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https://www.readbyqxmd.com/read/28651355/evaluation-of-welfare-parameters-in-laying-hens-on-the-basis-of-a-bavarian-survey
#1
H Louton, S M Bergmann, E Rauch, C Liebers, S Reese, M H Erhard, C Hoeborn, A Schwarzer
Health issues like infestation with poultry red mite (Dermanyssus gallinae) and behavioral problems such as feather pecking and cannibalism are reported as current problems on laying hen farms. However, the epidemiological prevalence of these issues in Bavaria, Germany, is not known. The objective of the present survey was to determine the epidemiological prevalence of health and behavioral parameters and the management of hen farms in practice. The survey was sent to all laying hen farmers with more than 1,000 hens in Bavaria, Germany, and contained questions regarding flock management, behavior problems and health issues...
June 23, 2017: Poultry Science
https://www.readbyqxmd.com/read/28651005/optimization-of-a-murine-and-human-tissue-model-to-recapitulate-dermal-and-pulmonary-features-of-systemic-sclerosis
#2
Tomoya Watanabe, Tetsuya Nishimoto, Logan Mlakar, Jonathan Heywood, Maya Malaab, Stanley Hoffman, Carol Feghali-Bostwick
The murine bleomycin (BLM)-induced fibrosis model is the most widely used in systemic sclerosis (SSc) studies. It has been reported that systemic delivery of BLM via continuous diffusion from subcutaneously implanted osmotic minipumps can cause fibrosis of the skin, lungs, and other internal organs. However, the mouse strain, dosage of BLM, administration period, and additional important features differ from one report to the next. In this study, by employing the pump model in C57BL/6J mice, we show a dose-dependent increase in lung fibrosis by day 28 and a transient increase in dermal thickness...
2017: PloS One
https://www.readbyqxmd.com/read/28650763/posttraumatic-retronychia-of-the-foot-with-clinical-and-ultrasound-correlation
#3
Mariana Pizarro, Nicolás Pieressa, Ximena Wortsman
Retronychia, the posterior embedding of the nail bed into the proximal nail fold, can be a complex clinical dermatologic diagnosis that may mimic other inflammatory ungual diseases or tumors of the nail. It has been related to a history of severe systemic conditions that secondarily affect the nail matrix and is commonly associated with onychomadesis. We present a case of retronychia of the foot with a purely traumatic origin, nonconcomitant with onychomadesis, that was diagnosed by color Doppler ultrasound in a long-time practitioner of martial arts who was otherwise healthy...
May 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28650732/air-hand-wipe-and-surface-wipe-sampling-for-bisphenol-a-bpa-among-workers-in-industries-that-manufacture-and-use-bpa-in-the-united-states
#4
Cynthia J Hines, Matthew V Jackson, Annette L Christianson, John C Clark, James E Arnold, Jack R Pretty, James A Deddens
For decades, bisphenol A (BPA) has been used in making polycarbonate, epoxy, and phenolic resins and certain investment casting waxes, yet published exposure data are lacking for U.S. manufacturing workers. In 2013-2014, BPA air and hand exposures were quantified for 78 workers at six U.S. companies making BPA or BPA-based products. Exposure measures included an inhalable-fraction personal air sample on each of two consecutive work days (n = 146), pre- and end-shift hand wipe samples on the second day (n = 74 each), and surface wipe samples (n = 88)...
June 26, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28650725/exposure-to-benzene-in-a-pooled-analysis-of-petroleum-industry-case-control-studies
#5
D C Glass, A R Schnatter, G Tang, T W Armstrong, L Rushton
Cases of lymphohematopoietic cancer from three petroleum industry cohorts, matched to controls from the respective cohort, were pooled into single study. Average benzene exposure was quantitatively estimated in ppm for each job based on measured data from the relevant country, adjusted for the specific time period, site and job exposure characteristics and the certainty of the exposure estimate scored. The probability of dermal exposure and of peak exposure was also assessed. Before risk was examined, an exposure estimate comparison and rationalisation exercise was performed across the studies to ensure accuracy and consistency of approach...
June 26, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28650689/time-and-dose-dependent-claudin-contribution-to-biological-functions-lessons-from-claudin-1-in-skin
#6
Reitaro Tokumasu, Atsushi Tamura, Sachiko Tsukita
There are many types of biologic compartments in the body. Tight junctions (TJs) function to create a dynamic paracellular barrier to separate these compartments and maintain homeostasis. The TJ component claudin-1 is the major transmembrane protein responsible for forming the paracellular barrier in the epidermis; other claudins in the epidermis include claudin-3, -4, -12, -23 and -25. Accumulating evidence points to a relationship between claudin-1 and skin diseases; for example, a decrease in claudin-1 is reported in human atopic dermatitis...
June 19, 2017: Tissue Barriers
https://www.readbyqxmd.com/read/28650026/the-effect-of-pegylated-hollow-gold-nanoparticles-on-stem-cell-migration-potential-application-in-tissue-regeneration
#7
Maria Del Mar Encabo-Berzosa, Maria Sancho-Albero, Alejandra Crespo, Vanesa Andreu, Victor Sebastian, Silvia Irusta, Manuel Arruebo, Pilar Martín-Duque, Jesus Santamaria
Mesenchymal stem cells (MSCs) not only can be differentiated into different cell types but also have tropism towards injured or inflamed tissues serving as repair cells. Here we have demonstrated that MSCs containing gold nanoparticles (GNPs) whose surface has been functionalized with PEG show accelerated cell migration, successful scaffold colonization and regeneration. We report the impact of GNPs on the migration (by the wound healing assay), and proliferation (by flow cytometry analysis and by the detection of metabolic mitochondrial activity) on the behaviour of different cell lines including MSCs, HeLa cells, and human dermal fibroblasts...
June 26, 2017: Nanoscale
https://www.readbyqxmd.com/read/28649889/effectiveness-of-multi-target-therapy-in-anti-melanoma-differentiation-associated-gene-5-antibody-positive-dermatomyositis-with-early-stage-interstitial-lung-disease
#8
M Suda, Y Kataoka, Y Tomishima, T Jinta, R Rokutanda, M Kishimoto, M Okada
No abstract text is available yet for this article.
June 26, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28649803/first-detection-of-porcine-circovirus-type-3-on-commercial-pig-farms-in-poland
#9
T Stadejek, A Woźniak, D Miłek, K Biernacka
Porcine circovirus type 3 (PCV3) is a novel circovirus species recently discovered in USA and China in cases of porcine dermatitis and nephropathy syndrome, reproductive failure, respiratory disease and multisystemic inflammation. This study reports on the first identification of PCV3 in Europe, in serum from pigs from Polish farms. A total of 1,050 serum samples were collected between 2014 and 2017 from sows and 3-20 weeks old pigs from 14 commercial farms representing different regions of Poland, different size and health status...
June 26, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28649748/sonographic-comparison-of-morphologic-characteristics-between-pilonidal-cysts-and-hidradenitis-suppurativa
#10
Ximena Wortsman, Ariel Castro, Claudia Morales, Carmen Franco, Andres Figueroa
OBJECTIVES: To compare the sonographic characteristics of pilonidal cysts and hidradenitis suppurativa. METHODS: A retrospective study of sonographic examinations was performed on 2 groups: 1 with pilonidal cysts and the other with hidradenitis suppurativa. The sonographic characteristics of the pilonidal cyst and hidradenitis suppurativa groups were analyzed, compared, and correlated, including an analysis of the histologic findings. For the pilonidal cyst group, the distribution, morphologic characteristics, location, shape, diameter, axis, vascularity, and scarring were also described...
June 26, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28649650/vitamin-d-ointment-for-prevention-of-radiation-dermatitis-in-breast-cancer-patients
#11
Nicola J Nasser, Shlomit Fenig, Amiram Ravid, Ariella Nouriel, Naama Ozery, Sara Gardyn, Ruth Koren, Eyal Fenig
Radiation dermatitis occurs frequently during adjuvant radiation therapy for breast cancer. Prevention of radiation dermatitis by applying various creams and ointments has a limited success, and Aqua cream which has urea as one of its active ingredients is used in many institutions as a preventive treatment. The primary goal of this study is to assess the effect of vitamin D (calcipotriol) ointment in prevention of radiodermatitis in breast cancer patients compared to Aqua cream. Twenty-three women with localized breast cancer who underwent breast-conserving surgery and opted to receive adjuvant radiotherapy to breast only were enrolled in this study...
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/28649389/cases-of-acute-mercury-poisoning-by-mercury-vapor-exposure-during-the-demolition-of-a-fluorescent-lamp-factory
#12
Sang Yoon Do, Chul Gab Lee, Jae Yoon Kim, Young Hoon Moon, Min Sung Kim, In Ho Bae, Han Soo Song
BACKGROUND: In 2015, workers dismantling a fluorescent lamp factory in Korea were affected by mercury poisoning from exposure to mercury vapor. CASE PRESENTATION: Eighteen out of the 21 workers who participated in the demolition project presented with symptoms of poisoning and, of these, 10 had persistent symptoms even at 18 months after the initial exposure to mercury vapor. Early symptoms of 18 workers included a general skin rash, pruritus, myalgia, sleep disturbance, and cough and sputum production...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28649007/polypharmacy-and-sun-exposure-implications-for-mitochondrial-dna-deletions-in-skin
#13
Julia Montelin Powers, Gillian Murphy, Nikki Ralph, Susan M O'Gorman, James E J Murphy
Most somatic cells contain many copies of mitochondrial DNA (mtDNA). Because of both the high copy number and the lack of repair mechanisms available to mtDNA, damage to it largely goes unrepaired, and can accumulate over time. Large scale deletions are a recognised type of damage sustained by mtDNA as a consequence of exposure to the ultraviolet light in sunlight. A group of patients were identified as having abnormally high levels of either a 4977 base pair deletion (mtDNA(4977)) or 3895 base pair deletion (mtDNA(3895)), in mtDNA from sun exposed skin or skin suspected to be a non-melanoma skin cancer, but not in their non-sun exposed skin biopsies...
June 17, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28648952/extracellular-vesicles-as-biomarkers-and%C3%A2-therapeutics-in-dermatology-a%C3%A2-focus%C3%A2-on-exosomes
#14
REVIEW
Jeffrey D McBride, Luis Rodriguez-Menocal, Evangelos V Badiavas
Extracellular vesicles (exosomes, microvesicles, and apoptotic bodies) are ubiquitous in human tissues, circulation, and body fluids. Of these vesicles, exosomes are of growing interest among investigators across multiple fields, including dermatology. The characteristics of exosomes, their associated cargo (nucleic acids, proteins, and lipids), and downstream functions are vastly different, depending on the cell origin. Here, we review concepts in extracellular vesicle biology, with a focus on exosomes, highlighting recent studies in the field of dermatology...
June 22, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28648937/the-correlation-of-the-standard-5-probe-fish-assay-with-melanocytic-tumors-of-uncertain-malignant-potential
#15
Aaron Muhlbauer, Shabnam Momtahen, Martin C Mihm, James Wang, Cynthia M Magro
BACKGROUND: FISH has recently emerged as a technique to better assess the malignant potential of histologically ambiguous melanocytic lesions. However, the usefulness of FISH has not been conclusively established. The purpose of this study was to further explore the diagnostic value of FISH in distinguishing the borderline melanocytic tumor (BMT) from melanoma. METHOD: 73 cases with BMT were analyzed retrospectively from a dermatopathology database between 2010-2015...
June 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/28648807/dehydration-and-starvation-yield-energetic-consequences-that-affect-survival-of-the-american-dog-tick
#16
Andrew J Rosendale, Megan E Dunlevy, Alicia M Fieler, David W Farrow, Benjamin Davies, Joshua B Benoit
Ticks are obligate hematophagous arthropods, but may have to endure extended time (1-2 years) between feedings. During these off-host periods, ticks must contend with a multitude of environmental stresses including prolonged or repeated exposure to desiccating conditions. In this study, we measured the energetic consequences of single and repeated bouts of dehydration of American dog ticks, Dermacentor variabilis, and examined the impact of energy reserves on tick survival during dehydration. Recently molted ticks exposed to a single period at 0% relative humidity (RH) for 5 d lost ∼26% of their body water and showed 1...
June 22, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28648517/-umbilical-endometriosis-mimicking-a-keloid-in-a-young-black-woman-a-case-report
#17
H-S Kourouma, E-J Ecra, A-S Allou, M Kouyaté, Y-I Kouassi, M Kaloga, K-A Kouassi, K Kassi, K Kouamé, C Ahogo, I-P Gbery, A Sangaré
BACKGROUND: Most umbilical tumors are diagnosed as benign tumors, umbilical metastases of abdominal and pelvic tumors, or Sister Marie Joseph nodule. Herein, we report a case of cutaneous umbilical endometriosis mistaken for a keloid. PATIENTS AND METHODS: A young black woman aged 26 consulted for a painful umbilical tumefaction. She had noted the appearance of a nodule of the umbilicus 10 months ago with bleeding during her menstrual periods. Skin examination revealed a firm and painful umbilical nodule 2...
June 22, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28648041/-effects-of-hypoxia-on-the-phenotype-transformation-of-human-dermal-fibroblasts-to-myofibroblasts-and-the-mechanism
#18
B Zhao, F Han, W Zhang, X J Wang, J Zhang, F F Yang, J H Shi, L L Su, D H Hu
Objective: To investigate the effects of hypoxia on the phenotype transformation of human dermal fibroblasts to myofibroblasts and the mechanism. Methods: The third passage of healthy adult human dermal fibroblasts in logarithmic phase were cultured in DMEM medium containing 10% fetal bovine serum for the following five experiments. (1) In experiments 1, 2, and 3, cells were divided into normoxia group and hypoxia group according to the random number table, with 10 dishes in each group. Cells of normoxia group were cultured in incubator containing 21% oxygen, while those of hypoxia group with 1% oxygen...
June 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28647950/turner-syndrome-care-of-the-patient-birth-to-late-adolescence
#19
Denise Gruccio Paolucci, Vaneeta Bamba
Turner syndrome (TS) is a genetic condition occurring in females resulting from the loss of part or all of one of the X chromosomes. The two hallmark features of Turner syndrome include short stature and primary ovarian insufficiency. In addition, Turner syndrome can involve multiple healthcare issues including cardiac and renal anomalies, autoimmune disorders, hearing loss, ophthalmologic issues, bone anomalies, dermatologic issues and psychosocial and educational concerns. The presenting signs of Turner syndrome can vary markedly, leading to delayed or even missed diagnosis...
June 2017: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28647616/photodynamic-therapy-in-dermatology-beyond-non-melanoma-cancer-an-update
#20
REVIEW
Xiang Wen, Yong Li, Michael R Hamblin
Photodynamic therapy (PDT) employs a photosensitizer (PS) and visible light in the presence of oxygen, leading to production of cytotoxic reactive oxygen species, which can damage the cellular organelles and cause cell death. In dermatology PDT has usually taken the form of topical application of a precursor in the heme biosynthesis pathway, called 5-aminolevulinic acid (or its methyl ester), so that an active PS, protoporphyrin IX accumulates in the skin. As PDT enhances dermal remodeling and resolves chronic inflamation, it has been used to treat cutaneous disorders include actinic keratoses, acne, viral warts, skin rejuvenation, psoriasis, localized scleroderma, some non-melanoma skin cancers and port-wine stains...
June 21, 2017: Photodiagnosis and Photodynamic Therapy
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