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https://www.readbyqxmd.com/read/29769042/mpcad-a-multi-scale-radiomics-driven-framework-for-automated-prostate-cancer-localization-and-detection
#1
Farzad Khalvati, Junjie Zhang, Audrey G Chung, Mohammad Javad Shafiee, Alexander Wong, Masoom A Haider
BACKGROUND: Quantitative radiomic features provide a plethora of minable data extracted from multi-parametric magnetic resonance imaging (MP-MRI) which can be used for accurate detection and localization of prostate cancer. While most cancer detection algorithms utilize either voxel-based or region-based feature models, the complexity of prostate tumour phenotype in MP-MRI requires a more sophisticated framework to better leverage available data and exploit a priori knowledge in the field...
May 16, 2018: BMC Medical Imaging
https://www.readbyqxmd.com/read/29732440/computer-aided-diagnosis-of-prostate-cancer-with-mri
#2
Baowei Fei
Multi-parametric magnetic resonance imaging (mp-MRI) has an increasingly important role in the diagnosis of prostate cancer. Due to the large amount of data and variations in mp-MRI, tumor detection can be affected by multiple factors, such as the observer's clinical experience, image quality, and appearance of the lesions. In order to improve the quantitative assessment of the disease and reduce the reporting time, various computer-aided diagnosis (CAD) systems have been designed to help radiologists identify lesions...
September 2017: Current Opinion in Biomedical Engineering
https://www.readbyqxmd.com/read/29731160/contouring-of-prostate-tumors-on-multiparametric-mri-evaluation-of-clinical-delineations-in-a-multicenter-radiotherapy-trial
#3
Marcel A van Schie, Cuong V Dinh, Petra J van Houdt, Floris J Pos, Stijn W T J P Heijmink, Linda G W Kerkmeijer, Alexis N T J Kotte, Raymond Oyen, Karin Haustermans, Uulke A van der Heide
PURPOSE: To date no guidelines are available for contouring prostate cancer inside the gland, as visible on multiparametric (mp-) MRI. We assessed inter-institutional differences in interpretation of mp-MRI in the multicenter phase III FLAME trial. METHODS: We analyzed clinical delineations on mp-MRI and clinical characteristics from 260 patients across three institutes. We performed a logistic regression analysis to examine each institute's weighting of T2w, ADC and Ktrans intensity maps in the delineation of the cancer...
May 3, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29727276/automated-detection-of-clinically-significant-prostate-cancer-in-mp-mri-images-based-on-an-end-to-end-deep-neural-network
#4
Zhiwei Wang, Chaoyue Liu, Danpeng Cheng, Liang Wang, Xin Yang, Kwang-Ting Cheng
Automated methods for detecting clinically significant (CS) prostate cancer (PCa) in multi-parameter magnetic resonance images (mp-MRI) are of high demand. Existing methods typically employ several separate steps, each of which is optimized individually without considering the error tolerance of other steps. As a result, they could either involve unnecessary computational cost or suffer from errors accumulated over steps. In this paper, we present an automated CS PCa detection system, where all steps are optimized jointly in an end-to-end trainable deep neural network...
May 2018: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/29664243/new-technologies-and-techniques-for-prostate-cancer-focal-therapy-a-review-of-the-current-literature
#5
Estefanía Linares-Espinós, Arie Carneiro, Juan I Martínez-Salamanca, Fernando Bianco, Adalberto Castro-Alfaro, Xavier Cathelineau, Massimo Valerio, Rafael Sanchez-Salas
BACKGROUND: The aim of this study was to review the oncological and functional outcomes of new and established primary focal treatments (FT) for localized prostate cancer (PCa). METHODS: We performed a systematic search of published studies on FT for localized PCa using electronic databases (Medline and Embase). These studies included reports on hemiablation, focal ablation and target-ablation. We excluded salvage focal therapy studies and limited the search to those with a minimum of 12 months of follow-up...
April 16, 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29659067/computer-aided-diagnosis-of-prostate-cancer-using-a-deep-convolutional-neural-network-from-multiparametric-mri
#6
Yang Song, Yu-Dong Zhang, Xu Yan, Hui Liu, Minxiong Zhou, Bingwen Hu, Guang Yang
BACKGROUND: Deep learning is the most promising methodology for automatic computer-aided diagnosis of prostate cancer (PCa) with multiparametric MRI (mp-MRI). PURPOSE: To develop an automatic approach based on deep convolutional neural network (DCNN) to classify PCa and noncancerous tissues (NC) with mp-MRI. STUDY TYPE: Retrospective. SUBJECTS: In all, 195 patients with localized PCa were collected from a PROSTATEx database...
April 16, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29611674/augmented-reality-during-robot-assisted-radical-prostatectomy-expert-robotic-surgeons-on-the-spot-insights-after-live-surgery
#7
Francesco Porpiglia, Riccardo Bertolo, Daniele Amparore, Enrico Checcucci, Walter Artibani, Prokar Dasgupta, Francesco Montorsi, Ashutosh Tewari, Cristian Fiori
3D reconstruction of the standard two-dimension cross-sectional imaging has known increasing diffusion. It may represent one of the key points for a tailored treatment planning. Along these lines, we used a novel software for augmented-reality robot-assisted radical prostatectomy (AR-RARP) at our Institution. 3D virtual models of the prostate and the prostate cancer were reconstructed from high resolution (1-mm slices) multi-parametric Magnetic Resonance Imaging (mp-MRI) by M3dics (Turin, Italy). The innovation in the study is represented by the software-based integration of the virtual model inside the Da Vinci (Intuitive, Sunnyvale, CA, USA) robotic console during robotic prostatectomy...
April 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29570456/computer-aided-diagnosis-of-prostate-cancer-on-multi-parametric-mri-comparison-between-pun-and-tofts-models
#8
Simone Mazzetti, Valentina Giannini, Filippo Russo, Daniele Regge
Computer-aided diagnosis (CAD) systems are being increasingly used in clinical setting to report multi-parametric magnetic resonance imaging (mp-MRI) of the prostate. Usually, CAD systems automatically highlight cancer suspicious regions to the radiologist, reducing reader variability and interpretation errors. Nevertheless, implementing this software requires selection of which mp-MRI parameters could better discriminate between malignant and non-malignant regions. To exploit functional information, some parameters are derived from dynamic contrast-enhanced (DCE) acquisitions...
March 23, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29570254/diagnostic-accuracy-of-multiparametric-magnetic-resonance-imaging-in-detecting-extracapsular-extension-in-intermediate-and-high-risk-prostate-cancer
#9
Cristina Dominguez, Mauricio Plata, Juan Guillermo Cataño, Mauricio Palau, Diego Aguirre, Jorge Narvaez, Stephanie Trujillo, Felipe Gómez, Carlos Gustavo Trujillo, Juan Ignacio Caicedo, Camilo Medina
OBJECTIVES: To evaluate the diagnostic performance of preoperative multiparametric magnetic resonance imaging (mp-MRI) as a predictor of extracapsular extension (ECE) and unfavorable Gleason score (GS) in patients with intermediate and high-risk prostate cancer (PCa). MATERIALS AND METHODS: Patients with clinically localized PCa who underwent radical prostatectomy (RP) and had preoperative mp-MRI between May-2011 and December-2013. Mp-MRI was evaluated according to the European Society of Urogenital Radiology MRI prostate guidelines by two different readers...
March 23, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29548365/multiparametric-mp-mri-of-prostate-cancer
#10
REVIEW
Virendra Kumar, Girdhar S Bora, Rajeev Kumar, Naranamangalam R Jagannathan
Prostate cancer (PCa) is one of the most prevalent cancers in men. A large number of men are detected with PCa; however, the clinical behavior ranges from low-grade indolent tumors that never develop into a clinically significant disease to aggressive, invasive tumors that may rapidly progress to metastatic disease. The challenges in clinical management of PCa are at levels of screening, diagnosis, treatment, and follow-up after treatment. Magnetic resonance imaging (MRI) methods have shown a potential role in detection, localization, staging, assessment of aggressiveness, targeting biopsies, etc...
April 2018: Progress in Nuclear Magnetic Resonance Spectroscopy
https://www.readbyqxmd.com/read/29472629/indication-to-pelvic-lymph-nodes-dissection-for-prostate-cancer-the-role-of-multiparametric-magnetic-resonance-imaging-when-the-risk-of-lymph-nodes-invasion-according-to-briganti-updated-nomogram-is-5
#11
Francesco Porpiglia, Matteo Manfredi, Fabrizio Mele, Riccardo Bertolo, Enrico Bollito, Dario Gned, Agostino De Pascale, Filippo Russo, Roberto Passera, Cristian Fiori, Stefano De Luca
BACKGROUND: The Briganti updated nomogram (BN) is the most popular predictive model aiming to predict the presence of lymph node invasion (LNI) in patients with prostate cancer (PCa), but it lacks information obtained by preoperative imaging. The primary aim of the study was to evaluate the role of multiparametric prostate magnetic resonance imaging (mp-MRI) in the indication to perform pelvic lymph nodes dissection (PLND) or not in patients with risk of LNI according to BN below 5%. METHODS: Since March 2012 and September 2016, 310 patients who underwent a preoperative mp-MRI for staging purpose and subsequent robot-assisted extended PLND (RAEPLND) were retrospectively evaluated...
April 2018: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/29437268/using-support-vector-machine-analysis-to-assess-partinmr-a-new-prediction-model-for-organ-confined-prostate-cancer
#12
Jing Wang, Chen-Jiang Wu, Mei-Ling Bao, Jing Zhang, Hai-Bin Shi, Yu-Dong Zhang
BACKGROUND: Partin tables represent the most widely used predictive tool for prostate cancer stage at prostatectomy but with potential limitations. PURPOSE: To develop a new PartinMR model for organ-confined prostate cancer (OCPCA) by incorporating Partin table and mp-MRI with a support vector machine (SVM) analysis. STUDY TYPE: Retrospective. POPULATION: In all, 541 patients with biopsy-confirmed prostate cancer underwent mp-MRI...
February 13, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29420978/multiparametric-mr-imaging-of-the-prostate-interpretation-including-prostate-imaging-reporting-and-data-system-version-2
#13
REVIEW
Alessandro Furlan, Amir A Borhani, Antonio C Westphalen
mp-MRI of the prostate is a complex study that combines anatomic and functional imaging. The complexity of this technique, along with an increasing demand, has brought new challenges to imaging interpretation. The Prostate Imaging Reporting and Data System provides radiologists with guidelines to standardize interpretation. This article discusses the interpretation of the pulse sequences recommended in the Prostate Imaging Reporting and Data System version 2 guidelines, reviews advanced quantitative imaging tools, and discusses future directions...
March 2018: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/29407999/pilot-study-for-supervised-target-detection-applied-to-spatially-registered-multiparametric-mri-in-order-to-non-invasively-score-prostate-cancer
#14
Rulon Mayer, Charles B Simone, William Skinner, Baris Turkbey, Peter Choykey
BACKGROUND: Gleason Score (GS) is a validated predictor of prostate cancer (PCa) disease progression and outcomes. GS from invasive needle biopsies suffers from significant inter-observer variability and possible sampling error, leading to underestimating disease severity ("underscoring") and can result in possible complications. A robust non-invasive image-based approach is, therefore, needed. PURPOSE: Use spatially registered multi-parametric MRI (MP-MRI), signatures, and supervised target detection algorithms (STDA) to non-invasively GS PCa at the voxel level...
March 1, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29371727/role-of-multi-parametric-mp-mri-in-prostate-cancer
#15
Syed Muhammad Nazim, Muhammad Hammad Ather, Basit Salam
Multi-parametric magnetic resonance imaging is increasingly being recommended as standard imaging modality for prostate cancer diagnosis and staging. It comprises structural T2 and T1 sequences supplemented by functional imaging techniques, i.e. diffusion-weighted, dynamic contrast enhanced and spectroscopic imaging. Pre-biopsy multi-parametric magnetic resonance imaging is recommended for both detection and staging as it avoids biopsy artefact, and when normal, has a negative predictive value of 95% for significant cancer...
January 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/29331622/value-of-serial-multiparametric-magnetic-resonance-imaging-and-magnetic-resonance-imaging-guided-biopsies-in-men-with-low-risk-prostate-cancer-on-active-surveillance-after-1-yr-follow-up
#16
Esther Hendrika Johanna Hamoen, Caroline M A Hoeks, Diederik M Somford, Inge M van Oort, Henk Vergunst, Jorg R Oddens, Geert A Smits, Leonard P Bokhorst, J Alfred Witjes, Maroeska M Rovers, Christina A Hulsbergen-van de Kaa, Jelle O Barentsz
BACKGROUND: Active surveillance (AS) aims to reduce overtreatment of low-risk prostate cancer (PC). Incorporating multiparametric magnetic resonance imaging (mp-MRI) and MR-guided biopsy (MRGB) in an AS protocol might contribute to more accurate identification of AS candidates. OBJECTIVE: To evaluate the value of 3T mp-MRI and MRGB in PC patients on AS at inclusion and after 12-mo follow-up. DESIGN, SETTING, AND PARTICIPANTS: Patients with cT1c-cT2 PC, prostate-specific antigen (PSA) ≤10ng/ml, PSA density <0...
January 10, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29325321/-preliminary-applicability-evaluation-of-prostate-imaging-reporting-and-data-system-version-2-diagnostic-score-in-3-0t-multi-parameters-magnetic-resonance-imaging-combined-with-prostate-specific-antigen-density-for-prostate-cancer
#17
M Z Zuo, W L Zhao, C G Wei, C Y Zhang, R Wen, Y F Gu, M J Li, Y Y Zhang, J F Wu, X Li, J K Shen
Objective: To investigate the preliminary applicability of Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) score in the condition of 3.0T multi-parametric magnetic resonance imaging (Mp-MRI) combined with clinical classic indicators for the diagnosis of prostate cancer (PCa). Methods: The clinical and MRI materials of 247 patients of suspicious prostate disease treated in Second Affiliated Hospital of Soochow University from June 2015 to November 2016 were analyzed retrospectively, including 110 cases with PCa and 137 cases without cancer...
December 19, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29279147/seminal-vesicle-invasion-on-multi-parametric-magnetic-resonance-imaging-correlation-with-histopathology
#18
Nikolaos Grivas, Karel Hinnen, Jeroen de Jong, Wilma Heemsbergen, Luc Moonen, Thelma Witteveen, Henk van der Poel, Stijn Heijmink
OBJECTIVES: The pre-treatment risk of seminal vesicle (SV) invasion (SVI) from prostate cancer is currently based on nomograms which include clinical stage (cT), Gleason score (GS) and prostate-specific antigen (PSA). The aim of our study was to evaluate the staging accuracy of 3T (3T) multi-parametric (mp) Magnetic Resonance Imaging (MRI) by comparing the imaging report of SVI with the tissue histopathology. The additional value in the existing prediction models and the role of radiologists' experience were also examined...
January 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29239082/utility-of-early-transperineal-template-guided-prostate-biopsy-for-risk-stratification-in-men-undergoing-active-surveillance-for-prostate-cancer
#19
James Voss, Raj Pal, Shaista Ahmed, Magnus Hannah, Adil Jaulim, Thomas Walton
OBJECTIVE: To assess the accuracy and utility of routine multiparametric magnetic resonance imaging (mpMRI) and transperineal template-guided prostate biopsy (TPB) after enrolment in active surveillance (AS). PATIENTS AND METHODS: From April 2012 to December 2016 consecutive men from our single institution, diagnosed with low- or intermediate-risk prostate cancer on transrectal ultrasonography-guided biopsy, were offered further staging with early mpMRI and TPB within 12 months of diagnosis...
December 14, 2017: BJU International
https://www.readbyqxmd.com/read/29211932/targeted-vs-systematic-robot-assisted-transperineal-magnetic-resonance-imaging-transrectal-ultrasonography-fusion-prostate-biopsy
#20
Johannes Mischinger, Sascha Kaufmann, Giorgio I Russo, Niklas Harland, Steffen Rausch, Bastian Amend, Marcus Scharpf, Lorenz Loewe, Tilman Todenhoefer, Mike Notohamiprodjo, Konstantin Nikolaou, Arnulf Stenzl, Jens Bedke, Stephan Kruck
OBJECTIVE: To evaluate the performance of transperineal robot-assisted (RA) targeted (TB) and systematic (SB) prostate biopsy in primary and repeat biopsy settings. PATIENTS AND METHODS: Patients underwent RA biopsy between 2014 and 2016. Before RA-TB, multiparametric magnetic resonance imaging (mpMRI) was performed. Prostate lesions were scored (Prostate Imaging, Reporting and Data System, version 2) and used for RA-TB planning. In addition, RA-SB was performed...
December 6, 2017: BJU International
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