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Ana Flávia Machado de Carvalho, Maura Cristina Porto Feitosa, Nayana Pinheiro Machado de Freitas Coelho, Veruska Cronemberger Nogueira Rebêlo, Juçara Gonçalves de Castro, Patrícia Regina Gomes de Sousa, Valrian Campos Feitosa, Emilia Angela Lo Schiavo Arisawa
OBJECTIVE: To evaluate the effects of low-level laser therapy isolated and associated with Calendula officinalis oil in treating diabetic foot ulcers. METHOD: An experimental, randomized, controlled, prospective, interventional clinical case study using a quantitative approach. The sample consisted of 32 diabetic patients of both genders. Participants were randomly divided into four groups. Doppler Ultrasound evaluation of the Ankle-Brachial Index, brief pain inventory and analog pain scale were performed at baseline and after 30 days...
July 2016: Revista da Escola de Enfermagem da U S P
Shariq Qayyum, Asad Ullah Khan
Silver nanoparticles (AgNPs) were biosynthesized via a green route using ten different plants extracts (GNP1- Caryota urens, GNP2-Pongamia glabra, GNP3- Hamelia patens, GNP4-Thevetia peruviana, GNP5-Calendula officinalis, GNP6-Tectona grandis, GNP7-Ficus petiolaris, GNP8- Ficus busking, GNP9- Juniper communis, GNP10-Bauhinia purpurea). AgNPs were tested against drug resistant microbes and their biofilms. These nanoparticles (NPs) were characterised using UV-vis spectroscopy, transmission electron microscope, Fourier transform infrared spectroscopy, X-ray diffraction and Image J software...
October 2016: IET Nanobiotechnology
Laila Midhat, Naaila Ouazzani, Mouhsine Esshaimi, Ahmed Ouhammou, Laila Mandi
The present paper aims to perform a screening of native plants growing in Kettara mine-Marrakech (Southern Morocco) for its phytoremediation. Plants and soil samples were collected and analyzed for Pb, Zn, Cu and Cd concentrations at several sites in the mine. The results showed that the soil in the vicinity of Kettara mine is deficient in major elements and contain toxic levels of metals. Spontaneously growing native plants were botanically identified then classified into 21 species and 14 families. Significant difference was observed among the average concentrations of four heavy metals (Pb, Zn, Cu and Cd) in plants (P ≤ 0...
August 23, 2016: International Journal of Phytoremediation
Rachel T Buxton, Emma Brown, Lewis Sharman, Christine M Gabriele, Megan F McKenna
Monitoring patterns in biodiversity and phenology have become increasingly important given accelerating levels of anthropogenic change. Long-term monitoring programs have reported earlier occurrence of spring activity, reflecting species response to climate change. Although tracking shifts in spring migration represents a valuable approach to monitoring community-level consequences of climate change, robust long-term observations are challenging and costly. Audio recordings and metrics of bioacoustic activity could provide an effective method for monitoring changes in songbird activity and broader biotic interactions...
July 2016: Ecology and Evolution
Marzena Wyganowska-Swiatkowska, Paulina Urbaniak, Anna Szkaradkiewicz, Jerzy Jankun, Malgorzata Kotwicka
Antiseptic rinses have been successfully used in inflammatory states of the gums and oral cavity mucosa. Antibacterial effects of chlorhexidine, essential oils and some herbs are well documented. Reaction of host tissue to these substances has much poorer documentation. The aim of the study was to analyse the influence of chlorhexidine (CHX), essential oil (EO: thymol, 0.064%; eucalyptol, 0.092%; methyl salicylate, 0.060%; menthol, 0.042%) mouth rinses and salvia, chamomile and calendula brews on fibroblast biology in vitro...
2016: Central-European Journal of Immunology
C G Venturinil, A Bruinsmann, C P Oliveira, R V Contri, A R Pohlmann, S S Guterres
An innovative nanocapsule formulation for parenteral administration using selected vegetable oils (mango, jojoba, pequi, oat, annatto, calendula, and chamomile) was developed that has the potential to encapsulate various drugs. The vegetable oil-loaded nanocapsules were prepared by interfacial deposition and compared with capric/caprylic triglyceride-loaded lipid core nanocapsules. The major objective was to investigate the effect of vegetable oils on particle size distribution and physical stability and to determine the hemolytic potential of the nanocapsules, considering their applicability for intravenous administration...
February 2016: Journal of Nanoscience and Nanotechnology
Yin-Pin Cheng, Chia-Ying Ke, Chih-Chieh Kuo, Yih-Jing Lee
Several retinal degenerative diseases cause vision loss and retinal cell death. Currently, people face prolonged exposure to digital screens, rendering vision protection from light exposure a critical topic. In this study, we designed a complex lutein formula (CLF) by combining several natural compounds: Calendula officinalis, Lycium barbarum, Vaccinium myrtillus, Cassia obtusifolia, and Rhodiola rosea. In addition, we evaluated the protective effects of the formula on retinal functions in an animal model for light-induced retinal degeneration...
August 31, 2016: Chinese Journal of Physiology
Manikarna Dinda, Swagata Mazumdar, Saurabh Das, Durba Ganguly, Uma B Dasgupta, Ananya Dutta, Kuladip Jana, Parimal Karmakar
The active fraction and/or compounds of Calendula officinalis responsible for wound healing are not known yet. In this work we studied the molecular target of C. officinalis hydroethanol extract (CEE) and its active fraction (water fraction of hydroethanol extract, WCEE) on primary human dermal fibroblasts (HDF). In vivo, CEE or WCEE were topically applied on excisional wounds of BALB/c mice and the rate of wound contraction and immunohistological studies were carried out. We found that CEE and only its WCEE significantly stimulated the proliferation as well as the migration of HDF cells...
July 18, 2016: Phytotherapy Research: PTR
Jagdeep Kaur, Shabir Sidhu, Kanwaljit Chopra, M U Khan
CONTEXT: Calendula officinalis L. (Asteraceae) has been traditionally used in treating inflammation of internal organs, gastrointestinal tract ulcers and wound healing. OBJECTIVE: The present study investigates the effect of ethanol extract (95%) of Calendula officinalis flowers in l-arginine induced acute necrotizing pancreatitis in rats. MATERIALS AND METHODS: Rats were divided into four groups: normal control, l-arginine control, Calendula officinalis extract (COE) treated and melatonin treated (positive control), which were further divided into subgroups (24 h, day 3 and 14) according to time points...
June 23, 2016: Pharmaceutical Biology
Miroslava Císarová, Dana Tančinová, Juraj Medo, Miroslava Kačániová
The aim of the present study was to assess the antifungal and anti-toxinogenic activity of 15 essential oils (EOs) against three fungi of the genus Aspergillus (A. parasiticus KMi-227-LR, A. parasiticus KMi-220-LR and A. flavus KMi-202-LR). The minimum inhibitory doses (MIDs) of the tested essential oils and their antifungal activity were determined using the micro-atmosphere method. The original commercial essential oil samples of Jasminum officinale L., Thymus vulgaris L., Syzygium aromaticum (L.) Merrill & Perry, Rosmarinus officinalis L...
June 20, 2016: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
Marcelo Buzzi, Franciele de Freitas, Marcos de Barros Winter
No abstract text is available yet for this article.
March 2016: Revista Brasileira de Enfermagem
M Isabel Calvo, Rita Yolanda Cavero
ETHNOPHARMACOLOGICAL RELEVANCE: Several plants have been found to have effective against number of ophthalmological problems in Navarra. MATERIAL AND METHODS: Information was collected using semi-structured ethnobotanical interviews with 686 informants in 267 locations. In order to confirm the pharmacological application of the uses more cited by the informants, a literature review was conducted. RESULTS: A total of 57 pharmaceutical uses were reported, for 19 plants and 13 families, mainly represented by Asteraceae...
August 22, 2016: Journal of Ethnopharmacology
Zhenguo Du, Wenzhong Lin, Ping Qiu, Xiaojuan Liu, Lingfang Guo, Kangcheng Wu, Songbai Zhang, Zujian Wu
A double-stranded RNA (dsRNA) HBJZ1506 recovered from the phytopathogenic fungus Erysiphe cichoracearum infecting Calendula officinalis in Jingzhou, Hubei Province, China, was sequenced. HBJZ1506 comprises 11,908 nucleotides (nt) and contains a 11,859-nt-long open reading frame (ORF) coding for a polypeptide that is 61 % identical to that of a putative endornavirus named grapevine endophyte endornavirus (GeEV). The putative polyprotein has an RNA-dependent RNA polymerase (RdRp) domain and an RNA helicase domain, which show homology to and have an arrangement that is similar to that of their counterparts in approved or putative endornaviruses...
August 2016: Archives of Virology
Y I El-Nashar, A A Asrar
Chemical mutagenesis is an efficient tool used in mutation-breeding programs to improve the vital characters of the floricultural crops. This study aimed to estimate the effects of different concentrations of two chemical mutagens; sodium azide (SA) and diethyl sulfate (DES). The vegetative growth and flowering characteristics in two generations (M1 and M2) of calendula plants were investigated. Seeds were treated with five different concentrations of SA and DES (at the same rates) of 1000, 2000, 3000, 4000, and 5000 ppm, in addition to a control treatment of 0 ppm...
2016: Genetics and Molecular Research: GMR
Y I El-Nashar, M H Ammar
Six different colchicine concentrations: 0, 400, 800, 1200, 1600, and 2000 ppm, in combination with four soaking time treatments (1, 2, 3, and 4 h), were selected to assess the effects on germination, vegetative growth, and flower yield components in calendula plants. The molecular diversity among the treatments was assessed using ten SRAP marker combinations. Seed soaking in colchicine significantly enhanced both the fresh and the dry shoot and root masses, flowering date, number of flowers per plant, and flower diameter...
2016: Genetics and Molecular Research: GMR
Maria Lourdes Leite Moraes, Heron Dominguez Torres da Silva, Lucas Blanes, Philip Doble, Marina Franco Maggi Tavares
The application of Design of Experiments (DoE) to the determination of optimum conditions for an extraction process relies on the correct selection of mathematical models. The linear model is the one typically used; however, in some cases it does not always have superior performance, ignoring the real nature of the data and its appropriate descriptive model. In order to evaluate the extraction efficiency of isorhamnetin-3-O-rutinoside from flowers of Calendula officinalis L. a multivariate factorial analysis was used...
June 5, 2016: Journal of Pharmaceutical and Biomedical Analysis
María Miguel, Lillian Barros, Carla Pereira, Ricardo C Calhelha, Pablo A Garcia, MaÁngeles Castro, Celestino Santos-Buelga, Isabel C F R Ferreira
The chemical composition and bioactive properties of two plants (Calendula officinalis L. and Mentha cervina L.) were studied. Their nutritional value revealed a high content of carbohydrates and low fat levels, and very similar energy values. However, they presented different profiles in phenolic compounds and fatty acids; C. officinalis presented mainly glycosylated flavonols and saturated fatty acids, while M. cervina presented mainly caffeoyl derivatives and polyunsaturated fatty acids. M. cervina showed the highest concentration of phenolic compounds while C...
May 18, 2016: Food & Function
Marcelo Buzzi, Franciele de Freitas, Marcos Winter
Diabetic foot ulcers (DFUs) have a significant impact on patient quality of life. A prospective, descriptive pilot study was conducted between May 2012 and December 2013 through the dermatology outpatient unit in a Brazilian hospital to evaluate the clinical benefits of using Calendula officinalis hydroglycolic extract in the treatment of DFUs. Patients diagnosed with a stable neuropathic ulcer of >3 months' duration; ranging in size from 0.5-40 cm(2); without osteomyelitis, gangrene, bone exposure, cancer, or deep tissue infection; ages 18-90 years; with adequate glycemic control and no history of an allergy to C...
March 2016: Ostomy/wound Management
Giovanna Soffritti, Matteo Busconi, Rosa Ana Sánchez, Jean-Marie Thiercelin, Moschos Polissiou, Marta Roldán, José Antonio Fernández
Saffron (Crocus sativus L.) is very expensive and, because of this, often subject to adulteration. Modern genetic fingerprinting techniques are an alternative low cost technology to the existing chemical techniques, which are used to control the purity of food products. Buddleja officinalis Maxim, Gardenia jasminoides Ellis, Curcuma longa L., Carthamus tinctorius L. and Calendula officinalis L. are among the most frequently-used adulterants in saffron spice. Three commercial kits were compared concerning the ability to recover PCR-grade DNA from saffron, truly adulterated samples and possible adulterants, with a clear difference among them, mainly with the processed samples...
2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Seyyed Mohammad-Kazem Nourbakhsh, Hojjatollah Rouhi-Boroujeni, Maryam Kheiri, Mahmoud Mobasheri, Majid Shirani, Saeedeh Ahrani, Javad Karami, Zahra Keivani Hafshejani
INTRODUCTION: Diaper dermatitis is referred to the inflammation in outer layers of the skin in the perineal area, lower abdomen, and inner thighs. The lesions are maculopapular and usually itchy, which could cause bacterial or candida infection, and predispose the infants to penis or vaginal and urinary infection and lead to discomfort, irritability, and restlessness. The drugs which have been so far administered for this disease (topical steroids) cause special complications for the sensitive skin in this area...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
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