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Ventilation in COPD

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https://www.readbyqxmd.com/read/29321341/exercise-tolerance-and-balance-of-inspiratory-to-expiratory-muscle-strength-in-relation-to-breathing-timing-in-patients-with-chronic-obstructive-pulmonary-disease
#1
Keisuke Miki, Kazuyuki Tsujino, Tatsuya Edahiro, Seigo Kitada, Mari Miki, Kenji Yoshimura, Hiroyuki Kagawa, Yohei Oshitani, Yuko Ohara, Yuki Hosono, Hiroyuki Kurebe, Ryoji Maekura
Little is known about the applicability of respiratory muscle training based on exertional pathophysiological conditions in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to investigate the relationship between breathing timing and exertional responses, as well as whether exertional changes in the inspiratory duty cycle (inspiratory time [Ti]/total time [Ttot]) affect pathophysiological conditions, including respiratory muscles. Methods: Forty-five stable COPD patients (mean age: 71...
January 11, 2018: Journal of Breath Research
https://www.readbyqxmd.com/read/29319542/supplemental-oxygen-in-patients-with-stable-chronic-obstructive-pulmonary-disease-evidence-from-nocturnal-oxygen-treatment-trial-to-long-term-oxygen-treatment-trial
#2
Umur Hatipoğlu, James K Stoller
PURPOSE OF REVIEW: Oxygen therapy was the first treatment shown to prolong life in patients with chronic obstructive pulmonary disease (COPD) and has been joined by lung volume reduction surgery in selected patients with emphysema, smoking cessation, and potentially noninvasive ventilation in chronic hypercapneic respiratory failure. Although there is consensus around the survival-enhancing effect of supplemental oxygen (SupplO2) for patients with chronic severe hypoxemia at rest, the impact of SupplO2 for COPD patients with moderate hypoxemia and exertional desaturation had been less clear...
January 9, 2018: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/29319038/noninvasive-ventilation-neurally-adjusted-ventilator-assist-for-management-of-acute-exacerbation-of-chronic-obstructive-pulmonary-disease
#3
Vijay Hadda, Tajamul Hussain Shah, Karan Madan, Anant Mohan, Gopi C Khilnani, Randeep Guleria
Patient-ventilator asynchrony is common with noninvasive ventilation (NIV) used for management of acute exacerbation of chronic obstructive pulmonary disease (COPD). Neurally adjusted ventilator assist (NAVA) is a mode of ventilatory support which can minimize the patient-ventilator asynchrony. Delivering NIV with NAVA (NIV-NAVA) during acute exacerbation of COPD seems a logical approach and may be useful in reducing patient-ventilator asynchrony. However, there are no published reports which describe the use of NIV-NAVA for management of acute exacerbation of COPD...
January 2018: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/29319037/ventilator-dependent-pulmonary-nocardiosis-in-a-patient-with-chronic-obstructive-pulmonary-disease
#4
Stella Pak, Tarek Mansour, Yan Yatsynovich, Andrew Kobalka
Nocardiosis is a rare infectious disease entity that mostly affects the lungs, brain, or skin of immunocompromised individuals. Recent reports of pulmonary nocardiosis (PN) in patients with chronic obstructive pulmonary disease (COPD) as the only risk factor suggest a possible association between nocardiosis and COPD. Herein, we present a case of ventilator-dependent PN in a patient with a moderate degree of COPD. A high level of suspicion for PN should be maintained when encountered with COPD patients complaining of symptoms of pneumonia and excessive thirst...
January 2018: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/29317845/pyomyositis-in-the-setting-of-complicated-diverticulitis-case-report
#5
James Sun, David Leor Kashan, Jolita Marie Auguste, Akella Chendrasekhar
Pyomyositis is typically thought of as a disease of the tropics. However, it is becoming more prevalent in temperate regions, and may be underdiagnosed. Here, pyomyositis is encountered as a complication of perforated diverticulitis, which has not been previously reported. A 61-year-old Caucasian man initially presented in respiratory distress and was diagnosed with respiratory failure due to COPD exacerbation. The patient was taking high-dose prednisone, 60 mg daily for the past 2 years. Initially, he was afebrile, normotensive, tachycardic to 178 beats/minute and tachypneic to 28 breaths/minute, requiring noninvasive ventilation to maintain oxygenation...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29316273/pilot-project-physiologic-responses-to-a-high-intensity-active-video-game-with-copd-patients-tools-for-home-rehabilitation
#6
Andrée-Anne Parent, Vincent Gosselin-Boucher, Marilyn Houle-Peloquin, Claude Poirier, Alain-Steve Comtois
INTRODUCTION: Chronic Obstructive Pulmonary Disease (COPD) is a respiratory condition that causes a significant deterioration of the quality of life. However, exercise can improve the quality of life for COPD patients and it is for this reason previous study observed the effects of active video games to increase exercise. Using motion capture devices with short bursts of exercise never been tried with COPD patients. OBJECTIVES: The objective was to observe the feasibility of using this device safely and easily with COPD patients...
January 8, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29279363/lack-of-benefit-of-heliox-during-mechanical-ventilation-of-subjects-with-severe-air-flow-obstruction
#7
James W Leatherman, Ramiro Saavedra Romero, Robert S Shapiro
BACKGROUND: The value of heliox (helium-oxygen mixture) for patients with severe air-flow obstruction is uncertain. The purpose of this study was to determine whether heliox could reduce the degree of hyperinflation and hypercapnia in mechanically ventilated patients with severe air-flow obstruction. METHODS: This was a single-center, prospective observational study conducted in a medical ICU of an academic medical center. We assessed the impact of heliox (65-70% helium, 30-35% oxygen) on airway pressures and arterial blood gases of 13 subjects undergoing mechanical ventilation for severe asthma (n = 8) or exacerbation of COPD (n = 5)...
December 26, 2017: Respiratory Care
https://www.readbyqxmd.com/read/29261579/endoscopic-lung-volume-reduction-in-copd-improvements-in-gas-transfer-capacity-are-associated-with-improvements-in-ventilation-and-perfusion-matching
#8
Kelvin Hsu, Jonathan P Williamson, Matthew J Peters, Alvin J Ing
BACKGROUND: Endoscopic lung volume reduction (ELVR) has been shown to improve lung function, quality of life, and exercise tolerance in patients with severe heterogeneous emphysema. Our study aims to determine the effect of ELVR on gas transfer capacity corrected for alveolar volume (KCO) and investigate the relationship between KCO and ventilation and perfusion (VQ) matching. We speculate on possible mechanisms for the observed changes METHODS:: Patients with severe chronic obstructive pulmonary disease were prospectively recruited and underwent unilateral upper lobe ELVR between 2012 and 2014...
January 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29232680/is-outpatient-control-of-long-term-non-invasive-ventilation-feasible-in-chronic-obstructive-pulmonary-disease-patients
#9
Sarah Bettina Schwarz, Jens Callegari, Christine Hamm, Wolfram Windisch, Friederike Sophie Magnet
BACKGROUND: Long-term non-invasive ventilation (NIV) is an established and increasingly used treatment option for patients with chronic hypercapnic chronic obstructive pulmonary disease (COPD). Following inpatient NIV establishment, inpatient control visits regularly occur thereafter. However, it remains unclear whether such control visits can also be performed in an outpatient setting, which, in turn, would reduce costs, patient burden and the complications related to hospitalization...
December 12, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29231586/-effects-of-acupuncture-on-peripheral-skeletal-muscle-exercise-ability-in-patients-with-chronic-obstructive-pulmonary-disease-at-stable-phase
#10
Yan Ge, Hong Yao, Juan Tong, Ying He, Guiyuan Li, Xiang'ao Kong
OBJECTIVE: To explore the effects of acupuncture on improving the peripheral skeletal muscle exercise ability in patients with chronic obstructive pulmonary disease (COPD) at stable phase. METHODS: Forty-four patients were randomly divided into an observation group (24 cases) and a control group (20 cases). Based on regular western medication treatment and aerobic training, acupuncture was used in the observation group and placebo acupuncture was used in the control group...
April 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29228942/multiple-breath-washout-testing-in-adults-with-pulmonary-disease-and-healthy-controls-can-fewer-measurements-eventually-be-more
#11
Frederik Trinkmann, Johannes Götzmann, Daniel Saur, Michele Schroeter, Katharina Roth, Ksenija Stach, Martin Borggrefe, Joachim Saur, Ibrahim Akin, Julia D Michels
BACKGROUND: Multiple breath washout (MBW) became a valuable research tool assessing ventilation heterogeneity. However, routine clinical application still faces several challenges. Deriving MBW parameters from three technically acceptable measurements according to current recommendations prolongs test times. We therefore aimed to evaluate reporting only duplicate measurements in healthy adults and pulmonary disease. METHODS: One hundred and fifty-three subjects prospectively underwent conventional lung function testing and closed-circuit SF6-MBW...
December 11, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29228436/the-effect-of-ventilator-mask-atomization-inhalation-of-ipratropium-bromide-and-budesonide-suspension-liquid-in-the-treatment-of-copd-in-acute-exacerbation-period-on-circulating-levels-of-inflammation-and-prognosis
#12
D-H Jiang, X Wang, L-S Liu, D-D Ji, N Zhang
OBJECTIVE: We investigated the effects of ventilator mask atomization inhalation of ipratropium bromide and budesonide suspension liquid in the treatment of acute exacerbation COPD (AECOPD) on circulating levels of inflammatory factors and prognosis. PATIENTS AND METHODS: A total of 86 cases of patients on ventilator support were randomly divided into control group and observation group with 43 cases each. The control group was administered routine treatment including basic disease treatment, anti-infection, maintenance of a stable internal environment, nutritional support, oxygen inhalation and so on...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29224257/models-of-care-for-non-invasive-ventilation-in-the-acute-copd-comparison-of-three-tertiary-hospitals-act3-study
#13
Kerry Parker, Vara Perikala, Ali Aminazad, Zheng Deng, Brigitte Borg, Catherine Buchan, Jo Toghill, Louis B Irving, Jeremy Goldin, David Charlesworth, Ajay Mahal, Suhith Illesinghe, Matthew T Naughton, Alan Young
BACKGROUND AND OBJECTIVE: Non-invasive ventilation (NIV) improves clinical outcomes in hypercapnic acute exacerbations of COPD (AECOPD), but the optimal model of care remains unknown. METHODS: We conducted a prospective observational non-inferiority study comparing three models of NIV care: general ward (Ward) (1:4 nurse to patient ratio, thrice weekly consultant ward round), a high dependency unit (HDU) (1:2 ratio, twice daily ward round) and an intensive care unit (ICU) (1:1 ratio, twice daily ward round) model in three similar teaching tertiary hospitals...
December 10, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29212083/which-nebulizer-position-should-be-avoided-an-extended-study-of-aerosol-delivery-and-ventilator-performance-during-noninvasive-positive-pressure-ventilation
#14
Yun Peng, Bing Dai, Chun-Xiang Hu, Jia Su, Wei Tan, Hong-Wen Zhao, Jian Kang
BACKGROUND: Research on the effect of nebulizer location on aerosol delivery during noninvasive ventilation has reached inconsistent conclusions. OBJECTIVE: To investigate the effects of nebulizer position on aerosol delivery efficiency and ventilator performance during noninvasive ventilation. METHODS: The Active Servo Lung 5000 respiratory simulation system (ASL5000) was used to simulate a COPD patient. The noninvasive ventilator was set to the spontaneous breathing mode...
December 6, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29208755/home-mechanical-ventilation-a-12-year-population-based-retrospective-cohort-study
#15
Marcus Povitz, Louise Rose, Salimah Z Shariff, Sean Leonard, Blayne Welk, Krista Bray Jenkyn, David J Leasa, Andrea S Gershon
BACKGROUND: Increasing numbers of individuals are being initiated on home mechanical ventilation, including noninvasive (bi-level) and invasive mechanical ventilation delivered via tracheostomy due to chronic respiratory failure to enable symptom management and promote quality of life. Given the high care needs of these individuals, a better understanding of the indications for home mechanical ventilation, and health-care utilization is needed. METHODS: We performed a retrospective cohort study using provincial health administrative data from Ontario, Canada (population ∼13,000,000)...
December 5, 2017: Respiratory Care
https://www.readbyqxmd.com/read/29206052/risk-trajectories-of-readmission-and-death-in-the-first-year-following-hospitalization-for-copd
#16
Peter K Lindenauer, Kumar Dharmarajan, Li Qin, Zhenqui Lin, Andrea S Gershon, Harlan M Krumholz
Rationale Characterizing the dynamic nature of post-hospital risk in COPD is needed to provide counseling and plan clinical services. Objectives To analyze risk of readmission and death among Medicare beneficiaries >=65 years following discharge for COPD, and to determine the association between ventilator support and risk trajectory. Methods We computed daily absolute risks of hospital readmission and death for one year after discharge for COPD, stratified by ventilator support. We determined the time required for risks to decline 50% from maximum daily values after discharge; and for daily risks to plateau...
December 5, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29196698/high-pressure-versus-low-pressure-home-non-invasive-positive-pressure-ventilation-with-built-in-software-in-patients-with-stable-hypercapnic-copd-a-pilot-study
#17
Rongchang Chen, Lili Guan, Weiliang Wu, Xiaoying Li, Xin Chen, Bingpeng Guo, Yating Huo, Jiawen Xu, Yuqiong Yang, Luqian Zhou
High-pressure non-invasive positive pressure ventilation (NPPV) is a new strategy targeted at maximally reducing arterial carbon dioxide. However, high inspiratory positive airway pressure (IPAP) might cause respiratory adverse events likely to diminish the benefit of NPPV. In the setting of ventilatory support, monitoring NPPV efficacy and resolving problems promptly are critical. This study assessed the treatment effect of high and low-pressure NPPV in chronic hypercapnic COPD using home ventilator with built-in software...
December 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29186145/respective-impact-of-implementation-of-prevention-strategies-colonization-with-multiresistant-bacteria-and-antimicrobial-use-on-the-risk-of-early-and-late-onset-vap-an-analysis-of-the-outcomerea-network
#18
Wafa Ibn Saied, Bertrand Souweine, Maité Garrouste-Orgeas, Stéphane Ruckly, Michael Darmon, Sébastien Bailly, Yves Cohen, Elie Azoulay, Carole Schwebel, Aguila Radjou, Hatem Kallel, Christophe Adrie, Anne-Sylvie Dumenil, Laurent Argaud, Guillaume Marcotte, Samir Jamali, Laurent Papazian, Dany Goldgran-Toledano, Lila Bouadma, Jean-Francois Timsit
RATIONALE: The impact of prevention strategies and risk factors for early-onset (EOP) versus late-onset (LOP) ventilator-associated pneumonia (VAP) are still debated. OBJECTIVES: To evaluate, in a multicenter cohort, the risk factors for EOP and LOP, as the evolution of prevention strategies. METHODS: 7,784 patients with mechanical ventilation (MV) for at least 48 hours were selected into the multicenter prospective OUTCOMEREA database (1997-2016)...
2017: PloS One
https://www.readbyqxmd.com/read/29175966/non-invasive-positive-pressure-ventilation-should-be-considered-in-patients-with-copd-and-persistent-hypercapnia-at-least-2-weeks-after-resolution-of-acute-respiratory-failure
#19
COMMENT
https://www.readbyqxmd.com/read/29162728/evaluating-the-value-of-the-respiratory-therapist-where-is-the-evidence-focus-on-the-barnes-jewish-hospital-experience
#20
Marin H Kollef
Currently, >20 million people in the United States have asthma, and approximately 15 million adults have been diagnosed with COPD, with approximately the same number not yet having been diagnosed with this condition. Moreover, the overall burden of respiratory diseases is still increasing, in part due to environmental factors, such as air pollution. At the same time, the number of patients requiring hospitalization as well as the number of individuals admitted to ICUs from emergency departments has been on the rise over the last decade...
December 2017: Respiratory Care
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