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Vikram Kilambi, Sanjay Mehrotra
BACKGROUND: Geographic disparities persist in access to liver transplantation. Candidates with similar urgency experience varying opportunities for transplants across the US. Policymakers are poised to act and 1 proposal entails reorganizing the current OPTN of 11 regions into 8 districts. However, redistricting has the shortcomings that OPOs are disconnected from their immediate neighbors by district borders and that it is not easily responsive to uncertainty resulting from variability in donor and listing rates...
October 7, 2016: Transplantation
(no author information available yet)
This final rule with comment period revises the Medicare hospital outpatient prospective payment system (OPPS) and the Medicare ambulatory surgical center (ASC) payment system for CY 2017 to implement applicable statutory requirements and changes arising from our continuing experience with these systems. In this final rule with comment period, we describe the changes to the amounts and factors used to determine the payment rates for Medicare services paid under the OPPS and those paid under the ASC payment system...
November 14, 2016: Federal Register
Zheming Li, Joakim Rosell, Marcus Aldén, Mattias Richter
Spatially and temporally resolved measurements are of great importance in turbulent premixed flame studies, especially when investigating rapid processes such as when flame local extinction, re-ignition, or flashback occur in a reacting flow. Here, an experimental approach for simultaneously probing two different species at high frame rates (50 kHz) is presented by employing a multi-YAG laser system. The laser radiation at 355 nm generated by a multi-YAG laser system was split into two beam paths: one beam for exciting formaldehyde and the other for pumping an optical parametric oscillator (OPO)...
November 18, 2016: Applied Spectroscopy
Yanmin Duan, Haiyong Zhu, Changwen Xu, Xiukai Ruan, Guihua Cui, Yaoju Zhang, Dingyuan Tang, Dianyuan Fan
We reported a compact self-cascaded KTA-OPO source for 2.6 μm coherent light generation. The OPO is driven in a diode end-pumped and Q-switched Nd:YVO<sub>4</sub> laser cavity. Two OPO processes occurred in the same KTA crystal with non-critical phase matching. At an incident diode pump power of 8.7 W and a pulse repetition frequency of 60 kHz, the OPO can generate a maximum average output power of 445 mW at 2.59 μm. The slope efficiency was about 12.7%, and the power fluctuation was less than 8%...
November 14, 2016: Optics Express
Natsuko Watanabe, Toshiharu Nagai, Hoyo Mizobe, Kazuaki Yoshinaga, Akihiko Yoshida, Yohei Kitamura, Takashi Shimizu, Fumiaki Beppu, Naohiro Gotoh
The absolute amount of triacylglycerol (TAG) positional isomers was analyzed in rat milk fat, a representative of non-ruminant milk fat, using a HPLC-UV-atmospheric pressure chemical ionization-MS/MS system equipped with an octacosyl silylation column or polymeric ODS column. TAGs consisting of two oleic acids (O) and one palmitic acid (P) were the most abundant. In particular, β-OPO, a TAG binding P at the β-position (sn-2) and two Os at the α-positions (sn-1/3), was prominent. The β-OPO content decreased over time, while a TAG consisting of two Ps and one capric acid, a medium-chain fatty acid, increased...
December 1, 2016: Journal of Oleo Science
Jialin Mei, Kai Zhong, Maorong Wang, Yang Liu, Degang Xu, Wei Shi, Yuye Wang, Jianquan Yao, Robert A Norwood, Nasser Peyghambarian
A compact efficient high-repetition-rate doubly-resonant dual-wavelength KTP optical parametric oscillator (OPO), with output power up to 3.65 W and tuning ranges of 2.088-2.133 μm/2.171-2.122 μm for signal/idler waves, was deployed for terahertz (THz) generation in a GaSe crystal. Based on difference frequency generation (DFG), the THz wave was continuously tunable from 730.9 μm (0.41 THz) to 80.8 μm (3.71 THz), believed to be the first report of a compact high-repetition-rate widely-tunable THz source...
October 3, 2016: Optics Express
Antoni Margalida, Juan Manuel Pérez-García, Ivan Afonso, Rubén Moreno-Opo
Understanding the movement of threatened species is important if we are to optimize management and conservation actions. Here, we describe the age and sex specific spatial and temporal ranging patterns of 19 bearded vultures Gypaetus barbatus tracked with GPS technology. Our findings suggest that spatial asymmetries are a consequence of breeding status and age-classes. Territorial individuals exploited home ranges of about 50 km(2), while non-territorial birds used areas of around 10 000 km(2) (with no seasonal differences)...
October 25, 2016: Scientific Reports
Darren E Stewart, Victoria C Garcia, John D Rosendale, David K Klassen, Bob J Carrico
BACKGROUND: The proportion of deceased donor kidneys recovered for transplant but discarded increased steadily in the U.S. over 2 decades, from 5.1% in 1988 to 19.2% by 2009. Over 100,000 patients are waiting for a kidney transplant, yet 3,159 kidneys were discarded in 2015. METHODS: We evaluated trends in donor characteristics, discard reasons, and OPO-specific discard rates. Multivariable regression and propensity analysis were used to estimate the proportion of the discard rate rise in the 2000's attributable to changes in donor factors and decisions to biopsy and pump kidneys...
October 19, 2016: Transplantation
L A Siminoff, G P Alolod, M Wilson-Genderson, E Y N Yuen, H M Traino
Available literature points to healthcare providers' discomfort with donation after cardiac death (DCD) and their perception of public reluctance toward the procedure. Using a national sample, we report on the communication content of actual DCD and donation after brain death (DBD) approaches by organ procurement organization (OPO) requesters and compare family decision makers' (FDMs') experiences of both modalities. We recruited 1601 FDMs using a validated protocol; 347 (21.7%) were of potential DCD donors...
October 18, 2016: American Journal of Transplantation
John Lunz, Lisa Hinsdale, Casey King, Robin Pastush, Magnolia Buenvenida, Michael Harmon
Since implementation, the new UNOS OPTN kidney allocation system (KAS) has drastically expanded the pool of available kidneys to candidates that may have previously waited extended periods for an organ offer. This is particularly true for highly sensitized patients. The changes to the KAS have had ramifications throughout the transplant process, including for organ procurement organizations (OPO) and local transplant hospital call centers. Here, we will examine the impact of the new KAS on the organ donation process and highlight the necessary interactions between the OPO and transplant centers to best match donor kidneys and highly sensitized recipients...
October 12, 2016: Human Immunology
R Sarlo, G Pereira, M Surica, D Almeida, C Araújo, O Figueiredo, E Rocha, E Vargas
Establishing an organization to promote organ donation and a good organ procurement team assure quality and improve performance on organ donation rates. Brazil's organ procurement structure is based on 2 models disseminated worldwide: the "Spanish model," based on in-house coordinators, and the "American organ procurement organization (OPO) model," with extra-hospital coordinators. In 2006, Brazil's Federal Government had formally introduced the in-house coordination model for every hospital equipped with a mechanical ventilator bed...
September 2016: Transplantation Proceedings
Lauren B Cooper, Carmelo A Milano, Melissa Williams, Wendy Swafford, Donna Croezen, Adrian B Van Bakel, Joseph G Rogers, Chetan B Patel
BACKGROUND: Acute hypothyroidism after brain death results in hemodynamic impairments that limit availability of donor hearts. Thyroid hormone infusions can halt that process and lead to increased utilization of donor organs, but prolonged use of thyroid replacement has not been well studied. METHODS: We developed a 15-question survey regarding policies, procedures, and reporting of thyroid hormone use by organ procurement organizations (OPOs). The survey was posted for 5 weeks on the Association of OPOs Portal...
December 2016: Clinical Transplantation
Yaping Shang, Jiangming Xu, Peng Wang, Xiao Li, Pu Zhou, Xiaojun Xu
The longterm stability of the laser system is very important in many applications. In this letter, an ultra-stable, broadband, mid-infrared (MIR) optical parametric oscillator (OPO) pumped by a super-fluorescent fiber source is demonstrated. An idler MIR output power of 11.3 W with excellent beam quality was obtained and the corresponding pump-to-idler conversion slope efficiency was 15.9%. Furthermore, during 1h measurement at full power operation, the peak-to-peak fluctuation of idler output power was less than 1...
September 19, 2016: Optics Express
Nurmemet Abdukerim, Lizhu Li, Martin Rochette
We report the first chalcogenide-based optical parametric oscillator (OPO) relying on pure parametric gain. The all-fiber OPO operates in the wavelength range of 2 μm and is tunable over 290 nm from the combined Stokes and anti-Stokes contributions. The gain medium is a 10 cm long chalcogenide microwire made from a high modal confinement As<sub>2</sub>Se<sub>3</sub> core with cyclo olefin polymer cladding, leading to optimized chromatic dispersion, high nonlinearity, and broadband transparency...
September 15, 2016: Optics Letters
Luke Maidment, Peter G Schunemann, Derryck T Reid
We report a femtosecond optical parametric oscillator (OPO) based on the new semiconductor gain material orientation-patterned gallium phosphide (OP-GaP), which enables the production of high-repetition-rate femtosecond pulses spanning 5-12 μm with average powers in the few to tens of milliwatts range. This is the first example of a broadband OPO operating across the molecular fingerprint region, and we demonstrate its potential by conducting broadband Fourier-transform spectroscopy using water vapor and a polystyrene reference standard...
September 15, 2016: Optics Letters
Delphine Descloux, Guillaume Walter, Erwan Cadiou, Jean-Baptiste Dherbecourt, Guillaume Gorju, Jean-Michel Melkonian, Myriam Raybaut, Cyril Drag, Antoine Godard
We report on a widely tunable synchronously pumped picosecond optical parametric oscillator (OPO) combining an aperiodically poled MgO-doped LiNbO<sub>3</sub> crystal as a broadband gain medium and an axially chirped volume Bragg grating as a spectral filtering dispersive element. Translation of the Bragg grating along the beam axis enables wavelength tuning over 215 nm around 3.82 μm and provides spectral narrowing. Rapid continuous tuning over 150 nm in 100 ms is demonstrated.
September 1, 2016: Optics Letters
Manouela V Valtcheva, Bryan A Copits, Steve Davidson, Tayler D Sheahan, Melanie Y Pullen, Jordan G McCall, Krikor Dikranian, Robert W Gereau
Primary cultures of rodent sensory neurons are widely used to investigate the cellular and molecular mechanisms involved in pain, itch, nerve injury and regeneration. However, translation of these preclinical findings may be greatly improved by direct validation in human tissues. We have developed an approach to extract and culture human sensory neurons in collaboration with a local organ procurement organization (OPO). Here we describe the surgical procedure for extraction of human dorsal root ganglia (hDRG) and the necessary modifications to existing culture techniques to prepare viable adult human sensory neurons for functional studies...
October 2016: Nature Protocols
Tonya Smith-Jackson, Rodney Middlebrooks, John Francis, Tiara Gray, Kaleb Nelson, Briana Steele, Kionda Townsend, Cedric Watlington
BACKGROUND: Open plan offices have proliferated for the past several decades with more and more workers being concentrated in office buildings. Several studies have identified a number of negative factors associated with open plan offices, and those include noise, speech interference, lack of privacy, and a perceived loss of control over work. While negative factors have been identified several times in the literature, many studies rely on either surveys or highly controlled environments...
August 12, 2016: Work: a Journal of Prevention, Assessment, and Rehabilitation
Christian Fries, Marco Weitz, Christian Theobald, Patric V Löwis Of Menar, Jürgen Bartschke, Johannes A L'huillier
Increasing data acquisition rates in metrology applications based on optical parametric oscillators (OPOs) can accelerate measurement processes. To achieve this, flash-lamp systems with low pulse repetition frequencies of 10-100 Hz used as a pump source for the OPOs could be replaced by diode-pumped solid-state lasers in the kHz range. We demonstrate a 969 nm pumped Yb:YAG ceramic laser yielding 21.6 W output power, 12.5 mJ pulse energy, and excellent beam quality. Fluorescence feedback control, developed from gain dynamics simulations in two operating regimes, allows stable operation at 6...
August 20, 2016: Applied Optics
Margaret Kathleen Menzel Ellis, Mitchell Brett Sally, Darren Malinoski
INTRODUCTION: Despite continuous advances in transplant medicine, there is a persistent worldwide shortage of organs available for donation. There is a growing body of research that supports that optimal management of deceased organ donors in Intensive Care Unit can substantially increase the availability of organs for transplant and improve outcomes in transplant recipients. METHODS: A systematic literature review was performed, comprising a comprehensive search of the PubMed database for relevant terms, as well as individual assessment of references included in large original investigations, and comprehensive society guidelines...
July 2016: Indian Journal of Urology: IJU: Journal of the Urological Society of India
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