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https://www.readbyqxmd.com/read/27591451/-male-contraception-the-current-state-of-knowledge
#1
REVIEW
Zygmynt Zdrojewicz, Karolina Kasperska, Marta Lewandowska
Contraception is important from a health, psychological and socioeconomic point of view. Due to the fact that male-based contraceptive methods are mostly represented by condoms and vasectomy, researchers are working on the new solutions, which could let the men be more involved in a conscious family planning. In this review we will present the current state of knowledge on this subject. There is a lot going on in the field of hormonal contraception. Studies including testosterone, progestins, synthetic androgens and other derivatives are on a different stages of clinical trials and mostly demonstrate high efficacy rates...
August 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27590656/-male-contraception-the-current-state-of-knowledge
#2
REVIEW
Zygmynt Zdrojewicz, Karolina Kasperska, Marta Lewandowska
Contraception is important from a health, psychological and socioeconomic point of view. Due to the fact that male-based contraceptive methods are mostly represented by condoms and vasectomy, researchers are working on the new solutions, which could let the men be more involved in a conscious family planning. In this review we will present the current state of knowledge on this subject. There is a lot going on in the field of hormonal contraception. Studies including testosterone, progestins, synthetic androgens and other derivatives are on a different stages of clinical trials and mostly demonstrate high efficacy rates...
July 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27540119/the-mayer-hashi-large-scale-program-to-increase-use-of-long-acting-reversible-contraceptives-and-permanent-methods-in-bangladesh-explaining-the-disappointing-results-an-outcome-and-process-evaluation
#3
Mizanur Rahman, M Moinuddin Haider, Sian L Curtis, Peter M Lance
BACKGROUND: Bangladesh has achieved a low total fertility rate of 2.3. Two-thirds of currently married women of reproductive age (CMWRA) want to limit fertility, and many women achieve their desired fertility before age 30. The incidence of unintended pregnancy and pregnancy termination is high, however. Long-acting reversible contraceptives (LARCs), consisting of the intrauterine device and implant, and permanent methods (PM), including female sterilization and vasectomy, offer several advantages in this situation, but only 8% of CMWRA or 13% of method users use these methods...
August 11, 2016: Global Health, Science and Practice
https://www.readbyqxmd.com/read/27134944/the-epidemiology-of-anti-sperm-antibodies-among-couples-with-unexplained-infertility-in-north-west-bank-palestine
#4
Anas Lotfi Yasin, Ahmad Lotfi Yasin, Walid Salim Basha
INTRODUCTION: Anti sperm antibodies (ASA) can present in serum and semen and they may lead to impair the sperms function leading to infertility. The precise mechanism of generation of these antibodies is yet to be discovered. AIM: This study was performed to determine the prevalence of anti-sperm antibodies (ASA) in patients with unexplained infertility. The study was initiated also to explore the possible factors that may associate with ASA formation and how ASA status is associated with pregnancy rates after going with in vitro fertilization - intracytoplasmic sperm injection (IVF-ICSI)...
March 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26748683/relative-suitability-of-dmso-and-nahco3-for-reversal-of-risug%C3%A2-induced-long-term-contraception
#5
A S Ansari, M Hussain, S R Khan, N K Lohiya
Among the vas-based methods on trial, reversible inhibition of sperm under guidance (RISUG(®) ), a co-polymer of styrene and maleic anhydride is being projected as an effective alternative to No Scalpel Vasectomy. RISUG offers long-term contraception with safety, efficacy in human trials and can be delivered by no-scalpel injection. Currently, the procedure is under phase-III clinical trial. However, reversal of this vas-based drug-induced contraception needs to be established in animal models prior to clinical trials to ensure its claim as an effective alternative for vasectomy...
March 2016: Andrology
https://www.readbyqxmd.com/read/26732151/male-contraception-a-clinically-oriented-review
#6
George A Kanakis, Dimitrios G Goulis
Despite the variety of available female contraceptive methods, many pregnancies (~50%) are still undesired. Many men (>60%) want to participate equally with their partner in family planning; however, male contraceptive methods (MCMs) account for only 14% of those used worldwide and no pharmaceutical MCM is available so far. The only two MCMs currently available are condoms, which despite protecting against sexually transmitted diseases have high failure rates (~19%), and vasectomy, which though very efficient (99%) is poorly reversible (<50%)...
October 2015: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/26165616/vasectomy-reversal-for-postvasectomy-pain-syndrome-a-study-and-literature-review
#7
REVIEW
A Scott Polackwich, Nicholas N Tadros, Kevin A Ostrowski, Joe Kent, Michael J Conlin, Jason C Hedges, Eugene F Fuchs
OBJECTIVE: To review our institution's experience and success with vasectomy reversal to treat postvasectomy pain syndrome (PVPS) over the last 20 years. MATERIALS AND METHODS: A single surgeon (E.F.F.) performed all the vasectomy reversals. We identified 123 procedures done for PVPS treatment and were able to contact 76 patients. We sent surveys or conducted phone interviews inquiring about satisfaction, levels of pain preoperatively and postoperatively, and the need for additional procedures for pain...
August 2015: Urology
https://www.readbyqxmd.com/read/25980804/the-evolution-of-vasectomy-reversal
#8
REVIEW
Ryan M Dickey, Alexander W Pastuszak, Tariq S Hakky, Aravind Chandrashekar, Ranjith Ramasamy, Larry I Lipshultz
In the USA, about 500,000 vasectomies are performed each year, with up to 6% of men requesting reversal. The technique of vasectomy reversal has evolved from macrosurgical to the implementation of both microscopic and robotic technologies. The very earliest attempts at vasectomy reversal, the vasoepididymostomy and vasovasostomy, have remained central in the treatment of male infertility and will continue to be so for years to come. As seen throughout its history, urological microsurgery has consistently implemented advanced techniques and state-of-the art technology in its craft, and its continued refinement will allow for even more favorable outcomes in the lives of patients seeking restoration of fertility following vasectomy...
June 2015: Current Urology Reports
https://www.readbyqxmd.com/read/25658225/male-contraception-past-present-and-future
#9
REVIEW
Christopher Payne, Erwin Goldberg
Current contraceptive options available to men include withdrawal, condoms, and vasectomy, each of which has its own drawbacks. In this chapter we will describe the pros and cons for each, as well as methodological and product updates. Statistics from the U.S. Centers for Disease Control on acceptance and satisfaction will be included. Advances in vasectomy and reversal will be presented. Methods to develop new contraceptive technologies fall into two categories: hormonal and non-hormonal. Many targets and strategies have been proposed for non-hormonal male contraception within the testis...
2014: Current Molecular Pharmacology
https://www.readbyqxmd.com/read/25595861/impact-on-pregnancy-of-gross-and-microscopic-vasal-fluid-during-vasectomy-reversal
#10
COMPARATIVE STUDY
Kevin A Ostrowski, A Scott Polackwich, Michael J Conlin, Jason C Hedges, Eugene F Fuchs
PURPOSE: We compared fertility outcomes with gross and microscopic fluid findings at vasectomy reversal at a high volume vasectomy reversal center. MATERIALS AND METHODS: A retrospective study of a prospective database was performed. All vasectomy reversals were performed by a single surgeon (EFF) between 1978 and 2011. The clinical pregnancy rate was self-reported or determined via patient mailers. Patient and operative findings were determined through database review...
July 2015: Journal of Urology
https://www.readbyqxmd.com/read/25088953/higher-outcomes-of-vasectomy-reversal-in-men-with-the-same-female-partner-as-before-vasectomy
#11
Kevin A Ostrowski, A Scott Polackwich, Joe Kent, Michael J Conlin, Jason C Hedges, Eugene F Fuchs
PURPOSE: We reviewed fertility outcomes of vasectomy reversal at a high surgical volume center in men with the same female partner as before vasectomy. MATERIALS AND METHODS: We retrospectively studied a prospective database. All vasectomy reversals were performed by a single surgeon (EFF). Patients who underwent microsurgical vasectomy reversal and had the same female partner as before vasectomy were identified from 1978 to 2011. Pregnancy and live birth rates, procedure type (bilateral vasovasostomy, bilateral vasoepididymostomy, unilateral vasovasostomy or unilateral vasoepididymostomy), patency rate, time from reversal and spouse age were evaluated...
January 2015: Journal of Urology
https://www.readbyqxmd.com/read/24990143/the-contraception-needs-of-the-perimenopausal-woman
#12
Sarah M R Hardman, Ailsa E Gebbie
Perimenopausal women have low fertility but must still be advised to use contraception until natural sterility is reached if they are sexually active. Patterns of contraceptive use vary in different countries worldwide. Long-acting reversible contraceptive methods offer reliable contraception that may be an alternative to sterilisation. Hormonal methods confer significant non-contraceptive benefits, and each individual woman should weigh up the benefits and risks of a particular method. No method of contraception is contraindicated by age alone, although combined hormonal contraception and injectable progestogens are not recommended for women over the age of 50 years...
August 2014: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/24951200/mri-of-the-epididymis-can-the-outcome-of-vasectomy-reversal-be-predicted-preoperatively
#13
Kevin C McCammack, Lejla Aganovic, Tung-Chin Hsieh, Yueyang Guo, Christian S Welch, Anthony C Gamst, Fiona Cassidy
OBJECTIVE: The purpose of this study is to describe the MRI findings seen with tubular ectasia of the epididymis and investigate whether MRI may predict vasal/epididymal tubular occlusion before vasectomy reversal. MATERIALS AND METHODS: First, we compared epididymal T1 signal intensity (measured as percentage change relative to ipsilateral testis) in 24 patients with sonographically established tubular ectasia compared with 22 control patients (sonographically normal epididymides)...
July 2014: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/24654689/importance-of-male-fertility-control-in-family-planning
#14
Daulat R P Tulsiani, Aida Abou-Haila
The world population, currently estimated to be almost seven billion, is expected to double in less than four decades. The projected population growth will cause severe competition for existing resources, not to mention the issue of overcrowding of the planet and additional greenhouse gases that will have an adverse effect on the ecological health of the planet. A recent survey conducted by the United Nations Population Control Division shows that the majority of today's young men in many countries are willing to participate in family planning by taking full control of their fertility, an important global health issue...
2014: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/24612756/analysis-of-international-practice-patterns-regarding-postvasectomy-fertility-options
#15
COMPARATIVE STUDY
Ola Blach, Anand N Shridharani, Jay I Sandlow
OBJECTIVE: To review the management of postvasectomy fertility options by urologists with vs without andrology fellowship and compare the features of practice in the USA vs UK. MATERIALS AND METHODS: We conducted an audit of all American Urological Association-affiliated urologists regarding their practice in managing men requesting vasectomy reversal (VR). Standards of practice were assessed against 10 index parameters deemed, by 1 UK study, to reflect best practice...
May 2014: Urology
https://www.readbyqxmd.com/read/24437091/applying-clinically-proven-human-techniques-for-contraception-and-fertility-to-endangered-species-and-zoo-animals-a-review
#16
REVIEW
Sherman J Silber, Natalie Barbey, Kathy Lenahan, David Z Silber
Reversible contraception that does not alter natural behavior is a critical need for managing zoo populations. In addition to reversible contraception, other fertility techniques perfected in humans may be useful, such as in vitro fertilization (IVF) or oocyte and embryo banking for endangered species like amphibians and Mexican wolves (Canis lupus baileyi). Furthermore, the genetics of human fertility can give a better understanding of fertility in more exotic species. Collaborations were established to apply human fertility techniques to the captive population...
December 2013: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/23922817/sperm-recovery-and-ivf-after-testicular-sperm-extraction-tese-effect-of-male-diagnosis-and-use-of-off-site-surgical-centers-on-sperm-recovery-and-ivf
#17
Kenan Omurtag, Amber Cooper, Arnold Bullock, Cathy Naughton, Valerie Ratts, Randall Odem, Susan E Lanzendorf
OBJECTIVE: Determine whether testicular sperm extractions and pregnancy outcomes are influenced by male and female infertility diagnoses, location of surgical center and time to cryopreservation. PATIENTS: One hundred and thirty men undergoing testicular sperm extraction and 76 couples undergoing 123 in vitro fertilization cycles with testicular sperm. OUTCOME MEASURES: Successful sperm recovery defined as 1-2 sperm/0.5 mL by diagnosis including obstructive azoospermia (n = 60), non-obstructive azoospermia (n = 39), cancer (n = 14), paralysis (n = 7) and other (n = 10)...
2013: PloS One
https://www.readbyqxmd.com/read/23596597/advances-in-surgical-treatment-of-male-infertility
#18
Hyo Serk Lee, Ju Tae Seo
A male factor is the only cause of infertility in 30% to 40% of couples. Most causes of male infertility are treatable, and the goal of many treatments is to restore the ability to conceive naturally. Varicoceles are present in 15% of the normal male population and in approximately 40% of men with infertility. Varicocele is the most common cause of male infertility that can be corrected surgically. In males with azoospermia, the most common cause is post-vasectomy status. Approximately 6% of males who undergo vasectomy eventually seek reversal surgery...
August 2012: World Journal of Men's Health
https://www.readbyqxmd.com/read/23569082/what-is-the-best-cryopreservation-protocol-for-human-testicular-tissue-banking
#19
Y Baert, D Van Saen, P Haentjens, P In't Veld, H Tournaye, E Goossens
STUDY QUESTION: Is there a better alternative to the conventional cryopreservation protocols for human testicular tissue banking? SUMMARY ANSWER: Uncontrolled slow freezing (USF) using 1.5 M dimethylsulphoxide (DMSO) and 0.15 M sucrose as cryoprotectants appears to be a user-friendly and efficient method for the cryopreservation of human testicular tissue. WHAT IS KNOWN ALREADY: Currently, time-consuming controlled slow freezing (CSF) protocols that need expensive equipment are commonly used for human testicular tissue banking...
July 2013: Human Reproduction
https://www.readbyqxmd.com/read/23539611/microrna-signature-is-altered-in-both-human-epididymis-and-seminal-microvesicles-following-vasectomy
#20
Clémence Belleannée, Christine Légaré, Ezéquiel Calvo, Véronique Thimon, Robert Sullivan
STUDY QUESTION: Does vasectomy impact microRNA (miRNA) expression in the epididymis and seminal microvesicles (SMVs) in a non-reversible manner? SUMMARY ANSWER: The miRNA signature in the epididymis and SMVs is altered by vasectomy and only partially restored after vasovasostomy surgery. WHAT IS KNOWN ALREADY: Vasectomy modifies the epididymal transcriptome and triggers non-reversible changes that affect sperm function. Some vasovasostomized men experience a reduced fertility outcome...
June 2013: Human Reproduction
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