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https://www.readbyqxmd.com/read/28514250/accept-or-decline-an-analytics-based-decision-tool-for-kidney-offer-evaluation
#1
Dimitris Bertsimas, Jerry Kung, Nikolaos Trichakis, David Wojciechowski, Parsia A Vagefi
BACKGROUND: When a deceased-donor kidney is offered to a waitlisted candidate, the decision to accept or decline the organ relies primarily upon a practitioner's experience and intuition. Such decisions must achieve a delicate balance between estimating the immediate benefit of transplantation and the potential for future higher-quality offers. However, the current experience-based paradigm lacks scientific rigor and is subject to the inaccuracies that plague anecdotal decision-making...
May 17, 2017: Transplantation
https://www.readbyqxmd.com/read/28465809/process-and-barriers-to-organ-donation-and-causes-of-brain-death-in-northeast-of-iran
#2
Abdollah Bahrami, Ebrahim Khaleghi, Ali Khorsand Vakilzadeh, Monavar Afzalaghaee
INTRODUCTION: Organ transplantation is the treatment of choice for some diseases. However, the need for cadaveric organ donation has either plateaued or is on a decreasing trend in some countries, especially in developed ones. In this study, we aimed to identify the barriers to organ donation in brain dead patients, who were referred to the organ procurement organizations (OPO) in northeast Iran. METHODS: In this cross-sectional study during 2006 to 2013, data were collected from medical records of brain dead patients...
February 2017: Electronic Physician
https://www.readbyqxmd.com/read/28414351/phase-matching-properties-of-baga-sub-4-sub-se-sub-7-sub-for-shg-and-sfg-in-the-0-901-10-5910%C3%A2-%C3%A2-%C3%AE-m-range
#3
Kiyoshi Kato, Kentaro Miyata, Valentin Petrov
We report new experimental results on the phase-matching properties of a BaGa<sub>4</sub>Se<sub>7</sub> crystal for harmonic generation of a Nd:YAG laser-pumped AgGaS<sub>2</sub> optical parametric oscillator (OPO) and a CO<sub>2</sub> laser in the 0.901-10.5910 μm range. In addition, we present new Sellmeier equations that provide a good reproduction of the present experimental results as well as the published data points for a Nd:YAG laser-pumped OPO and an optical parametric amplifier (OPA) in the 3...
April 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/28397363/improved-time-to-notification-of-impending-brain-death-and-increased-organ-donation-using-an-electronic-clinical-decision-support-system
#4
J L Zier, A B Spaulding, M Finch, T Verschaetse, R Tarrago
Early referral of patients to an organ procurement organization (OPO) may positively impact donation outcomes. We implemented an electronic clinic decision support (CDS) system to automatically notify our OPO of children meeting clinical triggers indicating impending brain death. Medical records of all patients who died in a pediatric critical care unit or were referred for imminent death for three years prior to installation of the initial CDS (pre-CDS) and for one year after implementation of the final CDS (post-CDS) were reviewed...
April 11, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28380765/higher-order-mode-entanglement-in-a-type-ii-optical-parametric-oscillator
#5
Jun Guo, Chunxiao Cai, Long Ma, Kui Liu, Hengxin Sun, Jiangrui Gao
Nonclassical beams in high order spatial modes have attracted much interest but they exhibit much less squeezing and entanglement than the fundamental spatial modes, limiting their applications. We experimentally demonstrate the relation between pump modes and entanglement of first-order Hermite Gauss modes (HG<sub>10</sub> entangled states) in a type II OPO and show that the maximum entanglement of high order spatial modes can be obtained by optimizing the pump spatial mode. To our knowledge, this is the first time to report this...
March 6, 2017: Optics Express
https://www.readbyqxmd.com/read/28380740/frequency-comb-assisted-two-photon-vibrational-spectroscopy
#6
Juho Karhu, Markku Vainio, Markus Metsälä, Lauri Halonen
We report a setup for high-resolution two-photon spectroscopy using a mid-infrared continuous wave optical parametric oscillator (CW-OPO) and a near-infrared diode laser as the excitation sources, both of which are locked to fully stabilized optical frequency combs. The diode laser is directly locked to a commercial near-infrared optical frequency comb using an optical phase-locked loop. The near-infrared frequency comb is also used to synchronously pump a degenerate femtosecond optical parametric oscillator to produce a fully stabilized mid-infrared frequency comb...
March 6, 2017: Optics Express
https://www.readbyqxmd.com/read/28372437/fast-precise-and-widely-tunable-frequency-control-of-an-optical-parametric-oscillator-referenced-to-a-frequency-comb
#7
Alexander Prehn, Rosa Glöckner, Gerhard Rempe, Martin Zeppenfeld
Optical frequency combs (OFCs) provide a convenient reference for the frequency stabilization of continuous-wave lasers. We demonstrate a frequency control method relying on tracking over a wide range and stabilizing the beat note between the laser and the OFC. The approach combines fast frequency ramps on a millisecond timescale in the entire mode-hop free tuning range of the laser and precise stabilization to single frequencies. We apply it to a commercially available optical parametric oscillator (OPO) and demonstrate tuning over more than 60 GHz with a ramping speed up to 3 GHz/ms...
March 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28364665/doppler-limited-high-resolution-spectrum-and-vpt2-assisted-assignment-of-the-c-h-stretch-of-ch2br2
#8
Ibrahim Sadiek, Gernot Friedrichs
The Doppler limited non-saturated rotationally resolved infrared spectra of the symmetric and asymmetric CH-stretch bands of CH2Br2 have been measured. A continuous wave cavity ringdown setup with a widely tunable Mid-IR-OPO laser light source yielded a single-shot minimum absorption of 4.9×10(-8)cm(-1). In contrast to the heavily congested ν1 band, the ν6 band showed partially resolved rotational features that may serve as suitable absorption targets in future environmental detection schemes for CH2Br2...
March 16, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28317752/facile-preparation-of-magnetic-carbon-nanotubes-immobilized-lipase-for-highly-efficient-synthesis-of-1-3-dioleoyl-2-palmitoylglycerol-rich-human-milk-fat-substitutes
#9
Mingming Zheng, Shi Wang, Xia Xiang, Jie Shi, Juan Huang, Qianchun Deng, Fenghong Huang, Junyong Xiao
In this study, Candida lipolytica lipase (CLL) was immobilized on magnetic multi-walled carbon nanotubes (mMWCNTs) via hydrophobic and cation-exchange interaction. The resultant immobilized CLL showed much better thermal stability, biocatalyst activity and easier recycling than the free form. A method for efficient enzymatic acidolysis of tripalmitin (PPP) with oleic acid (OA), to produce OPO-rich TAGs, was developed, using the immobilized CLL as the biocatalyst. Under optimized conditions (2% water, 20mg/ml enzyme, 1:6 PPP/OA, 50°C, 2h), the content of OPO in the final product reached 46...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28262823/multi-gigahertz-femtosecond-airy-beam-optical-parametric-oscillator-pumped-at-78-mhz
#10
A Aadhi, Varun Sharma, N Apurv Chaitanya, G K Samanta
We report a high power ultrafast Airy beam source producing femtosecond pulses at multi-gigahertz (GHz) repetition rate (RR). Based on intra-cavity cubic phase modulation of an optical parametric oscillator (OPO) designed in high harmonic cavity configuration synchronous to a femtosecond Yb-fiber laser operating at 78 MHz, we have produced ultrafast 2D Airy beam at multi-GHz repetition rate through the fractional increment in the cavity length. While small (<1 mm) crystals are used in femtosecond OPOs to take the advantage of broad phase-matching bandwidth, here, we have exploited the extended phase-matching bandwidth of a 50-mm long Magnesium-oxide doped periodically poled LiNbO3 (MgO:PPLN) crystal for efficient generation of ultrafast Airy beam and broadband mid-IR radiation...
March 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28241627/hybrid-q-switched-laser-with-mos-sub-2-sub-saturable-absorber-and-aom-driven-sub-nanosecond-ktp-opo
#11
Junpeng Qiao, Shengzhi Zhao, Kejian Yang, Jia Zhao, Guiqiu Li, Dechun Li, Tao Li, Wenchao Qiao
Two-dimensional (2D) materials, especially transition-metal dichalcogenides, such as molybdenum disulfide (MoS<sub>2</sub>) and tungsten disulfide (WS<sub>2</sub>), have attracted great interests due to their exceptional optical properties as saturable absorbers in laser systems. In this work, at first, we presented a diode-pumped passively Q-switched laser with MoS<sub>2</sub> saturable absorber (MoS<sub>2</sub>-SA). At an incident pump power of 6.54 W, a maximum output power of 1...
February 20, 2017: Optics Express
https://www.readbyqxmd.com/read/28241551/mid-infrared-zgp-opo-with-a-high-optical-to-optical-conversion-efficiency-of-75-7
#12
Li Wang, Tinglun Xing, Shuwu Hu, Xianyou Wu, Haixin Wu, Jiyang Wang, Haihe Jiang
We experimentally demonstrate a ZnGeP<sub>2</sub> based optical parametric oscillator (ZGP-OPO) with a record of the optical-to-optical conversion efficiency. To improve the conversion efficiency, we design and construct a double-pass pumped high-gain OPO and a matched large-sized high-peak-power pump beam to suppress the spatial walk-off and conversion. Pulse energy of 19 mJ with pulse width of 27.8 ns at 5 Hz in the mid-infrared 3-5 μm waveband is obtained in the doubly resonated ZGP-OPO, the beam quality M<sup>2</sup> is about 9...
February 20, 2017: Optics Express
https://www.readbyqxmd.com/read/28207635/kidney-transplantation-rates-across-glomerulonephritis-subtypes-in-the-united-states
#13
Michelle M O'Shaughnessy, Sai Liu, Maria E Montez-Rath, Richard A Lafayette, Wolfgang C Winkelmayer
BACKGROUND: Whether kidney transplantation rates differ by glomerulonephritis (GN) subtype remains largely unknown. METHODS: Using the US Renal Data System, we identified all adult patients with ESRD attributed to 1 of 6 GN subtypes who initiated dialysis in the US (1996-2013). Patients with diabetic nephropathy (DN) and autosomal-dominant polycystic kidney disease (ADPKD) served as "external" non-GN comparators. Using Cox proportional hazards regression, with death considered a competing risk, we estimated hazard ratios [HRs (95% confidence intervals)] for first kidney transplantation, controlling for year, demographics, comorbidities, socioeconomic factors, and Organ Procurement Organization (OPO)...
February 15, 2017: Transplantation
https://www.readbyqxmd.com/read/28168823/opo-strategies-to-prevent-unintended-use-of-kidneys-exported-for-high-pra-98-cpra-recipients
#14
A S Paramesh, N Neidlinger, M Salvatore, A Smith, A Friedman, W Payne, T Taber, C Wright
Since the advent of the Kidney Allocation System (KAS), matched candidates with high (>98%) panel reactive antibody (hPRA) are given priority over local candidates with lower PRA. This often leads to exporting of kidneys. Data for these kidneys are not detailed on routine reports. Twenty-two organ procurement organizations prospectively submitted data from August 2015 to July 2016, describing allocation practices of kidneys to hPRA patients and outcomes of these kidneys. Five hundred twenty out of 6924 procured kidneys were exported for hPRA recipients...
February 6, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28146518/simultaneous-two-color-stimulated-raman-scattering-microscopy-by-adding-a-fiber-amplifier-to-a-2-ps-opo-based-srs-microscope
#15
Wenlong Yang, Ang Li, Yuanzhen Suo, Fa-Ke Lu, X Sunney Xie
Stimulated Raman scattering (SRS) microscopy is a label-free chemical imaging technique. Two-color imaging is often necessary to determine the distribution of chemical species in SRS microscopy. Current multi-color SRS imaging methods involve complicated instrumentation or longer data acquisition time or are limited to transmission imaging. In this Letter, we show that by adding a simple fiber amplifier to a 2 ps laser source and optical-parametric-oscillator-based SRS setup, one can achieve simultaneous two-color or frequency modulation SRS microscopy...
February 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28145483/determination-of-blue-light-induced-infrared-absorption-based-on-mode-matching-efficiency-in-an-optical-parametric-oscillator
#16
Yajun Wang, Wenhai Yang, Zhixiu Li, Yaohui Zheng
Non-classical squeezed states of light at a compatible atomic wavelength have a potential application in quantum information protocols for quantum states delaying or storaging. An optical parametric oscillator (OPO) with periodically poled potassium titanyl phosphate (PPKTP) is the most effective method for generating this squeezed state. However, it is a challege for the nonlinear interaction in PPKTP crystal at the D1 line of rubidium atomic, due to a strong blue-light-induced infrared absorption (BLIIRA)...
February 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28117732/photoacoustic-spectroscopy-for-the-determination-of-lung-cancer-biomarkers-a-preliminary-investigation
#17
Yannick Saalberg, Henry Bruhns, Marcus Wolff
With 1.6 million deaths per year, lung cancer is one of the leading causes of death worldwide. One reason for this high number is the absence of a preventive medical examination method. Many diagnoses occur in a late cancer stage with a low survival rate. An early detection could significantly decrease the mortality. In recent decades, certain substances in human breath have been linked to certain diseases. Different studies show that it is possible to distinguish between lung cancer patients and a healthy control group by analyzing the volatile organic compounds (VOCs) in their breath...
January 21, 2017: Sensors
https://www.readbyqxmd.com/read/28108262/deceased-organ-donor-management-does-hospital-volume-matter
#18
Madhukar S Patel, Jahan Mohebali, Mitchell Sally, Tahnee Groat, Parsia A Vagefi, David C Chang, Darren J Malinoski
BACKGROUND: Identification of strategies to improve organ donor use remains imperative. Despite the association between hospital volume and outcomes for many common disease processes, there have been no studies that assess the impact of organ donor hospital volume on organ yield. STUDY DESIGN: A prospective observational study of all deceased organ donors managed by 10 organ procurement organizations across United Network for Organ Sharing regions 4, 5, and 6 was conducted from February 2012 to June 2015...
March 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28072757/organ-procurement-organization-survey-of-practices-and-beliefs-regarding-prerecovery-percutaneous-liver-biopsy-in-donation-after-neurologic-determination-of-death
#19
Joseph Benton Oliver, Andrea Fleisch Marcus, Mark Paster, Joseph Nespral, Advaith Bongu, George Dikdan, Lloyd Brown, Nikole Neidlinger, Baburao Koneru
BACKGROUND: Prerecovery liver biopsy (PLB) allows histological evaluation of the organ before procurement. The opinions and what factors might influence PLB use within Organ Procurement Organizations (OPOs) are unknown. METHODS: A survey instrument was distributed by the Association of OPOs to the clinical directors of all 58 OPOs. Descriptive statistics were calculated. Results were also stratified based on OPO characteristics. RESULTS: Forty-nine (84...
April 2017: Transplantation
https://www.readbyqxmd.com/read/28059367/harmonically-pumped-femtosecond-optical-parametric-oscillator-with-multi-gigahertz-repetition-rate
#20
Wenlong Tian, Zhaohua Wang, Jiangfeng Zhu, Zhiyi Wei
We report a multi-gigahertz (GHz) repetition-rate femtosecond MgO:PPLN optical parametric oscillator (OPO) harmonically pumped by a 75.6 MHz Kerr-lens mode-locked Yb:KGW laser. By fractionally increasing the OPO cavity length, we obtained OPO operation up to the 493rd harmonic of the pump laser repetition rate, corresponding to a repetition rate as high as 37.3 GHz. Using a 1.5% output coupler, we are able to extract signal pulses with up to 260 mW average power at the 102nd harmonic (7.7 GHz) and 90 mW at the 493rd harmonic (37...
December 26, 2016: Optics Express
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