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https://www.readbyqxmd.com/read/28538089/central-hematocrit-levels-in-fetal-malnourished-term-infants
#1
Kerem Ertaş, Özgül Salihoğlu, Emrah Can, Sami Hatipoğlu, Şahin Hamilçikan
BACKROUND: Fetal malnutrition is especially important for common chronic diseases in adult life. They could potentially be prevented by achieving optimal fetal nutrition. OBJECTIVE: The aim of this study was to investigate hematocrit levels of malnourished, term, appropriate for gestational age (AGA) neonates. SUBJECTS AND METHODS: A total of 80 AGA neonates (between 10% and 90% percentiles interval according to birth week), born with spontaneous vaginal delivery between 37 and 42 weeks of gestation, detected by both last menstrual period and ultrasonography measurements, were included in the study...
May 23, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28533458/how-camouflage-works
#2
REVIEW
Sami Merilaita, Nicholas E Scott-Samuel, Innes C Cuthill
For camouflage to succeed, an individual has to pass undetected, unrecognized or untargeted, and hence it is the processing of visual information that needs to be deceived. Camouflage is therefore an adaptation to the perception and cognitive mechanisms of another animal. Although this has been acknowledged for a long time, there has been no unitary account of the link between visual perception and camouflage. Viewing camouflage as a suite of adaptations to reduce the signal-to-noise ratio provides the necessary common framework...
July 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28532324/non-diagnostic-based-approaches-to-helping-children-who-could-be-labelled-adhd-and-their-families
#3
Sami Timimi
Mental health services are not always good for you. There are some troubling facts to confront such as the increase in the use of diagnostic based approaches and psychotropic medications for children and young people being associated with poorer rather than better outcomes. In this article I will outline some of the evidence around outcome as a result of treatment for young people diagnosed with attention deficit hyperactivity disorder (ADHD) and for those who are prescribed long-term stimulants. I will then discuss clinical approaches that move beyond a focus on symptom management that diagnostic paradigms encourage...
June 2017: International Journal of Qualitative Studies on Health and Well-being
https://www.readbyqxmd.com/read/28531866/bilateral-peritonsillar-abscess-a-case-report-and-pertinent-literature-review
#4
Ibrahim AlAwadh, Turki Aldrees, Saleh AlQaryan, Sami Alharethy, Hassan AlShehri
INTRODUCTION: The peritonsillar space is defined as the area between the palatine tonsillar capsule medially and the superior pharyngeal constrictor muscle laterally. Unilateral peritonsillar abscess (PTA) is more common than the bilateral condition. To the best of our knowledge, only 13 cases of bilateral PTA have been reported worldwide; this is the first case reported from Saudi Arabia. PRESENTATION OF CASE: We present a case involving a 16-year-old boy who presented to the emergency department with a5-day history of sore throat, dysphagia, trismus, drooling, and a muffled "hot-potato" voice, but with no symptoms of airway compromise...
May 15, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28531273/phenotypes-of-atopic-dermatitis-depending-on-the-timing-of-onset-and-progression-in-childhood
#5
Caroline Roduit, Remo Frei, Martin Depner, Anne M Karvonen, Harald Renz, Charlotte Braun-Fahrländer, Elisabeth Schmausser-Hechfellner, Juha Pekkanen, Josef Riedler, Jean-Charles Dalphin, Erika von Mutius, Roger Pascal Lauener, Anne Hyvärinen, Pirkka Kirjavainen, Sami Remes, Marjut Roponen, Marie-Laure Dalphin, Vincent Kaulek, Markus Ege, Jon Genuneit, Sabina Illi, Micahel Kabesch, Bianca Schaub, Petra Ina Pfefferle, Gert Doekes
Importance: Atopic dermatitis is an inflammatory, pruritic skin disease that often occurs in early infancy with a chronic course. However, a specific description of subtypes of atopic dermatitis depending on the timing of onset and progression of the disease in childhood is lacking. Objective: To identify different phenotypes of atopic dermatitis using a definition based on symptoms before age 6 years and to determine whether some subtypes are more at risk for developing other allergic diseases...
May 22, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28531192/overexpression-of-the-essential-sis1-chaperone-reduces-tdp-43-effects-on-toxicity-and-proteolysis
#6
Sei-Kyoung Park, Joo Y Hong, Fatih Arslan, Vydehi Kanneganti, Basant Patel, Alex Tietsort, Elizabeth M H Tank, Xingli Li, Sami J Barmada, Susan W Liebman
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by selective loss of motor neurons with inclusions frequently containing the RNA/DNA binding protein TDP-43. Using a yeast model of ALS exhibiting TDP-43 dependent toxicity, we now show that TDP-43 overexpression dramatically alters cell shape and reduces ubiquitin dependent proteolysis of a reporter construct. Furthermore, we show that an excess of the Hsp40 chaperone, Sis1, reduced TDP-43's effect on toxicity, cell shape and proteolysis...
May 22, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28531089/au-nanoparticle-decorated-silicon-pyramids-for-plasmon-enhanced-hot-electron-near-infrared-photodetection
#7
Zhiyang Qi, Yusheng Zhai, Long Wen, Qilong Wang, Qin Chen, Sami Iqbal, Guangdian Chen, Ji Xu, Yan Tu
Heterojunction between metal and silicon (Si) is an attractive route to extend the response of Si-based photodiodes into the near-infrared (NIR) region, so-called Schottky barrier diodes. Photons absorbed into a metallic nanostructure excite the surface plasmon resonances (SPRs), which can be damped non-radiatively through the creation of hot electrons. Unfortunately, quantum efficiency of hot electron detectors remains low due to low optical absorption and poor electron injection efficiency. In this study, we propose an efficient and low-cost plasmonic hot electron NIR photodetector based on Au nanoparticle (Au NP)-decorated Si pyramid Schottky junction...
May 22, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28530773/efficiency-of-instant-messaging-applications-in-coordination-of-emergency-calls-for-combat-injuries-a-pilot-study
#8
Sami Eksert, Mehmet Burak Aşık, Sinan Akay, Kenan Keklikçi, Fevzi Nuri Aydın, Mehmet Çoban, Ali Kantemir, Onur Güngör, Beyazıt Garip, Mustafa Suphi Turgut, Kenan Olcay
BACKGROUND: Coordination of an emergency response team is an important determinant of prompt treatment for combat injuries in hospitals. The authors hypothesized that instant messaging applications for smartphones could be appropriate tools for notifying emergency response team members. The objective of this study was to investigate the efficiency of a commercial instant messaging application (WhatsApp, Mountain View, CA) as a communication tool for the emergency team in a level-I trauma center...
May 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28528146/prognostic-value-of-coronary-ct-angiography-with-selective-pet-perfusion-imaging-in-coronary-artery-disease
#9
Teemu Maaniitty, Iida Stenström, Jeroen J Bax, Valtteri Uusitalo, Heikki Ukkonen, Sami Kajander, Maija Mäki, Antti Saraste, Juhani Knuuti
OBJECTIVES: The purpose of this study was to evaluate the prognostic value of sequential hybrid imaging strategy in which positron emission tomography (PET) perfusion imaging is performed selectively in patients with suspected obstructive coronary artery disease (CAD) on coronary computed tomography angiography (CTA). BACKGROUND: Coronary CTA is an accurate diagnostic test for excluding obstructive CAD. However, the positive predictive value is suboptimal. METHODS: We investigated 864 consecutive symptomatic patients with intermediate probability of CAD who adhered to the sequential imaging approach...
May 15, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28527632/cerium-oxide-nanoparticles-could-ameliorate-behavioral-and-neurochemical-impairments-in-6-hydroxydopamine-induced-parkinson-s-disease-in-rats
#10
Maha A Hegazy, Hala M Maklad, Doaa M Samy, Doaa A Abdelmonsif, Bassma M El Sabaa, Fatma Y Elnozahy
BACKGROUND: Cerium oxide nanoparticles (CeO2NPs) showed promising effects in neurodegenerative diseases including some animal models of Parkinsonism. However, the implication of CeO2NPs in 6-hydroxydopamine (6-OHDA) induced Parkinsonism remains to be investigated. AIM: This study was designed to assess whether CeO2NPs treatment could alleviate neurobehavioral and neurobiochemical deficits in 6-OHDA induced neurotoxicity in rats. MATERIAL AND METHODS: 50 rats received left intrastriatal (IS) injection of either saline (control, n = 10) or 6-OHDA (n = 40)...
May 17, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28527321/short-term-exposure-to-gold-nanoparticle-suspension-impairs-swimming-behavior-in-a-widespread-calanoid-copepod
#11
François-Gaël Michalec, Markus Holzner, Alexandre Barras, Anne-Sophie Lacoste, Loïc Brunet, Jae-Seong Lee, Christian Slomianny, Rabah Boukherroub, Sami Souissi
Calanoid copepods play an important role in the functioning of marine and brackish ecosystems. Information is scarce on the behavioral toxicity of engineered nanoparticles to these abundant planktonic organisms. We assessed the effects of short-term exposure to nonfunctionalized gold nanoparticles on the swimming behavior of the widespread estuarine copepod Eurytemora affinis. By means of three-dimensional particle tracking velocimetry, we reconstructed the trajectories of males, ovigerous and non-ovigerous females...
May 17, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28526315/does-educating-nurses-with-ventilator-associated-pneumonia-prevention-guidelines-improve-their-compliance
#12
Sami M Aloush
BACKGROUND: This study aimed to compare the compliance with ventilator-associated pneumonia (VAP)-prevention guidelines between nurses who underwent an intensive educational program and those who did not, and to investigate other factors that influence nurses' compliance. METHOD: A 2-group posttest design was used to examine the effect of the VAP-prevention guidelines education on nurses' compliance. Participants were randomly assigned to experimental and control groups...
May 16, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28525845/novel-amidino-substituted-benzimidazole-and-benzothiazole-benzo-b-thieno-2-carboxamides-exert-strong-antiproliferative-and-dna-binding-properties
#13
Maja Cindrić, Samy Jambon, Anja Harej, Sabine Depauw, Marie-Hélène David-Cordonnier, Sandra Kraljević Pavelić, Grace Karminski-Zamola, Marijana Hranjec
Within this manuscript design, synthesis of novel 2-imidazolinyl substituted benzo[b]thieno-2-carboxamides bearing either benzimidazole or benzothiazole subunit and biological activity are presented and described. The antiproliferative activities were assessed in vitro on a panel of human cancer cell lines. Tested compounds showed moderate activity while cytotoxicity on normal fibroblasts was lower in comparison with 5-fluorouracile. The variations of 2-imidazolinyl substituent at heteroaromatic subunits in different positions led to different cytotoxic properties...
May 4, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28524084/bordetella-holmesii-lipid-a-structures-and-corresponding-genomic-sequences-comparison-in-three-clinical-isolates-and-the-reference-strain-atcc-51541
#14
Valérie Bouchez, Sami AlBitar-Nehmé, Alexey Novikov, Nicole Guiso, Martine Caroff
Bordetella holmesii can cause invasive infections but can also be isolated from the respiratory tract of patients with whooping-cough like symptoms. For the first time, we describe the lipid A structure of B. holmesii reference strain ATCC 51541 (alias NCTC12912 or CIP104394) and those of three French B. holmesii clinical isolates originating from blood (Bho1) or from respiratory samples (FR4020 and FR4101). They were investigated using chemical analyses, gas chromatography-mass spectrometry (GC-MS), and matrix-assisted laser desorption ionization-mass spectrometry (MALDI-MS)...
May 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28522367/qrs-t-wave-and-calcium-alternans-in-a-type-i-diabetic-mouse-model-for-spontaneous-post-myocardial-infarction-ventricular-tachycardia-a-mechanism-for-the-antiarrhythmic-effect-of-statins
#15
Hongwei Jin, Charles M Welzig, Mark Aronovitz, Farzad Noubary, Robert Blanton, Bo Wang, Mohammad Rajab, Alfred Albano, Mark S Link, Sami F Noujaim, Ho-Jin Park, Jonas B Galper
BACKGROUND: The incidence of sudden arrhythmic death is markedly increased in diabetics. OBJECTIVE: Develop a mouse model for Post MI VT in the diabetic heart and determine the mechanism of an antiarrhythmic effect of statins. METHODS: EKG transmitters were implanted in wild type (WT), placebo and pravastatin treated Type I diabetic Akita mice, MIs induced by coronary ligation, Ca(2+) transients studied by optical mapping, Ca(2+) transients and sparks in left VM (VM) by the Ionoptix system and confocal microscopy...
May 15, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28520827/surgical-outcomes-of-bony-batten-grafting-to-correct-caudal-septal-deviation-in-septoplasty
#16
Do-Youn Kim, Sung Hoon Nam, Sami E Alharethy, Yong Ju Jang
Improtance: Correction of caudal septal deviation with a batten graft has been popularized recently. However, few reports have documented the surgical outcomes of this technique, especially the use of bony batten grafts in septoplasty. Objective: To evaluate the surgical outcomes of bony batten grafting for the management of caudal septal deviation in endonasal septoplasty. Design, Setting, and Participants: This retrospective cohort study evaluates the medical records of 141 patients with caudal septal deviation who underwent septoplasty using bony batten grafts from September 1, 2011, through February 29, 2016, at a tertiary referral hospital...
May 18, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28518040/highly-pathogenic-avian-influenza-virus-h5n8-clade-2-3-4-4-infection-in-migratory-birds-egypt
#17
Abdullah A Selim, Ahmed M Erfan, Naglaa Hagag, Ali Zanaty, Abdel-Hafez Samir, Mohamed Samy, Ahmed Abdelhalim, Abdel-Satar A Arafa, Mohamed A Soliman, Momtaz Shaheen, Essam M Ibraheem, Ibrahim Mahrous, Mohamed K Hassan, Mahmoud M Naguib
We isolated highly pathogenic avian influenza virus (H5N8) of clade 2.3.4.4 from the common coot (Fulica atra) in Egypt, documenting its introduction into Africa through migratory birds. This virus has a close genetic relationship with subtype H5N8 viruses circulating in Europe. Enhanced surveillance to detect newly emerging viruses is warranted.
June 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28515853/qt-prolongation-is-associated-with-increased-mortality-in-end-stage-liver-disease
#18
Sun Moon Kim, Bennet George, Diego Alcivar-Franco, Charles L Campbell, Richard Charnigo, Brian Delisle, Jonathan Hundley, Yousef Darrat, Gustavo Morales, Samy-Claude Elayi, Alison L Bailey
AIM: To determine the prevalence of QT prolongation in a large series of end stage liver disease (ESLD) patients and its association to clinical variables and mortality. METHODS: The QT interval was measured and corrected for heart rate for each patient, with a prolonged QT cutoff defined as QT > 450 ms for males and QT > 470 ms for females. Multiple clinical variables were evaluated including sex, age, serum sodium, international normalized ratio, creatinine, total bilirubin, beta-blocker use, Model for End-Stage Liver Disease (MELD), MELD-Na, and etiology of liver disease...
April 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28515636/optic-cup-segmentation-type-ii-fuzzy-thresholding-approach-and-blood-vessel-extraction
#19
Ahmed Almazroa, Sami Alodhayb, Kaamran Raahemifar, Vasudevan Lakshminarayanan
We introduce here a new technique for segmenting optic cup using two-dimensional fundus images. Cup segmentation is the most challenging part of image processing of the optic nerve head due to the complexity of its structure. Using the blood vessels to segment the cup is important. Here, we report on blood vessel extraction using first a top-hat transform and Otsu's segmentation function to detect the curves in the blood vessels (kinks) which indicate the cup boundary. This was followed by an interval type-II fuzzy entropy procedure...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28513976/gingerenone-a-attenuates-monocyte-endothelial-adhesion-via-suppression-of-i-kappa-b-kinase-phosphorylation
#20
Hee Joo Kim, Joe Eun Son, Jae Hwan Kim, Charles C Lee, Hee Yang, Soonham Sami Yaghmoor, Youssri Ahmed, Jehad Mustafa Yousef, Khalid Omer Abualnaja, Abdulrahman Labeed Al-Malki, Taha Abdullah Kumosani, Jung Han Yoon Park, Chang Yong Lee, Jong-Eun Kim, Ki Won Lee
During the early stages of atherosclerosis, monocytes bind and migrate into the endothelial layer, promoting inflammation within the aorta. In order to prevent the development of atherosclerosis, it is critical to inhibit such inflammation. The therapeutic effects of ginger have been investigated in several models of cardiovascular disease. However, although a number of previous studies have focused on specific compounds, the mechanisms of action responsible remain unclear. Here, we investigated five major compounds present in ginger, and observed that gingerenone A exhibited the strongest inhibitory effects against tumor necrosis factor (TNF)- α and lipopolysaccharide (LPS) induced monocyte-endothelial adhesion...
May 17, 2017: Journal of Cellular Biochemistry
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