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https://www.readbyqxmd.com/read/29218669/laparoscopy-as-a-useful-selection-tool-for-patients-with-prior-surgery-and-peritoneal-metastases-suitable-for-multimodality-treatment-strategies
#1
Philipp von Breitenbuch, Thomas Boerner, Tonia Jeiter, Pompiliu Piso, Hans J Schlitt
BACKGROUND: Complete macroscopic cytoreduction in patients with peritoneal carcinomatosis (PC) is the basic requirement for long-term survival. Diagnostic laparoscopy (DL) can be difficult and of limited clinical value secondary to postoperative or tumor-induced adhesions. The aim of this study was to evaluate the role of DL in patients with prior surgery and PC. METHODS: The database of the surgical department of the University Medical Center of Regensburg was reviewed (9/2010-10/2014) selecting for DL in patients with PC...
December 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29214884/adjuvant-intraperitoneal-chemotherapy-for-the-treatment-of-colorectal-cancer-at-risk-for-peritoneal-carcinomatosis-a-systematic-review
#2
Paul L Feingold, Nicholas D Klemen, Mei Li M Kwong, Barry Hashimoto, Udo Rudloff
BACKGROUND: The peritoneal surface is the second most common site of disease recurrence, after the liver, following definitive surgery for colorectal cancer. Adjuvant intraperitoneal (IP) chemotherapy delivered at time of surgical resection has the potential to delay or prevent future spread to the peritoneal surface and improve clinical outcome. The exact role of adjuvant IP chemotherapy in colorectal cancer, including its associated morbidity and mortality, is not well defined. STUDY DESIGN: Systematic review and pooled random effect analysis of comparative trials examining the addition of adjuvant IP chemotherapy compared to surgery alone in colorectal cancer...
December 7, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29211618/outcome-and-prognostic-factors-in-stage-iii-favorable-histology-wilms-tumor-a-report-from-the-children-s-oncology-group-study-aren0532
#3
Conrad V Fernandez, Elizabeth A Mullen, Yueh-Yun Chi, Peter F Ehrlich, Elizabeth J Perlman, John A Kalapurakal, Geetika Khanna, Arnold C Paulino, Thomas E Hamilton, Kenneth W Gow, Zelig Tochner, Fredric A Hoffer, Janice S Withycombe, Robert C Shamberger, Yeonil Kim, James I Geller, James R Anderson, Paul E Grundy, Jeffrey S Dome
Background The National Wilms Tumor Study (NWTS) approach to treating stage III favorable-histology Wilms tumor (FHWT) is Regimen DD4A (vincristine, dactinomycin, and doxorubicin) and radiation therapy. Further risk stratification is required to improve outcomes and reduce late effects. We evaluated clinical and biologic variables for patients with stage III FHWT without combined loss of heterozygosity (LOH) at chromosomes 1p and 16q treated in the Children's Oncology Group protocol AREN0532. Methods From October 2006 to August 2013, 588 prospectively treated, centrally reviewed patients with stage III FHWT were treated with Regimen DD4A and radiation therapy...
December 6, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29194906/radical-gastric-cancer-surgery-results-in-widespread-upregulation-of-pro-tumourigenic-intraperitoneal-cytokines
#4
Andrew J Long, Paul R Burton, Michael J De Veer, Geraldine J Ooi, Cheryl P Laurie, Peter D Nottle, Matthew J Watt, Wendy A Brown
BACKGROUND: Radical surgical resection is the mainstay of curative treatment for oesophagogastric malignancy. However, survival and recurrence rates remain poor. Theoretical data suggests that the inflammatory response to surgery can promote tumour recurrence. The local and systemic inflammatory response to radical oesophagogastric cancer surgery has not been fully characterized. We aimed to measure this response, particularly factors associated with tumour implantation. METHODS: Consecutive patients undergoing radical junctional or gastric cancer resection over 12 months were recruited...
November 30, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29192740/bilateral-parotid-gland-metastases-from-gastric-signet-ring-cell-carcinoma
#5
Federico Nichetti, Federica Morano, Alessandra Fabbri, Filippo de Braud, Maria Di Bartolomeo
INTRODUCTION: Signet-ring cell (SRC) carcinoma is a common subtype of gastric adenocarcinoma associated with poor prognosis. Metastatic involvement of the parotid gland has been reported in gastric cancer patients, but never bilaterally nor in association with the SRC histotype. Here, we report the first case and a brief review of the literature. CASE DESCRIPTION: A 47-year-old woman was referred to our center for a signet-ring gastric carcinoma with synchronous hepatic and peritoneal metastases...
November 22, 2017: Tumori
https://www.readbyqxmd.com/read/29179680/stercoral-colitis-complicated-with-ischemic-colitis-a-double-edge-sword
#6
Maliha Naseer, Jenil Gandhi, Noor Chams, Zain Kulairi
BACKGROUND: Stercoral colitis is a rare inflammatory process involving the colonic wall secondary to fecal impaction with high morbidity and mortality; especially if complicated with ischemic colitis, stercoral ulcer formation and subsequent perforation. There are several case reports published on abdominal perforation resulting from stercoral colitis. However, stercoral colitis complicated by ischemic colitis is rare. The purpose of this case report is to describe the potential challenges in the diagnosis and management of stercoral colitis with ischemic colitis...
November 28, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29169714/-idiopathic-nephrotic-syndrome
#7
O Boyer, V Baudouin, E Bérard, C Dossier, V Audard, V Guigonis, I Vrillon
Nephrotic syndrome (NS) is defined by massive proteinuria and hypoalbuminemia, with resulting hyperlipidemia and edema. The most common cause of NS in children is idiopathic nephrotic syndrome (INS), also called nephrosis. Its annual incidence has been estimated to 1-4 per 100,000 children and varies with age, race, and geography. Many agents or conditions have been reported to be associated with INS such as infectious diseases, drugs, allergy, vaccinations, and malignancies. The disease may occur during the 1st year of life, but it usually starts between the ages of 2 and 7 years...
December 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/29169160/the-use-of-peritoneal-dialysis-in-phenobarbitone-toxicity-in-a-critically-unwell-neonate
#8
Amelia K Le Page, Alice E Stewart, Charles C Roehr, Lilian M Johnstone, Andis Graudins
BACKGROUND: Phenobarbitone (PB) is the first-line anti-convulsant for neonatal seizures. The use of peritoneal dialysis (PD) to enhance drug elimination in cases of neonatal PB overdose has not been reported. OBJECTIVE: To report a case of neonatal severe PB toxicity and review the elimination of PB by PD. METHODS: Assessment of PD drug clearance. RESULTS: A neonate with prolonged seizures was administered PB. Encephalopathy and myocardial failure developed, which were initially suspected to be secondary to hypoxia...
November 24, 2017: Neonatology
https://www.readbyqxmd.com/read/29141481/liposome-supported-peritoneal-dialysis-in-rat-amitriptyline-exposure-with-and-without-intravenous-lipid-emulsion
#9
Robin Chapman, Martyn Harvey, Paul Davies, Zimei Wu, Grant Cave
INTRODUCTION: Liposome supported peritoneal dialysis is a recently described technique which may eventually be applicacle in the clinical scenario of the intoxicated patient. We evaluated the hypothesis that intravenous injection lipid emulsion (ILE) would augment acidic pH gradient liposome supported peritoneal dialysis (LSPD). METHODS: Orogastrically amitriptyline dosed rats were treated with either NaHCO3 intravenously and standard intraperitoneal dialysate (A); NaHCO3 intravenously and LSPD (B); or ILE and LSPD (C)...
November 15, 2017: Journal of Liposome Research
https://www.readbyqxmd.com/read/29130006/incidental-laparoscopic-discovery-of-an-intraperitoneal-plastic-catheter-16-years-after-an-unsafe-abortion-a-case-report-from-the-gynecologic-obstetric-and-pediatric-hospital-of-yaound%C3%A3-cameroon
#10
Ngandji Andre, Ngo Um Meka Esther Juliette, Fokom Joel, Wandji Brigitte, Foumane Pascal
In many developing countries like Cameroon, unsafe abortion is a major public health problem. It can be responsible for severe complications including damage to the digestive and/or urinary tract, sepsis, and uterine perforation. Uterine perforation could be caused by most of the instruments that are used to evacuate the uterus. We report a case of apparent uterine perforation and subsequent migration of the plastic or rubber catheter into the peritoneal cavity during an abortion procedure performed in a setting that may have been unsafe...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29120457/management-of-neonatal-spontaneous-intestinal-perforation-by-peritoneal-needle-aspiration
#11
M Gébus, J-L Michel, S Samperiz, L Harper, J-L Alessandri, D Ramful
OBJECTIVE: To describe conservative management of spontaneous intestinal perforation (SIP) in preterm infants using peritoneal needle aspiration (PNA). STUDY DESIGN: Monocentric retrospective review of SIP cases treated primarily by PNA between 1999 and 2015 (n=31). RESULTS: Mean gestational age was 29.2±2.4 weeks and birthweight 1149±428 g. SIP occurred at 3.7±2.2 days of life. PNA achieved definitive treatment in 18 patients (60%) with a mean of 1...
November 9, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29112915/acute-abdomen-secondary-to-a-spontaneous-perforation-of-the-biliary-tract-a-rare-complication-of-choledocholithiasis
#12
G A Gómez-Torres, F M Rodríguez-Navarro, C R López-Lizárraga, C A Bautista-López, O S Ortega-García, G Becerra-Navarro, A Águila-Barragán, C F Ploneda-Valencia
INTRODUCTION: The spontaneous perforation of the biliary tract (SPBT) is an extremely rare cause of peritonitis, which was first described by Freeland in 1982, to date only around 70 cases have been reported. Here we present a case of spontaneous perforation of the biliary tract, in a patient with choledocholithiasis, which was treated with ultrasound-guided drainage and ERCP. CASE REPORT: A 51-year-old male was admitted to the emergency room for 15-day evolution jaundice, localized pain in the right flank and hypochondrium of 3days...
October 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29103634/efficacy-of-endoscopic-third-ventriculostomy-in-old-aged-patients-with-normal-pressure-hydrocephalus
#13
Young Sill Kang, Eun-Kyung Park, Ju-Seong Kim, Dong-Seok Kim, Ulrich-Wilhelm Thomale, Kyu-Won Shim
Normal pressure hydrocephalus (NPH) is a chronic disorder caused by interrupted CSF absorption or flow. Generally, shunt placement is first option for NPH treatment. Due to complications of ventriculo-peritoneal (VP) shunt placement, endoscopic third ventriculostomy (ETV) can be considered as an alternative treatment option. Here we report the efficacy of ETV especially in old aged patients with normal pressure hydrocephalus. Total 21 old aged patients with communicating hydrocephalus with opening pressure, measured via lumbar puncture, less than 20cm H2O underwent ETV...
October 23, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29099149/closure-methods-for-laparotomy-incisions-for-preventing-incisional-hernias-and-other-wound-complications
#14
REVIEW
Sunil V Patel, David D Paskar, Richard L Nelson, Satyanarayana S Vedula, Scott R Steele
BACKGROUND: Surgeons who perform laparotomy have a number of decisions to make regarding abdominal closure. Material and size of potential suture types varies widely. In addition, surgeons can choose to close the incision in anatomic layers or mass ('en masse'), as well as using either a continuous or interrupted suturing technique, of which there are different styles of each. There is ongoing debate as to which suturing techniques and suture materials are best for achieving definitive wound closure while minimising the risk of short- and long-term complications...
November 3, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29098551/ascites-neutrophil-gelatinase-associated-lipocalin-identifies-spontaneous-bacterial-peritonitis-and-predicts-mortality-in-hospitalized-patients-with-cirrhosis
#15
Giuseppe Cullaro, Grace Kim, Marcus R Pereira, Robert S Brown, Elizabeth C Verna
BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) is a marker of both tissue injury and infection. Urine NGAL levels strongly predict acute kidney injury and mortality in patients with cirrhosis, but ascites NGAL is not well characterized. We hypothesized that ascites NGAL level is a marker of spontaneous bacterial peritonitis (SBP) and mortality risk in patients with cirrhosis. METHODS: Hospitalized patients with cirrhosis and ascites undergoing diagnostic paracentesis were prospectively enrolled and followed until death or discharge...
December 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29081384/secondary-laparoscopic-cytoreduction-in-recurrent-ovarian-cancer-a-large-single-institution-experience
#16
Gallotta Valerio, Conte Conte, Giudice Maria Teresa, Nero Camilla, Vizzielli Giuseppe, Gueli Alletti Salvatore, Cianci Stefano, Lodoli Claudio, Di Giorgio Andrea, De Rose Agostino Maria, Fagotti Anna, Scambia Giovanni, Ferrandina Gabriella
STUDY OBJECTIVE: To analyze the feasibility and safety of laparoscopic secondary cytoreductive surgery in a retrospective series of platinum sensitive recurrent ovarian cancer patients. DESIGN: Retrospective cohort study (Canadian Task Force classification II-2). SETTING: Catholic University of the Sacred Hearth, Rome, Italy. PATIENTS: Between October 2010 and October 2016, 58 patients with recurrent ovarian cancer were selected for a retrospective analysis of data...
October 25, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29069247/reversal-of-uremic-tumoral-calcinosis-by-optimization-of-clinical-treatment-of-bone-and-mineral-metabolism-disorder
#17
Mariana Espiga Maioli, Vinicius Daher Alvares Delfino, Amanda Carolina Damasceno Zanuto Guerra, Luiz Fernando Kunii, Raquel Ferreira Nassar Frange
Tumoral calcinosis is an uncommon type of extraosseous calcification characterized by large rubbery or cystic masses containing calcium-phosphate deposits. The condition prevails in the periarticular tissue with preservation of osteoarticular structures. Elevated calcium-phosphorus products and severe secondary hyperparathyroidism are present in most patients with uremic tumoral calcionosis (UTC). Case report of an obese secondary to chronic glomerulonephritis, undergoing continuous ambulatory peritoneal dialysis (CAPD) reported the appearance of painless tumors in the medial surface of fifth finger and left arm...
April 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29067525/hypernatremia-and-acute-pancreatitis-in-chronic-kidney-disease-back-to-the-salt-mines-questions
#18
Marie de Tersant, Thérésa Kwon, Marie-Alice Macher, Anne Maisin, Georges Deschênes, Olivier Niel
BACKGROUND: Acute pancreatitis can be a life-threatening complication in patients with chronic kidney disease (CKD), especially in kidney transplant recipients. CASE DIAGNOSIS/TREATMENT: The patient was 7 years old when he received renal transplantation for CKD secondary to posterior urethral valves. Two years later, he presented with severe necrotizing pancreatitis (Ranson's score 5, Balthazar's score 8). Viral and genetic testing came back negative; pancreatitis was attributed to the patient's treatments (prednisone, trimethoprim-sulfamethoxazole, and everolimus)...
October 24, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29051974/cardiac-disease-in-familial-mediterranean-fever
#19
REVIEW
Eren Erken, Ertugrul Erken
Familial Mediterranean fever (FMF) is an autoinflammatory disease manifested by inflammatory attacks of peritonitis, pleuritis, pericarditis accompanied by fever and arthritis. Mutations of MEFV gene results in pyrin dysfunction, which causes uncontrolled interleukin-1 beta production and triggers the inflammatory attacks. Inflammation persists even during attack-free periods in one-third of the FMF patients. Findings of elevated proinflammatory cytokine patterns during remission as well as inflammatory attacks indicate the continuous subclinical disease activity and inflammation...
October 20, 2017: Rheumatology International
https://www.readbyqxmd.com/read/29044930/effect-of-incident-nocturnal-home-hemodialysis-versus-incident-continuous-ambulatory-peritoneal-dialysis-on-employment-rate-clinical-and-laboratory-outcomes-a-1-year-retrospective-observation-study
#20
John Wing Li, Joseph Ho Sing Wong, Wai Leung Chak, Ka Foon Chau
INTRODUCTION: While studies demonstrated favorable outcomes of nocturnal home hemodialysis (NHHD), direct comparison on employment rate, clinical and laboratory outcomes between the NHHD and continuous ambulatory peritoneal dialysis (CAPD) had not been previously performed. METHODS: A 1-year retrospective observation study was performed in 20 incidents alternate night NHHD and 81 incident CAPD patients of Chinese ethnicity, who were sex, diabetic status, and Charlson comorbidity index matched, but not age due to our center's age limit for NHHD enrollment...
October 18, 2017: Hemodialysis International
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