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REVIEW
Aman Goyal, Laveeza Fatima, Fiza Mushtaq, Muhammad Daoud Tariq, Aemen Kamran, Amir Humza Sohail, Zainali Chunawala, Samia Aziz Sulaiman, Abhigan Babu Shrestha, Abu Baker Sheikh, Agastya D Belur
Endovascular aortic repair is an emerging novel intervention for the management of abdominal aortic aneurysms. It is crucial to compare the effectiveness of different access sites, such as transfemoral access (TFA) and upper extremity access (UEA). An electronic literature search was conducted using PubMed, EMBASE, and Google Scholar databases. The primary endpoint was the incidence of stroke/transient ischemic attack (TIA), while the secondary endpoints included technical success, access-site complications, mortality, myocardial infarction (MI), spinal cord ischemia, among others...
April 8, 2024: Catheterization and Cardiovascular Interventions
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JOURNAL ARTICLE
Asma Sriha Belguith, Rim Klii, Hela Abroug, Walid Bouali, Jihen Chelly, Sondes Arfa, Chokri Chouchen, Mehdi Hasnaoui, Imen Chaabane, Yosra Soua, Soumaya Bouchareb, Mohamed Amine Mosrati, Maroua Bousaid, Nader Slama, Rania Kaddoussi, Hassen Ibn Haj Amor, Maher Tka, Hajer Ben Brahim, Afifa Abdelkefi, Olfa Harzallah, Sourour Ncibi, Samia Grira, Jnaina Kooli, Mouna Ouaz, Maha Ben Mansour, Sonia Zaied, Mejdi Ben Massoud, Ikram Chamtouri, Tarak Kellil, Mohamed Ben Khalifa, Ghassen Belkahla, Nabil Dammak, Hazem Ben Ghozlen, Rachida Laamiri, Aymen Manser, Yassine Binous, Fadia Boubaker, Wafa Ben Alaya, Bilel Ben Amor, Arwa Gueddiche, Mohamed Hichem Loghmari, Haifa Bouchahda, Khouloud Marzouk, Wafa Marrakchi, Adel Sekma, Sarra Sassi, Emira Sghaier, Ines Rassas, Marouane Hayouni, Asma Khedher, Dorra Oualha, Amine Kalai, Houda Migaou, Aymen Haj Salah, Mouna Sghir, Hayet Ben Hmida, Mouna Hammouda, Kais Maamri, Mouna Aissi, Amel Korbi, Sameh Mbarek, Imen Khairallah, Amina Wardani, Nesrine Jammali, Zohra Chadli, Asma Guedria, Jamel Saad, Amina Ben Salem, Hayfa Hachfi, Mahbouba Jguirim, Oussama Jaoued, Souheil Elatrous, Manel Lahmar, Lamia Besbes Wannes, Ahmed Zrig, Charfeddine Amri
UNLABELLED: Introduction-Aim: The third cycle of medical studies (TCMS) lasts 3 years for the specialty of family medicine (FM) in Tunisia. The members of the FM committee of the Faculty of Medicine of Monastir (FMM) aimed to detail the learning objectives (LO) of residents in FM. METHOD: We used the Delphi method in 2 rounds including a group of experts called FM Learning Objectives Writing Group (FMLOWG) at the FMM. The FMLOWG included 74 university hospital physicians and FM internship supervisors...
November 5, 2023: La Tunisie Médicale
#3
JOURNAL ARTICLE
Virtual Assistants' Response to Queries About Nicotine Replacement Therapy: A Mixed-Method Analysis.
Samia Amin, Kylie Uyeda, Ian Pagano, Kayzel R Tabangcura, Rachel Taketa, Crissy Terawaki Kawamoto, Pallav Pokhrel
This study focused on investigating the potential of Artificial Intelligent-powered Virtual Assistants (VAs) such as Amazon Alexa, Apple Siri, and Google Assistant as tools to help individuals seeking information about Nicotine Replacement Treatment (NRT) for smoking cessation. The researchers asked 40 NRT-related questions to each of the 3 VAs and evaluated the responses for voice recognition. The study used a cross-sectional mixed-method design with a total sample size of 360 responses. Inter-rater reliability and differences between VAs' responses were examined by SAS software, and qualitative assessments were conducted using NVivo software...
February 26, 2024: Evaluation & the Health Professions
#4
JOURNAL ARTICLE
Célia Dupain, Tom Gutman, Elodie Girard, Choumouss Kamoun, Grégoire Marret, Zahra Castel-Ajgal, Marie-Paule Sablin, Cindy Neuzillet, Edith Borcoman, Ségolène Hescot, Céline Callens, Olfa Trabelsi-Grati, Samia Melaabi, Roseline Vibert, Samantha Antonio, Coralie Franck, Michèle Galut, Isabelle Guillou, Maral Halladjian, Yves Allory, Joanna Cyrta, Julien Romejon, Eleonore Frouin, Dominique Stoppa-Lyonnet, Jennifer Wong, Christophe Le Tourneau, Ivan Bièche, Nicolas Servant, Maud Kamal, Julien Masliah-Planchon
BACKGROUND: High tumor mutational burden (TMB) was reported to predict the efficacy of immune checkpoint inhibitors (ICIs). Pembrolizumab, an anti-PD-1, received FDA-approval for the treatment of unresectable/metastatic tumors with high TMB as determined by the FoundationOne®CDx test. It remains to be determined how TMB can also be calculated using other tests. RESULTS: FFPE/frozen tumor samples from various origins were sequenced in the frame of the Institut Curie (IC) Molecular Tumor Board using an in-house next-generation sequencing (NGS) panel...
February 20, 2024: BMC Biology
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JOURNAL ARTICLE
Reham Magdy Mohammed AbdElsalam, Samia ElHusseini Abd-ElMageed ElKholy
BACKGROUND: With the ageing population increasing worldwide, identifying effective approaches to counteract cognitive decline becomes significant for maintaining cognitive health and quality of life in older adults. The lack of cognitive activity accelerates age cognitive decline. Cognitive stimulation interventions can maintain older adults' cognitive reserve, enhance their feelings of happiness, and potentially improve their psychosocial wellbeing. AIM: This study aimed to determine the impact of Cognitive Stimulation Intervention on older adults' cognitive function, cognitive self-efficacy, and sense of happiness...
February 14, 2024: Geriatric Nursing
#6
Samia Shuja, Sadia Rauf
Twin pregnancy with one fetus and one complete mole falls amongst extremely rare obstetric situations. The spectrum of complications associated with it is wide. Once diagnosed, the choice between continuation and termination of pregnancy depends upon couple's preference and readiness to accept possible complications. Key to success lies in clinical vigilance and tailoring management according to emerging needs during pregnancy and follow up. We present a case of twin pregnancy with complete hydatidiform mole and coexisting normal fetus diagnosed at 25 weeks...
January 2024: Pakistan Journal of Medical Sciences Quarterly
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JOURNAL ARTICLE
Ashwin Sharma, Fernanda Erthal, Daniel Juneau, Atif Alzahrani, Ali Alenazy, Samia Massalha, Yeung Yam, Bilaal Kabir, Gary R Small, Benjamin J W Chow
PURPOSE: Coronary computed tomography angiography (CCTA) is an important non-invasive tool for the assessment of coronary artery disease and the delivery of information incremental to coronary anatomy. CCTA measured left ventricular (LV) mid-diastolic volume (LVMDV ) and LV mass (LVMass ) have important prognostic information but the utility of prospectively ECG-triggered CCTA to predict reduced left ventricular ejection fraction (LVEF) is unknown. The objective of this study was to determine if indexed LVMDV (LVMDVi ) and the LVMDV :LVMass ratio on CCTA can identify patients with reduced LVEF...
2024: Journal of Cardiovascular Computed Tomography
#8
JOURNAL ARTICLE
Soumaya Boussaid, Rania Ben Aissa, Sonia Rekik, Safa Rahmouni, Samia Jammali, Khaoula Zouaoui, Hela Sahli, Mohamed Elleuch
BACKGROUND: The clinical screening of enthesitis and synovitis in patients with psoriasis lacks specificity and sensitivity during the preclinical phase. AIMS: to assess US subclinical synovitis and enthesitis in psoriatic patients compared with healthy controls. METHODS: A cross-sectional study on 40 psoriatic patients and 40 healthy sex- and age-matched controls. US examination of 18 joints was performed along with 22 entheseal sites on the upper and lower limbs...
December 2023: Mediterranean journal of rheumatology
#9
JOURNAL ARTICLE
Adel A Abbas, Mohamed F Allam, Hala S Sweed, Samia A Abdul-Rahman, Walaa W Ali
Background Fragility fractures are linked to significant costs for society as well as significant pain and suffering, disability, and even death. It is well-recognized that osteoporosis-related fragility fractures raise the risk of subsequent fragility fractures. One of the most frequent osteoporotic fractures brought on by low bone mineral density and other risk factors is vertebral fractures. Considering that most vertebral fractures are asymptomatic and not clinically identified, proactive screening could stop additional impairment...
December 2023: Curēus
#10
JOURNAL ARTICLE
Nagla H M Khalid, Jihan I Babiker, Samia A Fathelrahman
The study was a prospective cross-sectional design and was carried out at the Maternity and Children's Hospital in Najran, Saudi Arabia on 142 pregnant women . The objective of the study was to establish, utilising ultrasound scan , whether there is any link between the site of the placenta and the gender of the fetus. A higher percentage of female fetuses were identified. The majority of placentas (73, 51.4%) were found to be anterior, of which 66 (46.5%) and 7 (4.9%) were present in female and male fetuses, respectively...
December 31, 2023: African Journal of Reproductive Health
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JOURNAL ARTICLE
Amany Selim Attia, Samia Hussein, Hend Sameh, Amr Khalil, Ahmad Barakat Waley, Ihab Matar, Reham Sameh
BACKGROUND: Papillary thyroid carcinoma (PTC) is the most frequent thyroid malignancy. Histopathological examination is widely accepted as the gold standard test for the diagnosis of PTC. However, the histopathological examination sometimes can't differentiate PTC from other thyroid diseases. Differentiating PTC from other thyroid diseases is essential for a therapeutic approach and prognosis. OBJECTIVES: The current study was performed to investigate the utility of TROP-2, SPL-2, and CXCL12 mRNA and protein expression in discriminating PTC from other thyroid diseases that mimic PTC...
November 23, 2023: Cancer Biomarkers: Section A of Disease Markers
#12
JOURNAL ARTICLE
Natalie Bloch-Isenberg, Robert Zukermann, Samia Massalha, Majd Qasum, Anat Reiner Benaim, Erez Marcusohn
BACKGROUND: Transesophageal echocardiography (TEE) is the gold standard test for the diagnosis of left atrial appendage (LAA) thrombus. Nonetheless, computerized tomography angiography (CTA) is readily used to exclude LAA thrombus before pulmonary vein isolation (PVI) and LAA closure procedures. We aimed to assess the comparability of LAA thrombus diagnosis using chest CTA scans in patients with atrial fibrillation who underwent TEE. METHODS: Retrospective collection of consecutive patients with atrial fibrillation who underwent TEE and chest CTA within 30 days and had evidence of spontaneous echo contrast (SEC) or LAA thrombus on TEE...
December 5, 2023: Journal of Cardiovascular Medicine
#13
JOURNAL ARTICLE
Urvashee Gogoi, Neelutpal Gogoi, Sanchaita Rajkhowa, Shah Alam Khan, Nisreen Daffa Alla Omer Hajedris, Nawal Al-Hoshani, Samia T Al-Shouli, Aparoop Das
The DNA topoisomerase II (topo II) enzyme plays an important role in the replication, recombination, and repair of DNA. Despite their widespread applications in cancer therapy, new, selective, and potent topo II inhibitors with better pharmaceutical profiles are needed to handle drug resistance and severe adverse effects. In this respect, an array of 36 new anticancer compounds was designed based on a Xanthone core tethered to multifunctional Pyridine-amines and Imidazole scaffold via alkyl chain linkers. An integrated in silico approach was used to understand the structural basis and mechanism of inhibition of the hybrid xanthone derivatives...
November 17, 2023: Journal of Biomolecular Structure & Dynamics
#14
JOURNAL ARTICLE
Abeer Abd El-Rahman Mohamed, Samia ElHusseini Abd-ElMageed ElKholy, Rasha Salah Eweida, Reham Magdy Mohammed AbdElsalam
BACKGROUND: Climate change is a rapidly evolving public health problem warranting global attention in the 21st century. The World Health Organization declared that climate illiteracy is highly prevalent among older adults, especially in lower- and middle-income nations. AIM: To determine the effect of the Information-Motivation-Behavioral Skills Model-based intervention for climate change management practices among older adults. DESIGN: A quasi-experimental employed a pre-posttest, two-group research design...
November 14, 2023: Geriatric Nursing
#15
JOURNAL ARTICLE
Fozia Batool, Rahman Qadir, Fatima Adeeb, Samia Kanwal, Ehab A Abdelrahman, Sobia Noreen, Bedur Faleh A Albalawi, Muhammad Mustaqeem, Muhammad Imtiaz, Allah Ditta, Humaira Yasmeen Gondal
Biochar derived from plant biomass has great potential for the decontamination of aqueous media. It is the need of the hour to test biochar derived from economical, easily available, and novel materials. In this regard, the present study provides insight into the sorption of two heavy metals, i.e., cadmium (Cd) and nickel (Ni), using native Arachis hypogaea and its biochar prepared through pyrolysis. The effect of different factors, including interaction time, initial concentration of adsorbate, and temperature, as well as sorbent dosage, was studied on the sorption of Cd and Ni through a batch experiment...
October 31, 2023: ACS Omega
#16
JOURNAL ARTICLE
Muhammad Suleman, Muhammad Saqib, Hassan Mumtaz, Muhammad Iftikhar, Ali Raza, Samia Rauf Butt, Kenza Manahal Talha
Heart failure with preserved ejection fraction is a complex clinical syndrome associated with a high level of morbidity and mortality, constituting 56% of heart failure cases and showing an increasing prevalence. The E/Ea ratio, used for echocardiographic assessment of left ventricular (LV) filling pressure, has been commonly recommended as a noninvasive measure. However, its validity lacks robust prospective validation in patients with preserved LV ejection fraction, and its accuracy has been questioned in comparison to patients with reduced LV ejection fraction...
November 2023: Annals of Medicine and Surgery
#17
JOURNAL ARTICLE
Neil Graham, Karl Zimmerman, Amanda J Heslegrave, Ashvini Keshavan, Federico Moro, Samia Abed-Maillard, Adriano Bernini, Vincent Dunet, Elena Garbero, Giovanni Nattino, Arturo Chieregato, Enrico Fainardi, Camelia Baciu, Primoz Gradisek, Sandra Magnoni, Mauro Oddo, Guido Bertolini, Jonathan M Schott, Henrik Zetterberg, David Sharp
BACKGROUND: Traumatic brain injury (TBI) is associated with the tauopathies Alzheimer's disease and chronic traumatic encephalopathy. Advanced immunoassays show significant elevations in plasma total tau (t-tau) early post-TBI, but concentrations subsequently normalise rapidly. Tau phosphorylated at serine-181 (p-tau181) is a well-validated Alzheimer's disease marker that could potentially seed progressive neurodegeneration. We tested whether post-traumatic p-tau181 concentrations are elevated and relate to progressive brain atrophy...
October 13, 2023: Journal of Neurology, Neurosurgery, and Psychiatry
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JOURNAL ARTICLE
Salma Mosaad Batta, Nashwa Naeem El Far, Nema Ali Soliman, Samia Othman Nassar
BACKGROUND: Activation of the NLRC4 inflammasome appears to start many signalling processes inside the host, including caspase-1, the principal protease responsible for converting proIL-1β and IL-18 to active, secreted IL-1β and IL-18, resulting in pyroptosis. AIMS: To evaluate NLRC4 level in patient's blood serum to highlight its role in the pathogenesis of leprosy. MATERIALS AND METHODS: This prospective study was conducted on 40 patients with leprosy and 30 healthy individuals of matched ages and sexes...
2023: Indian Journal of Dermatology
#19
JOURNAL ARTICLE
Samia A Tawfik, Maha A Hegazy, Nariman A El-Ragehy, Ghada A Sedik
Three novel, simple and accurate multivariate spectrophotometric assisted mathematical techniques were developed for determination of paracetamol, caffeine, drotaverine HCl and their related impurities. The used multivariate algorithms are principal component regression (PCR), partial least squares (PLS), and synergy intervals partial least squares (siPLS). Linearity of the suggested methods was found to be (1.00-14.60, 1.40-7.00, 1.40-3.80, 1.00-3.00, 1.50-3.50 and 2.50-4.50 µg/mL) for paracetamol, caffeine, drotaverine HCl, and their related impurities; p-aminophenol, theophylline and homoveratric acid, correspondingly...
October 5, 2023: BMC chemistry
#20
REVIEW
Samia Ouasti, Johanna Ilic, Camille Mimoun, Sofiane Bendifallah, Cyrille Huchon, Lobna Ouldamer, Jerome Lorenzini, Vincent Lavoué, Emilie Raimond, Ludivine Dion, Hélène Costaz, Pierre-Francois Dupre, Olivier Graesslin, Jennifer Uzan, Yohan Kerbage, Pauline Chauvet, Geoffroy Canlorbe, Cyril Touboul, Yohann Dabi
OBJECTIVES: Obesity is known to be both a major risk factor for endometrial cancer and associated with surgical complexity. Therefore, the management of patients with obesity is a challenge for surgeons and oncologists. The aim of this study is to assess the adherence to European Society of Gynaecological Oncology (ESGO) guidelines in morbidly obese patients (body mass index (BMI) >40 kg/m2 ). The secondary objectives were the impact on overall survival and recurrence-free survival...
October 3, 2023: International Journal of Gynecological Cancer
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