keyword
https://read.qxmd.com/read/38444374/lipoaspirate-injection-in-relapsing-idiopathic-subglottic-stenosis-preliminary-results
#1
JOURNAL ARTICLE
Francesco Mattioli, Edoardo Serafini, Alessandro Andreani, Gaia Cappiello, Federico De Maria, Daniele Marchioni, Massimo Pinelli, Alessandro Marchioni
OBJECTIVES: The management of idiopathic subglottic stenosis (iSGS) poses a clinical challenge due to high recurrence rates following both endoscopic and open approaches, often leading to tracheostomy. The activation of abnormal T-cells and cytokine pathways has been linked to iSGS pathogenesis. Autologous adipose tissue centrifugation yields lipoaspirate, offering optimal anti-inflammatory effects and biocompatibility widely utilized in various medical settings. This report presents the first 3 cases employing endoscopic dilation (ED) in combination with local lipoaspirate injection to address recurrent iSGS...
March 6, 2024: Annals of Otology, Rhinology, and Laryngology
https://read.qxmd.com/read/38441273/outcomes-of-not-using-tracheoplasty-in-asymptomatic-tracheal-stenosis-found-during-open-heart-surgery
#2
JOURNAL ARTICLE
Seon Yong Bae, Jae Hong Lee, Hye Won Kwon, Sungkyu Cho, Chiheon Kwon, Woong-Han Kim, Jae Gun Kwak
OBJECTIVES: We aimed to review the outcomes of treating incidentally encountered asymptomatic airway stenosis during open-heart surgery conservatively without the use of tracheoplasty. METHODS: Between January 2002 and October 2022, 25 patients were incidentally diagnosed with tracheal stenosis during open-heart surgery. Intraoperative bronchoscopy and/or laryngoscopy revealed tracheal stenosis; however, this was not consistent with the findings of the preoperative computed tomography...
March 5, 2024: Interdiscip Cardiovasc Thorac Surg
https://read.qxmd.com/read/38439622/a-clinical-study-on-video-bronchoscopy-guided-coblation-for-benign-central-airway-stenosis
#3
JOURNAL ARTICLE
Haitao Li, Xuezhu Ren, Haizhong Zhang, Shuai Li, Yuzheng He, Tianjie Qi, Zhigang Cai
Background: Benign central airway stenosis poses a significant challenge to respiratory and thoracic surgeons due to the high recurrence rate associated with current treatment methods, causing severe breathing difficulties and potentially life-threatening complications. This article aims to investigate the therapeutic efficacy and prospects of using coblation in the management of benign central airway stenosis in adults. Moreover, the pathogenesis of benign central airway stenosis was deeply explored to provide better guidance for future clinical treatments...
March 4, 2024: Ear, Nose, & Throat Journal
https://read.qxmd.com/read/38401643/the-mobility-of-the-brachycephalic-canine-nostril-in-relation-to-the-degree-of-nostril-stenosis
#4
JOURNAL ARTICLE
C A T Sharp, N-C Liu, A Guy, J F Ladlow
Previous studies have shown that the most reliable external conformational risk factor of whether a brachycephalic dog will develop Brachycephalic Obstructive Airway Syndrome (BOAS) is the status of nostril stenosis, assessed as a static observation using the brachycephalic nostril grading scheme. The nostrils however are a dynamic structure, opening further when the dog is exercising, sniffing or panting. The hypothesis of this study was that brachycephalic dogs with open or mildly stenotic nostrils are more likely to have nostril mobility whilst dogs with moderately or severely stenotic nostrils are more likely to have immobile nostrils...
February 22, 2024: Veterinary Journal
https://read.qxmd.com/read/38322442/site-of-tracheostomy-and-its-influence-on-the-surgical-outcome-and-quality-of-life-after-tracheal-resection-and-anastomosis-in-patients-with-tracheal-stenosis
#5
JOURNAL ARTICLE
Soorya Pradeep, Arun Alexander, Sivaraman Ganesan, Dharanya Gopalakrishnan Srinivasan, Akshat Kushwaha, Aparna Gopalakrishnan, Lokesh Kumar Penubarthi, Kalaiarasi Raja, Sunil Kumar Saxena
Introduction  With the advances in critical care, the incidence of post intubation tracheal stenosis is increasing. Tracheal resection and anastomosis have been the gold standard for the management of grades III and IV stenosis. Scientific evidence from the literature on the determining factors and outcomes of surgery is not well described. Objective  This study was aimed at determining the influence of tracheostoma site on the surgical outcomes and postoperative quality of life of patients undergoing tracheal resection anastomosis...
January 2024: International Archives of Otorhinolaryngology
https://read.qxmd.com/read/38233186/risk-factors-for-desaturation-in-anesthetic-management-during-airway-stenting
#6
JOURNAL ARTICLE
Sakura Okamoto, Namie Somiya, Ran Hotta, Hideo Saka, Masahide Oki, Akira Tomita
Airway stenting involves a stent being inserted into a stenotic site in the airway. In patients with airway stenosis, the airway is the surgical field; therefore, anesthetic management is challenging, and avoiding hypoxia is important. Limited information is available on the anesthetic management of airway stenting. Risk factors for oxygen desaturation during airway stenting remain unknown. The present study was conducted to retrospectively examine patients who underwent airway stenting during a specific period and identify risk factors associated with oxygen desaturation...
January 16, 2024: Kurume Medical Journal
https://read.qxmd.com/read/38123324/management-of-post-traumatic-tracheal-stenosis-with-silicone-stent-placement
#7
JOURNAL ARTICLE
Prakash Sivaramakrishnan, Mayank Mishra, Girish Sindhwani
Benign airway stenosis often poses a therapeutic challenge and requires a multidisciplinary approach involving interventional pulmonologists and thoracic surgeons. We report the case of a man who presented with thoracic trauma following a road traffic accident. His chest X-ray showed complete collapse of the right lung, while screening flexible bronchoscopy revealed pooled secretions and asymmetric mid-to-lower tracheal stenosis. After thorough clinicoradiological evaluation and multidisciplinary discussion, we proceeded with therapeutic rigid bronchoscopy and silicone stenting of the tracheal stenotic lesion...
December 20, 2023: BMJ Case Reports
https://read.qxmd.com/read/37897212/surgical-correction-of-stenotic-nares-using-a-single-pedicle-advancement-flap-technique-in-three-brachycephalic-cats
#8
Negin Rahimdoust Mozhdehi, Hamideh Salari Sedigh, Hossein Kazemi Mehrjerdi
Brachycephalic obstructive airway syndrome (BOAS) comprises a group of anatomical upper respiratory tract abnormalities that collectively result in various degrees of upper respiratory tract obstruction. Stenotic nares is a common feature of BOAS, and in dogs, the main cause is axial deviation of the alar cartilage. In contrast, narrowing of the nares in cats is predominantly the result of a redundant skin fold at the junction of the ventral floor of the nostrils and the haired skin of the lip. Three brachycephalic cats with inspiratory obstruction were referred to the surgery department of the Veterinary Teaching Hospital of Ferdowsi University of Mashhad, Iran...
October 28, 2023: Veterinary Medicine and Science
https://read.qxmd.com/read/37842865/a-novel-surgical-approach-for-feline-stenotic-nares-bilateral-wedge-resection-of-the-dorsal-lateral-nasal-cartilage-in-seven-cases
#9
JOURNAL ARTICLE
Yen-Chen Chen, Yun-Shun Chang
OBJECTIVE: Surgical correction of stenotic nares, one component of brachycephalic obstructive airway syndrome (BOAS), is not referenced as often in cats as it is in dogs. Similar to dogs, stenotic nares emerge as a significant contributor in the development of BOAS in cats. In this study, we propose that stenotic nares in brachycephalic cats arise from an elongated dorsal lateral nasal cartilage. The aim of this paper is to illustrate a novel surgical technique to alleviate stenosis-associated clinical signs by performing full-thickness bilateral wedge resection of the excessive cartilage...
October 16, 2023: Veterinary Medicine and Science
https://read.qxmd.com/read/37814310/comparison-of-the-effectiveness-of-three-different-rhinoplasty-techniques-to-correct-stenotic-nostrils-using-silicone-models-a-case-study
#10
JOURNAL ARTICLE
Phil H Franklin, Julia Riggs, Nai-Chieh Liu
OBJECTIVE: To compare the effects of three different rhinoplasty techniques on the postoperative cross-sectional areas (CSAs) of the nares and nasal vestibuli. STUDY DESIGN: Experimental study. SAMPLE POPULATION: Ninety-nine 3D-printed, remolded silicone models of a single French bulldog's rostral nose. METHODS: Models were fabricated based on a computed tomographic (CT) scan of the nose of a French bulldog with moderately stenotic nares...
January 2024: Veterinary Surgery
https://read.qxmd.com/read/37804518/autologous-airway-basal-cell-transplantation-alleviates-airway-epithelium-defect-in-recurrent-benign-tracheal-stenosis
#11
JOURNAL ARTICLE
Yong-Shun Ye, Di-Fei Chen, Ming Liu, Yu-Long Luo, Huan-Jie Chen, Hai-Kang Zeng, Jing-Wei Liu, Yi-Ping Zhu, Xin-Yu Song, Chang-Qin Lin, Zhu-Quan Su, Shi-Yue Li
BACKGROUND: Airway epithelium defects are a hallmark of recurrent benign tracheal stenosis (RBTS). Reconstructing an intact airway epithelium is of great importance in airway homeostasis and epithelial wound healing and has great potential for treating tracheal stenosis. METHODS: An experimental study was conducted in canines to explore the therapeutic effect of autologous basal cell transplantation in restoring airway homeostasis. First, airway mucosae from human patients with recurrent tracheal stenosis were analyzed by single-cell RNA sequencing...
October 7, 2023: Stem Cells Translational Medicine
https://read.qxmd.com/read/37733404/outcomes-of-holmium-laser-cryoablation-and-budesonide-inhalation-for-treating-severe-central-airway-stenosis-in-infants
#12
JOURNAL ARTICLE
Lei Zhang, Shuhua Yuan, Chunhong Pan, Jing Zhang, Jinhong Wu, Yong Yin
BACKGROUND: Central airway stenosis (CAS) in infants is characterized by dysphonia, dyspnea, cyanosis, repeated apnea, and infection. This case series study aimed to evaluate the safety and efficacy of holmium laser, cryoablation and budesonide inhalation in treating infants with severe CAS. METHODS: This retrospective study reviewed medical records data of 28 infants with severe CAS who underwent holmium laser treatment with cryoablation and/or balloon dilatation and budesonide inhalation therapy at Shanghai Children's Medical Center between June 2014 and May 2020...
December 2023: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://read.qxmd.com/read/37573642/stenotic-geometry-effects-on-airflow-dynamics-and-respiration-for-central-airway-obstruction
#13
JOURNAL ARTICLE
Ming Ding, Jing Ning, Xiuyan Liu, Runze Mi, Yan Cai
BACKGROUND AND OBJECTIVE: The quantitative relationship between tracheal anatomy and ventilation function can be analyzed by using engineering-derived methods, including mathematical modeling and numerical simulations. In order to provide quantitative functional evaluation for patients with tracheobronchial stenosis, we here propose an aerodynamics-based assessment method by applying computational fluid dynamics analysis on synthetic and patient-specific airway models. METHODS: By using 3D reconstruction of tracheobronchial tree and computational fluid dynamics simulations, the aerodynamic environment from the stenotic central airway down to the 4th-6th bifurcation of the tracheobronchial tree is examined in both synthetic and patient-derived models...
August 9, 2023: Computer Methods and Programs in Biomedicine
https://read.qxmd.com/read/37458368/modulated-fibrosis-and-mechanosensing-of-fibroblasts-by-sb525334-in-pediatric-subglottic-stenosis
#14
JOURNAL ARTICLE
Soheila Ali Akbari Ghavimi, Matthew R Aronson, Daniel D Ghaderi, Ryan M Friedman, Neil Patel, Terri Giordano, Ryan C Borek, Conor M Devine, Lin Han, Ian N Jacobs, Riccardo Gottardi
OBJECTIVE: Subglottic stenosis (SGS) may result from prolonged intubation where fibrotic scar tissue narrows the airway. The scar forms by differentiated myofibroblasts secreting excessive extracellular matrix (ECM). TGF-β1 is widely accepted as a regulator of fibrosis; however, it is unclear how biomechanical pathways co-regulate fibrosis. Therefore, we phenotyped fibroblasts from pediatric patients with SGS to explore how key signaling pathways, TGF-β and Hippo, impact scarring and assess the impact of inhibiting these pathways with potential therapeutic small molecules SB525334 and DRD1 agonist dihydrexidine hydrochloride (DHX)...
July 17, 2023: Laryngoscope
https://read.qxmd.com/read/37335600/comparative-histological-analysis-of-the-alae-nasi-in-french-bulldogs-with-brachycephalic-obstructive-airway-syndrome-and-unaffected-non-brachycephalic-dogs
#15
JOURNAL ARTICLE
Fabrizio di Virgilio, Vivien Guelette, Daniela Prata, Lilia Boulouha, Marisa Santos, Elena Belluzzi, Johan Caraty, Alexandre Bongartz, Aymeric Deneuche
BACKGROUND: Brachycephalic dogs are characterised by a short and flat nose. This cranial conformation is associated with brachycephalic obstructive airway syndrome, a respiratory syndrome primarily characterised by stenotic nares, a hyperplastic soft palate and a hypoplastic trachea, among other malformations, with secondary abnormalities resulting in upper airway obstruction METHODS: In this study, we aimed to characterise and compare the histological features of tissue samples harvested from the alae nasi of French bulldogs and non-brachycephalic dogs...
June 19, 2023: Veterinary Record
https://read.qxmd.com/read/37308350/comparison-of-single-coronal-thick-slab-minimum-intensity-projection-with-flexible-bronchoscopy-for-airway-compression-in-children-with-lymphobronchial-tuberculosis
#16
JOURNAL ARTICLE
S S B Venkatakrishna, A O A Krim, J Calle-Toro, S Lucas, D Bester, P Goussard, S Andronikou
AIM: To generate standardised coronal minimum intensity projection (MinIP) computed tomography (CT) reconstructions, and compare these with flexible bronchoscopy in children with lymphobronchial tuberculosis (LBTB). MATERIALS AND METHODS: Standardised coronal MinIP reconstructions were performed from CT images in children with LBTB and the findings of three readers were compared with the reference standard, flexible bronchoscopy (FB), regarding airway narrowing...
May 13, 2023: Clinical Radiology
https://read.qxmd.com/read/37305073/a-computational-analysis-on-the-impact-of-multilevel-laryngotracheal-stenosis-on-airflow-and-drug-particle-dynamics-in-the-upper-airway
#17
JOURNAL ARTICLE
Raluca E Gosman, Ryan M Sicard, Seth M Cohen, Dennis O Frank-Ito
Laryngotracheal stenosis (LTS) is a type of airway narrowing that is frequently caused by intubation-related trauma. LTS can occur at one or multiple locations in the larynx and/or trachea. This study characterizes airflow dynamics and drug delivery in patients with multilevel stenosis. Two subjects with multilevel stenosis (S1 = glottis + trachea, S2 = glottis + subglottis) and one normal subject were retrospectively selected. Computed tomography scans were used to create subject-specific upper airway models...
2023: Experimental and computational multiphase flow
https://read.qxmd.com/read/37275098/a-prospective-institutional-study-on-aetiopathogenesis-management-and-complications-of-laryngotracheal-stenosis
#18
JOURNAL ARTICLE
Sourabh Padmanabhan, Ranganath Swamy, Shobhan Babu, Y Mounika Reddy, Naresh Mogilicharla
The main purpose of this study is to evaluate and understand the clinical profile of patients presenting to an Indian tertiary care referral centre with Laryngotracheal Stenosis (LTS) and also to emphasise on the outcomes after treatment in these patients. This is a prospective observational study conducted at a tertiary care referral centre which included 18 patients diagnosed with LTS. All patients were evaluated clinically and radiologically to evaluate the degree of stenosis, site and length of the stenotic segment involved, intervened surgical procedure, intraoperative and postoperative complications following the procedure were all documented and taken into consideration...
June 2023: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/37194663/utilizing-a-functional-lumen-imaging-probe-for-evaluation-of-the-pediatric-airway-a-pilot-study
#19
JOURNAL ARTICLE
Sarek A Shen, Andy S Ding, Jared Zhao, Stefanie Seo, Kenneth Ng, Jonathan Walsh
OBJECTIVES: Accurate and reproducible measurements of the pediatric airway are critical for diagnostic evaluation and management of subglottic and tracheal stenosis. The endoluminal functional lumen imaging probe (EndoFLIP) is a catheter-based imaging probe which utilizes impedance planimetry to calculate luminal parameters, including cross-sectional area and compliance. Herein, we demonstrate the feasibility of this system for multidimensional evaluation of the pediatric airway. METHODS: 3D-printed pediatric laryngotracheal models were created based on computed tomography scans, then artificially deformed to simulate both circumferential and posterior subglottic stenosis...
May 17, 2023: Laryngoscope
https://read.qxmd.com/read/37007876/laryngotracheal-stenosis-our-experience-in-a-tertiary-care-hospital
#20
JOURNAL ARTICLE
Achal Pandya, S R Sreevidya, Nirav Chaudhari, Bela J Prajapati, Nandini Gupta
Laryngotracheal stenosis is a recalcitrant disease with high morbidity. Laryngotracheal stenosis can be defined as a partial or circumferential narrowing of the airway and may be congenital or acquired. Sites involved are supraglottis, glottis, or sub glottis. The goal of treating the patient with laryngotracheal stenosis is to reconstruct an adequate airway while preserving phonation and airway protection. Furthermore, there is no fixed treatment for laryngotracheal stenosis, the choice of surgical procedure is determined by the individual anatomy, involved site, length and luminal narrowing of stenotic segment and function of the larynx and trachea, together with patient factors and available facilities...
March 2023: Indian Journal of Otolaryngology and Head and Neck Surgery
keyword
keyword
90731
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.