keyword
MENU ▼
Read by QxMD icon Read
search

Antibiofilm activity

keyword
https://www.readbyqxmd.com/read/28815637/synergistic-antibacterial-and-antibiofilm-efficacy-of-nisin-in-combination-with-p-coumaric-acid-against-foodborne-bacteria-bacillus-cereus-and-salmonella-typhimurium
#1
Anwesa Bag, Rabi Ranjan Chattopadhyay
The aim of the study was to evaluate possible antibacterial and antibiofilm efficacy of a bacteriocin, nisin with two essential oil components linalool and p-coumaric acid in combination against foodborne bacteria Bacillus cereus and Salmonella typhimurium. Their inhibition effects on planktonic cells and pre-formed biofilms were evaluated using microbroth dilution and checkerboard titration methods. Nisin/ p-coumaric acid combination showed synergistic effects against planktonic cells of both the studied bacteria whereas nisin/ linalool combination showed synergistic activity against B...
August 16, 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/28812948/age-related-resistance-in-arabidopsis-thaliana-involves-the-mads-domain-transcription-factor-short-vegetative-phase-and-direct-action-of-salicylic-acid-on-pseudomonas-syringae
#2
Daniel C Wilson, Christine J Kempthorne, Philip Carella, David K Liscombe, Robin Cameron
Arabidopsis thaliana exhibits a developmentally regulated disease-resistance response known as Age-Related Resistance (ARR), a process that requires intercellular accumulation of salicylic acid (SA), which is thought to act as an antimicrobial agent. ARR is characterized by enhanced resistance to some pathogens at the late adult-vegetative and reproductive stages. While the transition to flowering does not cause the onset of ARR, both processes involve the MADS-domain transcription factor SHORT VEGETATIVE PHASE (SVP)...
August 16, 2017: Molecular Plant-microbe Interactions: MPMI
https://www.readbyqxmd.com/read/28802271/antibiofilm-effect-of-poly-vinyl-alcohol-co-ethylene-pva-co-pe-halamine-film-against-listeria-innocua-and-escherichia-coli-o157-h7
#3
Andrea Cossu, Yang Si, Gang Sun, Nitin Nitin
Bacterial biofilm formation is linked to several infections and foodborne disease outbreaks. To address this challenge, there is an unmet need to develop rechargeable antimicrobial materials that can provide continuous sanitation of contact surfaces especially in the food industry. This study was aimed at evaluating a novel rechargeable antimicrobial polymer formed using PVA-co-PE with halamine functionality to prevent biofilm formation with repeated exposure to high loads of bacteria and organic content and also aid in inactivation of pre-formed biofilms upon contact with this novel material...
August 11, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28795889/use-of-an-engineered-honey-to-eradicate-preformed-biofilms-of-important-wound-pathogens-an-in-vitro-study
#4
F D Halstead, M A Webber, B A Oppenheim
OBJECTIVE: We previously reported on the ability of SurgihoneyRO (SHRO), an engineered honey, to prevent biofilm formation in vitro, but data were lacking regarding the activity against preformed biofilms. This study aims to assess whether SHRO has any antibacterial activity against mature, preformed biofilms and whether there is any evidence to support the observed clinical effectiveness when SHRO has been used anecdotally on acute and chronic wounds where biofilm is most likely present...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28795783/low-density-polyethylene-functionalized-with-antibiofilm-compounds-inhibits-escherichia-coli-cell-adhesion
#5
Silvia Dell'Orto, Cristina Cattò, Federica Villa, Fabio Forlani, Espedito Vassallo, Marco Morra, Francesca Cappitelli, Stefania Villa, Arianna Gelain
The present work concerns an efficient strategy to obtain novel medical devices materials able to inhibit biofilm formation. The new materials were achieved by covalent grafting of p-aminocinnamic or p-aminosalicylic acids on low density polyethylene coupons. The polyethylene surface, previously activated by oxygen plasma treatment, was functionalized using 2-hydroxymethylmetacrylate as linker. The latter was reacted with succinic anhydride affording the carboxylic end useful for the immobilization of the antibiofilm molecules...
August 10, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28782933/new-insights-into-antibiofilm-effect-of-a-nanosized-zno-coating-against-the-pathogenic-methicillin-resistant-staphylococcus-aureus
#6
Marta M Alves, Ons Bouchami, Ana Tavares, Laura Córdoba, Catarina F Santos, Maria Miragaia, Maria de Fátima Montemor
ZnO nanoparticles (NPs) are arising as promising novel antibiotics toward device-related infections. The surface functionalization of Zn, a novel resorbable biomaterial, with ZnO NPs could present an effective solution to overcome such a threat. In this sense, the antibacterial and antibiofilm activity of nano- and microsized ZnO coatings was studied against clinically relevant bacteria, methicillin resistant Staphylococcus aureus (MRSA). The bacterial viability of planktonic and biofilm cells together with the corresponding biofilm structures revealed that only the nanosized ZnO coating had an antibiofilm effect...
August 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28767074/comparative-study-on-antistaphylococcal-activity-of-lipopeptides-in-various-culture-media
#7
Maciej Jaśkiewicz, Damian Neubauer, Wojciech Kamysz
Staphylococcus aureus bacteria are one of the leading microorganisms responsible for nosocomial infections as well as being the primary causative pathogen of skin and wound infections. Currently, the therapy of staphylococcal diseases faces many difficulties, due to a variety of mechanisms of resistance and virulence factors. Moreover, a number of infections caused by S. aureus are connected with biofilm formation that impairs effectiveness of the therapy. Short cationic lipopeptides that are designed on the basis of the structure of antimicrobial peptides are likely to provide a promising alternative to conventional antibiotics...
August 2, 2017: Antibiotics
https://www.readbyqxmd.com/read/28761101/a-short-d-enantiomeric-antimicrobial-peptide-with-potent-immunomodulatory-and-antibiofilm-activity-against-multidrug-resistant-pseudomonas-aeruginosa-and-acinetobacter-baumannii
#8
Mohamed F Mohamed, Anna Brezden, Haroon Mohammad, Jean Chmielewski, Mohamed N Seleem
Antimicrobial peptides (AMPs) represent a promising therapeutic alternative for the treatment of antibiotic-resistant bacterial infections. The present study investigates the antimicrobial activity of new, rationally-designed derivatives of a short α-helical peptide, RR. From the peptides designed, RR4 and its D-enantiomer, D-RR4, emerged as the most potent analogues with a more than 32-fold improvement in antimicrobial activity observed against multidrug-resistant strains of Pseudomonas aeruginosa and Acinetobacter baumannii...
July 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28755874/antibiofilm-potential-of-synthetic-2-amino-5-chlorobenzophenone-schiff-bases-and-its-confirmation-through-fluorescence-microscopy
#9
Arshia, Anum Khalid Khan, Khalid Mohammed Khan, Ayaz Ahmed, Muhammad Taha, Shahnaz Perveen
Antibacterial/antibiofilm potential of microwave-assisted synthetic thirty-three 2-amino-5-chloro benzophenone Schiff bases have been carried out against four bacterial strains i.e. Klebsiella pneumoniae, Proteus mirabilis, Staphylococcus aureus and Streptococcus mutans. Among them compounds 5, 6, 8, 9, 14, 16, 22, 24, 26, and 30-32 showed antibiofilm activities against isolates at less than 100 μg/ml concentrations. These compounds showed enhanced antibiofilm activity against S. aureus as compared to cefixime used as control...
July 26, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28745297/foley-catheters-functionalised-with-a-synergistic-combination-of-antibiotics-and-silver-nanoparticles-resist-biofilm-formation
#10
Rajendran Mala, Antony Annie Aglin, Arul Selvaraj Ruby Celsia, Sivalingam Geerthika, Narbahvi Kiruthika, Chinnathambi VazagaPriya, Kumarapillai Srinivasa Kumar
Foley catheters are inevitable in health care unit. Pathogens colonise and form biofilm on catheter causing catheter-associated urinary tract infection. Therefore, the authors aimed to functionalise catheter to resist biofilm formation. The authors impregnated urinary catheters with a synergistic combination of antibiotics and silver nanoparticles (SNPs) to evaluate antibiofilm efficacy in vitro and in vivo. SNPs were synthesised using Spirulina platensis. Synergy between the SNPs and antibiotics was determined by the checker-board method...
August 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/28744275/staphylococcus-aureus-quorum-regulator-sara-targeted-compound-2-methylamino-methyl-phenol-inhibits-biofilm-and-down-regulates-virulence-genes
#11
P Balamurugan, V Praveen Krishna, D Bharath, Raajaraam Lavanya, Pothiappan Vairaprakash, S Adline Princy
Staphylococcus aureus is a widely acknowledged Gram-positive pathogen for forming biofilm and virulence gene expressions by quorum sensing (QS), a cell to cell communication process. The quorum regulator SarA of S. aureus up-regulates the expression of many virulence factors including biofilm formation to mediate pathogenesis and evasion of the host immune system in the late phases of growth. Thus, inhibiting the production or blocking SarA protein might influence the down-regulation of biofilm and virulence factors...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28731688/the-%C3%AF-configuration-of-the-www-motif-of-a-short-trp-rich-peptide-is-critical-for-targeting-bacterial-membranes-disrupting-preformed-biofilms-and-killing-methicillin-resistant-staphylococcus-aureus
#12
D Zarena, Biswajit Mishra, Tamara Lushnikova, Fangyu Wang, Guangshun Wang
Tryptophan-rich peptides, being short and suitable for large-scale chemical synthesis, are attractive candidates for developing a new generation of antimicrobials to combat antibiotic-resistant bacteria (superbugs). Although there are numerous pictures of the membrane-bound structure of a single tryptophan (W), how multiple Trp amino acids assemble themselves and interact with bacterial membranes is poorly understood. This communication presents the three-dimensional structure of an eight-residue Trp-rich peptide (WWWLRKIW-NH2 with 50% W) determined by the improved two-dimensional nuclear magnetic resonance method, which includes the measurements of (13)C and (15)N chemical shifts at natural abundance...
July 26, 2017: Biochemistry
https://www.readbyqxmd.com/read/28723923/on-the-mechanism-of-candida-tropicalis-biofilm-reduction-by-the-combined-action-of-naturally-occurring-anthraquinones-and-blue-light
#13
Juliana Marioni, Roger Bresolí-Obach, Montserrat Agut, Laura R Comini, José L Cabrera, María G Paraje, Santi Nonell, Susana C Núñez Montoya
The photoprocesses involved in the photo-induced Candida tropicalis biofilm reduction by two natural anthraquinones (AQs), rubiadin (1) and rubiadin-1-methyl ether (2), were examined. Production of singlet oxygen (1O2) and of superoxide radical anion (O2•-) was studied. Although it was not possible to detect the triplet state absorption of any AQs in biofilms, observation of 1O2 phosphorescence incubated with deuterated Phosphate Buffer Solution, indicated that this species is actually formed in biofilms...
2017: PloS One
https://www.readbyqxmd.com/read/28719354/thymol-and-carvacrol-strongly-inhibit-biofilm-formation-and-growth-of-carbapenemase-producing-gram-negative-bacilli
#14
P Raei, T Pourlak, M Y Memar, N Alizadeh, M Aghamali, E Zeinalzadeh, M Asgharzadeh, H S Kafil
Discovery of novel drugs with new mechanisms of action and without cross-reaction with current therapeutic agents is crucial in the management of infections caused by multi-drug resistant (MDR) bacteria. The aim of the present study was to investigate effects of carvacrol and thymol on biofilm formation and antimicrobial activity against different carbapenemase-producing Gram negative bacilli. The antimicrobial and antibiofilm effect of thymol and carvacrol was investigated against strains harboring different genes related to carbapenemase resistance...
May 20, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28710012/antibiofilm-activity-of-vetiveria-zizanioides-root-extract-against-methicillin-resistant-staphylococcus-aureus
#15
Arunachalam Kannappan, Shanmugaraj Gowrishankar, Ramanathan Srinivasan, Shunmugiah Karutha Pandian, Arumugam Veera Ravi
Methicillin-resistant Staphylococcus aureus (MRSA) is a leading human pathogen responsible for causing chronic clinical manifestation worldwide. In addition to antibiotic resistance genes viz. mecA and vanA, biofilm formation plays a prominent role in the pathogenicity of S. aureus by enhancing its resistance to existing antibiotics. Considering the role of folk medicinal plants in the betterment of human health from the waves of multidrug resistant bacterial infections, the present study was intended to explore the effect of Vetiveria zizanioides root on the biofilm formation of MRSA and its clinical counterparts...
July 11, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28709400/broad-range-potential-of-asphodelus-microcarpus-leaves-extract-for-drug-development
#16
Amalia Di Petrillo, Antonella Fais, Francesca Pintus, Celestino Santos-Buelga, Ana M González-Paramás, Vincenzo Piras, Germano Orrù, Antonello Mameli, Enzo Tramontano, Aldo Frau
BACKGROUND: Many plants have been used in traditional medicine for their antibacterial, antifungal, antiprotozoal, antiviral, antidiarrhoeal, analgesic, antimalarial, antioxidant, anti-inflammatory and anticancer activities. In order to find novel antimicrobial and antiviral agents, the aim of the present study was the evaluation of the antibacterial and antibiofilm susceptibility of Asphodelus microcarpus leaves extract. Moreover, the antiviral activity and the phytochemical composition of the active extract were also determined...
July 14, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28702002/production-of-lipopeptide-biosurfactant-by-a-marine-nesterenkonia-sp-and-its-application-in-food-industry
#17
George S Kiran, Sethu Priyadharsini, Arya Sajayan, Gopal B Priyadharsini, Navya Poulose, Joseph Selvin
Biosurfactants are smart biomolecules which have wide spread application in medicines, processed foods, cosmetics as well as in bioremediation. In food industry, biosurfactants are used as emulsion stabilizing agents, antiadhesives, and antimicrobial/antibiofilm agents. Nowadays biosurfactant demands in industries has increased tremendously and therefore new bacterial strains are being explored for large scale production of biosurfactants. In this study, an actinobacterial strain MSA31 was isolated from a marine sponge Fasciospongia cavernosa which showed high activity in biosurfactant screening assays such as drop collapsing, oil displacement, lipase and emulsification...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28694794/antivirulent-properties-of-underexplored-cinnamomum-tamala-essential-oil-and-its-synergistic-effects-with-dnase-against-pseudomonas-aeruginosa-biofilms-an-in-vitro-study
#18
Sanaulla Farisa Banu, Durairajan Rubini, Sairam Rakshitaa, Kamaraj Chandrasekar, Ramar Murugan, Aruni Wilson, Shanmugaraj Gowrishankar, Shunmugiah Karutha Pandian, Paramasivam Nithyanand
Pseudomonas aeruginosa is a nosocomial pathogen colonizing patients with chronic infectious diseases and has gained resistance to all the known broad spectrum antibiotics available today. The present study showcases the antibiofilm potential of an essential oil (EO) from an underexplored Cinnamomum species namely, C. tamala, against P. aeruginosa biofilms. Furthermore, the synergistic effects of the EO along with a commercially available DNase (DNaseI) and a DNase (MBD) isolated from a marine bacterium were explored for its antibiofilm activity...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28692914/antibiofilm-potential-of-16-oxo-cleroda-3-13-14-e-diene-15-oic-acid-and-its-five-new-%C3%AE-amino-%C3%AE-lactone-derivatives-against-methicillin-resistant-staphylococcus-aureus-and-streptococcus-mutans
#19
Anum Khalid Khan, Ayaz Ahmed, Mustafa Hussain, Ishtiaq Ahmad Khan, Syed Abid Ali, Ahsana Dar Farooq, Shaheen Faizi
The clerodane diterpenoids 16-oxo-cleroda-3, 13(14) E-diene-15 oic acid (1) and kolavenic acid (2) isolated from Polyalthia longifolia var. pendula (Linn.) were previously reported for their antimicrobial activity. Thus present study was designed to investigate the biofilm inhibiting potential of these diterpenoids (1-2) and five new lactone derivatives (3-7) of 1 against methicillin resistant Staphylococcus aureus (MRSA), Streptococcus mutans, Klebsiella pneumoniae and Proteus mirabilis. Compounds 1 and 3 at 10-20 μg/mL were found to be bacteriostatic and significantly reduced the biofilm formation and metabolically active cells of MRSA and S...
June 29, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28690982/deferiprone-and-gallium-protoporphyrin-have-the-capacity-to-potentiate-the-activity-of-antibiotics-in-staphylococcus-aureus-small-colony-variants
#20
Katharina Richter, Nicky Thomas, Guimin Zhang, Clive A Prestidge, Tom Coenye, Peter-John Wormald, Sarah Vreugde
Small colony variants (SCVs) of bacteria like Staphylococcus aureus are characterized by a reduced colony size and are linked to increased antibiotic tolerance and resistance. Their altered expression of virulence factors, slow growing properties and their ability to form biofilms make the eradication of SCVs challenging. In the context of biofilm-related infectious diseases involving S. aureus SCVs, a therapy targeting bacterial iron metabolism was evaluated. The combination of the iron-chelator deferiprone (Def) and the heme-analog gallium-protoporphyrin (GaPP), in solution and incorporated in a surgical wound gel, was tested for activity against planktonic and sessile SCVs...
2017: Frontiers in Cellular and Infection Microbiology
keyword
keyword
90776
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"