healthy tissues for deep burns is essential for skin graft to take, it also leads to active bleeding that can be a challenge to control. Good hemostasis is imperative as a hematoma is the most common cause of graft loss...
September 19, 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/27622980/-when-to-worry-about-before-a-vascular-chronic-leg-ulcer
#18
I Lazareth
Leg ulcers are a chronic condition. Healing can be long for venous ulcers and the risk of complications is significant. Infection is the most severe complication and can occur in the form of easily diagnosed acute bacterial dermohypodermitis that generally responds well to antibiotic treatment if given at an appropriate dose or in the form of localized infection that is more difficult to diagnosis. Indeed, no consensus has been reached in the literature on the clinical criteria to retain for the diagnosis of localized infection...
September 2016: Journal des Maladies Vasculaires
https://www.readbyqxmd.com/read/27615046/-economic-effect-of-home-health-care-services-for-community-dwelling-vulnerable-populations
#19
Eunhee Lee, Jinhyun Kim
PURPOSE: In this study the costs and benefits of a home health care program were examined to evaluate the economic feasibility of the program. METHODS: The study participants included 349 patients in the community who had been registered at a home health care center for 5 years. The costs and benefits of the program were analyzed using performance data and health data. The benefits were classified as the effects of pressure ulcer care, skin wound care and catheters management...
August 2016: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/27611017/leptospermum-honey-for-wound-care-in-an-extremely-premature-infant
#20
Media Esser
BACKGROUND/INTRODUCTION TO CASE: Neonatal wound care is challenging due to the fragility and vulnerable skin structure. Neonates are often left susceptible to the forces of their environment, leaving them open to infection when skin injury occurs. Leptospermum honey has been used successfully in adult patients, with evidence lacking in the neonatal population. This case demonstrates the management of a difficult-to-heal wound in a 23-week gestation infant. PURPOSE: Selecting the proper treatment and products for wound healing is challenging, with little evidence-based research available for the treatment of neonatal wounds...
September 8, 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
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