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https://www.readbyqxmd.com/read/29778051/assessing-psychopathy-in-forensic-schizophrenia-spectrum-disorders-validating-the-comprehensive-assessment-of-the-psychopathic-personality-institutional-rating-scale-capp-irs
#1
Louis De Page, Sophie Mercenier, Pierre Titeca
The assessment of psychopathy in (forensic) schizophrenia spectrum disorders is long-standing debate. In the present study, we investigated the psychometric properties of the Comprehensive Assessment of Psychopathic Personality-Institutional Rating Scale (CAPP-IRS) in a sample of 72 male forensic patients with a primary diagnosis of schizophrenia spectrum disorders. We compared the CAPP-IRS' psychometric properties to those of the Psychopathy Checklist-Revised (PCL-R). The CAPP-IRS showed good interrater reliability and internal consistency except for the CAPP-IRS Cognition and Emotional Domains...
May 16, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29777811/electrospun-chitosan-polycaprolactone-hyaluronic-acid-bilayered-scaffold-for-potential-wound-healing-applications
#2
Amit Chanda, Jaideep Adhikari, Aritri Ghosh, Sougata Roy Chowdhury, Sabu Thomas, Pallab Datta, Prosenjit Saha
Fabrication of mechanically stable, biocompatible bilayered polymeric scaffold consisting of chitosan(CS)/polycaprolactone(PCL) and hyaluronic acid(HA) using less toxic solvent system is presented in this study. Electrospinning technique to make the scaffold was used followed by morphological, physiochemical and mechanical characterizations. Average fiber diameter of CS/PCL-HA bilayered scaffold was found 362.2 ± 236 nm which is in the range of collagen fiber found in the extracellular matrices. Enhanced swelling, degradation, hydrophilicity and water vapour transmission rate were found for the bilayered scaffold compared to that of the PCL and CS-PCL scaffolds...
May 16, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29777233/visceral-adiposity-and-high-adiponectin-levels-are-associated-with-the-prevalence-of-pancreatic-cystic-lesions
#3
Suguru Mizuno, Yousuke Nakai, Hiroyuki Isayama, Takeharu Yoshikawa, Kei Saito, Naminatsu Takahara, Hirofumi Kogure, Minoru Tada, Naoto Hayashi, Kazuhiko Koike
OBJECTIVES: Obesity is increasing in developed countries and is a risk factor for pancreatic cancer (PaC). We previously reported that obesity was associated with pancreatic cystic lesions (PCLs), which are both precursors of, and risk factors for, PaC. In the present study, we further investigated the relationship between visceral adiposity and adiponectin levels and the extent of PCLs. METHODS: Individuals who underwent comprehensive health screening at our institution between January 2008 and March 2013 were analyzed...
May 17, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29776732/posttraumatic-stress-and-depressive-symptoms-characterize-cardiac-arrest-survivors-perceived-recovery-at-hospital-discharge
#4
Alex Presciutti, Jayati Verma, Marykay Pavol, Deepti Anbarasan, Cristina Falo, Daniel Brodie, Leroy E Rabbani, David J Roh, Soojin Park, Jan Claassen, Sachin Agarwal
OBJECTIVE: To test the hypothesis that posttraumatic stress and depressive symptoms, not cognitive or functional impairment, are associated with cardiac arrest survivors' negative recovery perceptions at hospital discharge. METHODS: Prospective observational cohort of cardiac arrest patients admitted between 9/2015-5/2017. Survival to discharge with sufficient mental status to complete a psychosocial interview was the main inclusion criterion. Perceived recovery was assessed through the question, "Do you feel that you have made a complete recovery from your arrest?" The following measures were examined as potential correlates of perceived recovery: Repeatable Battery for Assessment of Neuropsychological Status, Modified Lawton Physical Self-Maintenance Scale, Barthel Index, Modified Rankin Scale, Cerebral Performance Category, Center for Epidemiological Studies-Depression (CES-D), and PTSD Checklist-Specific (PCL-S)...
May 10, 2018: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29775814/composite-self-expanding-bioresorbable-prototype-stents-with-reinforced-compression-performance-for-congenital-heart-disease-application-computational-and-experimental-investigation
#5
Fan Zhao, Wen Xue, Fujun Wang, Laijun Liu, Haoqin Shi, Lu Wang
Stents are vital devices to treat vascular stenosis in pediatric patients with congenital heart disease. Bioresorbable stents (BRSs) have been applied to reduce challenging complications caused by permanent metal stents. However, it remains almost a total lack of BRSs with satisfactory compression performance specifically for children with congenital heart disease, leading to importantly suboptimal effects. In this work, composite bioresorbable prototype stents with superior compression resistance were designed by braiding and annealing technology, incorporating poly (p-dioxanone) (PPDO) monofilaments and polycaprolactone (PCL) multifilament...
May 8, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29775710/dual-ph-sensitive-supramolecular-micelles-from-star-shaped-pdmaema-based-on-%C3%AE-cyclodextrin-for-drug-release
#6
Zaishuai Zhou, Feng Guo, Nairong Wang, Meng Meng, Guiying Li
Star-shaped poly(2-(dimethylamino)ethyl methacrylate) based on β-cyclodextrin (β-CD-(PDMAEMA)7 ) was synthesized by means of atomic transfer radical polymerization (ATRP). Dual pH-sensitive supramolecular micelles were formed from β-CD-(PDMAEMA)7 and benzimidazole modified poly(ε-caprolactone) (BM-PCL) through the host-guest interactions between β-CD and benzimidazole. The supramolecular micelles have regular spherical structure with hydrophobic β-CD/BM-PCL as the core and pH-sensitive PDMAEMA as the shell...
May 15, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29773387/levan-based-fibrous-scaffolds-electrospun-via-co-axial-and-single-needle-techniques-for-tissue-engineering-applications
#7
Gülben Avsar, Deniz Agirbasli, Mehmet Ali Agirbasli, Oguzhan Gunduz, Ebru Toksoy Oner
This represents the first systematic study where levan polysaccharide was used to fabricate fibrous matrices by co-axial and single-needle electrospinning techniques. For this, hydrolyzed (hHL) and sulfated hydrolyzed (ShHL) Halomonas levan were chemically synthesized and used together with polycaprolactone (PCL) and polyethyleneoxide (PEO) for the spinning process. In co-axially spun matrices, ultimate tensile strength (UTS) were found to increase with increasing ShHL concentration and elongation at break of PCL + ShHL matrices increased up to ten-fold when compared to PCL matrices...
August 1, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29773309/posttraumatic-stress-disorder-in-patients-who-rule-out-versus-rule-in-for-acute-coronary-syndrome
#8
Ian M Kronish, Donald Edmondson, Nathalie Moise, Bernard P Chang, Ying Wei, David Lopez Veneros, William Whang
OBJECTIVE: Many patients who present to the emergency department (ED) with acute coronary syndromes (ACS) develop posttraumatic stress disorder (PTSD) due to the experience. Less is known about risk for PTSD in patients who rule out for ACS. Our objective was to compare the risk of developing PTSD among patients who rule out versus rule in for ACS. METHODS: We enrolled a consecutive sample of 1000 patients presenting to an emergency department (ED) with symptoms of a probable ACS...
May 14, 2018: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29772691/periodontal-tissues-maxillary-jaw-bone-and-tooth-regeneration-approaches-from-animal-models-analyses-to-clinical-applications
#9
REVIEW
Fareeha Batool, Marion Strub, Catherine Petit, Isaac Maximiliano Bugueno, Fabien Bornert, François Clauss, Olivier Huck, Sabine Kuchler-Bopp, Nadia Benkirane-Jessel
This review encompasses different pre-clinical bioengineering approaches for periodontal tissues, maxillary jaw bone, and the entire tooth. Moreover, it sheds light on their potential clinical therapeutic applications in the field of regenerative medicine. Herein, the electrospinning method for the synthesis of polycaprolactone (PCL) membranes, that are capable of mimicking the extracellular matrix (ECM), has been described. Furthermore, their functionalization with cyclosporine A (CsA), bone morphogenetic protein-2 (BMP-2), or anti-inflammatory drugs' nanoreservoirs has been demonstrated to induce a localized and targeted action of these molecules after implantation in the maxillary jaw bone...
May 16, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29772384/facile-preparation-of-biocompatible-poly-lactic-acid-reinforced-poly-%C3%AE%C2%B5-caprolactone-fibers-via-graphite-nanoplatelets-aided-melt-spinning
#10
Ivan Kelnar, Alexander Zhigunov, Ludmila Kaprálková, Ivan Fortelný, Jiří Dybal, Jaroslav Kratochvíl, Martina Nevoralová, Marcela Hricová, Viera Khunová
Addition of high-aspect-ratio (AR) nanofillers can markedly influence flow behavior of polymer systems. As a result, application of graphite nanoplatelets (GNP) allows preparation of microfibrillar composites (MFC) based on PCL matrix reinforced with in-situ generated PLA fibrils. This work deals, for the first time, with preparation of analogous melt-drawn fibers. Unlike other blend-based fibers, the spinning and melt drawing leads to structure of deformed inclusions due to unfavorable ratio of rheological parameters of components...
May 9, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29772283/amphiphilic-polyurethane-hydrogels-as-smart-carriers-for-acidic-hydrophobic-drugs
#11
Lucas P Fonseca, Rafael B Trinca, Maria Isabel Felisberti
Amphiphilic hydrogels are widely reported as systems with great potential for controlled drug release. Nevertheless, the majority of studies make use of functionalization or attachment of drugs to the polymer chains. In this study, we propose a strategy of combining amphiphilic polyurethanes with pH-responsive drugs to develop smart drug carriers. While the amphiphilic character of the polymer imparts an efficient load of hydrophobic and hydrophilic drugs, the drug's characteristics determine the selectivity of the medium delivery...
May 14, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29770571/using-poly-l-lactic-acid-and-poly-%C3%A9-caprolactone-blends-to-fabricate-self-expanding-watertight-and-biodegradable-surgical-patches-for-potential-fetoscopic-myelomeningocele-repair
#12
Rigwed Tatu, Marc Oria, Sarah Pulliam, Lorenzo Signey, Marepalli B Rao, Jose L Peiro, Chia-Ying Lin
Our study focuses on the development and characterization of a self-expanding, watertight and biodegradable patch for fetoscopic myelomeningocele (MMC) prenatal repair. We fabricated poly(l-lactic acid) (PLA) and poly(ɛ-caprolactone) (PCL) blend films by solution casting. Formulation c with average glass transition temperature of 37.6 ± 1.2°C was chosen for temporospatial recovery. Favorable results from surface studies reflected homogeneous dispersion of polymers in the blend. The cytotoxicity was studied in human foreskin fibroblasts...
May 16, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29768878/nano-nets-covered-composite-nanofibers-with-enhanced-biocompatibility-and-mechanical-properties-for-bone-tissue-engineering
#13
Arjun Prasad Tiwari, Mahesh Kumar Joshi, Chan Hee Park, Cheol Sang Kim
Enhancing the biocompatibility profiles including cell attachment, growth, and viability and mechanical properties of designed synthetic scaffolds have an essential role in tissue engineering applications. Polymer blending is one of the most effective methods for providing new anticipated biomaterials for tissue scaffolds. Here, the blend solution of the different mass weight ratio of polycaprolactone (PCL) to human serum albumin (HSA) was subjected to fabricate nanocomposite spider-web-like membranes using electrospinning process...
January 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29768632/lower-extremity-limb-salvage-with-cross-leg-pedicle-flap-cross-leg-free-flap-and-cross-leg-vascular-cable-bridge-flap
#14
Oscar J Manrique, Sarah N Bishop, Pedro Ciudad, Kian Adabi, Jorys Martinez-Jorge, Steven L Moran, Tony Huang, Aparna Vijayasekaran, Shih-Heng Chen, Hung-Chi Chen
BACKGROUND:  Lower extremity salvage following significant soft tissue loss can be complicated by lack of recipient vessel for free tissue transfer. We describe our experience in lower limb salvage for patients with no recipient vessels with the use of pedicle, free and cable bridge flaps. METHODS:  A retrospective review from 1985 to 2017 of patients undergoing lower limb salvage using a contralateral pedicle cross leg (PCL) flaps, free cross leg (FCL) flaps, or free cable bridge (FCB) flaps was conducted...
May 16, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29768120/three-dimensionally-printed-pearl-powder-poly-caprolactone-composite-scaffolds-for-bone-regeneration
#15
Xu Zhang, Xiaoyu Du, Dejian Li, Rongguang Ao, Bin Yu, Baoqing Yu
Pearl has great potential as a natural biomaterial for bone tissue engineering, but it suffers from low porosity, difficulty in molding, and poor anti-buckling property. In this study, we used the 3-D printing technique to fabricate original pearl powder and PCL composite scaffolds with different concentrations of pearl powder. The four groups of scaffolds were termed PCL, 30% Pearl/PCL, 50% Pearl/PCL and 80% Pearl/PCL scaffolds according to the proportion of pearl powder. The samples were systematically investigated by scanning electron microscopy (SEM), wide-angle XRD, liquid substitution, Zwick static materials testing, and energy dispersive X-ray analysis...
May 16, 2018: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/29764317/generatehope-a-comprehensive-treatment-model-for-sex-trafficked-women
#16
Susan Munsey, Heather E Miller, Terence Rugg
GenerateHope (GH) is a San Diego-based 501c3 nonprofit organization providing fully integrated, comprehensive rehabilitation services to adult female survivors of sex trafficking. While best practices for working with survivors of sex trafficking are slowly emerging, to date, there have been few publications on this subject and little data on either short- or long-term outcomes from the many and varied programs nationwide. This paper examines the GH residential program and provides early outcome results for residents living at the GH program between six and 12 months...
May 15, 2018: Journal of Evidence-informed Social Work
https://www.readbyqxmd.com/read/29763548/zein-increases-the-cytoaffinity-and-biodegradability-of-scaffolds-3d-printed-with-zein-and-poly-%C3%AE%C2%B5-caprolactone-composite-ink
#17
Linzhi Jing, Xiang Wang, Hang Liu, Yuyun Lu, Jinsong Bian, Jie Sun, Dejian Huang
Electrohydrodynamic printing (EHDP) has attracted extensive interests as a powerful technology to fabricate micro to nanoscale fibrous scaffolds in a custom-tailored manner for biomedical applications. A few synthetic biopolymer inks are applicable to this EHDP technology, but the fabricated scaffolds suffered from low mechanical strength, biocompatibility and biodegradability. In this study, a series of poly(ε-caprolactone)(PCL)/zein composite inks were developed and their printability was examined on a solution-based EHDP system for scaffold fabrication...
May 15, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29761648/poly-%C3%AE-amino-ester-co-poly-caprolactone-terpolymers-as-nonviral-vectors-for-mrna-delivery-in-vitro-and-in-vivo
#18
Umberto Capasso Palmiero, James C Kaczmarek, Owen S Fenton, Daniel G Anderson
The production of new proteins with messenger RNA (mRNA) has gained a broad interest due to its potential for addressing a wide range of diseases. Here, the design and characterization of novel ionizable poly(β-amino ester)-co-poly(caprolactone) terpolymers, synthesized via the combination of the ring opening polymerization and the Michael step-growth polymerization, are reported. The versatility of this method is demonstrated by varying the number of caprolactone units attached to each poly(β-amino ester) (PBAE) terpolymer...
May 14, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29761314/pcl-based-composite-scaffold-matrices-for-tissue-engineering-applications
#19
REVIEW
Nadeem Siddiqui, Simran Asawa, Bhaskar Birru, Ramaraju Baadhe, Sreenivasa Rao
Biomaterial-based scaffolds are important cues in tissue engineering (TE) applications. Recent advances in TE have led to the development of suitable scaffold architecture for various tissue defects. In this narrative review on polycaprolactone (PCL), we have discussed in detail about the synthesis of PCL, various properties and most recent advances of using PCL and PCL blended with either natural or synthetic polymers and ceramic materials for TE applications. Further, various forms of PCL scaffolds such as porous, films and fibrous have been discussed along with the stem cells and their sources employed in various tissue repair strategies...
May 14, 2018: Molecular Biotechnology
https://www.readbyqxmd.com/read/29758873/lost-but-can-t-be-neglected-huge-quantities-of-small-microplastics-hide-in-the-south-china-sea
#20
Minggang Cai, Haixia He, Mengyang Liu, Siwei Li, Guowen Tang, Weimin Wang, Peng Huang, Ge Wei, Yan Lin, Bin Chen, Jiahui Hu, Zhengnan Cen
Large quantities of microplastics with small particle sizes were found in the South China Sea (SCS). The abundances of microplastics in seawater were 0.045±0.093and 2569±1770particles/m3 according to the bongo net and pumping sampling methods, respectively. Smaller-size fractions (size<0.3mm) contributed 92% of the number of microplastics to the total load. Continental slope is the largest reservoir of microplastics with an inventory of 295tons. 21 polymer types were found in the samples using the micro Fourier Transform Infrared Spectroscopy (FTIR), among which alkyds (22...
August 15, 2018: Science of the Total Environment
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