Letícia Trindade Almeida, Ariane Coelho Ferraz, Camila Carla da Silva Caetano, Marília Bueno da Silva Menegatto, Ana Cláudia Dos Santos Pereira Andrade, Rafaela Lameira Souza Lima, Fernanda Caetano Camini, Samille Henriques Pereira, Karla Yanca da Silva Pereira, Breno de Mello Silva, Luiza Oliveira Perucci, André Talvani, José Carlos de Magalhães, Cintia Lopes de Brito Magalhães
The first outbreak of Zika virus (ZIKV) infection in the Americas, especially in Brazil, was reported in 2015. Fever, headache, rash, and conjunctivitis are the common symptoms of ZIKV infection. Unexpected clinical outcomes, such as microcephaly and Guillain-Barré syndrome, have also been reported. The recent spread of ZIKV and its association with severe illness has created an urgent need to understand its pathogenesis and find potential therapeutic targets. Studies show that some viruses, including Flavivirus, trigger oxidative stress, which affects cellular metabolism, viral cycle, and pathogenesis...
July 2, 2020: Virus Research