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https://www.readbyqxmd.com/read/29665737/increased-synthesis-of-a-new-oleanane-type-saponin-in-hairy-roots-of-marigold-calendula-officinalis-after-treatment-with-jasmonic-acid
#1
Michał Markowski, Marek Długosz, Anna Szakiel, Mathieu Durli, Sophie Poinsignon, Sabine Bouguet-Bonnet, Lionel Vernex-Loset, Gabriel Krier, Max Henry
Native plant of marigold (Calendula officinalis L.) synthesizes oleanolic acid saponins classified as glucosides or glucuronides according to the first residue in sugar chain bound to C-3 hydroxyl group. Hairy root culture, obtained by transformation with Agrobacterium rhizogenes strain 15834, exhibit a potent ability of synthesis of oleanolic acid glycosides. The HPLC profile of saponin fraction obtained from C. officinalis hairy roots treated with plant stress hormone, jasmonic acid, showed the 10-times increase of the content of one particular compound, determined by NMR and MALDI TOF as a new bisdesmoside saponin, 3-O-β-d-glucuronopyranosyl-28-O-β-d-galactopyranosyl-oleanolic acid...
April 18, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29484986/characterization-of-biologically-active-substances-from-calendula-officinalis
#2
Petra Lovecka, Jan Lipov, Kamila Thumova, Anna Macurkova
BACKGROUND: The aim of this work was to compare water and organic extracts, infusions and tinctures from flowers and leaves of Calendula officinalis in terms of their biological activity and composition. The purpose of work was investigation whether the leaves and stems are really the waste or they contain interesting substances which could be utilized. Antimicrobial, antifungal, antioxidant and anti-inflammatory activities were studied. Then the ability to inhibit collagenase was studied as well...
February 26, 2018: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/29433250/edible-flowers-as-sources-of-phenolic-compounds-with-bioactive-potential
#3
Tânia C S P Pires, Maria Inês Dias, Lillian Barros, Ricardo C Calhelha, Maria José Alves, M Beatriz P P Oliveira, Celestino Santos-Buelga, Isabel C F R Ferreira
The edible flowers are widely used, but there is still a lot to be done in relation to its bioactive potential and its correlation with the presence of phenolic compounds. The aim of this study was determined the individual phenolic profile in the hydromethanolic extracts and infusion preparations of four different flower samples (Dahlia mignon, Rosa damascena 'Alexandria' and R. gallica 'Francesa' draft in R. canina, Calendula officinalis L., and Centaurea cyanus L.) and their bioactive potential (antioxidant, antiproliferative, and antibacterial capacity)...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29368902/-action-of-calendula-officinalis-essence-on-bone-preservation-after-the-extraction
#4
Laura K Uribe-Fentanes, Fernando Soriano-Padilla, Jorge Raúl Pérez-Frutos, Miriam Alejandra Veras-Hernandez
BACKGROUND: Calendula officinalis is a phytodrug used as analgesic, antiseptic and wound-healing agent due to its collagenogenic effect, which is why it is a convenient and affordable treatment that promotes alveolar bone preservation after tooth extraction in vivo. The aim of this study was to use Calendula officinalis during and after tooth extraction to determine its ability to preserve bone after this procedure. METHODS: We established two groups matched by age, gender and position of the third molar...
January 2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29349734/alternative-soilless-media-using-olive-mill-and-paper-waste-for-growing-ornamental-plants
#5
Antonios Chrysargyris, Omiros Antoniou, Andreas Tzionis, Munoo Prasad, Nikolaos Tzortzakis
Peat-based growing media are not ecologically sustainable and peat extraction threatens sensitive peatland ecosystem. In this study, olive-stone waste (OSW) and paper waste (PW) were used in different ratios-as growing media-for ornamental crop production, as peat (P) substitutes. Marigold (Calendula officinalis L.), petunia (Petunia x hybrita L.) and matthiola (Matthiola incana L.) plants were grown in (1) P (100%), (2) P:OSW (90%:10%), (3) P:OSW (70%:30%), and (4) P:OSW:PW (60%:20%:20%). The physicochemical properties of these substrates and the effects on plant growth were determined...
January 18, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29288400/anti-inflammatory-and-antiresorptive-effects-of-calendula-officinalis-on-inflammatory-bone-loss-in-rats
#6
Joanna Trycia M Alexandre, Luzia Hermínia Teixeira Sousa, Mario Roberto Pontes Lisboa, Flávia A C Furlaneto, Danielle Rocha do Val, Mirna Marques, Hellíada C Vasconcelos, Iracema Matos de Melo, Renata Leitão, Gerly Anne Castro Brito, Paula Goes
OBJECTIVE: The aim of this work was to evaluate the anti-inflammatory and antiresorptive effects of Calendula officinalis (CLO) on alveolar bone loss (ABL) in rats. MATERIAL AND METHODS: Male Wistar rats were subjected to ABL by ligature with nylon thread around the second upper left molar. The contralateral hemimaxillae were used as control. Rats received saline solution (SAL) or CLO (10, 30, or 90 mg/kg) 30 min before ligature and daily until the 11th day. The maxillae were removed and prepared for macroscopic, radiographic, micro-tomographic, histopathologic, histometric analysis, and immunohistochemical localization of receptor activator of nuclear factor kappa-B ligand (RANKL) and osteoprotegerin (OPG)...
December 29, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29197798/individual-and-combined-effects-of-fluoranthene-phenanthrene-mannitol-and-sulfuric-acid-on-marigold-calendula-officinalis
#7
Wahdatullah Khpalwak, Sherif M Abdel-Dayem, Hiroshi Sakugawa
A study was conducted to characterize marigold stress response to polycyclic aromatic hydrocarbons (PAHs) (oxidative stress inducers) with and without sulfuric acid (S.Acid; pH 3) (acid-stress inducer), and to evaluate reactive oxygen species (ROS) scavenging activity of mannitol (Mann). Marigold (Calendula officinalis) seedlings were grown in a greenhouse and fumigated with fluoranthene (FLU), phenanthrene (PHE), Mann, and S.Acid individually and in various combinations for 40 days. Various physiological and biochemical parameters among others were analyzed using standard methods...
February 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29191047/stealth-lipid-polymer-hybrid-nanoparticles-loaded-with-rutin-for-effective-brain-delivery-comparative-study-with-the-gold-standard-tween-80-optimization-characterization-and-biodistribution
#8
Rania A H Ishak, Nada M Mostafa, Amany O Kamel
The blood-brain barrier is considered the leading physiological obstacle hindering the transport of neurotherapeutics to brain cells. The application of nanotechnology coupled with surfactant coating is one of the efficacious tactics overcoming this barrier. The aim of this study was to develop lipid polymer hybrid nanoparticles (LPHNPs), composed of a polymeric core and a phospholipid shell entangled, for the first time, with PEG-based surfactants (SAA) viz. TPGS or Solutol HS 15 in comparison with the gold standard Tween 80, aiming to enhance brain delivery and escape opsonization...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28942136/traditional-wound-healing-plants-used-in-the-balkan-region-southeast-europe
#9
REVIEW
Snežana Jarić, Olga Kostić, Zorana Mataruga, Dragana Pavlović, Marija Pavlović, Miroslava Mitrović, Pavle Pavlović
ETHNOPHARMACOLOGICAL RELEVANCE: The geographical and ecological specificity of the Balkan Peninsula has resulted in the development of a distinct diversity of medicinal plants. In the traditional culture of the Balkan peoples, plants have medicinal, economic and anthropological/cultural importance, which is reflected in the sound knowledge of their diversity and use. This study analyses the traditional use of medicinal plants in the treatment of wounds and the pharmacological characteristics of the most frequently used species...
September 21, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28929051/comparison-of-effectiveness-of-calendula-officinalis-extract-gel-with-lycopene-gel-for-treatment-of-tobacco-induced-homogeneous-leukoplakia-a-randomized-clinical-trial
#10
Manisha Singh, Anjana Bagewadi
AIM: The aim of the study is to assess the efficacy of Calendula officinalis gel as cost-effective treatment modality in comparison to lycopene gel in the treatment of leukoplakia. MATERIALS AND METHODS: The study comprised of sixty patients of clinically diagnosed and histopathologically confirmed cases of homogeneous leukoplakia which were divided into Group I and Group II with thirty patients each. Group I patients were dispensed C. officinalis extract gel whereas Group II patients were given lycopene gel...
April 2017: International Journal of Pharmaceutical Investigation
https://www.readbyqxmd.com/read/28881197/oleanane-type-triterpene-saponins-from-calendula-stellata
#11
Meryem Lehbili, Abdulmagid Alabdul Magid, Ahmed Kabouche, Laurence Voutquenne-Nazabadioko, Amin Abedini, Hamid Morjani, Thomas Sarazin, Sophie C Gangloff, Zahia Kabouche
Five previously undescribed bisdesmosidic triterpenoid saponins named calendustellatosides A-E, along with fifteen known compounds were isolated from the 70% ethanol whole plant extract of Calendula stellata Cav. (Asteraceae). Their structures were determined by 1D- and 2D-NMR spectroscopy as well as high resolution mass spectrometry and acid hydrolysis. The saponins comprised oleanolic acid, echinocystic acid, morolic acid or mesembryanthemoidigenic acid as the aglycones and saccharide moieties at C-3 and C-28...
December 2017: Phytochemistry
https://www.readbyqxmd.com/read/28873765/greek-pdo-saffron-authentication-studies-using-species-specific-molecular-markers
#12
I Bosmali, S A Ordoudi, M Z Tsimidou, P Madesis
Saffron, the spice produced from the red stigmas of the flower of Crocus sativus L. is a frequent target of fraud and mislabeling practices that cannot be fully traced using the ISO 3632 trade standard specifications and test methods. A molecular approach is proposed herein as a promising branding strategy for the authentication of highly esteemed saffron brands such as the Greek Protected Designation of Origin (PDO) "Krokos Kozanis". Specific ISSR (inter-simple sequence repeat) markers were used to assess for the first time, the within species variability of several populations of C...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28864886/essential-oils-of-aromatic-egyptian-plants-repel-nymphs-of-the-tick-ixodes-ricinus-acari-ixodidae
#13
Hesham R El-Seedi, Muhammad Azeem, Nasr S Khalil, Hanem H Sakr, Shaden A M Khalifa, Khalijah Awang, Aamer Saeed, Mohamed A Farag, Mohamed F AlAjmi, Katinka Pålsson, Anna-Karin Borg-Karlson
Due to the role of Ixodes ricinus (L.) (Acari: Ixodidae) in the transmission of many serious pathogens, personal protection against bites of this tick is essential. In the present study the essential oils from 11 aromatic Egyptian plants were isolated and their repellent activity against I. ricinus nymphs was evaluated Three oils (i.e. Conyza dioscoridis L., Artemisia herba-alba Asso and Calendula officinalis L.) elicited high repellent activity in vitro of 94, 84.2 and 82%, respectively. The most active essential oil (C...
September 2017: Experimental & Applied Acarology
https://www.readbyqxmd.com/read/28767066/isorhamnetin-and-quercetin-derivatives-as-anti-acetylcholinesterase-principles-of-marigold-calendula-officinalis-flowers-and-preparations
#14
Daniil N Olennikov, Nina I Kashchenko, Nadezhda K Chirikova, Anzurat Akobirshoeva, Ifrat N Zilfikarov, Cecile Vennos
Marigold (Calendula officinalis L.) is one of the most common and widespread plants used medicinally all over the world. The present study aimed to evaluate the anti-acetylcholinesterase activity of marigold flowers, detect the compounds responsible and perform chemical analysis of marigold commercial products. Analysis of 23 varieties of C. officinalis flowers introduced into Siberia allowed us to select the Greenheart Orange variety due to the superior content of flavonoids (46.87 mg/g) and the highest inhibitory activity against acetylcholinesterase (IC50 63...
August 2, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28705585/a-four-dimensional-separation-method-based-on-continuous-heart-cutting-gas-chromatography-with-ion-mobility-and-high-resolution-mass-spectrometry
#15
Christian Lipok, Jörg Hippler, Oliver J Schmitz
A two-dimensional GC (2D-GC) method was developed and coupled to an ion mobility-high resolution mass spectrometer, which enables the separation of complex samples in four dimensions (2D-GC, ion mobilility spectrometry and mass spectrometry). This approach works as a continuous multiheart-cutting GC-system (GC+GC), using a long modulation time of 20s, which allows the complete transfer of most of the first dimension peaks to the second dimension column without fractionation, in comparison to comprehensive two-dimensional gas chromatography (GCxGC)...
July 8, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28701962/the-effect-of-calendula-officinalis-on-oxidative-stress-and-bone-loss-in-experimental-periodontitis
#16
Mariana Dos Reis Lima, Amanda P Lopes, Conceição Martins, Gerly A C Brito, Virgínia C Carneiro, Paula Goes
Periodontitis is associated with reduced antioxidant capacity and increased oxidative damage. Oxidative stress induces inflammation and bone loss contributing to the pathological progression of periodontal disease. Calendula officinalis (CLO) has demonstrated anti-inflammatory and anti-oxidant activities. Therefore, the aim of this study was to evaluate the effect of CLO on oxidative stress and bone loss in rats subjected to experimental periodontitis (EP). For this, 72 male Wistar rats were divided into groups: Naïve, Saline (SAL) and CLO...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28679180/a-phase-ii-randomized-single-blinded-placebo-controlled-clinical-trial-on-the-efficacy-of-curcumina-and-calendula-suppositories-for-the-treatment-of-patients-with-chronic-prostatitis-chronic-pelvic-pain-syndrome-type-iii
#17
RANDOMIZED CONTROLLED TRIAL
Giuseppe Morgia, Giorgio Ivan Russo, Daniele Urzì, Salvatore Privitera, Tommaso Castelli, Vincenzo Favilla, Sebastiano Cimino
OBJECTIVE: The management of chronic prostatitis/ chronic pelvic pain syndrome type III (CP/CPPS) has been always considered complex due to several biopsychological factors underling the disease. In this clinical study, we aimed to evaluate the efficacy of the treatment with Curcumin and Calendula extract in patients with CP/CPPS III. MATERIAL AND METHODS: From June 2015 to January 2016 we enrolled 60 consecutive patients affected by CP/CPPS III in our institution...
June 30, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28560780/double-blind-randomized-phase-iii-study-comparing-a-mixture-of-natural-agents-versus-placebo-in-the-prevention-of-acute-mucositis-during-chemoradiotherapy-for-head-and-neck-cancer
#18
Laura Marucci, Alessia Farneti, Paolo Di Ridolfi, Paola Pinnaro, Raul Pellini, Diana Giannarelli, Patrizia Vici, Mario Conte, Valeria Landoni, Giuseppe Sanguineti
BACKGROUND: There is no widely accepted intervention in the prevention of acute mucositis during chemoradiotherapy for head and neck carcinoma. In the present double-blind study, we tested 4 natural agents, propolis, aloe vera, calendula, and chamomile versus placebo. METHODS: Patients undergoing concomitant chemo-intensity-modulated radiotherapy (IMRT) were given natural agent or matched placebo; grade 3 mucositis on physical examination according to Common Terminology Criteria for Adverse Events (CTCAE) version 3...
May 31, 2017: Head & Neck
https://www.readbyqxmd.com/read/28421562/prevention-of-bacterial-biofilm-formation-on-soft-contact-lenses-using-natural-compounds
#19
Amira M El-Ganiny, Ghada H Shaker, Abeer A Aboelazm, Heba A El-Dash
PURPOSE: In eye care field, contact lenses (CL) have a great impact on improving vision, but their use can be limited by ocular infection. CL- associated infections can be reduced by good attention to CL storage case practice. CL-care solutions should be able to control microbial growth on CL. The aim of the study was to evaluate and compare the efficacy of CL-care solutions (found in Egyptian market) with some natural compounds in removal and inhibition of bacterial biofilm formed on soft CL...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28335791/fischer-s-plants-in-folk-beliefs-and-customs-a-previously-unknown-contribution-to-the-ethnobotany-of-the-polish-lithuanian-belarusian-borderland
#20
Monika Kujawska, Piotr Klepacki, Łukasz Łuczaj
BACKGROUND: Historical ethnobotanical studies are useful starting points for further diachronic analysis. The aim of this contribution is to present archival data from the Polish-Lithuanian-Belarusian borderland, which were collected by Adam Fischer, a Polish ethnographer from Lviv, in the 1930s. These data were originally gathered for publication in the first part of the Lexicon of Slavic beliefs and customs, dedicated to plant uses in traditional Slavonic culture. It was intended to be a joint international enterprise, but was never actually fulfilled...
March 23, 2017: Journal of Ethnobiology and Ethnomedicine
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