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https://www.readbyqxmd.com/read/28342392/value-of-the-68-ga-dotatate-pet-ct-in-the-diagnosis-of-endometriosis-a-pilot-study
#1
M Fastrez, C Artigas, N Sirtaine, Z Wimana, M Caillet, S Rozenberg, P Flamen
OBJECTIVE: The non-invasive diagnosis of endometriosis remains challenging. Recent data suggested that somatostatin might be involved in its pathogenesis. High sensitive visualization of somatostatin receptors expression is possible using PET-CT imaging after the administration of a (68)Ga-labeled somatostatin analog (DOTATATE) that will bind to the somatostatin receptor sub-types 2 and 5. The aim of the present study was to assess the usefulness of (68)Ga-DOTATATE PET-CT in the diagnosis of endometriosis...
March 16, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28288139/mice-deleted-for-cell-division-cycle-73-gene-develop-parathyroid-and-uterine-tumours-model-for-the-hyperparathyroidism-jaw-tumour-syndrome
#2
G V Walls, M Stevenson, K E Lines, P J Newey, A A C Reed, M R Bowl, J Jeyabalan, B Harding, K J Bradley, S Manek, J Chen, P Wang, B O Williams, B T Teh, R V Thakker
The hyperparathyroidism-jaw tumour (HPT-JT) syndrome is an autosomal dominant disorder characterized by occurrence of parathyroid tumours, often atypical adenomas and carcinomas, ossifying jaw fibromas, renal tumours and uterine benign and malignant neoplasms. HPT-JT is caused by mutations of the cell division cycle 73 (CDC73) gene, located on chromosome 1q31.2 and encodes a 531 amino acid protein, parafibromin. To facilitate in vivo studies of Cdc73 in tumourigenesis we generated conventional (Cdc73(+/-)) and conditional parathyroid-specific (Cdc73(+/L)/PTH-Cre and Cdc73(L/L)/PTH-Cre) mouse models...
March 13, 2017: Oncogene
https://www.readbyqxmd.com/read/28248886/endoscopic-submucosal-dissection-for-gastric-adenomyoma-a-rare-entity-of-15-cases-among-571-patients-with-gastric-submucosal-eminence-lesions
#3
Sinan Wang, Hailong Cao, Yujie Zhang, Mengque Xu, Xue Chen, Meiyu Piao, Bangmao Wang
Gastric adenomyoma (GA) is a kind of rare gastric submucosal eminence lesions. As the malignant transformation cannot be ruled out, surgery and laparoscopic resection are usually considered. The aim of this study is to evaluate the therapeutic effect and safety of endoscopic submucosal dissection (ESD) for GA.All of the patients with gastric submucosal eminence lesions who underwent ESD from June 2008 to June 2015 in General Hospital, Tianjin Medical University, China, were identified, and patients with GA, which was confirmed by pathological evaluation, were enrolled for further analysis...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28197875/mri-us-or-real-time-virtual-sonography-in-the-evaluation-of-adenomyosis
#4
Valeria Vinci, Matteo Saldari, Maria Eleonora Sergi, Silvia Bernardo, Giuseppe Rizzo, Maria Grazia Porpora, Carlo Catalano, Lucia Manganaro
PURPOSE: Real-time virtual sonography (RVS) allows displaying and synchronizing real-time US and multiplanar reconstruction of MRI images. The purpose of this study was to evaluate the feasibility and ability of RVS to assess adenomyosis since literature shows US itself has a reduced diagnostic accuracy compared to MRI. MATERIALS AND METHODS: This study was conducted over a 4-month period (March-June 2015). We enrolled in the study 52 women with clinical symptoms of dysmenorrhea, methrorragia and infertility...
February 15, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28160434/cytological-features-of-atypical-polypoid-adenomyoma-of-the-endometrium-a-case-report-with-literature-review
#5
Yusuke Ebisu, Tomoko Arimoto, Mitsuaki Ishida, Chika Miyasaka, Yoshiko Uemura, Hidetaka Okada, Koji Tsuta
Atypical polypoid adenomyoma (APA) is a rare mixed epithelial and mesenchymal tumor characterized histopathologically by the presence of disorganized hyperplastic glands with cytological atypia embedded in intersecting fascicles of fibromuscular stromal cells. Herein, we report the first documented endometrial cytological case of APA. A 35-year-old Japanese female presented with irregular menstrual cycles and then was found to have polypoid lesions of the endometrium. Cytological examination of the endometrium and endometrial curettage were performed...
April 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28002623/comprehensive-screening-for-med12-mutations-in-gynecological-mesenchymal-tumors-identified-morphologically-distinctive-mixed-epithelial-and-stromal-tumors
#6
Chang-Tsu Yuan, Wen-Chih Huang, Cheng-Han Lee, Ming-Chieh Lin, Chen-Hui Lee, Yu-Chien Kao, Hsuan-Ying Huang, Kuan-Ting Kuo, Jen-Chieh Lee
BACKGROUND: MED12 exon 2 mutations have been identified in most uterine leiomyomas and mammary fibroepithelial tumors. MED12 has not been genotyped in most other gynecological mesenchymal tumors. DESIGN: 68 uncommon gynecological mesenchymal tumors were genotyped for MED12 exon 2, including 27 müllerian adenosarcomas (including 3 tentatively diagnosed as "variant adenosarcomas"), 6 cellular angiofibromas, 6 aggressive angiomyxomas, 5 angiomyofibroblastomas, 5 superficial myofibroblastomas, 5 atypical polypoid adenomyomas, and 14 endometrial stromal sarcomas...
December 21, 2016: Histopathology
https://www.readbyqxmd.com/read/27922981/second-opinion-expert-pathology-in-endometrial-cancer-potential-clinical-implications
#7
Friederike Grevenkamp, Felix Kommoss, Friedrich Kommoss, Sigurd Lax, Falko Fend, Diethelm Wallwiener, Birgitt Schönfisch, Bernhard Krämer, Sara Y Brucker, Florin-Andrei Taran, Annette Staebler, Stefan Kommoss
OBJECTIVE: In cancer patients, the pathology report serves as an important basis for treatment. Therefore, a correct cancer diagnosis is crucial, and diagnostic discrepancies may be of clinical relevance. It was the aim of this study to perform a specialized histopathology review and to investigate potential clinical implications of expert second opinion pathology in endometrial cancer. METHODS: Patients treated for endometrial carcinoma at the Tübingen University Women's hospital between 2003 and 2013 were identified...
February 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27775311/-infantile-hypertrofic-pyloric-stenosis-or-gastric-adenomyoma-differential-diagnosis-of-gastric-outlet-obstruction-in-children
#8
M Oviedo Gutiérrez, S Amat Valero, A Gómez Farpón, C Montalvo Ávalos, L Fernández García, D C Lara Cárdenas, S Barnes Marañón, C Granell Suárez, N Vega Mata, A J López López, M González Guerrero, V Álvarez Muñoz
PURPOSE: Gastrointestinal adenomyoma is a rare benign tumor most frequently located in the stomach. The differential diagnosis is wide because of its large clinical spectrum and unspecific radiological findings. Surgical excision is both diagnostic and therapeutic. CASE REPORT: A 49-days old girl presented with nonbilious vomiting of 48 hours of evolution. Infantile hypertrofic pyloric stenosis was suspected. Ultrasound showed a nonobstructive nodular lesion in the anterior pyloric wall...
July 20, 2015: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/27681950/-pitfalls-in-the-histopathological-diagnostics-of-endometrial-carcinoma-and-its-precursors-clinically-relevant-differential-diagnoses-avoidance-of-false-positive-diagnoses
#9
F Kommoss, S F Lax
Making an incorrect histopathological diagnosis of an endometrial lesion may lead to unwanted loss of fertility and therapy-associated morbidity; therefore, endometrial carcinomas need to be correctly typed and differentiated from hyperplastic precursors, benign lesions and artifacts. Typical diagnostic pitfalls are described in this article. Misdiagnosing endometrial lesions can be avoided by paying thorough attention to gross as well as microscopic features and by taking crucial differential diagnoses into consideration...
November 2016: Der Pathologe
https://www.readbyqxmd.com/read/27678779/laparoscopic-management-of-juvenile-cystic-adenomyoma
#10
E G Pabuccu, M Seval, M Sonmezer, C Atabekoglu
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27647499/ep27-09-pelvic-adenomyoma-eleven-years-after-total-hysterectomy-rare-report-and-literature-review
#11
M D Bernardo, A Bello, J Faria, F Sousa
No abstract text is available yet for this article.
September 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27593887/robot-assisted-laparoscopic-adenomyomectomy-for-patients-who-want-to-preserve-fertility
#12
Youn Jee Chung, So Yeon Kang, Mi Rang Choi, Hyun Hee Cho, Jang Heub Kim, Mee Ran Kim
An adenomyomectomy is a conservative-surgical option for preserving fertility. Conventional laparoscopic adenomyomectomies present difficulties in adenomyoma removal and suturing of the remaining myometrium. Robot-assisted laparoscopic surgery could overcome the limitations of conventional laparoscopic surgery. Four patients with severe secondary dysmenorrhea and pelvic pain visited Seoul St. Mary's Hospital and were diagnosed with adenomyosis by pelvic ultrasonography and pelvic magnetic resonance imaging (MRI)...
November 2016: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27582582/the-role-of-adenomyosis-in-the-pathogenesis-of-preeclampsia
#13
P S Hasdemir, M Farasat, C Aydin, B C Ozyurt, T Guvenal, G Pekindil
INTRODUCTION: Adenomyosis can cause defective deep placentation. Preeclampsia is known to be associated with abnormal placentation. The aim of this study was to compare the presence of adenomyosis on magnetic resonance imaging in patients with and without history of preeclampsia in order to investigate the possible role of adenomyosis in the pathogenesis of preeclampsia. MATERIALS AND METHODS: This prospective, randomized study consisted of patients with (n = 35) and without (n = 34) history of preeclampsia...
August 2016: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/27509468/adenomyoma-of-the-common-bile-duct-a-rare-lesion-diagnosed-and-treated-by-ercp
#14
Marco A D'Assuncao, Saverio T N Armellini, Daniel Moribe, Lucas S Nova da Costa, Gisele F C Leite, Larissa M Vendrame, Andre L Montagnini
No abstract text is available yet for this article.
2016: Endoscopy
https://www.readbyqxmd.com/read/27208606/parasitic-myomas-and-an-adenomyoma-obstructing-the-ureter-after-power-morcellation-of-myomas-and-endometriotic-nodule-resection
#15
Bulent Urman, Baris Ata, Tonguc Arslan, Sertan Aksu, Cagatay Taskiran
BACKGROUND: The use of power morcellation (PM) in abdominal and pelvic surgery has been discouraged and even banned in some institutions because of the risk of spreading malignant cells, although some authorities maintain that PM can be an appropriate tool for selected patients deemed to be at low risk of malignancy. CASE: A 42-year-old woman developed parasitic myomas and an adenomyoma obstructing the right ureter after laparoscopic excision of multiple myomas and deep infiltrating endometriosis using PM...
April 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/27147800/the-significance-of-mri-evaluation-of-the-uterine-junctional-zone-in-the-early-diagnosis-of-adenomyosis
#16
Amela Sofic, Azra Husic-Selimovic, Aladin Carovac, Elma Jahic, Velda Smailbegovic, Jana Kupusovic
GOAL: The aim of the study is to define the MRI appearance of disorder in the Junctional zone (JZ) in women with adenomyosis compared to those without it, given the importance of the JZ in the regulation of various reproductive events. MATERIALS AND METHODS: This was a prospective, comparative and open study. Patients with adenomyosis have been sorted in target group, n = 82, while the control group consisted of patients without adenomyosis, n = 82. All patients, from both groups have undergone a magnetic resonance imaging of the pelvis...
April 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/27134711/positron-emission-tomography-findings-in-atypical-polypoid-adenomyoma
#17
Tatsuya Fukami, Tomonori Yoshikai, Hiroshi Tsujioka, Atsushi Tohyama, Sumire Sorano, Sakiko Matsuoka, Hiroko Yamamoto, Sumie Nakamura, Maki Goto, Ryoei Matsuoka, Masafumi Oya, Yoshikuni Torii, Fuyuki Eguchi
Atypical polypoid adenomyoma (APAM) is a rare polypoid tumor of the uterus composed of atypical endometrial glands surrounded by smooth muscle. A 29-year-old nulligravida, was clinically diagnosed with endocervical myoma and underwent trans-uterine cervical resection with hysteroscope. The histopathological diagnosis of specimens was APAM. Eight months later, she diagnosed recurrent uterine tumor. The positron emission tomography (PET-CT) imaging showed an increased fluorodeoxyglucose uptake. She has performed hysterectomy and was diagnosed APAM...
March 21, 2016: Rare Tumors
https://www.readbyqxmd.com/read/26952349/comparison-of-classic-terminology-with-the-figo-palm-coein-system-for-classification-of-the-underlying-causes-of-abnormal-uterine-bleeding
#18
Emrah Töz, Muzaffer Sancı, Aykut Özcan, Emrah Beyan, Abdurrahman H İnan
OBJECTIVE: To compare classic terminology and the PALM-COEIN (polyp, adenomyosis, leiomyoma, malignancy and hyperplasia, coagulopathy, ovulatory disorders, endometrium, iatrogenic, and not classified) classification system among women who underwent surgery for abnormal uterine bleeding (AUB), and to subclassify the components of the PALM group for future studies. METHODS: In a retrospective study, data were obtained for nonpregnant women aged 18-55years who underwent hysterectomy, myomectomy, or polypectomy for AUB at a center in Turkey in 2014...
June 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/26837724/-gastric-adenomyoma-clinically-simulating-hypertrophic-pyloric-stenosis
#19
S Sánchez García, D Rubio Solís, G Anes González, S González Sánchez
Gastric adenomyomas are extremely uncommon benign tumors in children. On histologic examination, these tumors have an epithelial component similar to pancreatic ducts. We present a case of a pyloric adenomyoma that clinically simulated hypertrophic pyloric stenosis in a newborn girl. Imaging tests, fundamentally magnetic resonance imaging, were very important in the characterization and diagnosis of this entity.
March 2016: Radiología
https://www.readbyqxmd.com/read/26721302/an-unusual-case-of-noninvasive-adenocarcinoma-arising-in-a-localized-adenomyoma-of-the-gallbladder-and-review-of-literature
#20
Smita Patel, Jamie Slade, Shriram Jakate
Adenomyoma or adenomyomatosis (ADM) of the gallbladder generally carries little or no risk of malignant transformation. Rare cases of such malignant transformation are described in the literature only in segmental type of ADM and not in localized adenomyoma. We report a case of a 58-year-old asymptomatic woman found to have an incidental 3.3 × 3.2 × 2.3 cm well-circumscribed exophytic mass on surveillance ultrasound, originating from the fundus of the gallbladder and abutting the liver capsule. The patient underwent an open cholecystectomy with resection of the mass and underlying segment of the liver...
June 2016: International Journal of Surgical Pathology
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