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https://www.readbyqxmd.com/read/22047984/estrogen-replacement-therapy-for-idiopathic-outflow-tract-ventricular-arrhythmias-a-potential-therapeutic-approach
#1
Hong Jiang, Xiaorong Hu, Jichun Wang
Idiopathic outflow tract ventricular arrhythmias (IOTVA), including left and right ventricular outflow tract, are dued to cyclic adenosine monophosphate (cAMP)-mediated calcium-dependent delayed after depolarizations. A growing body of evidence suggests that the changes of sex hormone levels and gender differences may affect ventricular repolarization and be associated with the occurrence of ventricular arrhythmias. Recent studies showed that the level of estradiol in the IOTVA male patients decreased significantly and the count of ventricular arrhythmias was significantly negatively correlated with the level of estradiol in male patients with IOTVA...
January 2012: Medical Hypotheses
https://www.readbyqxmd.com/read/21402342/effect-of-oestrogen-replacement-therapy-on-idiopathic-outflow-tract-ventricular-arrhythmias-in-postmenopausal-women
#2
Xiaorong Hu, Jichun Wang, Changwu Xu, Bo He, Zhibing Lu, Hong Jiang
BACKGROUND: Sex hormones and gender differences are associated with the occurrence of ventricular arrhythmias. AIM: To investigate the relationship between sex hormones and idiopathic outflow tract ventricular arrhythmias (IOTVA), and the effect of oestrogen replacement therapy on IOTVA, in postmenopausal female patients. METHODS: Plasma sex hormone concentrations and ventricular arrhythmia counts were estimated in postmenopausal patients with IOTVA and control postmenopausal women...
February 2011: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/19840768/relationship-between-sex-hormones-and-idiopathic-outflow-tract-ventricular-arrhythmias-in-adult-male-patients
#3
Xiaorong Hu, Hong Jiang, Changwu Xu, Xiaoya Zhou, Bo Cui, Zhibing Lu
Sex hormones and gender differences have been reported to be associated with the occurrences of ventricular arrhythmias. This study investigated the relationship between sex hormones and idiopathic outflow tract ventricular arrhythmias (IOTVA) in adult male patients. Serum sex hormonal levels, which include testosterone, estradiol, and progestogen, were measured by using commercially prepared immunoassay kits. The average count of premature ventricular contractions (PVCs) (number/24h) was assessed by 72h electrocardiographic monitoring...
November 2009: Translational Research: the Journal of Laboratory and Clinical Medicine
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