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Epithelioid angiosarcoma

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https://www.readbyqxmd.com/read/29136688/-characteristics-of-erg-fli-1-cd34-cd31-and-f%C3%A2-rag-expression-in-hepatic-malignant-vascular-tumors
#1
Z B Wang, X J An, J F Deng, J H Liu, H Y Shi
Objective: To investigate the expression of ERG, Fli-1, CD34, CD31 and factor Ⅷ-related antigen(FⅧRAg) in hepatic malignant vascular tumors. Methods: A retrospective analysis was conducted on 63 cases of primary hepatic malignant vascular tumors and 31 cases of hepatic other malignant spindle cell tumors collected during January 1986 to January 2014. EnVision method was used to detect the expression of ERG, Fli-1, CD34, CD31, FⅧRAg. Results: Sixty-three cases of malignant vascular tumors, including 24 cases of angiosarcoma, 38 cases of epithelioid hemangioendothelioma and 1 case of hepatic Kaposi's sarcoma...
November 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29104110/pseudomyogenic-hemangioendothelioma-of-skin-bone-and-soft-tissue-a-clinicopathological-immunohistochemical-and-fluorescence-in-situ-hybridization-study
#2
Dinesh Pradhan, Karen Schoedel, Richard L McGough, Sarangarajan Ranganathan, Uma N M Rao
Pseudomyogenic hemangioendothelioma (PHE) is an uncommon neoplasm with propensity for local recurrence. The tumor mimics epithelioid hemangioendothelioma and epithelioid sarcoma, representing a possible diagnostic pitfall. We investigated the clinicopathological, immunohistochemical and fluorescence in situ hybridization features of PHEs. Eight cases of PHE were retrieved from our pathology archives. The clinical and outcome information was available in six patients. In six cases the tumors were located in the lower limb while the upper limb was involved in two cases...
November 2, 2017: Human Pathology
https://www.readbyqxmd.com/read/29102969/hepatic-epithelioid-haemangioendothelioma-hehe-a-diagnostic-dilemma-between-haemangioma-and-angiosarcoma
#3
Belle Vivica van Rosmalen, Joanne Verheij, Saffire S K S Phoa, Thomas Matthijs van Gulik
We present a case of a 77-year-old male patient with a liver tumour diagnosed as hepatic epithelioid haemangioendothelioma (HEHE), a potentially malignant tumour treated with liver resection. The patient is disease-free 3 years after resection. Imaging features using fludeoxyglucose F 18 positron emission tomography CT and MRI with gadoxic acid as well as histopathological findings are discussed.
November 3, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29079914/mri-features-of-primary-rare-malignancies-of-the-liver-a-report-from-four-university-centres
#4
Richard C Semelka, Nadesan Nimojan, Saman Chandana, Miguel Ramalho, Suzanne L Palmer, Danielle DeMulder, Carolina Parada Villavicencio, John Woosley, Bonnie L Garon, Reena C Jha, Frank H Miller, Ersan Altun
PURPOSE: To determine if rare primary malignancies of the liver may have consistent features on magnetic resonance imaging (MRI). MATERIALS AND METHODS: This IRB-compliant retrospective study reviewed the records from the pathology departments of four university centres over an 11-year period from 2005-2016 to identify rare primary malignant tumours, which were cross-referenced with MRI records. MRI studies of these patients were reviewed to determine if these tumours exhibited consistent and distinctive features...
October 27, 2017: European Radiology
https://www.readbyqxmd.com/read/29030282/epithelioid-hemangioendothelioma-an-uncommon-tumor-of-the-eyelid-a-case-report
#5
M A Ennouhi, A Guerrouani, A Moussaoui
Epithelioid hemangioendothelioma (EHE) is an infrequent vascular tumor that has an intermediate prognosis between the prognosis of the angioma and that of the angiosarcoma. Its evolution is characterized by a tendency to recurrence and metastases. EHE has been reported in locations such as: lungs, liver, bone and soft tissues. There are very few reports of cases involving the head and neck region. The occurrence of EHE in the orbital region and/or the eyelid is extremely rare. The authors report a case of EHE in the right upper eyelid...
October 11, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29021485/spontaneous-regression-of-epithelioid-angiosarcoma-in-a-young-woman
#6
Suya Hori, Motoko Tachihara, Daisuke Tamura, Kazuyuki Kobayashi, Kyosuke Nakata, Hiroshi Kamiryo, Yasuhiro Sakai, Tomoo Itoh, Takanori Hirose, Yoshihiro Nishimura
A 20-year-old Japanese woman with a history of pulmonary atresia was referred to our hospital after the detection of an abnormal mass in the right lung and mediastinal lymphadenopathy. A cytological specimen obtained by transbronchial brushing indicated that the pathological diagnosis was non-small cell lung cancer. During the follow-up period, the tumor spontaneously regressed. At four months after the diagnosis, she experienced sudden bleeding from the small intestine. The histological characteristics of the small intestine tumor were compatible with the cytological characteristics of the lung tumor...
October 11, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28989828/magnetic-resonance-imaging-of-primary-hepatic-malignancies-in-patients-with-and-without-chronic-liver-disease-a-pictorial-review
#7
REVIEW
Lauren F Alexander, Peter Harri, Brent Little, Courtney C Moreno, Pardeep K Mittal
Primary hepatic malignancies are less common than metastatic diseases, but a recognition of these lesions is important for diagnosis and treatment planning. Magnetic resonance imaging (MRI) provides the most imaging information to diagnose lesions noninvasively and to narrow differential diagnoses. This paper reviews the imaging findings of chronic liver disease and primary hepatic malignancies, including hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (CCA), epithelioid hemangioendothelioma, hepatic angiosarcoma, and primary hepatic lymphoma...
August 4, 2017: Curēus
https://www.readbyqxmd.com/read/28916596/cutaneous-angiosarcoma-a-current-update
#8
REVIEW
Elina Shustef, Viktoryia Kazlouskaya, Victor G Prieto, Doina Ivan, Phyu P Aung
Cutaneous angiosarcoma (cAS) is a rare malignant neoplasm with variable clinical presentation. Although a distinct vascular tumour, cAS shares many overlapping histopathological features with other vasoformative and epithelioid tumours or 'mimickers'. cAS shows aggressive behaviour and carries a grave prognosis, thus early diagnosis is of paramount importance to achieve the best possible outcomes. Recently, several genetic studies were conducted leading to the identification of novel molecular targets in the treatment of cAS...
November 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28900554/primary-epithelioid-angiosarcoma-of-lung-radiologic-and-clinicopathologic-correlation
#9
Fung Him Ng, San Ming Yu, Ophelia Ka Heng Wai, James Chi Sang Chan
Primary pulmonary angiosarcoma is extremely rare. It is often characterized by a clinically indolent course and delayed diagnosis. To date, there have been <20 cases reported. By far, little article correlates the clinical presentation, the imaging findings with the pathology. The authors present a case of middle-aged gentleman with primary pulmonary epithelioid angiosacroma which we initially thought as tuberculosis (TB) infection. A 60-year-old gentleman, with a history of 6 months on and off blood stained sputum, was admitted for an episode of massive hemoptysis...
2017: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/28879422/differentiating-primary-hepatic-angiosarcomas-from-hemangiomatosis-and-epithelioid-hemangioendotheliomas-using-gadoxetic-acid-enhanced-and-diffusion-weighted-mr-imaging
#10
Jung Wook Seo, Seong Hyun Kim, Ah Yeong Kim, Woo Kyoung Jeong, Ji Young Woo, Won Jeong Park
OBJECTIVES: To assess the value of gadoxetic acid-enhanced and diffusion-weighted (DW) magnetic resonance (MR) imaging for differentiating primary hepatic angiosarcomas from hemangiomatosis and epithelioid hemangioendotheliomas (EHEs). METHODS: We reviewed MR images of seven patients with pathologically determined hepatic angiosarcomas, 11 patients with hemangiomatosis, and five patients with EHEs. Two radiologists assessed morphologic features, signal intensity (SI), enhancement patterns, and the presence of diffusion restriction by consensus and compared between angiosarcoma vs hemangiomatosis and angiosarcoma vs EHEs...
November 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28832074/programmed-death-ligand-1-pd-l1-expression-in-malignant-mesenchymal-tumors
#11
Kemal Kösemehmetoğlu, Ece Özoğul, Berrin Babaoğlu, Gaye Güler Tezel, Gökhan Gedikoğlu
OBJECTIVE: Programmed death ligand 1 (PD-L1) found on tumor cells has recently been reported to have a key role in the development and dissemination of many tumors, such as lung and breast carcinomas. In this study, we retrospectively analyzed PD-L1 expression among different types of sarcomas. MATERIAL AND METHOD: Tissue microarrays of 3-4 mm diameter were composed from paraffin blocks of 222 various sarcomas. Slides prepared from microarrays were stained for PD-L1 antibody (Cell Signaling, E1L3N®) using Leica Bond Autostainer...
2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28810922/pleural-epithelioid-angiosarcoma-with-lymphatic-differentiation-arisen-after-radiometabolic-therapy-for-thyroid-carcinoma-immunohistochemical-findings-and-review-of-the-literature
#12
REVIEW
Daniela Cabibi, Giulia Pipitone, Rossana Porcasi, Sabrina Ingrao, Ignazio Benza, Calogero Porrello, Massimo Cajozzo, Antonino Giulio Giannone
BACKGROUND: Pleural angiosarcoma is a rare tumor that causes diffuse pleural thickening and effusion, mimicking mesothelioma. Immunohistochemistry is needed to highlight endothelial differentiation. We describe the first case of pleural angiosarcoma with lymphatic differentiation following radiometabolic therapy for thyroid carcinoma. CASE PRESENTATION: A 50-year-old man showed diffuse pleural thickening and effusion. Nine years earlier, he underwent thyroidectomy and radiometabolic therapy for thyroid carcinoma with lymph node metastases...
August 15, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/28806239/18f-fdg-pet-ct-of-secondary-epithelioid-angiosarcoma-of-the-proximal-femur-in-a-patient-with-polyostotic-fibrous-dysplasia
#13
Michiyuki Hakozaki, Hitoshi Yamada, Osamu Hasegawa, Kazuo Watanabe, Shinichi Konno
Fibrous dysplasia rarely transforms into a secondary malignancy. We present the PET/CT findings at pretreatment and posttreatment in an exceedingly rare case of epithelioid angiosarcoma of the bone secondary to polyostotic fibrous dysplasia.
October 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28802504/cutaneous-malignant-vascular-neoplasms
#14
REVIEW
Wonwoo Shon, Steven D Billings
Accurate diagnosis of cutaneous malignant vascular tumors, including angiosarcoma and epithelioid hemangioendothelioma, is critical for determination of appropriate clinical management and prognosis. Although there have been significant advances in understanding genetic aspects of cutaneous vascular biology, differential diagnosis of malignant vascular tumor involving skin and superficial soft tissue is a frequent source of difficulty. This brief overview highlights the clinicopathologic features of primary and secondary cutaneous angiosarcoma and epithelioid hemangioendothelioma and also provides a short summary of newer molecular data...
September 2017: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/28795130/epithelioid-angiosarcoma-of-the-vulva-a-case-report
#15
S Yost, J Bradish, L Grossheim, A Hoekstra
•Vulvar angiosarcoma in a patient with pelvic radiation and chronic lymphedema•Epithelioid histologic staining positive for vimentin, ERG, CD31•Gross appearance of violaceous hyperpigmentation of the mons pubis.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28766950/imaging-features-of-rare-mesenychmal-liver-tumours-beyond-haemangiomas
#16
REVIEW
Rajesh Thampy, Khaled M Elsayes, Christine O Menias, Perry J Pickhardt, Hyunseon C Kang, Sandeep P Deshmukh, Kareem Ahmed, Brinda Rao Korivi
Tumours arising from mesenchymal tissue components such as vascular, fibrous and adipose tissue can manifest in the liver. Although histopathology is often necessary for definitive diagnosis, many of these lesions exhibit characteristic imaging features. The radiologist plays an important role in suggesting the diagnosis, which can direct appropriate immunohistochemical staining at histology. The aim of this review is to present clinical and imaging findings of a spectrum of mesenchymal liver tumours such as haemangioma, epithelioid haemangioendothelioma, lipoma, PEComa, angiosarcoma, inflammatory myofibroblastic tumour, solitary fibrous tumour, leiomyoma, leiomyosarcoma, Kaposi sarcoma, mesenchymal hamartoma, undifferentiated embryonal sarcoma, rhabdomyosarcoma and hepatic metastases...
November 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28741174/angiosarcoma-around-total-hip-arthroplasty-case-series-and-review-of-the-literature
#17
REVIEW
S Terrando, A Sambri, G Bianchi, L Cevolani, L Foschi, E Gozzi, G Pignatti, D M Donati
BACKGROUND: Angiosarcoma (AS) is a rare and malignant tumor which mainly arises in the skin and superficial soft tissue and less frequently in deep soft tissue and bones. Some cases of AS are described in association with vascular and orthopedic devices. Nonetheless, only a few cases of AS around THA are reported in the literature. MATERIALS AND METHODS: We describe five cases of AS arising around total hip arthroplasty who received surgery at our institution (Istituto Ortopedico Rizzoli, Bologna, Italy), and we report the cases described in literature...
July 24, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28731049/composite-hemangioendothelioma-with-neuroendocrine-marker-expression-an-aggressive-variant
#18
Kyle D Perry, Alyaa Al-Lbraheemi, Brian P Rubin, Jin Jen, Hongzheng Ren, Jin Sung Jang, Asha Nair, Jaime Davila, Stefan Pambuccian, Andrew Horvai, William Sukov, Henry D Tazelaar, Andrew L Folpe
Aberrant expression of neuroendocrine markers is extremely rare in endothelial neoplasms, with only a single report describing three cases. Although originally classified as conventional angiosarcoma, further assessment of these tumors revealed a strikingly composite morphology composed of retiform and epithelioid elements reminiscent of composite hemangioendothelioma, a rare subtype of hemangioendothelioma. To further investigate these findings, available materials from 11 morphologically distinctive endothelial tumors showing neuroendocrine marker expression were retrieved from our archives...
November 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28721475/epithelioid-hemangioma-of-bone-radiologic-and-magnetic-resonance-imaging-characteristics-with-histopathological-correlation
#19
Kathleen Schenker, Steven Blumer, Diego Jaramillo, Amanda L Treece, Aashim Bhatia
BACKGROUND: Epithelioid hemangioma is a rare vascular tumor that can occur in soft tissues or bone. The tumor is part of a spectrum of vascular tumors that also includes epithelioid hemangioendothelioma and angiosarcoma. When involving the bone, the tumor usually involves the metaphysis or diaphysis of the long tubular bones and most commonly occurs in adults. It has been rarely reported in pediatric patients, and in these reported patients, the tumor primarily involves the epiphysis...
November 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28702406/epithelioid-angiosarcoma-10-years-postrenal-transplant
#20
Nitin Gupta, Natasha Singh, Ameya D Puranik, Akshay Bedmutha
No abstract text is available yet for this article.
April 2017: South Asian Journal of Cancer
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