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Kidney biopsy and bleeding

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https://www.readbyqxmd.com/read/29552340/a-retrospective-analysis-of-the-utility-and-safety-of-kidney-transplant-biopsies-by-nephrology-trainees-and-consultants
#1
Michael E Reschen, Andrea Mazzella, Edward Sharples
Background and aims: Dysfunction of a kidney transplant often requires histological sampling by percutaneous ultrasound-guided core needle biopsy. Transplant biopsy is more specialized than native kidney biopsy, the indications and complications are less well defined and in England are performed mainly by nephrologists. The aims of the study were to evaluate the adequacy and complication rate in living and deceased donor recipients according to training status of the nephrologist, assess the accuracy of physicians in predicting rejection, the threshold creatinine rise for biopsy, and the change in drug management post-biopsy...
April 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29534686/unexpected-presentation-of-allograft-dysfunction-triggered-by-page-kidney-phenomenon-immediately-after-kidney-transplantation-a-case-report
#2
Shunta Hori, Mitsuru Tomizawa, Fumisato Maesaka, Takuya Owari, Yosuke Morizawa, Yasushi Nakai, Makito Miyake, Tatsuo Yoneda, Nobumichi Tanaka, Katsunori Yoshida, Kiyohide Fujimoto
BACKGROUND: Page kidney phenomenon is caused by strong renal parenchymal compression and leads to renal hypoperfusion and microvascular ischemia, resulting in renal dysfunction and hypertension. Although the development of Page kidney phenomenon in allograft is rare, most of its cases are induced by allograft biopsy or trauma. We observed a case of Page kidney phenomenon that was induced by unusual causes immediately after kidney transplantation. CASE PRESENTATION: A 66-year-old man, whose wife donated a kidney, underwent ABO-compatible living kidney transplantation...
March 13, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29531642/one-year-allograft-and-patient-survival-in-renal-transplant-recipients-receiving-antiplatelet-therapy-at-the-time-of-transplantation
#3
T Benkö, M Gottmann, S Radunz, A Bienholz, F H Saner, J W Treckmann, A Paul, D P Hoyer
Background: Antiplatelet therapy is common in patients on the waiting list for kidney transplantation. Objective: To evaluate the incidence of post-operative bleeding in patients with antiplatelet therapy undergoing kidney transplantation and analyze the impact on the outcome. Methods: We studied all patients with concomitant antiplatelet therapy undergoing kidney transplantation in our center from January 2007 to June 2012. Data were collected by chart review...
2018: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/29492991/tacrolimus-interaction-with-oral-oestrogen-in-kidney-transplant-recipients-a-case-control-study
#4
M Ghadimi, S Dashti-Khavidaki, M Shahali, M Gohari, M-R Khatami, A Alamdari
WHAT IS KNOWN AND OBJECTIVE: Oestrogens could inhibit the metabolism of drugs, such as calcineurin inhibitors, that are substrates for cytochrome P-450 microsomal enzymes. This study assessed the potential tacrolimus interaction with oral conjugated oestrogen in kidney transplant recipients who received conjugated oestrogen as prophylaxis against bleeding, before kidney biopsy. METHODS: In this case-control study, 13 kidney transplant recipients who received oral conjugated oestrogen as prophylaxis against uraemic bleeding before allograft biopsy were considered as cases...
February 28, 2018: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29380515/acute-hemodialysis-in-a-young-man-with-severe-symptomatic-hyponatremia-and-kidney-injury
#5
Catherine Courteau, Alex Al Khoury, Rene P Michel, Catherine L Weber
A 35-year-old man presented with severe hypo-osmolar hyponatremia (serum sodium 99 mmol/L), profound nonoliguric renal failure (serum creatinine 1240 μmol/L), and nephrotic range proteinuria. Computed tomography of the abdomen revealed nephromegaly and no obstruction. The patient was admitted to the intensive care unit (ICU) and conventional hemodialysis was initiated. To avoid rapid sodium correction, we prescribed concurrent dialysate flow, a low dialysate sodium concentration, a small surface area dialyzer, and a low blood flow rate...
January 30, 2018: Hemodialysis International
https://www.readbyqxmd.com/read/29340149/acute-kidney-injury-due-to-multiple-hymenoptera-stings-a-clinicopathological-study
#6
Sanjay Vikrant, Anupam Parashar
Background: Acute kidney injury (AKI) after multiple Hymenoptera stings is well known but still a rare phenomenon. Methods: We conducted a retrospective study of the clinicopathological spectrum of AKI due to multiple Hymenoptera stings over 13 years (July 2003-June 2016). Results: A total of 35 patients were diagnosed with AKI due to multiple Hymenoptera stings. The mean age of the patients was 44.7 ± 17.4 years and the majority (60%) were men...
August 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29301131/safety-of-outpatient-kidney-biopsies
#7
Bojana Šimunov, Mihaela Gunjača, Branislav Čingel, Dinko Škegro, Mladen Knotek
BACKGROUND: Kidney biopsy is frequently performed in our centre as an outpatient procedure. The aim of this study was to evaluate the safety of biopsy in the outpatient setting. METHODS: We analysed kidney biopsies performed from March 2013 to February 2017. Seven hundred twenty-five biopsies performed in the outpatient setting were identified: There were 592 transplant and 133 native biopsies including 3 solitary kidney biopsies. All were performed under ultrasound guidance using a 16G or 18G needle, with freehand technique...
2018: Nephron
https://www.readbyqxmd.com/read/29279869/bilateral-renal-anastomosing-hemangiomas-a-tale-of-two-kidneys
#8
Hamid Abboudi, Benjamin Tschobotko, Christopher Carr, Ranan DasGupta
Background: Renal anastomosing hemangioma (RAH) is an extremely rare benign vascular tumor first described in 2009. Making this diagnosis is fraught with challenges. Radiologically they share features consistent with renal cell carcinomas (RCCs). Their vascular nature poses risks if considering preoperative biopsy and histologically they share characteristics akin to angiosarcomas. The few reports published in the literature suggest presentation with hematuria, flank pain, and polycythemia although the majority are diagnosed at postnephrectomy histologic examination...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29259863/expanded-dengue-syndrome-in-secondary-dengue-infection-a-case-of-biopsy-proven-rhabdomyolysis-induced-acute-kidney-injury-with-intracranial-and-intraorbital-bleeds
#9
Ghazal Tansir, Chhavi Gupta, Shubham Mehta, Prabhat Kumar, Manish Soneja, Ashutosh Biswas
Dengue fever is endemic in the Indian subcontinent and can have myriad presentations. The term expanded dengue syndrome (EDS) is used for atypical manifestations in dengue fever. We present a rare case of EDS in a patient with secondary dengue infection who developed rhabdomyolysis induced acute kidney injury (RAKI) along with intracranial and intraorbital bleeds. Patient was successfully managed in our institute and was discharged in stable condition. To the best of our knowledge, this is the only reported case of simultaneous occurrence of these complications in a dengue patient...
November 2017: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/29225800/recommendations-for-imaging-based-diagnosis-and-management-of-renal-angiomyolipoma-associated-with-tuberous-sclerosis-complex
#10
REVIEW
María José Buj Pradilla, Teresa Martí Ballesté, Roser Torra, Felipe Villacampa Aubá
Renal angiomyolipomas are found in up to 80% of tuberous sclerosis complex (TSC) patients. Although these tumours are usually asymptomatic, lesions >3 cm in diameter are prone to bleeding and up to 10% of TSC patients may experience a massive and potentially fatal retroperitoneal haemorrhage. Diagnosis can be complicated because of the initial lack of symptoms and the fat-poor content of atypical renal angiomyolipomas. After diagnosis, tumour growth and the emergence of new tumours must be monitored. Treatment with mammalian target of rapamycin (mTOR) inhibitors can reduce tumour size and is indicated in patients with TSC-associated renal angiomyolipomas >3 cm in diameter...
December 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29154749/complications-and-monitoring-of-percutaneous-renal-biopsy-a-retrospective-study%C3%A2
#11
Yvette Feldmann, Klaas Böer, Gunter Wolf, Martin Busch
BACKGROUND AND AIMS: Percutaneous renal biopsy is a necessary tool to diagnose renal diseases but complications may still occur. The aims of this study were to detect the rate of complications, possible risk factors and to identify the necessity of routine post-biopsy controls at 4 - 6, and 24 hours. MATERIALS AND METHODS: This single-center retrospective study included 500 consecutive biopsies of native and allograft kidneys performed at the Jena University Hospital...
November 20, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/29145879/allogeneic-mesenchymal-stem-cell-as-induction-therapy-to-prevent-both-delayed-graft-function-and-acute-rejection-in-deceased-donor-renal-transplantation-study-protocol-for-a-randomized-controlled-trial
#12
Qipeng Sun, Liangqing Hong, Zhengyu Huang, Ning Na, Xuefeng Hua, Yanwen Peng, Ming Zhao, Ronghua Cao, Qiquan Sun
BACKGROUND: Using kidneys from deceased donors is an available strategy to meet the growing need of grafts. However, higher incidences of delayed graft function (DGF) and acute rejection exert adverse effects on graft outcomes. Since ischemia-reperfusion injury (IRI) and ongoing process of immune response to grafts are the major causes of DGF and acute rejection, the optimal induction intervention should possess capacities of both repairing renal structure injury and suppressing immune response simultaneously...
November 16, 2017: Trials
https://www.readbyqxmd.com/read/29108097/routine-haemostasis-testing-before-transplanted-kidney-biopsy-a-cohort-study
#13
Gerhardus J A J M Kuiper, Maarten H L Christiaans, Monique H J M Mullens, Hugo Ten Cate, Karly Hamulýak, Yvonne M C Henskens
BACKGROUND: Kidney biopsy can result in bleeding complications. Pre-biopsy testing using bleeding time (BT) is controversial. New whole blood haemostasis tests, like platelet function analyser 100 (PFA-100) and multiple electrode aggregometer (MEA) might perform better. We postulated that PFA-100 would be suitable to replace BT pre-biopsy. METHODS: In 154 patients, transplanted kidney biopsies were performed after measurement of bleeding time, PFA-100, MEA, and mean platelet volume (MPV)...
November 6, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29094269/hemorrhagic-shock-due-to-bleeding-from-an-arteriovenous-fistula-after-allograft-biopsy-in-a-kidney-transplant-recipient-a-case-report
#14
Akihiro Ryuge, Masahiko Yazawa, Kazuki Kitajima, Ryuto Nakazawa, Hideo Sasaki, Tatsuya Chikaraishi, Yugo Shibagaki
Arteriovenous fistula (AVF) after allograft biopsy occurs in 1.6-8.3% of kidney transplant patients and most cases remain asymptomatic. Here, we report a case of hemorrhagic shock in a kidney transplant recipient following bleeding from an AVF after graft biopsy. Immediate intensive care including angiographic embolization saved the patient and the allograft. A 62-year-old woman with end-stage renal disease caused by diabetic nephropathy underwent ABO-incompatible kidney transplantation. No complications occurred in the early postoperative period...
November 1, 2017: CEN Case Reports
https://www.readbyqxmd.com/read/28895103/a-case-of-perirenal-extramedullary-hematopoiesis-in-a-patient-with-primary-myelofibrosis
#15
Kentaro Imai, Tomonori Aoi, Hiroki Kitai, Nobuhide Endo, Masahiko Fujino, Shizunori Ichida
Extramedullary hematopoiesis (EMH) is hematopoiesis in organs outside the bone marrow and most frequently occurs in the liver, spleen, and lymph nodes. We report a case of perirenal EMH revealed by kidney biopsy in a patient with primary myelofibrosis. We observed only bilateral kidney enlargement with plain computed tomography (CT) and ultrasonography before obtaining a renal biopsy. We obtained a percutaneous biopsy from the lower pole of the left kidney using ultrasonographic guidance. Ultrasonography just after the renal biopsy revealed no bleeding around the kidney...
November 2017: CEN Case Reports
https://www.readbyqxmd.com/read/28794871/bleeding-complications-post-ultrasound-guided-renal-biopsy-a-single-centre-experience-from-pakistan
#16
Rabeea Azmat, Abdul Basit Siddiqui, M Tahir Rizwan Khan, Shiyam Sunder, Waqar Kashif
INTRODUCTION: Renal biopsy is the diagnostic modality of choice for the diagnosis of renal parenchymal diseases. The advent of improved imaging techniques and biopsy needles over the years has increased the safety of the procedure and the ability to obtain adequate renal tissue for diagnosis. However, there is paucity of data in this regard from Pakistan. This study shall help in establishing the local perspective of the frequency of bleeding complications in percutaneous ultrasound guided renal biopsy...
September 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28762683/-gross-hematuria-after-kidney-biopsy-a-case-report
#17
Rocco Manganelli, Salvatore Iannaccone, Giulio Lombardi, Michele De Siero, Lucia Lago, Giuseppe Desiderio, Emanuele De Simone, Michelangelo Viscione, Carmine Tirri
We describe the clinical case of a patient experiencing severe gross hematuria causing clotting in the renal pelvis, after undergoing a kidney biopsy.The ecocolordopper and CT angiography performed did not reveal the cause of hematuria.The kidney arteriography allowed the diagnosis, revealing an arteriovenous fistula responsible for bleeding together with a small false aneurysm in the lower pole of the biopsied kidney. Both lesions were successfully treated with superselective embolization with microcoils. We discuss about the diagnostic and therapeutic approach of these rare post-biopsy complications briefly focusing on the technical aspects and on possible risks that the transcatheter embolotherapy may result...
August 1, 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28719978/optimizing-rna-extraction-of-renal-papilla-biopsy-tissue-in-kidney-stone-formers-a-new-methodology-for-genomic-study
#18
Kazumi Taguchi, Manint Usawachintachit, Shuzo Hamamoto, Rei Unno, David T Tzou, Benjamin A Sherer, Yongmei Wang, Atsushi Okada, Marshall L Stoller, Takahiro Yasui, Thomas Chi
INTRODUCTION: Endoscopic tools have provided versatile examination and treatment for kidney stone procedures. Despite endourologists researching urinary stone disease using endoscopes to collect tissue, this tissue collection method is limited. Endoscopically removed tissues are small in size, restricting the types of genome-based examination possible. We investigated a new method of renal papilla biopsy and RNA extraction to establish a genomic research methodology for kidney stone disease...
September 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28718664/short-term-complications-for-percutaneous-ultrasound-guided-biopsy-of-renal-masses-in-adult-outpatients
#19
Lars René Rasmussen, Martina Loft, Tommy Kjærgaard Nielsen, Marie Bjødstrup Jensen, Søren Høyer, Arne Hørlyck, Ole Graumann
Background Ultrasound-guided percutaneous kidney tumor biopsy (UGPKB) plays an important role in the diagnosis of renal tumor but there are no consensuses with respect to the length and the extend of the post-biopsy observation period. Purpose To assess the short-term complication rate after UGPKB and to evaluate whether the onset of complications allows for the procedure to be performed in an outpatient setting with same-day discharge. Material and Methods Between March 2012 and March 2014, a total of 287 UGPKB were performed in an outpatient setting at a Danish university referral center...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28696022/outcomes-in-pancreas-transplantation-with-exocrine-drainage-through-a-duodenoduodenostomy-versus-duodenojejunostomy
#20
J P Lindahl, R Horneland, E Nordheim, A Hartmann, E M Aandahl, K Grzyb, H Haugaa, G Kjøsen, A Åsberg, T Jenssen
Until recently, pancreas transplantation has mostly been performed with exocrine drainage via duodenojejunostomy (DJ). Since 2012, DJ was substituted with duodenoduodenostomy (DD) in our hospital, allowing endoscopic access for biopsies. This study assessed safety profiles with DD versus DJ procedures and clinical outcomes with the DD technique in pancreas transplantation. DD patients (n = 117; 62 simultaneous pancreas-kidney [SPKDD ] and 55 pancreas transplantation alone [PTADD ] with median follow-up 2...
January 2018: American Journal of Transplantation
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