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skin diseases in geriatric population

E Makrantonaki, E Steinhagen-Thiessen, R Nieczaj, C C Zouboulis, R Eckardt
BACKGROUND: Improvement of quality of life in old age and prevention of age-associated diseases have become the main focus of research into aging; however, information regarding the skin health status of geriatric patients still remains sparse. GOAL: To investigate the extent of dermatological diseases in hospitalized geriatric patients, map the most prevalent ones, check for any gender differences and document any correlations with duration of hospitalization and results of geriatric assessments...
June 28, 2016: Zeitschrift Für Gerontologie und Geriatrie
Rashmi Jindal, Akanksha Jain, Samarjit Roy, S D S Rawat, Nancy Bhardwaj
INTRODUCTION: Ageing results in decline of normal functioning in all organ systems including skin. This predisposes the elderly persons to develop various skin ailments. A thorough knowledge of different diseases prevalent in this population in different geographic regions help the health care providers in better health care policy making. AIM: This study was planned to know the common dermatological diseases prevalent in Uttarakhand region of India. MATERIALS AND METHODS: Hospital out patients records maintained in Department of Dermatology, Venereology & Leprosy were analysed and information regarding age, sex and diagnosis of patients were recorded...
March 2016: Journal of Clinical and Diagnostic Research: JCDR
Ryoji Tanei, Yasuko Hasegawa
Atopic dermatitis (AD) in older adults represents a newly defined subgroup of AD. The prevalence of elderly AD is approximately 1-3% among elderly populations in industrialized countries. Elderly patients with AD show some common clinical characteristics, such as a male predominance, a lower incidence of lichenified eczema at the elbow and knee folds, and particular patterns of onset and clinical course. Both immunoglobulin (Ig)E-allergic and non-IgE-allergic types are observed in elderly AD. Elderly patients with IgE-allergic AD show high rates of positivity for specific IgE antibodies against house dust mites, associations with IgE allergic and asthmatic complications, histopathological features with a predominance of IgE-mediated allergic inflammation in the lesional skin, and a significantly lower incidence of malignancy as compared with control subjects...
March 2016: Geriatrics & Gerontology International
Philippe Humbert, Brigitte Dréno, Jean Krutmann, Thomas Anton Luger, Raoul Triller, Sylvie Meaume, Sophie Seité
The increasingly aged population worldwide means more people are living with chronic diseases, reduced autonomy, and taking various medications. Health professionals should take these into consideration when managing dermatological problems in elderly patients. Accordingly, current research is investigating the dermatological problems associated with the loss of cutaneous function with age. As cell renewal slows, the physical and chemical barrier function declines, cutaneous permeability increases, and the skin becomes increasingly vulnerable to external factors...
2016: Clinical Interventions in Aging
Muhterem Polat, Mustafa N İlhan
The geriatric population is continuously growing, which leads to more aged patients being admitted to dermatology clinics. The aim of this study is to determine the dermatological complaints of the elderly attending a dermatology outpatient clinic. All of the patients aged 65 years and older admitted to our dermatology outpatient clinic over a 1-year period were included. Patients were divided into 2 groups according to their ages as group I (65-74 years) and group II (≥75 years). The patients were asked about their dermatologic complaints...
2015: Acta Dermatovenerologica Croatica: ADC
Pulak R Manna, Cloyce L Stetson, Andrzej T Slominski, Kevin Pruitt
Steroid hormones are an important class of regulatory molecules that are synthesized in steroidogenic cells of the adrenal, ovary, testis, placenta, brain, and skin, and influence a spectrum of developmental and physiological processes. The steroidogenic acute regulatory protein (STAR) predominantly mediates the rate-limiting step in steroid biosynthesis, i.e., the transport of the substrate of all steroid hormones, cholesterol, from the outer to the inner mitochondrial membrane. At the inner membrane, cytochrome P450 cholesterol side chain cleavage enzyme cleaves the cholesterol side chain to form the first steroid, pregnenolone, which is converted by a series of enzymes to various steroid hormones in specific tissues...
January 2016: Endocrine
Radomir Reszke, Dorota Pełka, Angela Walasek, Zbigniew Machaj, Adam Reich
BACKGROUND: Skin problems in the elderly population have rarely been the subject of scientific research. OBJECTIVES: The present study aimed to determine the prevalences of the most common dermatological conditions in elderly subjects and to investigate their associations with systemic diseases. METHODS: The study involved a group of 198 consecutive patients aged ≥ 65 years who were admitted to the Departments of Dermatology and Geriatrics at the study institution...
September 2015: International Journal of Dermatology
Amit S Chitnis, Katherine Robsky, Gisela F Schecter, Janice Westenhouse, Pennan M Barry
OBJECTIVES: To examine trends in tuberculosis (TB) incidence and to compare demographic and clinical characteristics of nursing home (NH) residents and community-dwelling older adults. DESIGN: Prospective TB surveillance. SETTING: TB cases reported in California from 2000 to 2009. PARTICIPANTS: TB patients aged 65 and older. MEASUREMENTS: Trends in TB incidence per 100,000 population were assessed using Poisson regression...
June 2015: Journal of the American Geriatrics Society
Franca Marangoni, Giovanni Corsello, Claudio Cricelli, Nicola Ferrara, Andrea Ghiselli, Lucio Lucchin, Andrea Poli
The relationship between the consumption of meat and health is multifaceted, and it needs to be analyzed in detail, with specific attention to the relevant differences that characterize the effects of the different meat types, as yet considered by only a limited literature. A variable but moderate energy content, highly digestible proteins (with low levels of collagen) of good nutritional quality, unsaturated lipids (mainly found in the skin and easily removed), B-group vitamins (mainly thiamin, vitamin B6, and pantothenic acid), and minerals (like iron, zinc, and copper) make poultry meat a valuable food...
2015: Food & Nutrition Research
Melissa J Danesh, Anne Lynn S Chang
The National Research Council of the National Academies defines elder mistreatment as: (1) intentional actions that cause harm or create serious risk of harm (whether or not harm is intended) to a vulnerable elder by a caregiver or other person who stands in a trust relationship to the elder; or (2) failure by a caregiver to satisfy the elder's basic needs or to protect the elder from harm. Estimates of the prevalence of elder abuse have ranged from 2.2% to 18.4%. Dermatologists are uniquely positioned to identify and manage suspected cases of elder abuse given their expertise in distinguishing skin lesions of abuse from organic medical disease and their patient populations with strong elderly representation...
August 2015: Journal of the American Academy of Dermatology
Pragya A Nair, Rita Vora
INTRODUCTION: Aging population is susceptible to many cutaneous and systemic diseases, simultaneously leading to impairment of quality of life in them. AIM: To know the association of dermatosis and systemic diseases in geriatric age group. MATERIALS AND METHODS: A retrospective study was carried on patients above 60 years of age who visited the Dermatology OPD at rural tertiary care centre from June 2009 to May 2010. Patients were assessed on a prescribed 30 point proforma...
January 2015: Journal of Family Medicine and Primary Care
J A Gerdin, S P McDonough, R Reisman, J Scarlett
The authors reviewed the case circumstances, population characteristics, gross, and histopathologic findings in 40 cases of emaciated dogs with a suspected diagnosis of starvation. The dogs' estimated age ranged from 3 months to geriatric. Nineteen breeds were represented, including small-breed (n = 11), large-breed (n = 13), and pit bull-type (n = 16) dogs. The median body condition score was 1 out of 9 (Purina scale). Various diseases were identified as the cause of death in 7 dogs, while the cause of death in the other 33 dogs was starvation due to exogenous causes (SEC)...
September 2016: Veterinary Pathology
David G Greenhalgh
Aging has significant effects on the healing ability of the geriatric population. When the elderly suffer injuries, they have a decreased metabolic reserve to handle the stress required to recover. Diseases of the elderly, such as malnutrition, diabetes mellitus, treatment of malignancies, and vascular disease, all impair tissue repair. The geriatric population is more prone to pressure ulcers, venous stasis ulcers, and other chronic wounds. This review discusses how changes in the elderly lead to impaired healing or chronic wounds...
February 2015: Surgical Clinics of North America
Katherine L Caretti, Darius R Mehregan, David A Mehregan
BACKGROUND: In the USA, the geriatric population, almost 12% of which will be comprised of African-Americans, is expected to exceed 88 million by 2050. Data on dermatologic conditions in elderly African-Americans are deficient. OBJECTIVES: This study aimed to identify prevalences of self-reported skin disease and skin-related concerns in elderly African-Americans, and to assess participants' perceptions of skin disease and awareness of skin cancer. METHODS: Elderly African-Americans were recruited into a cross-sectional study and asked to complete a 17-item questionnaire...
September 2015: International Journal of Dermatology
J Wohlrab, K Hilpert, A Wohlrab
The change in the population's age structure in most industrial countries, as in Germany, requires geriatric medicine to play an increasingly important role. Dermatology also has to meet the new challenges by expert discussion and ethical considerations. The physiological aging process is influenced by intrinsic and extrinsic factors and causes a variety of morphological and functional alterations in the skin. Those alterations are the cause for an increasing prevalence of many dermatoses. Infections, wound healing disorders, inflammatory diseases, tumors and associated paraneoplastic syndromes are of particular importance...
October 2014: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
David Melzer, Behrooz Tavakoly, Rachel E Winder, Jane A H Masoli, William E Henley, Alessandro Ble, Suzanne H Richards
BACKGROUND: the oldest old (85+) pose complex medical challenges. Both underdiagnosis and overdiagnosis are claimed in this group. OBJECTIVE: to estimate diagnosis, prescribing and hospital admission prevalence from 2003/4 to 2011/12, to monitor trends in medicalisation. DESIGN AND SETTING: observational study of Clinical Practice Research Datalink (CPRD) electronic medical records from general practice populations (eligible; n = 27,109) with oversampling of the oldest old...
January 2015: Age and Ageing
Albert Nienhaus, Anja Schablon, Alexandra M Preisser, Felix C Ringshausen, Roland Diel
INTRODUCTION: Despite the decline of tuberculosis in the population at large, healthcare workers (HCW) are still at risk of infection. METHODS: In a narrative review the TB risk in HCW and preventive measures are described, with the focus on epidemiology and Occupational Safety and Health (OSH) regulations in Germany. RESULTS: There is an increased risk of infection not only in pneumology and laboratories with regular contact with tuberculosis patients or infectious materials...
2014: Journal of Occupational Medicine and Toxicology
P Follana, J Barrière, E Chamorey, R Largillier, B Dadone, V Mari, J M Hannoun-Levi, M Marcy, B Flipo, J-M Ferrero
BACKGROUND: Elderly patients with metastatic breast cancer have a prognosis and outcome that may be dependent on a host of factors. PATIENTS AND METHODS: We retrospectively analyzed 401 female breast cancer patients who developed metastatic disease after the age of 70 years in order to define potential prognostic factors for specific survival at the time of first recurrence. RESULTS: With a median follow-up of 60 months from the time of recurrence, the median specific survival was 21...
2014: Oncology
Alexander M Kulminski, Konstantin G Arbeev, Irina Culminskaya, Liubov Arbeeva, Svetlana V Ukraintseva, Eric Stallard, Kaare Christensen, Nicole Schupf, Michael A Province, Anatoli I Yashin
Enduring interest in the Apolipoprotein E (ApoE) polymorphism is ensured by its evolutionary-driven uniqueness in humans and its prominent role in geriatrics and gerontology. We use large samples of longitudinally followed populations from the Framingham Heart Study (FHS) original and offspring cohorts and the Long Life Family Study (LLFS) to investigate gender-specific effects of the ApoE4 allele on human survival in a wide range of ages from midlife to extreme old ages, and the sensitivity of these effects to cardiovascular disease (CVD), cancer, and neurodegenerative disorders (ND)...
January 2014: PLoS Genetics
Eun Kyung Kim, Hyung Ok Kim, Young Min Park, Chul Jong Park, Dong Su Yu, Jun Young Lee
BACKGROUND: Although rarely life threatening, dermatological diseases may have a considerable influence on a patient's quality of life and psychological well-being. As with morbidity and mental distress from other chronic diseases, a skin disorder can be the one of the main causes of depression in the geriatric population. OBJECTIVE: To determine the prevalence of depression in elderly patients with dermatological disease in Korea and to identify factors associated with depression...
August 2013: Annals of Dermatology
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