José Weverton Almeida-Bezerra, Rafael Pereira da Cruz, Raimundo Luiz Silva Pereira, Viviane Bezerra da Silva, Daniele de Oliveira Bezerra de Sousa, João Xavier Da Silva Neto, Larissa Alves Lopes de Souza, Nadine Monteiro Salgueiro Araújo, Rafael Guimarães Gomes Silva, Daniel Luna Lucetti, Henrique Douglas Melo Coutinho, Maria Flaviana Bezerra Morais-Braga, Antônio Fernando Morais de Oliveira
Caryocar coriaceum, commonly known as 'pequi', is a medicinal species used traditionally for the herbal treatment of infectious and parasitic diseases in the Brazilian Northeast region. In this study, we investigated whether the fruits of C. coriaceum have bioactive chemical constituents against etiological agents of infectious diseases. The methanolic extract of the internal mesocarp of the fruits of C. coriaceum (MECC) was chemically analyzed and evaluated for its antimicrobial and drug-enhancing activity against multidrug-resistant pathogenic bacteria (Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus), and Candida spp...
June 15, 2023: Microbial Pathogenesis