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https://www.readbyqxmd.com/read/28637862/multicenter-registry-analysis-of-center-characteristics-associated-with-technique-failure-in-patients-on-incident-peritoneal-dialysis
#1
Htay Htay, Yeoungjee Cho, Elaine M Pascoe, Darsy Darssan, Annie-Claire Nadeau-Fredette, Carmel Hawley, Philip A Clayton, Monique Borlace, Sunil V Badve, Kamal Sud, Neil Boudville, Stephen P McDonald, David W Johnson
BACKGROUND AND OBJECTIVES: Technique failure is a major limitation of peritoneal dialysis. Our study aimed to identify center- and patient-level predictors of peritoneal dialysis technique failure. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: All patients on incident peritoneal dialysis in Australia from 2004 to 2014 were included in the study using data from the Australia and New Zealand Dialysis and Transplant Registry. Center- and patient-level characteristics associated with technique failure were evaluated using Cox shared frailty models...
June 21, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28631827/one-year-results-of-the-scandiv-randomized-clinical-trial-of-laparoscopic-lavage-versus-primary-resection-for-acute-perforated-diverticulitis
#2
J K Schultz, C Wallon, L Blecic, H M Forsmo, J Folkesson, P Buchwald, H Kørner, F A Dahl, T Øresland, S Yaqub
BACKGROUND: Recent randomized trials demonstrated that laparoscopic lavage compared with resection for Hinchey III perforated diverticulitis was associated with similar mortality, less stoma formation but a higher rate of early reintervention. The aim of this study was to compare 1-year outcomes in patients who participated in the randomized Scandinavian Diverticulitis (SCANDIV) trial. METHODS: Between February 2010 and June 2014, patients from 21 hospitals in Norway and Sweden presenting with suspected perforated diverticulitis were enrolled in a multicentre RCT comparing laparoscopic lavage and sigmoid resection...
June 20, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28629465/natural-igm-antibodies-that-bind-neoepitopes-exposed-as-a-result-of-spinal-cord-injury-drive-secondary-injury-by-activating-complement
#3
Aarti Narang, Fei Qiao, Carl Atkinson, Hong Zhu, Xiaofeng Yang, Liudmila Kulik, V Michael Holers, Stephen Tomlinson
BACKGROUND: Natural IgM antibodies (Abs) function as innate immune sensors of injury via recognition of neoepitopes expressed on damaged cells, although how this recognition systems function following spinal cord injury (SCI) exposes various neoepitopes and their precise nature remains largely unknown. Here, we investigated the role of two natural IgM monoclonal Abs (mAbs), B4 and C2, that recognize post-ischemic neoepitopes following ischemia and reperfusion in other tissues. METHODS: Identification of post-SCI expressed neoepitopes was examined using previously characterized monoclonal Abs (B4 and C2 mAbs)...
June 19, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/28610918/cd155-blockade-improves-survival-in-experimental-sepsis-by-reversing-dendritic-cell-dysfunction
#4
Yan Meng, Zhenzhen Zhao, Wenzhong Zhu, Tao Yang, Xiaoming Deng, Rui Bao
Immunosuppression is involved in septic processes, and results in an inability to eradicate the primary infection as well as a propensity to acquire secondary infections. In the present study, we found that the expression of CD155 on dendritic cells (DCs) and TIGIT on T cells were strikingly increased in septic mice. Furthermore, anti-CD155 antibody treatment could improve survival rate in mouse sepsis models through deceasing bacterial burden in both blood and peritoneal lavage fluid. Meanwhile, CD155 blockade efficiently increased the expression of TNF-a, IL-6 and decreased the level of IL-10 in blood and peritoneal lavage fluid of septic mice...
June 10, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28601305/survival-benefits-of-remote-ischemic-conditioning-in-sepsis
#5
Bellal Joseph, Mazhar Khalil, Ammar Hashmi, Louise Hecker, Narong Kulvatunyou, Andrew Tang, Randall S Friese, Peter Rhee
BACKGROUND: Sepsis remains the leading cause of death in the surgical intensive care unit. Prior studies have demonstrated a survival benefit of remote ischemic conditioning (RIC) in many disease states. The aim of this study was to determine the effects of RIC on survival in sepsis in an animal model and to assess alterations in inflammatory biochemical profiles. We hypothesized that RIC alters inflammatory biochemical profiles resulting in decreased mortality in a septic mouse model...
June 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28598731/neoplasms-of-the-appendix-pictorial-review-with-clinical-and-pathologic-correlation
#6
Laura M Leonards, Anokh Pahwa, Maitraya K Patel, Jeffrey Petersen, Michael J Nguyen, Cecilia M Jude
Appendiceal neoplasms are uncommon tumors of the gastrointestinal tract that may manifest with symptoms of appendicitis, right lower quadrant pain, or palpable mass, leading to imaging or surgical intervention. The majority of appendiceal masses consist of primary epithelial neoplasms and neuroendocrine tumors (NETs). Epithelial neoplasms-mucinous and nonmucinous types-are more often detected at imaging than NETs due to their larger size and propensity for peritoneal spread and metastatic disease. Epithelial mucinous neoplasms are defined by the presence of mucin, detected at radiologic and pathologic examination...
June 9, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28590295/68ga-psma-pet-mr-positive-peritoneal-metastasis-in-the-falciform-ligament-in-recurrent-prostate-cancer
#7
Benedikt Kranzbühler, Sébastien Tran, Thomas Zilli, Irene A Burger
Synchronous or metachronous metastases develop in approximately one third of all prostate cancer (PCa) patients. Main sites of metastasis include lymph nodes, bone, lung and liver. Secondary peritoneal carcinomatosis is very rare in PCa, with only a few published cases. Ga-PSMA PET-based imaging is a promising tool for staging and restaging PCa. We report a case of Ga-PSMA PET/MR-positive peritoneal metastasis as site of primary relapse after definitive PCa treatment in a 58-year-old man with a prostate-specific antigen of 30 ng/mL at time of the study...
June 5, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28589875/secondary-peritonitis-associated-with-infective-endocarditis-and-vertebral-osteomyelitis-in-a-peritoneal-dialysis-patient
#8
Yao-Ko Wen
No abstract text is available yet for this article.
June 7, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28589314/the-health-related-quality-of-life-of-chinese-patients-on-hemodialysis-and-peritoneal-dialysis
#9
Julie Yun Chen, Eric Yuk Fai Wan, Edmond Pui Hang Choi, Anca Ka Chun Chan, Karina Hiu Yen Chan, Joyce Pui Yan Tsang, Cindy Lo Kuen Lam
AIMS: Our aim was to compare health-related quality of life (HRQOL) between end-stage renal disease (ESRD) patients and the Hong Kong general population to identify how the mode of dialysis and other factors were associated with HRQOL. METHODS: We conducted a cross-sectional study involving 253 hemodialysis (HD) patients and 103 peritoneal dialysis (PD) patients recruited in 2014-2015. Their HRQOL was evaluated using Kidney Disease and Quality of Life-36 (KDQOL-36) sub-scale scores and the Short Form-6 Dimensions (SF-6D) health preference score...
June 6, 2017: Patient
https://www.readbyqxmd.com/read/28584681/abdominal-pseudocyst-as-a-complication-of-ventriculoperitoneal-shunt-placement-review-of-the-literature-and-a-proposed-algorithm-for-treatment-using-4-illustrative-cases
#10
Samir Kashyap, Hammad Ghanchi, Tanya Minasian, Fanglong Dong, Dan Miulli
BACKGROUND: Ventriculoperitoneal (VP) shunt placement is one of the most commonly performed procedures in neurosurgery. One rare complication is the formation of an abdominal pseudocyst, which can cause shunt malfunction. CASE DESCRIPTIONS: We present four unique cases of abdominal pseudocyst formation. Our first patient initially presented with a right upper quadrant pseudocyst. Shunt was externalized and the distal end was revised with placement of catheter on the opposite side...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28583791/an-18-year-population-based-study-on-site-of-origin-and-outcome-of-patients-with-peritoneal-malignancy-in-ireland
#11
J G Solon, M O'Neill, K H Chang, S Deady, R Cahill, B Moran, C Shields, J Mulsow
Peritoneal malignancy (PM) is predominantly metastatic spread from advanced gastrointestinal or gynaecological cancer. PM is generally considered incurable and therefore has rarely been the focus of novel therapeutic strategies. This study assessed patterns and survival outcomes for patients with PM in Ireland. The National Cancer Registry Ireland database was interrogated to identify patients diagnosed with PM during the period 1994-2012. Patient and tumour characteristics were retrieved and survival outcomes calculated...
May 24, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28580061/disseminated-peritoneal-leiomyomatosis-status-post-laparoscopic-hysterectomy-with-morcellation
#12
Neil Anand, Marci Handler, Ahsan Khan, Allison Wagreich, Sean Calhoun
Uterine leiomyomas (fibroids) are common benign neoplasms, which develop from the muscular tissue of the uterus with an estimated incidence of 20-40% in women of reproductive age. In the early nineties, power morcellators were introduced and became commonly used during hysterectomy for symptomatic fibroids. However, if all fragments are not removed, they may parasitize to other blood supply and present as abdominal or pelvic masses. Unfortunate cases have also been reported in which uterine sarcomas seeded throughout the abdomen and pelvis secondary to morcellation...
December 2016: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/28567101/ascites-matters
#13
REVIEW
Velauthan Rudralingam, Clare Footitt, Ben Layton
The excess accumulation of intra-peritoneal fluid, referred to as ascites, is an important clue that points to a significant underlying illness. This may be due to a pathological event within the peritoneal cavity or secondary to an underlying systemic condition. Ascites is broadly classified into transudate and exudate, based on protein content, with a potential wide range of differential diagnoses. Traditionally, computed tomography has been regarded as the imaging modality of choice to demonstrate ascites and diagnose the underlying cause...
May 2017: Ultrasound: Journal of the British Medical Ultrasound Society
https://www.readbyqxmd.com/read/28559702/tubercular-abdominal-cocoon-in-children-a-single-centre-study-in-remote-area-of-northern-india
#14
Rikki Singal, B Satyashree, Amit Mittal, Bhanu Pratap Sharma, Samita Singal, Muzzafarr Zaman, Parteek Shardha
BACKGROUND: Amongst the numerous causes of intestinal obstruction listed in the literature, sclerosing encapsulating peritonitis also called Abdominal Cocoon (AC) is one of the rarest entities. Its characteristic feature is a thick fibrotic membrane encasing varying lengths of the small and large gut in a cocoon. In India, there is an increasing incidence of tuberculosis, especially in the rural areas. AIMS AND OBJECTIVES: The aim of this study was to investigate the clinical presentation and evaluate the operative findings of tuberculous AC...
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/28557369/medical-mishap-as-a-cause-of-non-resolving-pneumonia
#15
Yazeed Toukan, Michal Gur, Vered Nir, Lea Bentur
A 15-year old boy was referred for evaluation of fever, productive cough, and recurrent/persistent right lower lobe (RLL) pneumonia of 1-month duration. Chest computed tomography scan showed RLL consolidation, with minimal pleural effusion and a liver abscess with sharp borders, containing a solid calcification in the lower portion. History revealed acute appendicitis with laparoscopic appendectomy 6 months prior to presentation, during which a fecalith dropped to the peritoneal cavity. Following laparoscopically guided drainage of the abscess the patient improved...
May 30, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28555652/reducing-the-costs-of-chronic-kidney-disease-while-delivering-quality-health-care-a-call-to-action
#16
REVIEW
Raymond Vanholder, Lieven Annemans, Edwina Brown, Ron Gansevoort, Judith J Gout-Zwart, Norbert Lameire, Rachael L Morton, Rainer Oberbauer, Maarten J Postma, Marcello Tonelli, Wim Van Biesen, Carmine Zoccali
The treatment of chronic kidney disease (CKD) and of end-stage renal disease (ESRD) imposes substantial societal costs. Expenditure is highest for renal replacement therapy (RRT), especially in-hospital haemodialysis. Redirection towards less expensive forms of RRT (peritoneal dialysis, home haemodialysis) or kidney transplantation should decrease financial pressure. However, costs for CKD are not limited to RRT, but also include nonrenal health-care costs, costs not related to health care, and costs for patients with CKD who are not yet receiving RRT...
July 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28555442/-the-treatment-of-acute-secondary-peritonitis-a-retrospective-analysis-of-the-use-of-continuous-negative-pressure-therapy
#17
V Müller, G Koplin, J Pratschke, W Raue
BACKGROUND: Patients with acute secondary peritonitis often need relaparotomies and open abdominal lavages. Continuous negative pressure therapy seems to be beneficial. OBJECTIVES: Does the efficacy of the therapy depend on the continuous negative pressure system used? MATERIALS AND METHODS: A retrospective analysis was performed in the Chirurgische Klinik der Universitätsmedizin Berlin, Charité Campus Mitte, including all patients who underwent abdominal vacuum therapy between December 2013 and February 2015...
May 29, 2017: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/28554937/untargeted-antifungal-therapy-in-adult-patients-with-complicated-intra-abdominal-infection-protocol-for-a-systematic-review-with-meta-analysis
#18
Marie Warrer Petersen, Anders Perner, Fredrik Sjövall, Morten Hylander Møller
INTRODUCTION: Intra-abdominal infections are the second most frequent cause of sepsis. In a recent cohort, fungal specimens were found in 51.9% of all patients with sepsis and peritonitis. Current systematic reviews comparing untargeted antifungal treatment with placebo or no treatment in patients who are critically ill have provided conflicting results, and clinical equipoise exists. Accordingly, we aim to assess patient-important benefits and harms of untargeted antifungal therapy versus placebo or no treatment in adult patients with complicated intra-abdominal infection...
May 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/28548199/-acute-small-bowel-diverticulitis-in-a-patient-with-crohn%C3%A2-s-disease
#19
Macarena Hevia, Rodrigo Quera, Leonardo Soto, Tomás Regueira, Andrés O'Brien, Andrés Larach, Udo Kronberg
Diverticular disease of the small intestine is rare, especially when it is located in the jejunum. It is generally asymptomatic, but in some patients it may have complications such as acute diverticulitis with peritonitis, gastrointestinal bleeding or obstruction. In such cases, the recommended treatment is surgery. We report a 77-year-old patient with ileal Crohn’s disease with a long-standing inflammatory phenotype, who developed acute diverticulitis of the jejunum presenting a severe septic shock and secondary multiple-organ failure...
March 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28546367/intensive-versus-minimal-standard-dosage-for-peritoneal-dialysis-in-acute-kidney-injury-a-randomized-pilot-study
#20
Watanyu Parapiboon, Treechada Chamradpan
♦Background: Dosage for peritoneal dialysis (PD) in acute kidney injury (AKI) is controversial. This study aims to find benefits and risks of intensive versus minimal standard dosage of PD in AKI. ♦ Methods: In a tertiary-hospital, 93 AKI patients who required PD between May 2015 and January 2016 were enrolled in a randomized, open-label controlled study. Patients were randomized to intensive group (> 30 L) and minimal standard group (< 20 L) of PD volume per day for the first 2 consecutive days. The primary outcome was in-hospital mortality...
May 25, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
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