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Epithelioid angiosarcoma

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https://www.readbyqxmd.com/read/28741174/angiosarcoma-around-total-hip-arthroplasty-case-series-and-review-of-the-literature
#1
REVIEW
S Terrando, A Sambri, G Bianchi, L Cevolani, L Foschi, E Gozzi, G Pignatti, D M Donati
BACKGROUND: Angiosarcoma (AS) is a rare and malignant tumor which mainly arises in the skin and superficial soft tissue and less frequently in deep soft tissue and bones. Some cases of AS are described in association with vascular and orthopedic devices. Nonetheless, only a few cases of AS around THA are reported in the literature. MATERIALS AND METHODS: We describe five cases of AS arising around total hip arthroplasty who received surgery at our institution (Istituto Ortopedico Rizzoli, Bologna, Italy), and we report the cases described in literature...
July 24, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28731049/composite-hemangioendothelioma-with-neuroendocrine-marker-expression-an-aggressive-variant
#2
Kyle D Perry, Alyaa Al-Lbraheemi, Brian P Rubin, Jin Jen, Hongzheng Ren, Jin Sung Jang, Asha Nair, Jaime Davila, Stefan Pambuccian, Andrew Horvai, William Sukov, Henry D Tazelaar, Andrew L Folpe
Aberrant expression of neuroendocrine markers is extremely rare in endothelial neoplasms, with only a single report describing three cases. Although originally classified as conventional angiosarcoma, further assessment of these tumors revealed a strikingly composite morphology composed of retiform and epithelioid elements reminiscent of composite hemangioendothelioma, a rare subtype of hemangioendothelioma. To further investigate these findings, available materials from 11 morphologically distinctive endothelial tumors showing neuroendocrine marker expression were retrieved from our archives...
July 21, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28721475/epithelioid-hemangioma-of-bone-radiologic-and-magnetic-resonance-imaging-characteristics-with-histopathological-correlation
#3
Kathleen Schenker, Steven Blumer, Diego Jaramillo, Amanda L Treece, Aashim Bhatia
BACKGROUND: Epithelioid hemangioma is a rare vascular tumor that can occur in soft tissues or bone. The tumor is part of a spectrum of vascular tumors that also includes epithelioid hemangioendothelioma and angiosarcoma. When involving the bone, the tumor usually involves the metaphysis or diaphysis of the long tubular bones and most commonly occurs in adults. It has been rarely reported in pediatric patients, and in these reported patients, the tumor primarily involves the epiphysis...
July 18, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28702406/epithelioid-angiosarcoma-10-years-postrenal-transplant
#4
Nitin Gupta, Natasha Singh, Ameya D Puranik, Akshay Bedmutha
No abstract text is available yet for this article.
April 2017: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/28699109/malignant-mesenchymal-neoplasms-of-the-dermis-and-subcutis-mimicking-benign-lesions-a-case-based-review
#5
Thomas Mentzel, Thomas Brenn
In this short review, malignant mesenchymal neoplasms of the dermis and subcutis mimicking benign lesions and their differential diagnoses are discussed. These include plaque-like dermatofibrosarcoma protuberans, superficial low-grade fibromyxoid sarcoma, low-grade superficial malignant peripheral nerve sheath tumour, epithelioid sarcoma, pseudomyogenic haemangioendothelioma, Kaposi sarcoma mimicking cavernous haemangioma and benign lymphangioendothelioma, and rare forms of angiosarcoma mimicking a benign vascular lesion...
July 12, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28693219/f-18-fluorodeoxyglucose-positron-emission-tomography-for-differential-diagnosis-and-prognosis-prediction-of-vascular-tumors
#6
Won Woo Lee, Young So, Seo Young Kang, Min-Kyung So, Haeryoung Kim, Hyun Woo Chung, Wan Seop Kim, Sang Eun Kim
The spectrum of vascular tumors ranges from hemangioma (HEM), to epithelioid hemangioendothelioma (EHE) and to angiosarcoma (AS). To the best of our knowledge, the usefulness of F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) for vascular tumors has never been comprehensively studied. The present study investigated the usefulness of FDG-PET for pathologically diagnosed vascular tumors. The present study included 26 patients with vascular tumor (male:female, 17:9; age, 60.9±14.4 years; 7 HEM, 6 EHE and 13 AS) who underwent FDG-PET between January 2007 and May 2014 at the Seoul National University Bundang Hospital (Seongnam, Korea) and Konkuk University Medical Center, (Seoul, Korea)...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28682861/right-femoral-pathological-fracture-caused-by-primary-bone-epithelioid-angiosarcoma-case-report
#7
Yatong Li, Xiongfei Zou, Xiaoyan Chang, Xiao Chang, Shengfang Sun, Baozhong Zhang
RATIONALE: Epithelioid angiosarcoma (EAS) is an extremely rare malignant disease, which accounts no more than 1% of all soft tissue sarcomas. In this article, we would report a new case of EAS with multiple bone destruction and right femoral pathological fracture, which was an even rarer manifestation of EAS. PATIENT CONCERNS: In this case, a 64-year-old man with right femoral fracture was reported. He had suffered from a progressive low back pain for about 8 months, and the imaging examinations prompted a multiple bone destruction in his vertebra and lower limbs...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28585251/tfe3-rearranged-hepatic-epithelioid-hemangioendothelioma-a-case-report-with-immunohistochemical-and-molecular-study
#8
Fang-Ying Kuo, Hsuan-Ying Huang, Chao-Long Chen, Hock-Liew Eng, Chao-Cheng Huang
A recurrent YAP1-TFE3 gene fusion has been identified in WWTR1-CAMTA1-negative epithelioid hemangioendotheliomas arising in soft tissue, bone, and lung, but not in liver. We present the first case of TFE3-rearranged hepatic epithelioid hemangioendothelioma in a 39-year-old Taiwanese woman. Computed tomography scan revealed multifocal, ill-defined nodules involving both hepatic lobes. She then underwent deceased donor liver transplantation. Histologically, the tumors in the liver explant showed a biphasic growth pattern...
June 6, 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28552538/the-utility-of-glut1-as-a-diagnostic-marker-in-cutaneous-vascular-anomalies-a-review-of-literature-and-recommendations-for-daily-practice
#9
REVIEW
Lieke J van Vugt, Carine J M van der Vleuten, Uta Flucke, Willeke A M Blokx
OBJECTIVE: To assess the utility of GLUT1 as an immunohistochemical marker in the diagnostics of cutaneous vascular anomalies. METHODS: A systematic literature search was conducted for studies on GLUT1 staining patterns in cutaneous vascular lesions. Data was grouped according to the latest ISSVA classification for vascular anomalies. RESULTS: Vascular tumors: GLUT1 staining was positive in 368/386 (95%) of infantile hemangiomas. Congenital hemangiomas (16 cases) and kaposiform hemangioendotheliomas (62 cases) were all negative for GLUT1...
June 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28551383/a-exceptional-collision-tumor-of-primary-adrenal-angiosarcoma-and-non-functioning-adrenocortical-adenoma
#10
Katsumi Takizawa, Kenichi Kohashi, Takahito Negishi, Kenichi Taguchi, Yuichi Yamada, Motonobu Nakamura, Yoshinao Oda
Primary adrenal angiosarcoma is an extremely rare vascular tumor. We report a case of a 63-year-old man with a collision tumor of epithelioid angiosarcoma and adrenocortical adenoma of the right adrenal gland. The adrenal tumor was incidentally observed by a preoperative computed tomography (CT) scan of penis squamous cell carcinoma. The patient underwent a right laparoscopic adrenalectomy, and the tumor size measured 34×34×15mm. Histological examination revealed two different tumor cell proliferations, namely epithelioid angiosarcoma and adrenocortical adenoma...
June 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28540360/epithelioid-angiosarcoma-arising-in-a-uterine-leiomyoma-with-associated-elevated-ca-125-a-case-report
#11
Sarah V Strickland, Mark R Kilgore, Elise J Simons, Mara H Rendi
We describe the case of a 67 year old female with longstanding uterine leiomyomas who presented with fatigue, weight loss, elevated CA-125 and an enlarging mass arising from the posterior uterine fundus. Histologic sections of the mass contained a leiomyoma with interspersed foci of malignant epithelioid cells forming anastomosing vascular channels. The neoplastic cells were diffusely positive for CD31 and FLI1, supporting the morphologic impression of epithelioid angiosarcoma. Few cases of epithelioid angiosarcoma arising within a leiomyoma have been described...
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28506772/treatment-of-epithelioid-angiosarcoma-with-topical-ala-pdt-in-the-course-of-surgery
#12
Yang Gao, Wen-Sheng Wang, Hai-Lin Wang, Jia Liu, Yuan-Gang Lu
BACKGROUND: Epithelioid angiosarcoma is a kind of high grade malignancy sarcoma of soft tissue, which is hard to diagnose and completely exsect without causing functional and cosmetic problems. Moreover, the high rate of recurrence is hard to handle. Photodynamic therapy is a novel treatment protocol which can selectively destroy tumor cell with good functional and cosmetic outcomes. METHODS: This is a case about a 81 years old patient with Epithelioid angiosarcoma in the right medial angle of eye, which received surgery and photodynamic therapy...
May 12, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28480169/angiosarcoma-of-the-bladder-review-of-the-literature-and-discussion-about-a-clinical-case
#13
Florian Gerbaud, Alexandre Ingels, Sophie Ferlicot, Jacques Irani
Our reported case is a 72 year-old man who presented with hematuria. A transurethral resection of the bladder tumor (TURB-T) has been performed. Histopathological diagnosis was an epithelioid angiosarcoma. CT scan revealed a bladder thickening. The treatment consisted in a complete pelvectomy with urinary and digestive diversion. Following the operation, the patient developed liver and pulmonary metastasis. He died 5 months after the initial diagnosis.
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28478891/-epithelioid-hemangioendothelioma-of-the-spine-a-case-report
#14
O Munier, B Muckensturm, M Fesneau, T Wachter
Epithelioid hemangioendothelioma is a rare vascular tumour, with features between hemangiomas and angiosarcomas. Evolution remains mainly local but may also metastasize. Here, we report a case of a patient with a spinal epithelioid hemangioendothelioma. After a first resection, local recurrence required a new excision and external radiotherapy. It was achieved by helical TomoTherapy(®) with intensity modulation. During the follow-up, a second inoperable spinal location necessitated a new sequence of radiotherapy in modulation of intensity with integrated boost...
May 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28475514/recurrent-cutaneous-angiosarcoma-of-the-scalp-with-aberrant-expression-of-s100-a-case-report
#15
Laura Macías-García, Concepción Lara-Bohorquez, Enrique Jorquera-Barquero, Juan J Ríos-Martín
Angiosarcoma (AS) is a malignant mesenchymal neoplasm of endothelial origin with a predominantly lymphatic immunophenotype, which accounts for less than 1% of all sarcomas. Cutaneous AS of the scalp is associated with high rates of local recurrence and a poor prognosis. Histologically, poorly differentiated AS often comprises solid epithelioid cells, although rare variants involving spindle cells have been reported; diagnosis requires immunohistochemical analysis using vascular cell markers. We report on a cutaneous spindle-cell AS of the scalp in a female patient; key features included spontaneous regression after biopsy, local recurrence 2 years later, and aberrant nuclear staining for S100 protein in an area of the tumor not expressing CD34 or D2-40...
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28454305/microrna-profile-of-hepatic-epithelioid-hemangioendothelioma-a-case-report
#16
Asahiro Morishita, Hisakazu Iwama, Hirohito Yoneyama, Teppei Sakamoto, Koji Fujita, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Shintaro Fujihara, Noriko Nishiyama, Hideki Kobara, Hirohito Mori, Naoki Yamamoto, Keiichi Okano, Yasuyuki Suzuki, Emi Ibuki, Reiji Haba, Takashi Himoto, Tsutomu Masaki
A 72-year-old female was referred for further evaluation of epigastralgia. Abdominal contrast computed tomography revealed numerous tumors in the two lobes of the liver. Liver biopsy and immunohistochemical staining revealed that the tumor cells were positive for factor VIII-associated antigen, platelet endothelial cell adhesion molecule 1 and human hematopoietic progenitor cell antigen, concordant with a diagnosis of hepatic epithelioid hemangioendothelioma (HEH). To elucidate the etiology of HEH, particularly the microRNA (miRNA) profiles, tissue samples obtained from normal and tumor tissues were analyzed using a miRNA array system...
March 2017: Oncology Letters
https://www.readbyqxmd.com/read/28380190/primary-epithelioid-angiosarcoma-of-the-chest-wall-complicating-calcified-fibrothorax-and-mimicking-empyema-necessitates
#17
Luis Gorospe, Ana Patricia Ovejero-Díaz, Amparo Benito-Berlinches
No abstract text is available yet for this article.
January 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28326959/angiosarcoma-of-the-pelvis-in-a-13-year-old-girl
#18
Farah El-Sharkawy, Patricia Isabel Delgado, Antonello Podda, Holly Leigh Neville, Claudia Patricia Rojas
Angiosarcomas are highly aggressive malignancies of vascular origin and are very rarely found in children. We report a case of a 13-year-old girl with a history of abdominal pain and increased abdominal girth. Radiologic imaging showed significant ascites and large pelvic masses involving bilateral adnexa with abdominal spread. Microscopic examination of a biopsy revealed pleomorphic epithelioid and spindle cells with brisk mitotic activity, intracytoplasmic vacuoles, vascular channels, and large areas of hemorrhage and necrosis...
March 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/28293056/myoid-angioendothelioma-of-the-spleen-a-rare-case-report-and-literature-review
#19
Bita Geramizadeh, Mohammadhossein Anbardar, Seyed-Ali Malekhosseini
Most common tumors of the spleen are hematologic and lymphoid malignancies. Non-lymphoid and non-hematologic tumors of the spleen are very rare, the most common of which are vascular tumors. This group of tumors in the spleen is composed of heterogeneous tumors such as hemangioma, angioendothelioma (AE), littoral cell angioma, and angiosarcoma. There are several histologic forms of AE such as epithelioid AE, Kaposiform AE, and myoid AE. Among these splenic vascular tumors, myoid angioendothelioma (MAE) seems to be the least common type...
January 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28291558/-primary-epithelioid-adrenal-angiosarcoma-mimicking-undifferentiated-carcinoma
#20
Samira Miladi, Yaëlle Harrar, Maxime Battistella, Philippe Bertheau, Véronique Meignin, Brigitte Roche, Fatiha Amira Bouhidel
The adrenal primary epithelioid angiosarcoma (ASE) is a rare malignant tumor which can be histologically confused with other neoplasms. We report one case in a 79-year-old man who underwent adrenal tumor surgery for a mass fortuitly discovered by imaging for examination of an inflammatory syndrome associated with anemia. The histological diagnosis was difficult because of the undifferentiated and epithelioid appearance of tumor cells, whose immunohistochemical epithelial markers positivity led to frequent confusion with a metastatic carcinoma...
April 2017: Annales de Pathologie
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