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Tethered spinal cord

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https://www.readbyqxmd.com/read/28065719/the-currarino-triad-what-pediatric-surgeons-need-to-know
#1
Amr Abdelhamid AbouZeid, Shaimaa Abdelsattar Mohammad, Mohammad Abolfotoh, Ahmed Bassiouny Radwan, Mohamed Mohamed ElSayed Ismail, Tarek Ahmed Hassan
PURPOSE: We report our experience in managing a group of patients with Currarino syndrome, highlighting diagnostic challenges, surgical techniques, in addition to a review of current neurosurgical options. PATIENTS AND METHODS: The study included patients with Currarino syndrome who presented to our pediatric surgery department during the period 2010 through 2016. The 'sacral scimitar' in plain X-ray provided the clue for the diagnosis; while MRI examination was essential to define the nature of the presacral mass and associated spinal anomalies...
December 27, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28059708/impact-of-mr-neurography-in-patients-with-chronic-cauda-equina-syndrome-presenting-as-chronic-pelvic-pain-and-dysfunction
#2
J R Petrasic, A Chhabra, K M Scott
BACKGROUND AND PURPOSE: Chronic cauda equina syndrome, defined as persistent damage of the cauda equina nerve roots within the spinal canal can be a challenging diagnosis with varied presentations. MR neurography imaging is more commonly being used to evaluate the lumbosacral spine of patients suspected of having subacute or chronic cauda equina syndrome. Our aim was to evaluate the impact of lumbosacral plexus MR neurography in the diagnostic thinking and therapeutic management of patients presenting with chronic pelvic pain and dysfunction and suspected chronic cauda equina syndrome...
November 10, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28058831/peptide-tethered-hydrogel-scaffold-promotes-recovery-from-spinal-cord-transection-via-synergism-with-mesenchymal-stem-cells
#3
Li-Ming Li, Min Han, Xin-Chi Jiang, Xian-Zhen Yin, Fu Chen, Tian-Yuan Zhang, Hao Ren, Ji-Wen Zhang, Ting-Jun Hou, Zhong Chen, Hong-Wei Ou-Yang, Yasuhiko Tabata, You-Qing Shen, Jian-Qing Gao
Spinal cord injury (SCI) is one of the most devastating injuries. Treatment strategies for SCI are required to overcome comprehensive issues. Implantation of biomaterial scaffolds and stem cells has been demonstrated to be a promising strategy. However, a comprehensive recovery effect is difficult to achieve. In the comprehensive treatment process, the specific roles of the implanted scaffolds and of stem cells in combined strategy are usually neglected. In this study, a peptide-modified scaffold is developed based on hyaluronic acid and an adhesive peptide PPFLMLLKGSTR...
February 1, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27884878/comparison-of-3-different-types-of-spinal-arteriovenous-shunts-below-the-conus-in-clinical-presentation-radiologic-findings-and-outcomes
#4
T Hong, J E Park, F Ling, K G terBrugge, M Tymianski, H Q Zhang, T Krings
BACKGROUND AND PURPOSE: Spinal arteriovenous shunts below the conus constitute 3 types of lesions, which have previously been mainly described in case reports, given their rarity, and are sometimes misdiagnosed. The purpose of this study was to describe the features of each type and compare these types as to epidemiologic features, clinical and radiologic presentations, treatment, and outcomes in a consecutive series of 48 cases. MATERIALS AND METHODS: The prospectively collected data bases of 2 referral centers for spinal vascular lesions were retrospectively reviewed...
November 24, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27861396/surgical-treatments-on-adult-tethered-cord-syndrome-a-retrospective-study
#5
Jun Gao, Xiangyi Kong, Zhimin Li, Tianyu Wang, Yongning Li
To investigate effects of surgical treatment on adult tethered cord syndrome (TCS).A retrospective analysis of 82 adult patients (17 male cases, 82% and 24 female cases, 59%) with TCS treated by surgery was conducted between March, 2005 and December, 2015, with an average age of 31.6 years and average disease course of 6.7 years. All the 82 cases of patients received nerve electrophysiology monitoring assisted microsurgery. After surgery, all patients were followed up for an average of 2.5 years. Surgical effects were evaluated according to Hoffman grading system...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27843691/co-existing-spinal-intradural-ependymal-cyst-and-sacral-tarlov-cyst-in-adult-onset-tethered-cord-syndrome-with-syringomyelia-case-report-and-literature-review
#6
Hamid H Rai, Muhammad F Khan, Syed Ather Enam, Imtiaz Hashmi
BACKGROUND: Synchronous spinal intradural ependymal cysts and sacral Tarlov cysts in adult onset tethered cord syndrome are extremely rare. CASE DESCRIPTION: A 23-year-old male presented with back pain radiating into both lower extremities, accompanied by acute onset of gait difficulty and sphincter dysfunction. Magnetic resonance imaging identified a low lying conus medullaris, syringomyelia with septations extending from T12 to S1, a tethered cord, and a thickened filum terminale with a sacral Tarlov cyst...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27833778/magnetic-resonance-imaging-analysis-of-caudal-regression-syndrome-and-concomitant-anomalies-in-pediatric-patients
#7
Deb K Boruah, Dhaval D Dhingani, Sashidhar Achar, Arjun Prakash, Antony Augustine, Shantiranjan Sanyal, Manoj Gogoi, Kangkana Mahanta
OBJECTIVE: The aim of this study was to evaluate the magnetic resonance imaging (MRI) findings of caudal regression syndrome (CRS) and concomitant anomalies in pediatric patients. MATERIALS AND METHODS: A hospital-based cross-sectional retrospective study was conducted. The study group comprised 21 pediatric patients presenting to the Departments of Radiodiagnosis and Pediatric Surgery in a tertiary care hospital from May 2011 to April 2016. All patients were initially evaluated clinically followed by MRI...
2016: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/27830790/a-brain-spine-interface-alleviating-gait-deficits-after-spinal-cord-injury-in-primates
#8
Marco Capogrosso, Tomislav Milekovic, David Borton, Fabien Wagner, Eduardo Martin Moraud, Jean-Baptiste Mignardot, Nicolas Buse, Jerome Gandar, Quentin Barraud, David Xing, Elodie Rey, Simone Duis, Yang Jianzhong, Wai Kin D Ko, Qin Li, Peter Detemple, Tim Denison, Silvestro Micera, Erwan Bezard, Jocelyne Bloch, Grégoire Courtine
Spinal cord injury disrupts the communication between the brain and the spinal circuits that orchestrate movement. To bypass the lesion, brain-computer interfaces have directly linked cortical activity to electrical stimulation of muscles, and have thus restored grasping abilities after hand paralysis. Theoretically, this strategy could also restore control over leg muscle activity for walking. However, replicating the complex sequence of individual muscle activation patterns underlying natural and adaptive locomotor movements poses formidable conceptual and technological challenges...
10, 2016: Nature
https://www.readbyqxmd.com/read/27822765/syringomyelia-caused-by-an-arachnoid-web-in-a-patient-with-shunted-dandy-walker-malformation
#9
Hee Chang Lee, Jung Won Choi, Ji Yeoun Lee, Ji Hoon Phi, Seung-Ki Kim, Byung-Kyu Cho, Kyu-Chang Wang
INTRODUCTION: Dandy-Walker malformation (DWM) is a congenital brain anomaly characterized by dysgenesis of the cerebellar vermis and the presence of a posterior fossa cyst. The association of syringomyelia with DWM is extremely rare. CASE REPORT: A 10-year-old patient who was diagnosed with DWM in infancy presented with progressive scoliosis and fecal incontinence. He had been treated with cystoventriculoperitoneal shunting with a Y-connection during infancy, which was followed by a revision 6 years later...
November 7, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27794580/think-of-the-conus-medullaris-at-the-time-of-diagnosis-of-fetal-sacral-agenesis
#10
Nicolas Mottet, Jelena Martinovic, Claire Baeza, Fabien Guimiot, Jean-Philippe Bault, Marie Cécile Aubry, Didier Riethmuller, Michel Zerah, Celia Cretolle, Alexandra Benachi
BACKGROUND: There is no precise prenatal indicator to refine an accurate prognosis in case of sacral agenesis and to define the diagnostic approach and outcome criteria in case of fetal sacral agenesis using 3 characteristics of the conus medullaris (CM): its position, its appearance, and associated spinal abnormalities. METHODS: Ten cases of prenatally diagnosed sacral agenesis were included between 1995 and 2014 after collating ultrasound findings and prenatal computed tomography data...
October 29, 2016: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/27790529/successful-pregnancy-outcome-in-an-operated-case-of-lipomeningomyocele-a-rare-case
#11
Vineet Vashistha Mishra, Sakshi Nanda, Rohina Aggarwal, Tanvir
Lipomeningomyocele is one of the types of occult spinal dysraphism associated with tethered cord syndrome, which is characterised by neurodeficit symptomatology due to stretch- induced functional disorder of the spinal cord with its caudal part attached by an in elastic tissue. There is stretching of conus medullaris and nerve roots due to disproportionate growth between vertebral column and spinal cord, resulting in various neurological deficits. Its incidence is approximately 1 in 4000 births in the USA, with a slightly higher female preponderance, although its true incidence is not known...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27727200/combined-strength-exercises-in-dry-land-and-in-the-water-to-improve-swimming-parameters-of-athletes-with-paraplegia
#12
Kestutis Skucas, Vaida Pokvytyte
BACKGROUND: Of the research was to examine the effects of twelve weeks of combined dry land strength and resistance swimming training for increasing upper body strength, swimming performance and stroking parameters in swimmers with paraplegia and to determine correlation between these parameters. METHODS: The preliminary, the second (after 4 weeks), the third (after 8 weeks) and the last (after 12 weeks) testing were performed. The measurements consisted of the following assessments: the assessment of isometric strength in dry land (tension force), the assessment of swimming performance and stroke parameters during 50m backstroke, the assessment of strength during tethered swimming (tension force)...
October 11, 2016: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/27725298/scarcity-of-implants-has-partially-replaced-cervical-spondylotic-myelopathy-decompression-and-instrumented-fusion-with-implant-less-expansile-cervical-laminoplasty-poverty-teaches-all-the-arts
#13
Marin Stančić, Ivana Stančić, Petra Barl, Ivan Pašalić
OBJECTIVE: The scarcity of implants during the economic crisis partially has replaced decompression and instrumented fusion for the treatment of cervical spondylotic myelopathy with implant-less expansile cervical laminoplasty (ECL). The aim of the study was to compare the results obtained with instrumented anterior cervical corpectomy and fusion with implant-less ECL. METHODS: Patients suffering from cervical spondylotic myelopathy Nurick 3-5 with preoperative tethering and postoperative untethering were included...
January 2017: World Neurosurgery
https://www.readbyqxmd.com/read/27673095/poster-342-tethered-cord-syndrome-in-a-patient-with-40-year-history-of-spinal-cord-injury-a-case-report
#14
Arlene Lazaro, Miguel X Escalon, Mariam Zakhary
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27651783/association-between-chromosomal-aberration-of-cox8c-and-tethered-spinal-cord-syndrome-array-based-comparative-genomic-hybridization-analysis
#15
Qiu-Jiong Zhao, Shao-Cong Bai, Cheng Cheng, Ben-Zhang Tao, Le-Kai Wang, Shuang Liang, Ling Yin, Xing-Yi Hang, Ai-Jia Shang
Copy number variations have been found in patients with neural tube abnormalities. In this study, we performed genome-wide screening using high-resolution array-based comparative genomic hybridization in three children with tethered spinal cord syndrome and two healthy parents. Of eight copy number variations, four were non-polymorphic. These non-polymorphic copy number variations were associated with Angelman and Prader-Willi syndromes, and microcephaly. Gene function enrichment analysis revealed that COX8C, a gene associated with metabolic disorders of the nervous system, was located in the copy number variation region of Patient 1...
August 2016: Neural Regeneration Research
https://www.readbyqxmd.com/read/27635168/case-report-pseudotail-with-dermal-sinus-tract-and-tethered-cord
#16
Paul Clark, Laurence Davidson
A pseudotail is a very rare, dermal appendage arising from the lumbosacral region with an association with spinal dysraphism. We report a case of a pseudotail in a healthy newborn female with sonographic imaging of a tethered cord and dermal sinus tract with MRI and surgical correlation.
September 2016: Journal of Ultrasound
https://www.readbyqxmd.com/read/27606029/a-tale-of-two-tails-a-curiosity-revisited
#17
Nishanth Sadashiva, Manish Beniwal, Dhaval Shukla, Dwarakanath Srinivas
A human tail or a caudal appendage is a rare condition with preconceived notions and stigmata. They could be either true tails or "pseudotails" based on their embryology. Clinically, they are considered as a marker of occult spinal dysraphism. We report two such cases with tethering of cord, one of which was associated with a lipomeningomyelocele. These patients are in need of meticulous evaluation and appropriate management.
April 2016: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/27593844/are-herniated-cerebellar-tonsils-the-main-culprit-of-chiari-malformation-type-i-symptoms-brainstem-compression-hypothesis-seems-to-be-re-elucidated-and-revised
#18
Mehmet Selcuki, Mesut Mete, Deniz Selcuki
AIM: The Chiari Malformation I (CM I) and tethered cord syndrome (TCS) are both congenital abnormalities whose mechanism are still not fully understood. Associaton of CM I and TCS have been reported only for a few times previously Material and Methods: This retrospective study includes 7 patients who were diagnosed with CM I and TCS managed by cutting of the filum terminale. RESULTS: The mean follow-up period was 21 months and 28 days. Although all patients were undergone untethering surgical procedure by cutting the filum terminale only, all patients reported significant early postsurgical resolution of CM I symptoms and symptoms related to TCS as well...
July 1, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27593807/comparison-of-electrophysiological-outcomes-of-tethered-cord-syndrome-and-spinal-intradural-tumors-a-retrospective-clinical-study
#19
Serhat Pusat, Cahit Kural, Ilker Solmaz, Caglar Temiz, Yunus Kacar, Ozkan Tehli, Murat Kutlay, Mehmet Daneyemez, Yusuf Izci
AIM: Electrophysiological evaluation of the outcomes of spinal procedures is important for neurosurgeons. Somotosensorial evoqued potentials (SSEPs) are used for electrophysiological evaluation of tethered cord syndrome (TCS) and spinal intradural tumors (SIT). The aim of this study is to document the electrophysiological outcomes of surgery for TCS and SIT and to compare the results based on the preoperative diagnosis. MATERIAL AND METHODS: The data of 30 patients, who were operated for TCS and SIT between 2011 and 2013, were reviewed retrospectively...
February 5, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27559452/variation-in-outcome-in-tethered-cord-syndrome
#20
Noorulain Iqbal, Mohsin Qadeer, Salman Yousuf Sharif
STUDY DESIGN: Fifty patients surgically treated for tethered cord syndrome (TCS) were retrospectively studied at Liaquat National Hospital, Karachi from 2010 until 2014. PURPOSE: To assess the common presentations of TCS in our part of the world and the surgical outcome of the different presentations. OVERVIEW OF LITERATURE: TCS is a stretch-induced functional disorder of the spinal cord with its caudal part anchored by an inelastic structure, which results in characteristic symptoms and signs...
August 2016: Asian Spine Journal
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