keyword
MENU ▼
Read by QxMD icon Read
search

Oral supplementation

keyword
https://www.readbyqxmd.com/read/29456992/national-immunization-campaigns-with-oral-polio-vaccine-reduce-all-cause-mortality-a-natural-experiment-within-seven-randomized-trials
#1
Andreas Andersen, Ane Baerent Fisker, Amabelia Rodrigues, Cesario Martins, Henrik Ravn, Najaaraq Lund, Sofie Biering-Sørensen, Christine Stabell Benn, Peter Aaby
Background: A recent WHO review concluded that live BCG and measles vaccine (MV) may have beneficial non-specific effects (NSEs) reducing mortality from non-targeted diseases. NSEs of oral polio vaccine (OPV) were not examined. If OPV vaccination campaigns reduce the mortality rate, it would suggest beneficial NSEs. Setting: Between 2002 and 2014, Guinea-Bissau had 15 general OPV campaigns and other campaigns with OPV plus vitamin A supplementation (VAS), VAS-only, MV, and H1N1 vaccine...
2018: Frontiers in Public Health
https://www.readbyqxmd.com/read/29456972/the-effect-of-levothyroxine-and-selenium-versus-levothyroxine-alone-on-reducing-the-level-of-anti-thyroid-peroxidase-antibody-in-autoimmune-hypothyroid-patients
#2
Ali Kachouei, Hassan Rezvanian, Masoud Amini, Ashraf Aminorroaya, Eshagh Moradi
Background: Due to the prevalence of autoimmune hypothyroidism and its effects on physical and mental health it is necessary to provide a treatment which is also effective in preventing the progression of sub-clinical hypothyroidism in these patients. This study aims to investigate the effect of selenium supplementation on of anti-thyroid hormone antibodies in these patients. Materials and Methods: In a randomized clinical trial, 70 patients with autoimmune hypothyroidism randomly divided into two groups of 35 each, the first group was treated with oral selenium treatment with levothyroxine (LT4) and to the second group along with LT4, placebo was also prescribed...
2018: Advanced Biomedical Research
https://www.readbyqxmd.com/read/29454686/differential-effects-of-a-single-dose-of-oral-calcium-based-on-postpartum-plasma-calcium-concentration-in-holstein-cows
#3
B M Leno, R C Neves, I M Louge, M D Curler, M J Thomas, T R Overton, J A A McArt
Our objectives were to determine (1) the effect of a single dose of an oral Ca bolus within 24 h after parturition on plasma Ca concentration, (2) the response of primiparous (PP) and multiparous (MP) cows to this supplementation strategy, and (3) differential responses based on plasma Ca at enrollment. For objective 1, cows from 1 commercial dairy in New York State were enrolled within 19 h after parturition (mean ± standard deviation = 8.3 ± 5.3 h) and randomized within parity group (first, second, and ≥third) to control [CON (n = 25); no placebo] or a single dose bolus treatment [BOL (n = 25); 3 oral Ca boluses supplying 54 to 64 g of Ca]...
February 14, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29453755/effect-of-nicotine-on-repeated-bouts-of-anaerobic-exercise-in-nicotine-na%C3%A3-ve-individuals
#4
Robert Johnston, Melissa Crowe, Kenji Doma
PURPOSE: Nicotine is a psychostimulant that is reported to be commonly supplemented by athletes. The purpose of the current study was to determine the effects of a rapidly absorbed form of nicotine on repeated bouts of anaerobic exercise, perception of exertion and a range of cardiovascular variables while monitoring side effect profiles. METHODS: Sixteen healthy, nicotine naïve male athletes (24.1 ± 5.3 years, 179.0 ± 8.8 cm, 81.7 ± 13.5 kg, BMI 25.5 ± 3.0, Body fat% 13...
February 16, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29453750/administration-of-lactobacillus-plantarum-lp62-to-dam-rats-at-the-end-of-delivery-and-during-lactation-affects-tgf-%C3%AE-1-level-and-nutritional-milk-composition-and-body-weight-of-pups
#5
Gladistone Correia Messias, Ana Marta Novais Rocha, Beatriz Manuela Silva Santos, Ana Marques Botelho, Dhaísa Cristhina Alves Silva, Erika Santos Porto, Marina Lima Dos Anjos, Rayra Almeida Sousa, Mara Viana Silva, Thainara Barros da Rocha, Aracely Vieira de Melo, Manoela Rios Trindade Carneiro, Nayonara Santana Aguiar, Patrícia Prado Santos, Erika Pereira de Souza, Mariluze Peixoto Cruz, Lucas Miranda Marques, Raquel Passos Rezende, Carla Cristina Romano, Ana Paula Uetanabaro, Gabriel Vinderola, Regiane Yatsuda
PURPOSE: Lactobacillus plantarum Lp62 is a lactic acid bacteria strain that has been isolated from cocoa beans and exhibited probiotic potential. The influence of oral administration of L. plantarum Lp62 on the growth of rat's pups; on yield, cytokines and milk composition was studied. METHODS: Lactobacillus plantarum Lp62 is a lactic acid bacteria strain that has been isolated from cocoa beans. It was administered daily by gavage to Wistar rats (n = 8), from the 7th day before delivery and for 20 days during lactation, in a concentration of 1...
February 16, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29453431/delayed-gut-microbiota-development-in-high-risk-for-asthma-infants-is-temporarily-modifiable-by-lactobacillus-supplementation
#6
Juliana Durack, Nikole E Kimes, Din L Lin, Marcus Rauch, Michelle McKean, Kathryn McCauley, Ariane R Panzer, Jordan S Mar, Michael D Cabana, Susan V Lynch
Gut microbiota dysbiosis and metabolic dysfunction in infancy precedes childhood atopy and asthma development. Here we examined gut microbiota maturation over the first year of life in infants at high risk for asthma (HR), and whether it is modifiable by early-life Lactobacillus supplementation. We performed a longitudinal comparison of stool samples collected from HR infants randomized to daily oral Lactobacillus rhamnosus GG (HRLGG) or placebo (HRP) for 6 months, and healthy (HC) infants. Meconium microbiota of HRP participants is distinct, follows a delayed developmental trajectory, and is primarily glycolytic and depleted of a range of anti-inflammatory lipids at 6 months of age...
February 16, 2018: Nature Communications
https://www.readbyqxmd.com/read/29450666/recent-advances-in-hyaluronic-acid-based-therapy-for-osteoarthritis
#7
REVIEW
Steven Bowman, Mohamed E Awad, Mark W Hamrick, Monte Hunter, Sadanand Fulzele
Osteoarthritis is a debilitating disease that has increased in prevalence across the world due to the aging population. Currently, physicians use a plethora of treatment strategies to try and slow down the progression of the disease, but none have been shown to ubiquitously treat and cure the disease. One of the strategies uses the high molecular weight molecule hyaluronic acid as either an injectable or oral supplement for treatment. Hyaluronic acid (HA) is a relatively new treatment that has shown varied results through several clinical trials...
February 16, 2018: Clinical and Translational Medicine
https://www.readbyqxmd.com/read/29450585/effect-of-isolated-vitamin-d-supplementation-on-bone-turnover-markers-in-younger-postmenopausal-women-a-randomized-double-blind-placebo-controlled-trial
#8
J Nahas-Neto, L M Cangussu, C L Orsatti, F N Bueloni-Dias, P F Poloni, E B Schmitt, E A P Nahas
Vitamin D (VD) plays an important role in bone mineralization. The present study investigates the effect of VD supplementation alone on bone turnover markers in younger postmenopausal women. It has been shown that VD supplementation in postmenopausal women with hypovitaminosis D is associated with a reduction in bone turnover markers. PURPOSE: The purpose of this study is to evaluate the effect of VD supplementation alone on bone turnover markers in younger postmenopausal women. METHODS: In this double-blind, placebo-controlled trial, 160 women were randomized into the VD group (supplementation with 1000 IU of vitamin D3/day, orally; n = 80) or placebo group (n = 80)...
February 15, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29447776/the-relative-benefits-of-claims-and-electronic-health-record-data-for-predicting-medication-adherence-trajectory
#9
Jessica M Franklin, Chandrasekar Gopalakrishnan, Alexis A Krumme, Karandeep Singh, James R Rogers, Joe Kimura, Caroline McKay, Newell E McElwee, Niteesh K Choudhry
BACKGROUND: Healthcare providers are increasingly encouraged to improve their patients' adherence to chronic disease medications. Prediction of adherence can identify patients in need of intervention, but most prediction efforts have focused on claims data, which may be unavailable to providers. Electronic health records (EHR) are readily available and may provide richer information with which to predict adherence than is currently available through claims. METHODS: In a linked database of complete Medicare Advantage claims and comprehensive EHR from a multi-specialty outpatient practice, we identified patients who filled a prescription for a statin, antihypertensive, or oral antidiabetic during 2011 to 2012...
March 2018: American Heart Journal
https://www.readbyqxmd.com/read/29447046/oral-curcumin-supplementation-improves-fine-motor-function-in-the-middle-aged-rhesus-monkey
#10
Tara L Moore, Bethany G E Bowley, Penny L Shultz, Samantha M Calderazzo, Eli J Shobin, Ajay R Uprety, Douglas L Rosene, Mark B Moss
Aged individuals experience decreased fine motor function of the hand and digits, which could result, in part, from the chronic, systemic state of inflammation that occurs with aging. Recent research for treating age-related inflammation has focused on the effects of nutraceuticals that have anti-inflammatory properties. One particular dietary polyphenol, curcumin, the principal curcuminoid of the spice turmeric, has been shown to have significant anti-inflammatory effects and there is mounting evidence that curcumin may serve to reduce systemic inflammation...
February 15, 2018: Somatosensory & Motor Research
https://www.readbyqxmd.com/read/29446938/hypoglycemic-effect-of-pyrodextrins-with-different-molecular-weights-and-digestibilities-in-diet-induced-obese-mice
#11
Yan Cao, Xiaoli Chen, Ying Sun, Jialiang Shi, Xiaojuan Xu, Yong-Cheng Shi
Pyrodextrin shares some properties of resistant starch which is metabolically beneficial, and has potential applications as a functional food. In this study, we report that oral administration of pyrodextrin (50 mg/kg/d for 7 weeks) decreased the blood glucose (from 9.18±1.47 to 7.67±0.42 mmol/L), serum HbA1c, triglycerides, adipocyte size, and body weights (from 24.4±1.2 to 22.5±1.2 g) in high-fat diet-induced obese mice. The Western blotting analysis suggested that pyrodextrins decreased the intestinal SGLT-1 and GLUT-2 expression to ~70% and ~60% of the obese control to slow down glucose transportation from gut into blood, and improved the hepatic metabolism tentatively...
February 15, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29446830/prior-ingestion-of-exogenous-ketone-monoester-attenuates-the-glycemic-response-to-an-oral-glucose-tolerance-test-in-healthy-young-individuals
#12
Etienne Myette-Côté, Helena Neudorf, Hossein Rafiei, Kieran Clarke, Jonathan Peter Little
The main objectives of this study were threefold: (1) To determine whether acute ingestion of K me ; (R)-3-hydroxybutyl (R)-3-hydroxybutyrate impacts plasma glucose levels during a standardized oral glucose tolerance test (OGTT). (2) To compare changes in insulin concentrations and estimates of insulin sensitivity after acute K me supplementation. Twenty healthy participants (n = 10 males/females) aged between 18-35 years took part in a randomized crossover study. After an overnight fast, participants consumed a K me supplement (ΔG®; 0...
February 15, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29446342/effects-of-oral-supplementation-with-spirulina-and-chlorella-on-growth-and-digestive-health-in-piglets-around-weaning
#13
H Furbeyre, J van Milgen, T Mener, M Gloaguen, E Labussière
Weaning of piglets is associated with important changes in gut structure and function resulting from stressful events such as separation from the sow, moving to a new facility and dietary transition from a liquid to a solid feed. This may result in post-weaning diarrhoea and a decrease in feed intake and growth. In humans, the cyanobacterium Spirulina platensis (SP) and the freshwater microalga Chlorella vulgaris (CV) are known for their beneficial health effects. This study aimed to determine the effects of early oral administration of Spirulina and Chlorella in piglets on mucosal architecture and cytokine expression in the intestine around weaning, and consequences on growth performance and diarrhoea incidence...
February 15, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29446222/engineering-controls-in-veterinary-oncology-a-survey-of-148-acvim-board-certified-oncologists-and-environmental-surveillance-in-20-specialty-hospitals
#14
K Alexander, N Northrup, D Clarke, H Lindell, T Laver
Engineering controls (EC, facility and equipment barriers between hazards and people) are used to avoid exposure to chemotherapy drugs. In this study, American College of Veterinary Internal Medicine board-certified veterinary oncologists were surveyed about their use of containment primary EC (C-PEC) and supplemental EC (closed system transfer devices, CSTD). The survey was completed by 148 (38%) of practicing diplomates. All used EC. Both C-PEC and CSTD were used at 92% of hospitals; however, US Pharmacopoeial Convention Chapter <800> (USP <800>) standards were met at only 19% of hospitals and oncologists did not know the type of C-PEC at 18% of hospitals...
February 15, 2018: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/29444501/quercetin-therapy-for-selected-patients-with-pim1-kinase-positive-chronic-lymphocytic-leukemia-small-lymphocytic-lymphoma-a-pilot-study
#15
Beverly W Baron, Michael J Thirman, Mihai C Giurcanu, Joseph M Baron
We reported that PIM1 kinase is expressed in the lymphocytes of patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL). Quercetin, a naturally occurring flavonoid, is a dietary supplement and inhibits many kinases, including PIM1, in vitro. Under an Institutional Review Board-approved protocol, we performed an open-label, single-arm pilot study to evaluate the antitumor activity of quercetin in patients with CLL/SLL. Q-ForceTM chews were administered orally, 500 mg twice daily, for 3 months...
February 14, 2018: Acta Haematologica
https://www.readbyqxmd.com/read/29443649/use-of-charity-financial-assistance-for-novel-oral-anticancer-agents
#16
Adam J Olszewski, Andrew R Zullo, Christopher R Nering, Justin P Huynh
Novel oral targeted drugs are increasingly used for cancer therapy, but their extreme cost, often exceeding $10,000 per month, poses a significant barrier for patients and insurers alike, leading to the potential breakdown of traditional cost-sharing strategies. Insured patients' routine use of charity assistance to supplement their coverage would indicate a major deficiency in the current health care policies. By using data from a specialty pharmacy affiliated with an academic center (1,557 prescriptions dispensed between January 2014 and March 2017), we examined sources of payment for novel oral anticancer agents, distinguishing contributions from health insurance, patients, and from charitable assistance organizations...
February 13, 2018: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29442401/single-arm-phase-ii-study-of-oral-vitamin-b12-for-the-treatment-of-musculoskeletal-symptoms-associated-with-aromatase-inhibitors-in-women-with-early-stage-breast-cancer
#17
Aleli Campbell, Rosalinda Heydarian, Cecilia Ochoa, Alok Kumar Dwivedi, Zeina A Nahleh
Breast cancer patients receiving endocrine therapy with aromatase Inhibitors (AIs) often experience musculoskeletal and joint-related side effects. The purpose of this study was to evaluate the effect of Vitamin B12 supplements on musculoskeletal symptoms such as pain and arthralgias induced by AIs and to correlate response with serum and inflammatory biomarkers. Upon receiving approval by the Institutional Review Board (IRB), the majority of the patients consented into the study were treated at the Texas Tech Breast Care Center...
February 14, 2018: Breast Journal
https://www.readbyqxmd.com/read/29442353/the-effect-of-vitamin-d-supplementation-on-sexual-functioning-and-depressive-symptoms-in-young-women-with-low-vitamin-d-status
#18
Robert Krysiak, Anna Szwajkosz, Bogdan Marek, Bogusław Okopień
BACKGROUND: Hypovitaminosis D is associated with abnormal female sexual functioning. The aim of our study was to assess whether vitamin D supplementation affects sexual functioning and depressive symptoms in young women with low vitamin D status. METHODS: The study included 47 women with vitamin D deficiency or insufficiency. All women with vitamin D deficiency were treated with oral vitamin D, while women with vitamin D insufficiency were either treated with vitamin D or left untreated...
February 14, 2018: Endokrynologia Polska
https://www.readbyqxmd.com/read/29440149/cancer-cachexia-rationale-for-the-menac-multimodal-exercise-nutrition-and-anti-inflammatory-medication-for-cachexia-trial
#19
REVIEW
Tora S Solheim, Barry J A Laird, Trude R Balstad, Asta Bye, Guro Stene, Vickie Baracos, Florian Strasser, Gareth Griffiths, Matthew Maddocks, Marie Fallon, Stein Kaasa, Kenneth Fearon
Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support alone. Cachexia has a high prevalence in cancer and a major impact on patient physical function, morbidity and mortality. Despite the consequences of cachexia, there is no licensed treatment for cachexia and no accepted standard of care. It has been argued that the multifactorial genesis of cachexia lends itself to therapeutic targeting through a multimodal treatment...
February 9, 2018: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/29439405/cholecalciferol-additively-reduces-serum-parathyroid-hormone-levels-in-severe-secondary-hyperparathyroidism-treated-with-calcitriol-and-cinacalcet-among-hemodialysis-patients
#20
Cai-Mei Zheng, Chia-Chao Wu, Chi-Feng Hung, Min-Tser Liao, Jia-Fwu Shyu, Yung-Ho Hsu, Chien-Lin Lu, Yuan-Hung Wang, Jing-Quan Zheng, Tian-Jong Chang, Yuh-Feng Lin, Kuo-Cheng Lu
We evaluated the improvement of intact parathyroid hormone (iPTH) levels and bone parameters by supplementing nutritional vitamin D (cholecalciferol) to combined calcimimetic (cinacalcet) and active vitamin D analog (calcitriol) among severe secondary hyperparathyroidism (SHPT) hemodialysis (HD) patients. A randomized, controlled open-label study was undertaken in 60 HD patients with serum iPTH > 1000 pg/mL or persistently high iPTH ≥ 600 pg/mL even after >3 months of calcitriol (3 μg/week). The study group received oral cholecalciferol (5000 IU/ day) and the control group received a placebo...
February 10, 2018: Nutrients
keyword
keyword
9092
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"