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https://www.readbyqxmd.com/read/28767066/isorhamnetin-and-quercetin-derivatives-as-anti-acetylcholinesterase-principles-of-marigold-calendula-officinalis-flowers-and-preparations
#1
Daniil N Olennikov, Nina I Kashchenko, Nadezhda K Chirikova, Anzurat Akobirshoeva, Ifrat N Zilfikarov, Cecile Vennos
Marigold (Calendula officinalis L.) is one of the most common and widespread plants used medicinally all over the world. The present study aimed to evaluate the anti-acetylcholinesterase activity of marigold flowers, detect the compounds responsible and perform chemical analysis of marigold commercial products. Analysis of 23 varieties of C. officinalis flowers introduced into Siberia allowed us to select the Greenheart Orange variety due to the superior content of flavonoids (46.87 mg/g) and the highest inhibitory activity against acetylcholinesterase (IC50 63...
August 2, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28705585/a-four-dimensional-separation-method-based-on-continuous-heart-cutting-gas-chromatography-with-ion-mobility-and-high-resolution-mass-spectrometry
#2
Christian Lipok, Jörg Hippler, Oliver J Schmitz
A two-dimensional GC (2D-GC) method was developed and coupled to an ion mobility-high resolution mass spectrometer, which enables the separation of complex samples in four dimensions (2D-GC, ion mobilility spectrometry and mass spectrometry). This approach works as a continuous multiheart-cutting GC-system (GC+GC), using a long modulation time of 20s, which allows the complete transfer of most of the first dimension peaks to the second dimension column without fractionation, in comparison to comprehensive two-dimensional gas chromatography (GCxGC)...
July 8, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28701962/the-effect-of-calendula-officinalis-on-oxidative-stress-and-bone-loss-in-experimental-periodontitis
#3
Mariana Dos Reis Lima, Amanda P Lopes, Conceição Martins, Gerly A C Brito, Virgínia C Carneiro, Paula Goes
Periodontitis is associated with reduced antioxidant capacity and increased oxidative damage. Oxidative stress induces inflammation and bone loss contributing to the pathological progression of periodontal disease. Calendula officinalis (CLO) has demonstrated anti-inflammatory and anti-oxidant activities. Therefore, the aim of this study was to evaluate the effect of CLO on oxidative stress and bone loss in rats subjected to experimental periodontitis (EP). For this, 72 male Wistar rats were divided into groups: Naïve, Saline (SAL) and CLO...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28679180/a-phase-ii-randomized-single-blinded-placebo-controlled-clinical-trial-on-the-efficacy-of-curcumina-and-calendula-suppositories-for-the-treatment-of-patients-with-chronic-prostatitis-chronic-pelvic-pain-syndrome-type-iii
#4
Giuseppe Morgia, Giorgio Ivan Russo, Daniele Urzì, Salvatore Privitera, Tommaso Castelli, Vincenzo Favilla, Sebastiano Cimino
OBJECTIVE: The management of chronic prostatitis/ chronic pelvic pain syndrome type III (CP/CPPS) has been always considered complex due to several biopsychological factors underling the disease. In this clinical study, we aimed to evaluate the efficacy of the treatment with Curcumin and Calendula extract in patients with CP/CPPS III. MATERIAL AND METHODS: From June 2015 to January 2016 we enrolled 60 consecutive patients affected by CP/CPPS III in our institution...
June 30, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28560780/double-blind-randomized-phase-iii-study-comparing-a-mixture-of-natural-agents-versus-placebo-in-the-prevention-of-acute-mucositis-during-chemoradiotherapy-for-head-and-neck-cancer
#5
Laura Marucci, Alessia Farneti, Paolo Di Ridolfi, Paola Pinnaro, Raul Pellini, Diana Giannarelli, Patrizia Vici, Mario Conte, Valeria Landoni, Giuseppe Sanguineti
BACKGROUND: There is no widely accepted intervention in the prevention of acute mucositis during chemoradiotherapy for head and neck carcinoma. In the present double-blind study, we tested 4 natural agents, propolis, aloe vera, calendula, and chamomile versus placebo. METHODS: Patients undergoing concomitant chemo-intensity-modulated radiotherapy (IMRT) were given natural agent or matched placebo; grade 3 mucositis on physical examination according to Common Terminology Criteria for Adverse Events (CTCAE) version 3...
May 31, 2017: Head & Neck
https://www.readbyqxmd.com/read/28421562/prevention-of-bacterial-biofilm-formation-on-soft-contact-lenses-using-natural-compounds
#6
Amira M El-Ganiny, Ghada H Shaker, Abeer A Aboelazm, Heba A El-Dash
PURPOSE: In eye care field, contact lenses (CL) have a great impact on improving vision, but their use can be limited by ocular infection. CL- associated infections can be reduced by good attention to CL storage case practice. CL-care solutions should be able to control microbial growth on CL. The aim of the study was to evaluate and compare the efficacy of CL-care solutions (found in Egyptian market) with some natural compounds in removal and inhibition of bacterial biofilm formed on soft CL...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28335791/fischer-s-plants-in-folk-beliefs-and-customs-a-previously-unknown-contribution-to-the-ethnobotany-of-the-polish-lithuanian-belarusian-borderland
#7
Monika Kujawska, Piotr Klepacki, Łukasz Łuczaj
BACKGROUND: Historical ethnobotanical studies are useful starting points for further diachronic analysis. The aim of this contribution is to present archival data from the Polish-Lithuanian-Belarusian borderland, which were collected by Adam Fischer, a Polish ethnographer from Lviv, in the 1930s. These data were originally gathered for publication in the first part of the Lexicon of Slavic beliefs and customs, dedicated to plant uses in traditional Slavonic culture. It was intended to be a joint international enterprise, but was never actually fulfilled...
March 23, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28109063/chemical-variability-antioxidant-and-antifungal-activities-of-essential-oils-and-hydrosol-extract-of-calendula-arvensis-l-from-western-algeria
#8
Rania Belabbes, Mohammed El Amine Dib, Nassim Djabou, Faiza Ilias, Boufeldja Tabti, Jean Costa, Alain Muselli
The chemical composition of the essential oils and hydrosol extract from aerial parts of Calendula arvensis L. was investigated using GC-FID and GC/MS. Intra-species variations of the chemical compositions of essential oils from 18 Algerian sample locations were investigated using statistical analysis. Chemical analysis allowed the identification of 53 compounds amounting to 92.3 - 98.5% with yields varied of 0.09 - 0.36% and the main compounds were zingiberenol 1 (8.7 - 29.8%), eremoligenol (4.2 - 12...
May 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28105900/feasibility-acceptability-and-tolerability-of-rgn107-in-the-palliative-wound-care-management-of-chronic-wound-symptoms
#9
M Madisetti, T J Kelechi, M Mueller, E J Amella, M A Prentice
OBJECTIVE: To assess the feasibility, acceptability and tolerability of RGN107 use, a natural powder blend of Arnica Montana, Calendula Officinalis, Mentha Arvensis and Santalum Album, among hospice patients and their wound caregivers in the palliative wound care management of chronic wound symptoms at end-of-life. METHOD: Data were collected between May 2013 and November 2015. A pilot trial conducted among 50 hospice patients with symptomatic (pain, odour, or exudate) chronic wounds...
January 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28101823/biological-activities-of-asteraceae-achillea-millefolium-and-calendula-officinalis-and-lamiaceae-melissa-officinalis-and-origanum-majorana-plant-extracts
#10
Mónica R García-Risco, Lamia Mouhid, Lilia Salas-Pérez, Alexis López-Padilla, Susana Santoyo, Laura Jaime, Ana Ramírez de Molina, Guillermo Reglero, Tiziana Fornari
Asteraceae (Achillea millefolium and Calendula officinalis) and Lamiaceae (Melissa officinalis and Origanum majorana) extracts were obtained by applying two sequential extraction processes: supercritical fluid extraction with carbon dioxide, followed by ultrasonic assisted extraction using green solvents (ethanol and ethanol:water 50:50). The extracts were analyzed in terms of the total content of phenolic compounds and the content of flavonoids; the volatile oil composition of supercritical extracts was analyzed by gas chromatography and the antioxidant capacity and cell toxicity was determined...
March 2017: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/28011127/anticandidal-antibacterial-cytotoxic-and-antioxidant-activities-of-calendula-arvensis-flowers
#11
A-M Abudunia, I Marmouzi, M E A Faouzi, Y Ramli, J Taoufik, N El Madani, E M Essassi, A Salama, K Khedid, M Ansar, A Ibrahimi
Calendula arvensis (CA) is one of the important plants used in traditional medicine in Morocco, due to its interesting chemical composition. The present study aimed to determine the anticandidal, antioxidant and antibacterial activities, and the effects of extracts of CA flowers on the growth of myeloid cancer cells. Also, to characterize the chemical composition of the plant. Flowers of CA were collected based on ethnopharmacological information from the villages around the region Rabat-Khemisset, Moroccco...
December 20, 2016: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/27976220/production-of-calendula-in-m%C3%A3-xico-and-accumulation-of-secondary-metabolites
#12
M Palma Tenango, M Soto Hernández, V González Hernández
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27974009/therapeutic-effectiveness-of-a-calendula-officinalis-extract-in-venous-leg-ulcer-healing
#13
M Buzzi, F de Freitas, M de Barros Winter
OBJECTIVE: Non-healing venous leg ulcers (VLUs) have a significant effect on patients' quality of life and substantially increase expenditures in health-care systems. The aim of this study was to evaluate the clinical efficacy of the Calendula officinalis extract, Plenusdermax, in the treatment of VLUs. METHOD: Patients treated with Calendula officinalis extract (n=38) and control patients (n=19) were evaluated every two weeks for 30 weeks or until their ulcers healed...
December 2, 2016: Journal of Wound Care
https://www.readbyqxmd.com/read/27956358/in-vitro-studies-to-evaluate-the-wound-healing-properties-of-calendula-officinalis-extracts
#14
Christoph Nicolaus, Susanne Junghanns, Anja Hartmann, Renato Murillo, Markus Ganzera, Irmgard Merfort
ETHNOPHARMACOLOGICAL RELEVANCE: Calendula officinalis (pot marigold) flower extracts have a long-lasting tradition in ethnopharmacology. Currently, the European Medicines Agency (EMA) has approved its lipophilic and aqueous alcoholic extracts as traditional medicinal products for the treatment of minor inflammation of the skin and as an aid in the healing of minor wounds. AIM OF THE STUDY: The purpose of this study was to analyse the molecular mechanism of the wound healing effects of Calendula extracts, which may reflect the phytomedicines currently used in the market...
January 20, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27889336/characterization-of-natural-polymers-from-jackfruit-pulp-calendula-flowers-and-tara-seeds-as-mucoadhesive-and-controlled-release-components-in-buccal-tablets
#15
Vidya Sabale, Archana Paranjape, Vandana Patel, Prafulla Sabale
Identification and physiochemical parameters such as solubility, loss on drying, viscosity, pH, swelling index, starch and gum constituents were determined in natural polymers and showed satisfactory results. Spectral studies established the compatibility of natural polymers. The drug release kinetics in preliminary trial batches showed that tablets containing natural mucilages and gum showed a prolonged drug release comparable to Carbopol 974P and Methocel K4M. Also, all tablets showed a satisfactory drug permeability flux...
February 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27880086/comparing-the-effects-of-calendula-officinalis-and-clotrimazole-on-vaginal-candidiasis-a-randomized-controlled-trial
#16
Elnaz Saffari, Sakineh Mohammad-Alizadeh-Charandabi, Mohammad Adibpour, Mojgan Mirghafourvand, Yousef Javadzadeh
This triple-blind trial examined the effects of Calendula officinalis vaginal cream on the treatment of vaginal Candidiasis (primary outcome) and sexual function (secondary outcome). Married women aged 18-45 years with vaginal Candidiasis (n = 150) were recruited from April to October 2014 and randomized into Calendula and clotrimazole groups, using 5-g vaginal cream every night for seven nights. Clinical and laboratory assessments were conducted at 10-15 and 30-35 days after intervention and the female sexual function index was assessed at 30-35 days...
November 23, 2016: Women & Health
https://www.readbyqxmd.com/read/27860184/using-calendula-officinalis-as-a-floral-resource-to-enhance-aphid-and-thrips-suppression-by-the-flower-bug-orius-sauteri-hemiptera-anthocoridae
#17
Jing Zhao, Xiaojun Guo, Xiaoling Tan, Nicolas Desneux, Lucia Zappala, Fan Zhang, Su Wang
BACKGROUND: The flower bug Orius sauteri (Poppius) (Hemiptera: Anthocoridae) is widely used as a biocontrol agent against thrips and aphids infesting greenhouse vegetables in Asia. The survival and oviposition of such predators, as well as the biocontrol services they provide, may be enhanced by adding extra floral resources to the crops. In the present study we investigated the effects of the plant Calendula officinalis L., used as a floral resource, for promoting the control of Myzus persicae (Sulzer) and Frankliniella occidentalis (Pergande) by O...
March 2017: Pest Management Science
https://www.readbyqxmd.com/read/27855909/nutritional-and-chemical-characterization-of-edible-petals-and-corresponding-infusions-valorization-as-new-food-ingredients
#18
Tânia C S P Pires, Maria Inês Dias, Lillian Barros, Isabel C F R Ferreira
Edible flowers provide new colours, textures and vibrancy to any dish, and apart from the "glam" factor, they can constitute new sources of bioactive compounds. In the present work, the edible petals and infusions of dahlia, rose, calendula and centaurea, were characterized regarding their nutritional value and composition in terms of hydrophilic and lipophilic compounds. Carbohydrates were the most abundant macronutrients, followed by proteins and ash. Fructose, glucose and sucrose were identified in all the petals and infusions...
April 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27796089/bioaccessibility-and-antioxidant-activity-of-calendula-officinalis-supercritical-extract-as-affected-by-in-vitro-codigestion-with-olive-oil
#19
Diana Martin, Joaquín Navarro Del Hierro, David Villanueva Bermejo, Ramón Fernández-Ruiz, Tiziana Fornari, Guillermo Reglero
Supercritical extracts of marigold (ME) were produced and characterized. The bioaccessibility of terpenes, especially that of pentacyclic triterpenes (PT), the particle-size distribution, and antioxidant activity after the in vitro codigestion of ME with olive oil (OO) were determined. ME produced without cosolvent was richer in taraxasterol, lupeol, α-amyrin, and β-amyrin than extracts with cosolvent. All terpenes showed high bioaccessibility without OO (>75%). Significant correlations were found between the molecular properties of compounds (logP and number of rotatable bonds) and their bioaccessibility...
November 23, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27768020/clinical-efficacy-of-a-solution-composed-by-sodium-bicarbonate-and-alginate-aloe-vera-propoli-chamomile-calendula-and-honey-in-the-treatment-of-minor-recurrent-aphthous-stomatitis-in-children
#20
Elena Bardellini, Francesca Amadori, Giulio Conti, Alessandra Majorana
No abstract text is available yet for this article.
December 2016: Minerva Pediatrica
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