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EBUS-TBNA

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https://www.readbyqxmd.com/read/29675060/utility-and-safety-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-in-patients-with-mediastinal-and-hilar-lymphadenopathy-western-region-experience
#1
Ahmed A Aljohaney
AIMS: The aim of the study was to evaluate the clinical utility and safety of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with mediastinal and hilar lymphadenopathy and to explicitly describe the utility of this procedure in patient's outcome. METHODS: A retrospective review and analysis was conducted on 52 patients with mediastinal or hilar lymphadenopathy who underwent EBUS-TBNA from June 2012 to June 2016. All the patients were evaluated by computed tomography (CT) chest with contrast before EBUS examination...
April 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29666815/endobronchial-ultrasound-transbronchial-needle-aspiration-ebus-tbna-a-diagnostic-challenge-for-mediastinal-lesions
#2
REVIEW
Duilio Divisi, Gino Zaccagna, Mirko Barone, Francesca Gabriele, Roberto Crisci
Lung cancer is one of the most frequent neoplastic diseases. To date, most lung cancer is diagnosed at an advanced stage, making it difficult to choose the diagnostic and therapeutic strategy. Surgical resection represents the best therapeutic solution. However, the best results are obtained only in the early stages of the disease. Lymph node involvement conditions the treatment (surgical or non-surgical approach). Mediastinoscopy is an effective and widely used method for mediastinal staging but does not allow us to reach many mediastinal lymph nodes...
March 2018: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29666703/sarcoid-like-mediastinal-lymphadenopathy-in-gynecologic-malignancy
#3
Bilal H Lashari, Megumi Asai, Gissele Randleman, Martha Sack, Rajeshkumar Patel
Noncaseating granulomas are seen surrounding tumors with varying frequency, possibly as part of an immune response to tumor cells. However, data about the association of sarcoid with gynecologic malignancy is sparse. We performed a search of our institutional database for all EBUS-TBNA biopsies conducted within the past five years that revealed granulomatous inflammation. All adult female patients with a history of gynecologic malignancy were included. Patients with a history of sarcoidosis or fungal or mycobacterial infection were excluded...
2018: Pulmonary Medicine
https://www.readbyqxmd.com/read/29664760/effect-of-routine-clopidogrel-use-on-bleeding-complications-after-endobronchial-ultrasound-guided-fine-needle-aspiration
#4
Tracey N Webb, Eric Flenaugh, Ralitza Martin, Christopher Parks, Rabih I Bechara
BACKGROUND: Endobronchial ultrasonography has proven to be highly sensitive and specific in the diagnoses of patients with mediastinal and hilar adenopathy. Many of these patients are on a combination of clopidogrel (a compound that inhibits adenosine diphosphate-induced platelet aggregation) and aspirin due to neurological and/or cardiac-related comorbidities, and stopping anticoagulation may place these patients at high risk for potential complications. Our group has previously showed that thoracentesis with an 8-french catheter is safe in patients receiving clopidogrel and aspirin with low risk of complications...
April 16, 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29656758/feasibility-of-endobronchial-ultrasound-transbronchial-needle-aspiration-for-massively-parallel-next-generation-sequencing-in-thoracic-cancer-patients
#5
Simon R Turner, Darren Buonocore, Patrice Desmeules, Natasha Rekhtman, Snjezana Dogan, Oscar Lin, Maria E Arcila, David R Jones, James Huang
INTRODUCTION: Next-generation sequencing (NGS) allows for the identification of a growing number of therapeutic and prognostic molecular targets. However, NGS typically requires greater quantities of DNA than traditional molecular testing does. Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure used to sample central thoracic lesions, but it is not well established whether this technique provides sufficient material for NGS. METHODS: We performed a retrospective review of EBUS-TBNA at our institution (3/1/14-9/28/16)...
May 2018: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29627400/unusual-diagnoses-made-by-convex-probe-endobronchial-ultrasound-guided-transbronchial-needle-aspiration
#6
S Fernandez-Bussy, H Inaty, I Caviedes, G Labarca, M R Vial, A Majid
Endobronchial ultrasound-guided transbronchial needle biopsy (EBUS-TBNA) has proven to be an effective and minimally invasive tool to diagnose and stage lung cancer. However, its use for the diagnosis of rare mediastinal and lung pathologies has been rarely described. Hereby we describe a retrospective chart review of our EBUS-TBNA database for unusual diagnosis made between July 2012 and October 2016. Those conditions considered unusual for EBUS-TBNA diagnosis were identified and their medical records reviewed...
April 4, 2018: Pulmonology
https://www.readbyqxmd.com/read/29607613/prognosis-of-multi-level-n2-positive-non-small-cell-lung-cancer-according-to-lymph-node-staging-using-endobronchial-ultrasound-transbronchial-biopsy
#7
Hee-Young Yoon, Jae Cheol Lee, Sang-We Kim, Hyeong Ryul Kim, Yong-Hee Kim, Se Hoon Choi, Su San Kim, Si Yeol Song, Eun Kyung Choi, Se Jin Jang, Chang-Min Choi
BACKGROUND: The optimal treatment for stage IIIA-N2 non-small cell lung cancer (NSCLC) remains controversial, and multidisciplinary team approaches are needed. Downstaging after induction therapy is a good prognostic factor in surgical patients; however, re-evaluation of nodal status before surgery is challenging. The aim of this study was to evaluate the prognosis of patients with multi-level N2 NSCLC who received surgery or chemoradiation therapy (CRT) according to restaging using endobronchial ultrasound-transbronchial aspiration (EBUS-TBNA)...
April 2, 2018: Thoracic Cancer
https://www.readbyqxmd.com/read/29601559/-advances-in-endoscopic-diagnosis-of-sarcoidosis
#8
REVIEW
Anna Filarecka, Maciej Gnass, Anna Obrochta, Sylwia Szlubowska, Piotr Kocoń, Damian Czyżewski, Juliusz Pankowski, Artur Szlubowski
A diagnosis of pulmonary sarcoidosis is based on the assessment of clinical outcome, radiology findings and detection of noncaseating granulomas in cytology or histology specimens. Cytological material obtained from enlarged lymph nodes and/or histological specimens from bronchial mucosa and lung tissue are examined according to sarcoidosis stage. The most available are standard bronchoscopic methods as conventional transbronchial needle aspiration (cTBNA), endobronchial biopsy (EBB) and transbronchial lung biopsy (TBLB) both performed with use of forceps...
March 27, 2018: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29600073/microrna-expression-profile-in-primary-lung-cancer-cells-lines-obtained-by-endobronchial-ultrasound-transbronchial-needle-aspiration
#9
Juliana Guarize, Fabrizio Bianchi, Elena Marino, Elena Belloni, Manuela Vecchi, Stefano Donghi, Giorgio Lo Iacono, Chiara Casadio, Roberto Cuttano, Massimo Barberis, Pier Paolo Di Fiore, Francesco Petrella, Lorenzo Spaggiari
Background: Novel cancer biomarkers like microRNA (miRNA) are promising tools to gain a better understanding of lung cancer pathology and yield important information to guide therapy. In recent years, new less invasive methods for the diagnosis and staging of NSCLC have become key tools in thoracic oncology and the worldwide spread of endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA). However, appropriate specimen handling is mandatory to achieve adequate results and reproducibility...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29581791/usefulness-of-bronchoscopic-rebiopsy-of-non-small-cell-lung-cancer-with-acquired-resistance-to-epidermal-growth-factor-receptor-tyrosine-kinase-inhibitor
#10
Eun Kyong Goag, Jung Mo Lee, Kyung Soo Chung, Song Yee Kim, Ah Young Leem, Joo Han Song, Ji Ye Jung, Moo Suk Park, Yoon Soo Chang, Young Sam Kim, Joon Chang, Eun Young Kim
Background : Approximately 50% of non-small cell lung cancer (NSCLC) patients with acquired resistance to EGFR-TKI harbor the EGFR mutation T790M. The recent development and wide use of third-generation EGFR-TKIs targeting T790M-mutant NSCLCs have increased the importance of rebiopsy after EGFR-TKI failure. We aimed to investigate the advantages of flexible bronchoscopy as a rebiopsy method and the prevalence of and factors affecting the T790M mutation after EGFR-TKI failure. Methods : We investigated 139 patients who had undergone bronchoscopic rebiopsy and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) between Sep 2014 and Jul 2016...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29575423/cytological-preparations-for-molecular-analysis-a-review-of-technical-procedures-advantages-and-limitations-for-referring-samples-for-testing
#11
REVIEW
G da Cunha Santos, M A Saieg, G Troncone, P Zeppa
Minimally invasive procedures such as endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) must yield not only good quality and quantity of material for morphological assessment, but also an adequate sample for analysis of molecular markers to guide patients to appropriate targeted therapies. In this context, cytopathologists worldwide should be familiar with minimum requirements for refereeing cytological samples for testing. The present manuscript is a review with comprehensive description of the content of the workshop entitled Cytological preparations for molecular analysis: pre-analytical issues for EBUS TBNA, presented at the 40th European Congress of Cytopathology in Liverpool, UK...
April 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29561405/reply-diagnostic-yield-of-ebus-tbna-during-the-learning-curve
#12
Leonello Fuso, Francesco Varone, Daniele Magnini
No abstract text is available yet for this article.
April 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29561404/diagnostic-yield-of-ebus-tbna-during-the-learning-curve
#13
Lars Konge, Paul F Clementsen, Jouke T Annema
No abstract text is available yet for this article.
April 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29561402/needle-tip-fracture-an-unusual-ebus-tbna-complication
#14
Amir Hanna, Adrian Crutu, Pierre Baldeyrou
No abstract text is available yet for this article.
April 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29552519/endobronchial-ultrasound-guided-transbronchial-needle-aspiration-for-staging-of-non-small-cell-lung-cancer
#15
Habiba Hashimi, David T Cooke, Elizabeth A David, Lisa M Brown
Accurate staging for non-small cell lung cancer (NSCLC) is essential to guide therapy. While computed tomography (CT) and positron emission tomography (PET) scan can indicate whether mediastinal lymphadenopathy is present, histologic confirmation is required to complete the staging evaluation. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive technique associated with similar diagnostic yield and improved postoperative pain and complication rates compared to mediastinoscopy...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29543549/role-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-in-the-diagnosis-of-intraocular-inflammation-in-india-our-experience
#16
Bhagya Sudheer, Manisha Agarwal, Deepa Sharma, Ravi Mehta, Kalpana Babu
PURPOSE: To report our experience of using Endobronchial ultrasound-guided transbronchial lymph node aspiration (EBUS-TBNA) in assessing the etiology in uveitis from two tertiary eye-care centers in India. MATERIALS & METHODS: Retrospective interventional case series. RESULTS: A total of 99 patients of uveitis who underwent EBUS-TBNA were included in the study. Mycobacterium tuberculosis (MTb) was detected on culture in 5 cases, 3 cases by polymerase chain reaction and caseating granulomas in 25 cases...
March 15, 2018: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29524065/sclerosing-pneumocytoma-diagnosed-by-preoperative-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-ebus-tbna
#17
Yuki Shiina, Yuichi Sakairi, Hironobu Wada, Hajime Tamura, Taiki Fujiwara, Takahiro Nakajima, Hidemi Suzuki, Masako Chiyo, Masayuki Ota, Satoshi Ota, Yukio Nakatani, Ichiro Yoshino
BACKGROUND: Sclerosing pneumocytoma is a rare lung tumor that is usually recognized as a solitary nodule in the lung. Surgical removal is recommended; however, its clinical diagnosis is still an issue because it is difficult to differentiate from lung adenocarcinomas using a tiny sample obtained from biopsy. CASE PRESENTATION: We report a case of pulmonary sclerosing pneumocytoma located in the upper lobe of the right lung of a 34-year-old woman, which was diagnosed before surgery by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)...
March 9, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29487243/a-survey-of-flexible-bronchoscopy-practices-in-india-the-indian-bronchoscopy-survey-2017
#18
Karan Madan, Anant Mohan, Ritesh Agarwal, Vijay Hadda, Gopi C Khilnani, Randeep Guleria
Background: There is a lack of contemporaneous data on the practices of flexible bronchoscopy in India. Aim: The aim of the study was to study the prevalent practices of flexible bronchoscopy across India. Methods: The "Indian Bronchoscopy Survey" was a 98-question, online survey structured into the following sections: general information, patient preparation and monitoring, sedation and topical anesthesia, procedural/technical aspects, and bronchoscope disinfection/staff protection...
March 2018: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/29476608/clinical-performance-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-for-assessing-programmed-death-ligand-1-expression-in-nonsmall-cell-lung-cancer
#19
Abhishek Biswas, Marino E Leon, Peter Drew, Sebastian Fernandez-Bussy, Larissa V Furtado, Michael A Jantz, Hiren J Mehta
BACKGROUND: Pembrolizumab was recently approved as a first line agent for metastatic NSCLC in patients with high programmed death-ligand 1 (PD-L1) expression. OBJECTIVES: Since a significant portion of lung cancer is diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS TBNA); there is a need for PD-L1 testing in these specimens. However, to date few studies have evaluated performance of cytology specimens from EBUS TBNA for PD-L1 analysis...
February 24, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29476168/semi-quantitative-analysis-of-ebus-elastography-as-a-feasible-approach-in-diagnosing-mediastinal-and-hilar-lymph-nodes-of-lung-cancer-patients
#20
Honghai Ma, Zhou An, Pinghui Xia, Jinlin Cao, Qiqi Gao, Guoping Ren, Xing Xue, Xianhua Wang, Zhehao He, Jian Hu
This study aimed to semi-quantitatively evaluate the elastographic imaging color distribution of mediastinal and hilar lymph nodes (LNs), and explored its utility in helping define malignant and benign LNs for lung cancer patients. We prospectively collected patients who underwent preoperative mediastinal staging of suspected lung cancer by EBUS-TBNA. We analyzed the elastography color distribution of each LN and calculated the blue color proportion (BCP). The LN elastographic patterns were compared with the final EBUS-TBNA pathological results...
February 23, 2018: Scientific Reports
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