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https://www.readbyqxmd.com/read/29450198/parvovirus-b19-what-is-the-relevance-in-transfusion-medicine
#1
REVIEW
David Juhl, Holger Hennig
Parvovirus B19 (B19V) has been discovered in 1975. The association with a disease was unclear in the first time after the discovery of B19V, but meanwhile, the usually droplet transmitted B19V is known as the infectious agent of the "fifth disease," a rather harmless children's illness. But B19V infects erythrocyte progenitor cells and thus, acute B19V infection in patients with a high erythrocyte turnover may lead to a life-threatening aplastic crisis, and acutely infected pregnant women can transmit B19V to their unborn child, resulting in a hydrops fetalis and fetal death...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29447730/no-163-gynaecological-and-obstetric-management-of-women-with-inherited-bleeding-disorders
#2
Christine Demers, Christine Derzko, Michele David, Joanne Douglas
OBJECTIVE: The prevalence of bleeding disorders, notably von Willebrand disease (vWD), among adult women with objectively documented menorrhagia is consistently reported to be 10% to 20% and is even higher in adolescents presenting with menorrhagia. OPTIONS: Diagnostic tools and specific medical and, where appropriate, surgical alternatives to management are reviewed and evidence-based recommendations presented. EVIDENCE: A MEDLINE search of the English literature between January 1975 and November 2003 was performed using the following key words: menorrhagia, uterine bleeding, pregnancy, von Willebrand, congenital bleeding disorder, desmopressin/DDAVP, tranexamic acid, oral contraceptives, medroxyprogesterone, therapy, hysterectomy, anesthesia, epidural, spinal...
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29446212/free-dialysis-in-nepal-logistical-challenges-explored
#3
John Mcgee, Bimal Pandey, Abhishek Maskey, Tifany Frazer, Theodore Mackinney
Nepal's Ministry of Health began offering free lifetime hemodialysis (HD) in 2016. There has been a large growth in renal replacement therapy (RRT) services offered in Nepal since 2010, when the last known data on the subject was published. In 2016, 42 HD centers existed (223% increase since 2010) serving 1975 end stage renal disease patients (303% increase since 2010); 36 nephrologists were registered (200% increase since 2010), 12 were trained in transplantation, and 790 transplants had been performed to date...
February 15, 2018: Hemodialysis International
https://www.readbyqxmd.com/read/29445729/-brucella-antibodies-in-alaskan-true-seals-and-eared-seals-two-different-stories
#4
Ingebjørg H Nymo, Rolf Rødven, Kimberlee Beckmen, Anett K Larsen, Morten Tryland, Lori Quakenbush, Jacques Godfroid
Brucella pinnipedialis was first isolated from true seals in 1994 and from eared seals in 2008. Although few pathological findings have been associated with infection in true seals, reproductive pathology including abortions, and the isolation of the zoonotic strain type 27 have been documented in eared seals. In this study, a Brucella enzyme-linked immunosorbent assay (ELISA) and the Rose Bengal test (RBT) were initially compared for 206 serum samples and a discrepancy between the tests was found. Following removal of lipids from the serum samples, ELISA results were unaltered while the agreement between the tests was improved, indicating that serum lipids affected the initial RBT outcome...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29443856/complications-in-tube-thoracostomy-systematic-review-and-meta-analysis
#5
Matthew C Hernandez, Moustafah El Khatib, Larry Prokop, Martin D Zielinski, Johnathon M Aho
BACKGROUND: Tube thoracostomy (TT) complications and their reported rates are highly variable (1-40%) and inconsistently classified. Consistent TT complication classification must be applied to compare reported literature to standardize TT placement. We aim to determine the overall TT related complication rates in patients receiving TT for traumatic indications utilizing uniform definitions. METHOD: Systematic review and meta-analysis was performed assessing TT related complications...
February 14, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29438464/intra-generational-social-mobility-and-changes-in-blood-pressure-longitudinal-analysis-from-the-elsa-brasil-study
#6
J M N Guimarães, R H Griep, P J Clarke, M J M Fonseca, S M Barreto, L Giatti, P A Lotufo, J G Mill, A G Pacheco, D Chor
Background: During the past four decades, the highest worldwide blood pressure (BP) levels have shifted from high-income countries to low- and middle-income countries. We investigated the association of intra-generational social mobility with changes in BP and also with the incidence of hypertension over a 4-year follow-up. Methods: Data for 6529 baseline participants from ELSA-Brasil born between 1938 and 1975 were used. Based on a social mobility matrix, occupational social mobility was defined as the change in occupational social class between participants' first occupation and current occupation (stable high; upward; downward; stable low)...
February 9, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29423097/primary-breast-diffuse-large-b-cell-lymphoma-a-population-based-study-from-1975-to-2014
#7
Yijun Jia, Chenbo Sun, Zebing Liu, Weige Wang, Xiaoyan Zhou
Primary breast diffuse large B-cell lymphoma (DLBCL) is a rare non-Hodgkin's lymphoma with limited data. In this study, a population-based study of primary breast DLBCL in the United States was performed to determine its incidence trends, prognostic factors, survival, the role of surgery as well as the comparison with nodal DLBCL. 1021 patients diagnosed with breast DLBCL were identified in the Surveillance, Epidemiology, and End Results (SEER) cancer registries from 1973-2014. The incidence of both breast and nodal DLBCL increased over time...
January 9, 2018: Oncotarget
https://www.readbyqxmd.com/read/29422042/scoping-out-the-literature-on-mobile-needle-and-syringe-programs-review-of-service-delivery-and-client-characteristics-operation-utilization-referrals-and-impact
#8
REVIEW
Carol Strike, Miroslav Miskovic
BACKGROUND: Needle and syringe program (NSP) service delivery models encompass fixed sites, mobile services, vending machines, pharmacies, peer NSPs, street outreach, and inter-organizational agreements to add NSP services to other programs. For programs seeking to implement or improve mobile services, access to a synthesis of the evidence related to mobile services is beneficial, but lacking. METHODS: We used a scoping study method to search MEDLINE, PSYCHInfo, Embase, Scopus, and Sociological for relevant literature...
February 8, 2018: Harm Reduction Journal
https://www.readbyqxmd.com/read/29421373/high-risk-high-reward-daily-perceptions-of-social-challenge-and-performance-in-social-anxiety-disorder
#9
Dan V Blalock, Todd B Kashdan, Patrick E McKnight
Individuals with Social Anxiety Disorder (SAD) have difficulty engaging in social situations because their actions are predicated on minimizing the subjectively biased high potential for rejection. That is, individuals with SAD frequently perceive social situations as challenging, and their performance as subpar. Yet when individuals perceive themselves as succeeding in challenging situations, they typically report these situations as enjoyable and rewarding. This subjective experience of succeeding in a challenging situation has been studied as flow (Csikszentmihalyi, 1975; 2000)...
February 3, 2018: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29420716/racial-ethnic-disparities-in-the-lifetime-risk-of-chlamydia-trachomatis-diagnosis-and-adverse-reproductive-health-outcomes-among-women-in-king-county-washington
#10
Laura C Chambers, Christine M Khosropour, David A Katz, Julia C Dombrowski, Lisa E Manhart, Matthew R Golden
Background: Chlamydia trachomatis is the most common reportable infection in the US and can cause pelvic inflammatory disease (PID) and tubal factor infertility (TFI). Methods: We created lifetables to estimate the "lifetime" risk of chlamydia diagnosis among women age 15-34 in King County, Washington, US, 1992-2014. We estimated the lifetime risk of chlamydia-associated PID and TFI, incorporating published estimates of the risk of sequelae by chlamydia testing history...
February 6, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29415771/bibliometric-analysis-of-global-scientific-activity-on-umbilical-cord-mesenchymal-stem-cells-a-swiftly-expanding-and-shifting-focus
#11
REVIEW
Jian Zhao, Guanyu Yu, Mengxi Cai, Xiao Lei, Yanyong Yang, Qijin Wang, Xiao Zhai
Several studies have focused on umbilical cord-derived mesenchymal stem cells (UC-MSCs) due to their potential therapeutic effects in a cluster of diseases. However, there has been no bibliometric analysis evaluating the evolution in UC-MSC research. Therefore, this study aimed to assess scientific activity regarding UC-MSC research. Publications on UC-MSCs were retrieved from the Science Citation Index-Expanded (SCI-E) of the Web of Science (WoS) from 1975 to 2017. Statistical analyses were performed using Excel, GraphPad Prism 5, and VOSviewer software...
February 7, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29410416/broad-and-long-lasting-immune-protection-against-various-chikungunya-genotypes-demonstrated-by-participants-in-a-cross-sectional-study-in-a-cambodian-rural-community
#12
Heidi Auerswald, Camille Boussioux, Saraden In, Sokthearom Mao, Sivuth Ong, Rekol Huy, Rithea Leang, Malen Chan, Veasna Duong, Sowath Ly, Arnaud Tarantola, Philippe Dussart
Chikungunya virus (CHIKV) is an alphavirus circulating worldwide. Its presence in Asia has been reported since the 1950s, constituting the Asian genotype. Since 2005, strains from the Eastern, Central, and Southern African (ECSA) genotype have caused several outbreaks across Asia. Viruses from the ECSA genotype were also detected in Cambodia in late 2011 and led to an outbreak in a rural community in 2012. A former investigation from 2012 found a higher risk of infection in people younger than 40 years, suggesting a pre-existing herd immunity in the older Cambodian population due to infection with an Asian genotype...
February 7, 2018: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/29408495/multimodality-management-of-vein-of-galen-malformations-an-institutional-experience
#13
Arthur Hosmann, Ahmed El-Garci, Brigitte Gatterbauer, Gerhard Bavinzski, Engelbert Knosp, Andreas Gruber
BACKGROUND: The Vein of Galen Aneurysmal Malformation (VGM) is a rare intracranial arterio-venous fistula with a dramatic manifestation during infancy and a 100% mortality without treatment. Therapeutic strategies for VGMs have changed over time due to advances in endovascular techniques. We present our experience and multimodality approach within the last 4 decades. METHODS: Retrospective analysis and angiographic review of VGM patients between 1975 and 2016 at our institution...
February 2, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29405816/the-legacy-of-douglas-guthrie-1885-1975-surgeon-and-medical-historian
#14
Iain Macintyre
After graduating in medicine Douglas Guthrie embarked on a career as an ENT surgeon. When his Edinburgh hospital appointment ended in 1936 he began to write History of Medicine, which, thanks to a favourable review by George Bernard Shaw, became a worldwide best seller when first published in 1945. This marked the start of Guthrie's second career as a lecturer in history of medicine at the University of Edinburgh where his prime responsibility was delivering systematic lectures on medical history to medical undergraduates...
January 1, 2018: Journal of Medical Biography
https://www.readbyqxmd.com/read/29404298/clinicopathological-and-molecular-epidemiological-study-of-lung-cancer-patients-seen-at-a-tertiary-care-hospital-in-northern-india
#15
Randeep Singh, Nitesh Rohtagi
Aims: The primary objective of this study was to estimate the clinicopathological and molecular profile of lung cancer patients along with the evaluation of their clinical characteristics at a tertiary care hospital in Northern India. Subjects and Methods: A total of 421 patients with lung cancer histology who were treated at Max Super Speciality Hospitals were included in the study. The study protocol conforms to the ethical guidelines of the 1975 Declaration of Helsinki and permission was obtained from the Ethics Committee before the start of the study...
October 2017: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29402806/gastric-neuroendocrine-tumors-g-nets-incidence-prognosis-and-recent-trend-toward-improved-survival
#16
Zhen Yang, WeiHua Wang, JingFeng Lu, Gaofeng Pan, Zhiyu Pan, Qian Chen, Weiyan Liu, Yanping Zhao
BACKGROUND/AIMS: Gastric neuroendocrine tumors (G-NETs) are uncommon neoplasms that can present with or without clinical symptoms. In this study, we evaluated the incidence, prognosis, and temporal trends of G-NETs. METHODS: We analyzed all cases of G-NETs registered in the Surveillance, Epidemiology, and End Results (SEER) database from 1973 to 2014. Incidence was estimated by age and joinpoint analyses. Survival rates were calculated and survival trends over time were evaluated...
2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29400003/incidence-and-outcome-of-subarachnoid-haemorrhage-in-the-general-and-emergency-department-populations-in-queensland-from-2010-to-2014
#17
Kevin H Chu, Ibrahim Mahmoud, Xiang-Yu Hou, Craig D Winter, Rosalind L Jeffree, Nathan J Brown, Anthony Ft Brown
OBJECTIVES: To determine: (i) incidence and outcome of subarachnoid haemorrhage (SAH) in the general population; and (ii) proportions of SAH in both the general ED population and in ED patients presenting with headache. METHODS: A population-based study in Queensland from January 2010 to December 2014 was conducted. Data were sourced from the Australian Bureau of Statistics, Queensland Hospital Admitted Patient Data Collection linked to the Queensland death registry and ED Information System...
February 5, 2018: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29397200/health-systems-development-in-thailand-a-solid-platform-for-successful-implementation-of-universal-health-coverage
#18
REVIEW
Viroj Tangcharoensathien, Woranan Witthayapipopsakul, Warisa Panichkriangkrai, Walaiporn Patcharanarumol, Anne Mills
Thailand's health development since the 1970s has been focused on investment in the health delivery infrastructure at the district level and below and on training the health workforce. Deliberate policies increased domestic training capacities for all cadres of health personnel and distributed them to rural and underserved areas. Since 1975, targeted insurance schemes for different population groups have improved financial access to health care until universal health coverage was implemented in 2002. Despite its low gross national income per capita in Thailand, a bold decision was made to use general taxation to finance the Universal Health Coverage Scheme without relying on contributions from members...
January 31, 2018: Lancet
https://www.readbyqxmd.com/read/29391472/on-the-defect-structure-of-biaxial-nematic-droplets
#19
C Chiccoli, L R Evangelista, P Pasini, G Skačej, R Teixeira de Souza, C Zannoni
We present a detailed Monte Carlo study of the effects of molecular biaxiality on the defect created at the centre of a nematic droplet with radial anchoring at the surface. We have studied a lattice model based on a dispersive potential for biaxial mesogens [Luckhurst et al., Mol. Phys. 30, 1345 (1975)] to investigate how increasing the biaxiality influences the molecular organisation inside the confined system. The results are compared with those obtained from a continuum theory approach. We find from both approaches that the defect core size increases by increasing the molecular biaxiality, hinting at a non universal behaviour previously not reported...
February 1, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29390904/meta-analysis-of-exercise-training-on-vascular-endothelial-function-in-cancer-survivors
#20
Rhys I Beaudry, Yuanyuan Liang, Steven T Boyton, Wesley J Tucker, R Matthew Brothers, Kathryn M Daniel, Roshni Rao, Mark J Haykowsky
Cancer and cardiovascular disease (CVD) are leading causes of morbidity and mortality in the United States. Vascular endothelial dysfunction, an important contributor in the development of CVD, improves with exercise training in patients with CVD. However, the role of regular exercise to improve vascular function in cancer survivors remains equivocal. We performed a meta-analysis to determine the effect of exercise training on vascular endothelial function in cancer survivors. We searched PubMed (1975 to 2016), EMBASE CINAHL (1937 to 2016), OVID MEDLINE (1948 to 2016), and Cochrane Central Registry of Controlled Trials (1991 to 2016) using search terms: vascular function, endothelial function, flow-mediated dilation [FMD], reactive hyperemia, exercise, and cancer...
January 1, 2018: Integrative Cancer Therapies
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