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Constipation in adolescents

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https://www.readbyqxmd.com/read/29774225/polypectomy-for-recurrent-inflammatory-cap-polyposis-combined-with-argon-plasma-coagulation
#1
Soros Anuchapreeda, Patduangpuk Phengsuthi, Prapimphan Aumpansub, Naruemon Wisedopas, Thawee Ratanachuek
A 15-year-old adolescent boy presented with chronic constipation, difficulty in defecation, and episodic bloody stools. A rectal mass lesion was digitally palpated. Colonoscopy showed a large circumferential polypoid lesion of the mid-rectum. Snare polypectomy was performed, and histopathology confirmed a diagnosis of benign inflammatory cap polyposis. At 3-month follow-up, sigmoidoscopy showed multiple recurrences of polyps at the site of the previous rectal polypectomy, which were removed by combined hot snare polypectomy and argon plasma coagulation...
2018: ACG Case Reports Journal
https://www.readbyqxmd.com/read/29762380/clinical-characteristics-of-disaccharidase-deficiencies-among-children-undergoing-upper-endoscopy
#2
Stanley A Cohen, Hannah Oloyede, Benjamin D Gold, Aminu Mohammed, Heather E Elser
OBJECTIVES: The epidemiology and clinical significance of disaccharidase deficiencies have not been thoroughly characterized. Recent work suggests at least genetic sucrase-isomaltase deficiency is more prevalent than previously believed. Because lactase deficiency (LD) is well described, the present study focuses on the clinical characteristics of children with disaccharidase deficiencies determined by esophagogastroduodenoscopy. METHODS: Endoscopic records were reviewed from patients undergoing esophagogastroduodenoscopies with biopsies assayed for disaccharidase activity performed by 13 pediatric gastroenterologists during 5 years (2010-2014)...
June 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29696750/angelman-syndrome-in-adolescence-and-adulthood-a-retrospective-chart-review-of-53-cases
#3
Ankita Prasad, Olivia Grocott, Kimberly Parkin, Anna Larson, Ronald L Thibert
Angelman syndrome is a neurogenetic disorder with varying clinical presentations and symptoms as the individual ages. The goal of this study was to characterize changes over time in the natural history of this syndrome in a large population. We reviewed the medical records of the 53 patients who were born prior to 2000 and seen at the Angelman Syndrome Clinic at Massachusetts General Hospital to assess neurological, sleep, behavioral, gastrointestinal, orthopedic, and ophthalmologic functioning. The average age of this cohort was 24 years...
April 25, 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29681693/anorectal-malformations-in-adolescent-females-a-retrospective-study
#4
Jiledar Rawat, Sudhir Singh, Nitin Pant
Context: While most of the females with anorectal malformations (ARMs) present in either neonatal period or early infancy, a small percentage presents in their adolescence. Aim: The aim is to study the causes of delay in presentation, management, and postoperative outcome in these cases. Settings and Design: This is a retrospective observational study conducted in the Department of Paediatric Surgery, King George's Medical University, Lucknow...
April 2018: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/29681085/two-novel-cases-expanding-the-phenotype-of-setd2-related-overgrowth-syndrome
#5
Maartje C van Rij, Iris H I M Hollink, Paulien Anna Terhal, Sarina G Kant, Claudia Ruivenkamp, Arie van Haeringen, J Anneke Kievit, Martine J van Belzen
The SETD2-related overgrowth syndrome is also called "Luscan-Lumish syndrome" (OMIM 616831) with the clinical characteristics of intellectual disability, speech delay, macrocephaly, facial dysmorphism, and autism spectrum disorders. We report on two novel patients a 4.5-year-old boy and a 23-year-old female adolescent with a speech and language developmental delay, autism spectrum disorder and macrocephaly, who were both diagnosed with SETD2-related overgrowth syndrome due to de novo frameshift mutations in the SETD2 gene...
May 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29555249/factors-associated-with-urinary-incontinence-in-pregnant-adolescents-a-case-control-study
#6
L Barbosa, D Kühni, D Vasconcelos, E Sales, G Lima, M Santos, A Lemos
STUDY OBJECTIVE: to evaluate the factors associated with urinary incontinence (UI) in pregnant adolescents. DESIGN, SETTING, PARTICIPANTS, INTERVENTIONS AND MAIN OUTCOME MEASURES: a case-control study was conducted in three Brazilian public hospitals. Adolescents between the ages of 10 and 19 with gestational age of 27 weeks or more were included. The sample size was calculated using the Open-epi 3.01 program considering gestational obesity as an associated factor. The resulting sample consisted of 658 volunteers, 329 in the case group (with UI) and 329 in the control group (without UI)...
March 16, 2018: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29543374/long-term-outcome-and-quality-of-life-in-patients-with-total-colonic-aganglionosis-in-the-netherlands
#7
D Roorda, M J Witvliet, L M Wellens, D V Schulten, C E J Sloots, I de Blaauw, P M A Broens, J Oosterlaan, L W E van Heurn, A F W van der Steeg
AIM: Total colonic aganglionosis (TCA) is a severe form of Hirschsprung's Disease (HD) associated with a high morbidity. This study assesses long-term functional outcome and Quality of Life (QoL) of TCA patients in a national consecutive cohort. METHODS: Medical records of all patients (n=53) diagnosed between 1995 and 2015 were reviewed on surgical and demographic characteristics. Functional outcome of all non-syndromal patients, aged ≥ four years (n=35) was assessed in medical records and with a questionnaire...
March 15, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29474804/use-of-fibers-in-childhood-constipation-treatment-systematic-review-with-meta-analysis
#8
REVIEW
Patricia Piccoli de Mello, Diego Andre Eifer, Elza Daniel de Mello
OBJECTIVE: To gather current evidence on the use of fiber for constipation treatment in pediatric patients. SOURCE OF DATA: Systematic review with meta-analysis of studies identified through Pubmed, Embase, LILACS and Cochrane databases published up to 2016. INCLUSION CRITERIA: Randomized controlled trials; patients aged between 1 and 18 years and diagnosed with functional constipation receiving or not drug treatment for constipation; articles published in Portuguese, English, Spanish, French, and German in journals accessible to the researchers...
February 21, 2018: Jornal de Pediatria
https://www.readbyqxmd.com/read/29398057/prevalence-of-pediatric-functional-gastrointestinal-disorders-utilizing-the-rome-iv-criteria
#9
Samantha G Robin, Catherine Keller, Russell Zwiener, Paul E Hyman, Samuel Nurko, Miguel Saps, Carlo Di Lorenzo, Robert J Shulman, Jeffrey S Hyams, Olafur Palsson, Miranda A L van Tilburg
OBJECTIVE: To assess the prevalence of functional gastrointestinal (GI) disorders in children 0-18 years old according to the newly established Rome IV diagnostic criteria as reported by parents in a representative community sample. STUDY DESIGN: A cross-sectional study in which mothers (n = 1255) of children aged 0-18 years old in the US were recruited to complete an online survey about their child's GI symptoms, quality of life (QoL), and other health conditions...
April 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29377376/cost-effectiveness-of-intravenous-acetaminophen-and-ketorolac-in-adolescents-undergoing-idiopathic-scoliosis-surgery
#10
Vidya Chidambaran, Rajeev Subramanyam, Lili Ding, Senthilkumar Sadhasivam, Kristie Geisler, Bobbie Stubbeman, Peter Sturm, Viral Jain, Mark H Eckman
BACKGROUND: Enhanced recovery after surgery protocols increasingly use multimodal analgesia after major surgeries with intravenous acetaminophen and ketorolac, despite no documented cost-effectiveness of these strategies. AIMS: The goal of this prospective cohort study was to model cost-effectiveness of adding acetaminophen or acetaminophen + ketorolac to opioids for postoperative outcomes in children having scoliosis surgery. METHODS: Of 106 postsurgical children, 36 received only opioids, 26 received intravenous acetaminophen, and 44 received acetaminophen + ketorolac as analgesia adjuncts...
March 2018: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29368878/risk-factors-for-urinary-tract-infection-in-children-with-urinary-urgency
#11
Rhaiana Gondim, Roberta Azevedo, Ana Aparecida Nascimento Martinelli Braga, Maria Luiza Veiga, Ubirajara Barroso
PURPOSE: To identify which independent variable would be strong predictor of febrile urinary tract infection (UTI) in children and adolescents with overactive bladder. MATERIALS AND METHODS: A search was made of the institute's database for all patients diagnosed with overactive bladder over the preceding four years. Children and adolescents under 18 years of age with overactive bladder and no neurological or anatomical alterations of the lower urinary tract were included in the study...
January 26, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29273891/pedsql-neurofibromatosis-type-1-module-for-children-adolescents-and-young-adults-feasibility-reliability-and-validity
#12
Kavitha Nutakki, James W Varni, Nancy L Swigonski
The objective of the present study was to report on the measurement properties of the Pediatric Quality of Life Inventory (PedsQL) Neurofibromatosis Type 1 Module for pediatric patients ages 5-25 from the perspectives of patients and parents. The 104-item PedsQL NF1 Module and 23-item PedsQL Generic Core Scales were completed in a multi-site national study by 323 patients and 335 parents (343 families). Patients were diagnosed with NF1 using the National Institutes of Health diagnostic criteria. In addition to a Total Scale Score, 18 unidimensional scales were derived measuring skin itch bother, skin sensations, pain, pain impact, pain management, cognitive functioning, speech, fine motor, balance, vision, perceived physical appearance, communication, worry, treatment anxiety, medicines, stomach discomfort, constipation, and diarrhea...
April 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29260510/interventions-for-managing-taste-disturbances
#13
REVIEW
Sumanth Kumbargere Nagraj, Renjith P George, Naresh Shetty, David Levenson, Debra M Ferraiolo, Ashish Shrestha
BACKGROUND: The sense of taste is very much essential to the overall health of an individual. It is a necessary component to enjoy one's food, which in turn provides nutrition to an individual. Any disturbance in taste perception can hamper quality of life in such patients by influencing their appetite, body weight and psychological well-being. Taste disorders have been treated using different modalities of treatment and there is no consensus for the best intervention. Hence this Cochrane Review was undertaken...
December 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29240009/gastrointestinal-symptoms-in-children-and-adolescents-with-neurofibromatosis-type-1
#14
Cecilie Ejerskov, Klaus Krogh, John R Ostergaard, Iben Joensson, Annette Haagerup
OBJECTIVES: Neurofibromatosis type 1 (NF1) is a complex genetic disorder characterized by symptoms of the skin and nervous system. A previous study indicated that constipation is common in children with NF1. The aim of the present study was to investigate the phenotype and prevalence of gastrointestinal symptoms in a population of 4-17-year-olds with NF1 compared to their unaffected siblings. METHODS: Gastrointestinal symptoms were assessed with a web-based, parent or self-administered, validated, Rome® III diagnostic questionnaire...
December 12, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29233454/does-radiotherapy-prior-to-surgery-improve-long-term-prognosis-in-pediatric-colorectal-cancer-in-lower-and-upper-middle-income-countries-with-limited-resources-our-experience-and-literature-review
#15
Yacoob Omar Carrim, Luvo Gaxa, Francisca van der Schyff, Nndweleni Meshack Bida, Fareed Omar, Zarina Lockhat
Colorectal carcinoma in children and adolescents is extremely rare, with an annual incidence <0.3 cases per million, most frequently reported in the second decade of life. It accounts for severe morbidity and poor prognosis owing to the low index of suspicion, delayed diagnosis, advanced stage at presentation and the aggressive tumor nature. Patients present with abdominal pain, vomiting, constipation, abdominal distension, rectal tenesmus, iron-deficiency anemia, change in bowel habit and weight loss...
December 2017: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/29129667/prevalence-of-functional-gastrointestinal-disorders-in-children-and-adolescents-in-the-mediterranean-region-of-europe
#16
Elena Scarpato, Sanja Kolacek, Danijela Jojkic-Pavkov, Vlatka Konjik, Nataša Živković, Enriqueta Roman, Aco Kostovski, Nikolina Zdraveska, Eyad Altamimi, Alexandra Papadopoulou, Thomai Karagiozoglou-Lampoudi, Raanan Shamir, Michal Rozenfeld Bar Lev, Aziz Koleilat, Sirin Mneimneh, Dario Bruzzese, Rosaura Leis, Annamaria Staiano
BACKGROUND & AIMS: Little is known about the prevalence of functional gastrointestinal disorders (FGIDs) in children from the Mediterranean area of Europe. We aimed to assess the prevalence of FGIDs in children and adolescents in this region. METHODS: We collected data on 13,750 children (4-18 years old) enrolled in the Mediterranean-European Area Project, a school-based health study performed in Croatia, Greece, Israel, Italy, Jordan, Lebanon, Macedonia, Serbia, and Spain...
November 9, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29125526/bowel-management-and-continence-in-adults-with-spina-bifida-results-from-the-national-spina-bifida-patient-registry-2009-15
#17
John S Wiener, Kristina D Suson, Jonathan Castillo, Jonathan C Routh, Stacy Tanaka, Tiebin Liu, Elisabeth Ward, Judy Thibadeau, David Joseph, National Spina Bifida Patient Registry
INTRODUCTION: Advances in care have allowed most children with spina bifida (SB) to live to adulthood. The majority have neuropathic bowel dysfunction (NBD), resulting in constipation, incontinence, and diminished quality of life. We sought to 1) describe contemporary NBD management and continence outcomes of adults with SB; 2) describe differences from younger patients; and 3) assess for association with socio-economic factors. METHODS: We analyzed data on NBD management and continence from the National Spina Bifida Patient Registry (NSBPR)...
December 11, 2017: Journal of Pediatric Rehabilitation Medicine
https://www.readbyqxmd.com/read/29110829/hirschsprung-disease-bowel-function-beyond-childhood
#18
Tomas Wester, Anna Löf Granström
Hirschsprung disease is a developmental defect of the enteric nervous system characterized by lack of enteric neurons in the distal hindgut. There are numerous reports on short-term outcomes indicating that impaired bowel function is common. Recently, several controlled studies show that bowel function outcomes are affected beyond childhood, in adolescents and adults, compared with healthy control subjects. Constipation and fecal incontinence are common. The impaired bowel function appears to have a negative impact on quality of life, although, a majority of patients have adapted to their symptoms...
October 2017: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/28975729/brain-processing-of-rectal-sensation-in-adolescents-with-functional-defecation-disorders-and-healthy-controls
#19
S M Mugie, I J N Koppen, M M van den Berg, P F C Groot, L Reneman, M B de Ruiter, M A Benninga
BACKGROUND: Decreased sensation of urge to defecate is often reported by children with functional constipation (FC) and functional nonretentive fecal incontinence (FNRFI). The aim of this cross-sectional study was to evaluate cerebral activity in response to rectal distension in adolescents with FC and FNRFI compared with healthy controls (HCs). METHODS: We included 15 adolescents with FC, 10 adolescents with FNRFI, and 15 young adult HCs. Rectal barostat was performed prior to functional magnetic resonance imaging (fMRI) to determine individual pressure thresholds for urge sensation...
March 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28974365/predictors-of-outcome-in-children-and-adolescents-with-overactive-bladder-treated-with-parasacral-transcutaneous-electrical-nerve-stimulation
#20
Anselmo Hoffmann, Clara Sampaio, Ana Aparecida Nascimento, Maria Luiza Veiga, Ubirajara Barroso
BACKGROUND: Parasacral transcutaneous electrical nerve stimulation (TENS) has emerged as an effective treatment for overactive bladder (OAB) in view of its high success rates in improving lower urinary tract symptoms and constipation, with no direct side effects. However, the clinical characteristics associated with the outcomes remain to be established. OBJECTIVE: The aim of this study was to evaluate potential predictors of outcome in children with OAB treated using parasacral TENS...
September 8, 2017: Journal of Pediatric Urology
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