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https://www.readbyqxmd.com/read/27891659/ics-teaching-module-cystometry-basic-module
#1
REVIEW
Carlos Arturo Levi D'Ancona, Mario João Gomes, Peter F W M Rosier
AIMS: To summarize the evidence background for education of good urodynamic practice, especially cystometry. METHODS: A search was done in PubMed for the last 5 years of publications selecting only clinical studies, utilizing the following keywords: cystometry 133 articles and filling cystometry 53 articles. RESULTS: The evidence with regard to clinical setting and cystometry technique, as well as for catheters and transducers type, infused solution and patient position is presented with recommendations...
November 28, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27889808/pharmacodynamic-evaluation-of-lys-5-meleu-9-nle-10-nka-4-10-prokinetic-effects-on-bladder-and-colon-activity-in-acute-spinal-cord-transected-and-spinally-intact-rats
#2
F Aura Kullmann, M Katofiasc, K B Thor, Lesley Marson
The purpose of this study was to determine feasibility of a novel therapeutic approach to drug-induced voiding after spinal cord injury (SCI) using a well-characterized, peptide, neurokinin 2 receptor (NK2 receptor) agonist, Lys(5), MeLeu(9), Nle(10)-NKA(4-10) (LMN-NKA). Cystometry and colorectal pressure measurements were performed in urethane-anesthetized, intact, and acutely spinalized female rats. Bladder pressure and voiding were monitored in response to intravenous LMN-NKA given with the bladder filled to 70% capacity...
November 26, 2016: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/27879521/tibial-nerve-stimulation-to-inhibit-the-micturition-reflex-by-an-implantable-wireless-driver-microstimulator-in-cats-retracted
#3
Xing Li, Li-Min Liao, Guo-Qing Chen, Zhao-Xia Wang, Tian-Ji Lu, Han Deng, Gerald-E Loeb
BACKGROUND: Traditional tibial nerve stimulation (TNS) has been used to treat overactive bladder syndrome (OAB), but there are some shortcomings. Thus, a novel alternative is needed for the treatment of OAB. The study investigated the effects of a new type of tibial nerve microstimulator on the micturition reflex in cats. METHODS: An implantable wireless driver microstimulator was implanted around the tibial nerve in 9 α-chloralose anesthetized cats. Cystometry was performed by infusing 0...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27845695/-prognostic-factors-for-the-efficacy-of-silodosin-in-the-treatment-of-symptomatic-benign-prostatic-hyperplasia-subanalysis-of-the-ural-study
#4
Jesús Salinas-Casado, Miguel Vírseda-Chamorro, Santiago Méndez-Rubio, Marcos Luján-Galán, Manuel Esteban-Fuertes, Jesús Moreno-Sierra
OBJECTIVE: To identify the prognostic factors influencing the clinical and urodynamics results on symptomatic benign prostatic hypertrophy (BHP) treatment in a series of patients with silodosin therapy from the URAL study. METHODS: A retrospective study was performed in a cohort of 318 patients with BPH which underwent silodosine treatment, during at least 12 weeks. RESULTS: Univariate analysis demonstrated that the variables in relationship with a decrease of urinary symptoms` punctuation postreatment (measured with the IPSS Questionnaire), a maximum peak flow (Q max) postreatment equal or superior to 15 ml/s, a postreatment postvoid residual lower to 100 ml, and a postreatment obstruction index ( Bladder Outlet Obstruction Index: BOOI) equal or lower to 20 cm H2O, presented such both as a clinical and urodynamic character...
November 2016: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/27844406/partial-bladder-outlet-obstruction-is-associated-with-decreased-expression-and-function-of-the-small-conductance-ca-2-activated-k-channel-in-guinea-pig-detrusor-smooth-muscle
#5
Ning Li, Xiaoning He, Zizheng Li, Yili Liu, Ping Wang
PURPOSE: Partial bladder outlet obstruction (PBOO) usually induces overactive bladder (OAB) associated with detrusor overactivity (DO) which is related to the increased contractility of detrusor smooth muscle (DSM). The pharmacological activation of small-conductance Ca(2+)-activated K(+) (SK) channels dramatically attenuates DSM contractility. However, the role of SK channels in the PBOO DSM is less clear. Here, we tested the hypothesis that PBOO is associated with decreased expression and function of SK channels in DSM and that the activation of SK channels is a potential target to regulate DO...
November 14, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27813141/renal-deterioration-after-spinal-cord-injury-is-associated-with-length-of-detrusor-contractions-during-cystometry-a-study-with-a-median-of-41-years-follow-up
#6
Marlene Elmelund, Niels Klarskov, Per Bagi, Peter S Oturai, Fin Biering-Sørensen
AIMS: To investigate which urodynamic parameters are associated with renal deterioration over a median of 41 years follow-up after traumatic spinal cord injury. METHODS: Medical records of patients with a traumatic spinal cord injury sustained 1944-1975 were reviewed from time of injury until 2012. Patients who attended regular renography and/or renal clearance examinations and had minimum one cystometry and pressure-flow study were included. Renal deterioration was diagnosed as split renal function ≤30% in one kidney or relative glomerular filtration rate ≤51% of expected according to age and gender...
November 4, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27802005/cystometric-analysis-of-the-transplanted-bladder
#7
Jeová Nina Rocha
OBJECTIVE: cystometric evaluation of the bladder after autotransplant and isogeneic transplant in female rats. MATERIAL AND METHODS: two groups were constituted: (A) bladder autotransplant with two subgroups: R1 - (control) and R2 - (bladder transplant); (B) isogeneic bladder transplant with three subgroups; T1 - (control); T2-T3, two subgroups observed for 30 and 60 days after transplant, respectively. All animals underwent cystometric evalua¬tion. Afterwards, the bladders were removed for histological study...
November 2, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27778388/detrusor-overactivity-increases-bladder-wall-thickness-in-male-patients-a-urodynamic-multicenter-cohort-study
#8
Cosimo De Nunzio, Fabrizio Presicce, Riccardo Lombardo, Simon Carter, Carlo Vicentini, Andrea Tubaro
AIMS: To evaluate the role of Bladder wall thickness (BWT) as a predictor of Detrusor overactivity (DO) in patients with Lower urinary tract symptoms (LUTS)/Benign prostatic enlargement without Bladder Outlet Obstruction. METHODS: From January 1996 to December 2000, each new patient, aged 45 years or older with LUTS, underwent standard diagnostic assessment, urodynamic studies (cystometry and pressure flow studies), and ultrasound measurements of the bladder wall thickness (BWT) in two centers...
October 24, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27778376/post-injury-bladder-management-strategy-influences-lower-urinary-tract-dysfunction-in-the-mouse-model-of-spinal-cord-injury
#9
Naoki Wada, Takahiro Shimizu, Shun Takai, Nobutaka Shimizu, Anthony J Kanai, Pradeep Tyagi, Hidehiro Kakizaki, Naoki Yoshimura
AIMS: To examine the effects of a different number of daily bladder squeezes on bladder dysfunction in mice with spinal cord injury (SCI). METHODS: Spinal cord was transected at the Th8/9 in female C57BL/6N mice. Their bladders were manually squeezed to eliminate urine inside every day for 4 weeks. The mice were divided into three groups depending on the number of bladder squeezes; A: once daily, B: twice daily, C: three times daily. Four weeks after transection, single-filling cystometry were performed under an awake condition...
October 24, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27778372/lumbosacral-spinal-segmental-contributions-to-tibial-and-pudendal-neuromodulation-of-bladder-overactivity-in-cats
#10
Utsav Bansal, Thomas W Fuller, Xuewen Jiang, Jathin Bandari, Zhaocun Zhang, Bing Shen, Jicheng Wang, James R Roppolo, William C de Groat, Changfeng Tai
AIMS: To determine the spinal segmental afferent contributions to tibial and pudendal inhibition of bladder overactivity. METHODS: Intravesical infusion of 0.5% acetic acid was used to irritate the bladder and induce bladder overactivity in anesthetized cats. Tibial or pudendal nerve stimulation was used to suppress the bladder overactivity and increase bladder capacity during cystometry. L5-S3 dorsal roots ipsilateral to the stimulation were exposed by a laminectomy and transected sequentially during the experiments to determine the role of individual dorsal roots in tibial or pudendal neuromodulation...
October 24, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27778361/are-voiding-parameters-a-marker-for-the-severity-of-quality-of-life-impairment-in-women-with-overactive-bladder-symptoms
#11
Maya Basu, Stergios K Doumouchtsis
AIMS: There is evidence of an association between voiding parameters and the presence of overactive bladder symptoms. The aim of this study was to evaluate whether there is any association between pressure flow study parameters and the degree of health related quality of life impairment in women with OAB symptoms. The null hypothesis is that there is no significant correlation between quality of life domain scores and pressure flow study parameters. METHODS: One hundred and sixty-seven consecutive women with overactive bladder symptoms underwent evaluation with a quality of life assessment plus filling and voiding cystometry...
October 24, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27776992/routine-enema-before-urodynamics-has-no-impact-on-the-quality-of-abdominal-pressure-curves-results-of-a-prospective-controlled-study
#12
H Rigole, N Senal, M Damphousse, C Brochard, A Manunta, J Kerdraon, L Tondut, Q Alimi, J Hascoet, L Siproudhis, B Peyronnet, I Bonan
AIMS: The presence of stools in the rectum might affect the quality of the abdominal pressure curve during filling cystometry, but, to date, no study has evaluated the impact of bowel preparation before urodynamics. We evaluated the influence of a sodium phosphate enema before urodynamics on the quality of the abdominal pressure curve. METHODS: A prospective, controlled, single-blind study was conducted in a single center from May to June 2013. The patients were divided into 2 consecutive groups: patients seen in outpatient clinics during the first 6 weeks (group A) who underwent urodynamics without bowel preparation and patients seen in outpatient clinics during the second 6 weeks (group B) who had a prescription of sodium phosphate enema before urodynamics...
December 2016: Progrès en Urologie
https://www.readbyqxmd.com/read/27751414/effect-of-umbilical-cord-blood-stem-cells-transplantation-on-bladder-dysfunction-induced-by-cerebral-ischemia-in-rats
#13
Ching-Chung Liang, Tsong-Hai Lee, Shuenn-Dhy Chang
OBJECTIVE: To demonstrate the effect of human umbilical cord blood-derived CD34(+) cells on bladder dysfunction induced by cerebral ischemia in rats. MATERIALS AND METHODS: Female rats were subjected to either 60 minute middle cerebral artery occlusion (MCAO) or a sham operation. Rats were divided into four groups: sham operation, MCAO without treatment, infusion with 1×10(6) CD34(+) cells 30 minutes before MCAO, and infusion with 1×10(6) CD34(+) cells 3 hours after MCAO...
October 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27750360/pharmacological-properties-of-propiverine-contribute-to-improving-lower-urinary-tract-dysfunctions-in-rats-with-spinal-cord-injuries
#14
F Sakakibara, K Takahama, M Nanri, E Sasaki
Patients with spinal cord injury (SCI) usually develop lower urinary tract dysfunctions, including detrusor overactivity which is also known to be a risk factor for upper urinary tract dysfunction. Antimuscarinic agents, such as propiverine, have been used clinically for the treatment of detrusor overactivity. Also, propiverine has been known to possess antagonistic activity against L-type Ca(2+) channels and transient receptor potential vanilloid subtype 1 (TRPV1), in addition to activity against muscarinic receptors...
September 2016: Drug Research
https://www.readbyqxmd.com/read/27721639/role-of-urodynamics-in-stress-urinary-incontinence-a-critical-appraisal
#15
Shirish Dattatraya Yande, Omkar Vinay Joglekar, Maya Joshi
INTRODUCTION: Role of urodynamics prior to surgery of stress urinary incontinence (SUI) is under constant debate. Demonstration of the presence of detrusor overactivity is the only aspect that has been emphasized in the literature so far. We believe that there are number of other factors which may influence the evaluation and in turn the choice of surgical management and prediction of outcome of treatment. They are as follows: (1) Presence of voiding inefficiency, (2) asymptomatic detrusor overactivity, (3) and severity of SUI...
July 2016: Journal of Mid-life Health
https://www.readbyqxmd.com/read/27713797/trained-and-dedicated-staff-appears-to-be-the-main-factor-in-decreasing-anxiety-and-improving-overall-satisfaction-during-urodynamic-testing-a-prospective-randomized-trial
#16
Rose Khavari, Cindy Gu, Anastasia C Tran, Robert Chan
INTRODUCTION: We sought to determine whether listening to patient-selected music during urodynamic study (UDS) reduced pain and anxiety while increasing overall patient satisfaction and willingness to repeat the procedure. METHODS: Fifty-one (51) patients who underwent UDS from March to July 2014 were randomized into two groups: Group 1 with patient-selected music during the procedure (n=27) and Group 2 without music (n=24). Standard multichannel filling cystometry was performed...
May 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27709382/effect-of-doxazosin-on-autonomic-nervous-control-and-urodynamics-of-rat-urinary-bladder-during-modeled-infravesical-obstruction
#17
V I Kirpatovskii, I S Mudraya, S V Revenko, A Yu Bablumyan, N K Adamyan, V P Ivanov
The therapeutic effect of doxazosin (40 μg/kg/day over one month) on urinary bladder was examined in female rats with modeled chronic infravesical obstruction (IVO) produced by graduated mechanical constriction of the proximal urethral segment. In one month, IVO induced a pronounced vesical hypertrophy both in treated and untreated rats that manifested in increased bladder weight and capacity, the latter increment being pronouncedly greater in treated rats. In untreated IVO rats, infusion cystometry revealed elevated basal intravesical pressure of void bladder P0, markedly increased maximal (premicturitional) pressure Pmax, and increased amplitude of spontaneous oscillations of intravesical pressure ΔPdet in filled bladder...
September 2016: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/27706014/typical-value-ranges-and-typical-signal-patterns-in-the-initial-cough-in-patients-with-neurogenic-bladder-quality-control-in-urodynamic-studies
#18
Tianji Lu, Limin Liao
PURPOSE: The goal of this study was to establish typical value ranges (TVRs) and to analyze typical signal patterns (TSPs) of the initial cough (cough before bladder filling) for quality control in urodynamic studies. METHODS: A total of 539 urodynamic traces from patients with neurogenic bladder obtained over the course of a year were retrospectively reviewed. The TVRs for cough amplitude in measurements of the intravesical pressure (Pves), abdominal pressure (Pabd), and detrusor pressure (Pdet) during the initial cough were established...
September 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/27676891/voiding-dysfunction-and-cerebellum-stroke-in-a-child-case-report
#19
Thibault Pasquet, Eva Chinier, Julien Durigneux, Amélie Anselmetti, Chantal Tessiot, Marion Beaumesnil, Matthieu Delion, Mickael Dinomais
OBJECTIVE: We present a case of voiding symptoms after an isolated hemorrhagic cerebellum stroke of the right cerebellum hemisphere and the vermis in a 15 year-old boy with no medical history. The aim of this case is to show existence of a link between cerebellum and micturition. OBSERVATIONS: Following the stroke, the patient described dysuria, confirmed by uroflowmetry, with significants post-voiding residuals. Cystometry showed no detrusor contraction and urethral profilometry showed an increase in sphincter tone...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676696/nerve-growth-factor-release-from-the-urothelium-increases-via-activation-of-bladder-c-fiber-in-rats-with-cerebral-infarction
#20
Ryusei Yokokawa, Hironobu Akino, Hideaki Ito, Xinmin Zha, Osamu Yokoyama
AIMS: There are some reports that bladder C-fibers are partially involved in detrusor overactivity in patients with brain lesions. We investigated the contribution of bladder C-fiber to decreased bladder capacity in rats with cerebral infarction. METHODS: Cerebral infarction was induced under halothane anesthesia by left middle cerebral artery occlusion with 4-0 nylon thread in female Sprague-Dawley rats. Intramural amounts of ATP and prostaglandin E2 , in vivo and in vitro ATP, NGF, and prostaglandin E2 release from the distended bladder urothelium, and changes in mRNA expressions of sensor molecules and receptors were monitored 6 h after the occlusion...
September 27, 2016: Neurourology and Urodynamics
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