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tumor associated macrophagy

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https://www.readbyqxmd.com/read/25992444/pulmonary-multifunctional-nano-oncological-modules-for-lung-cancer-treatment-and-prevention
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REVIEW
Harshad K Shete, Swati S Vyas, Vandana B Patravale, John I Disouza
Mortality associated with lung cancer and its metastasis has outnumbered those related to other forms of cancer. Despite being a directly accessible organ, conventional oncological strategies exhibiting prolific outcome in treatment and prevention of lung cancer is far from reality. This is attributed to numerous challenges posed by lung environment. The extracellular aura of lung comprises immensely complicated structures, ciliary escalators, omnipresence of mucus and alveolar fluid, and macrophagial uptake which presents an array of impediments to the arrival of therapeutic moiety at the tumor site...
September 2014: Journal of Biomedical Nanotechnology
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