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https://www.readbyqxmd.com/read/29121416/pregnant-outcomes-of-atypical-polypoid-adenomyoma-treated-with-progestin-therapy
#1
Qin Chen, Weiguo Lu, Bingjian Lu
AIM: We aimed to investigate the long-term clinical and pregnancy outcome in patients with atypical polypoid adenomyoma (APA) after hysteroscopic excision. METHODS: We analyzed the clinicopathological features, including pregnancy outcomes, in 10 APA patients who had been treated with hysteroscopic excision of the lesion and progesterone therapy. RESULTS: The patients were all nulliparous, and nine had been clinically diagnosed as infertile...
November 9, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29098162/sonographic-signs-of-adenomyosis-are-prevalent-in-women-undergoing-surgery-for-endometriosis-and-may-suggest-a-higher-risk-of-infertility
#2
Vered H Eisenberg, Nissim Arbib, Eyal Schiff, Motti Goldenberg, Daniel S Seidman, David Soriano
Objectives: To determine the prevalence of ultrasound features suggestive of adenomyosis in women undergoing surgery for endometriosis compared with a control group of healthy women without endometriosis. Methods: Retrospective case-control study comparing women with intractable pain or infertility, who underwent transvaginal ultrasound and subsequent laparoscopic surgery, with a control group of healthy women without a previous history of endometriosis. A diagnosis of adenomyosis on TVUS was made based on asymmetrical myometrial thickening, linear striations, myometrial cysts, hyperechoic islands, irregular endometrial-myometrial junction, parallel shadowing, and localized adenomyomas and analyzed for one sign and for three or more signs...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29038039/hysteroscopic-transcervical-resection-for-atypical-polypoid-adenomyoma-of-the-uterus-a-valid-fertility-preserving-option
#3
Tatsuyuki Chiyoda, Bao-Liang Lin, Keiko Saotome, Shunki Kiyokawa, Sakura Nakada
STUDY OBJECTIVE: To evaluate hysteroscopic transcervical resection (TCR) for atypical polypoid adenomyoma of the uterus (APA). DESIGN: Retrospective study (Canadian Task Force classification II-2). SETTING: Single tertiary hospital. PATIENTS: Women who underwent TCR for APA at Kawasaki Municipal Hospital between 2003 and 2015. INTERVENTIONS: Clinical records were obtained. MEASUREMENTS AND MAIN RESULTS: Thirty-five APA cases were evaluated...
October 13, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29022861/molecular-characterization-prevalence-and-clinical-relevance-of-phodopus-sungorus-papillomavirus-type-1-psupv1-naturally-infecting-siberian-hamsters-phodopus-sungorus
#4
Boštjan J Kocjan, Lea Hošnjak, Joško Račnik, Marko Zadravec, Nejc Bakovnik, Blaž Cigler, Monique Ummelen, Anton H N Hopman, Nina Gale, Tanja Švara, Mitja Gombač, Mario Poljak
Phodopus sungorus papillomavirus type 1 (PsuPV1), naturally infecting Siberian hamsters (Phodopus sungorus) and clustering in the genus Pipapillomavirus (Pi-PV), is only the second PV type isolated from the subfamily of hamsters. In silico analysis of three independent complete viral genomes obtained from cervical adenocarcinoma, oral squamous cell carcinoma and normal oral mucosa revealed that PsuPV1 encodes characteristic viral proteins (E1, E2, E4, E6, E7, L1 and L2) with conserved functional domains and a highly conserved non-coding region...
November 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28938732/prevalence-of-occult-leiomyosarcomas-and-atypical-leiomyomas-after-laparoscopic-morcellation-of-leiomyomas-in-reproductive-age-women
#5
G Pados, D Tsolakidis, V Theodoulidis, A Makedos, T Zaramboukas, B Tarlatzis
STUDY QUESTION: What is the prevalence of leiomyosarcomas and atypical leiomyomas after laparoscopic morcellation of fibroids in reproductive age women? SUMMARY ANSWER: No case of leiomyosarcomas but seven atypical leiomyomas were found in 1216 subjects. WHAT IS KNOWN ALREADY: Although uterine sarcoma is a rare entity affecting usually older peri- or post-menopausal women, the Food and Drug Administration discourages use of laparoscopic power morcellation of uterine fibroids...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28852646/the-role-of-hysteroscopy-in-the-diagnosis-and-treatment-of-adenomyosis
#6
REVIEW
Attilio Di Spiezio Sardo, Gloria Calagna, Fabrizia Santangelo, Brunella Zizolfi, Vasilis Tanos, Antonino Perino, Rudy Leon De Wilde
Uterine adenomyosis is a common gynecologic disorder in women of reproductive age, characterized by the presence of ectopic endometrial glands and stroma within the myometrium. Dysmenorrhea, abnormal uterine bleeding, chronic pelvic pain, and deep dyspareunia are common symptoms of this pathological condition. However, adenomyosis is often an incidental finding in specimens obtained from hysterectomy or uterine biopsies. The recent evolution of diagnostic imaging techniques, such as transvaginal sonography, hysterosalpingography, and magnetic resonance imaging, has contributed to improving accuracy in the identification of this pathology...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28766580/a-rapidly-enlarging-m%C3%A3-llerian-derived-hepatic-adenomyoma-clinically-mimicking-hepatic-adenoma-in-a-pregnant-woman
#7
Catherine Luedke, Kadiyala Ravindra, Barbara Hertzberg, Carl Berg, Rex Bentley, Xuefeng Zhang
No abstract text is available yet for this article.
August 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28761925/recurrent-atypical-polypoid-adenomyoma-and-pregnancy-a-new-conservative-approach-with-levonorgestrel-releasing-intrauterine-system
#8
Eugenio Solima, Valeria Liprandi, Gaia M Belloni, Michele Vignali, Mauro Busacca
•Levonorgestrel IUD was effective in treatment of recurrent APA.•No side effects were reported.•No impairments on a subsequent pregnancy were reported.
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28739414/conservative-surgery-for-adenomyosis-and-results-a-systematic-review
#9
REVIEW
Grace Younes, Togas Tulandi
The traditional treatment for women with symptomatic adenomyosis is hysterectomy. However, reproductive aged women should be managed with less invasive treatments including medical treatment. For patients who are refractory or unsuitable to long term medical treatment, or those with focal adenomyoma, conservative surgeries could be offered. The objective of our study was to review available conservative surgeries for the treatment of adenomyosis, their complications, and the rates of success and recurrence...
July 21, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28700437/adenomyoma-with-pseudoinvasive-growth-pattern-and-serosal-penetration-mimicking-endometrial-carcinoma
#10
Thomas Raj, Robert DeWitt, Nathaniel E Smith
We present a novel case of a 48-yr-old female with a uterine adenomyoma with an unusual pseudoinvasive growth pattern displaying full-thickness penetration beyond the serosal surface in association with a dehisced Caesarian scar. Before hysterectomy, magnetic resonance imaging findings showed an infiltrative lesion suggestive of endometrial carcinoma. An endometrial biopsy was benign but definitive operative management was pursued given the concerning imaging. Gross examination of the uterus demonstrated a 7...
July 11, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28664484/the-role-of-three-dimensional-power-doppler-hysterosonography-3-dpds-in-distinguishing-atypical-polypoid-adenomyomas-apas-from-other-intrauterine-tumors-correlation-with-pathologic-findings
#11
Kalmantis Konstantinos, Daskalakis Georgios, Semertzidou Anysia, Rodolakis Alexandros
OBJECTIVE: This study was undertaken to describe the sonographic characteristics of atypical polypoid adenomyomas (APAs) of the uterus and to determine the value of three-dimensional power Doppler hysterosonography (3-DPDS) in distinguishing APA from other polypoid uterine tumors. METHODS: Ninety-five women with a mean age of 37 years (range 28-45) with a suspicious polypoid uterine tumor were referred for preoperative evaluation with 3-DPDS. Sonographic criteria used for the diagnosis of APA were based on a system that consisted of morphological characteristics, histological evaluation and power Doppler imaging...
June 29, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28578202/management-of-atypical-polypoid-adenomyomas-a-case-series
#12
Grigoris F Grimbizis, Themistoklis Mikos, Dimosthenis Miliaras, George Kioussis, Theodoros D Theodoridis, Dimitrios Tsolakidis, Basil C Tarlatzis
OBJECTIVE: Atypical polypoid adenomyomas (APAs) are endometrial, non-malignant, focal, and non-invasive lesions that are intriguing for their histological resemblence to invasive endometrioid adenocarcinoma or malignant mixed Müllerian tumor. The aim of this study was to present our clinical experience, regarding the reproductive outcome, the recurrence rate, and the association with hyperplasia and cancer, in a small series of patients with APA. STUDY DESIGN: Retrospective case series of patients treated for APA in a single private hospital setting from 1998 to 2016...
May 22, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28503333/peritoneal-keratin-granulomatosis-associated-with-endometrioid-adenocarcinoma-of-the-uterine-corpus-in-a-woman-with-polycystic-ovaries-a-potential-pitfall-a-case-report-and-review-of-the-literature
#13
Helen J Trihia, Maria Papazian, Natasa Novkovic, John Provatas, Sotiria Tsangouri, Dimitrios C Papatheodorou
Peritoneal keratin granulomatosis is a rare condition included under granulomatous lesions of the peritoneum. It can be secondary to neoplasms of the female genital tract and can mimic carcinomatosis intraoperatively. A case of a 40-year-old woman with a history of polycystic ovaries and a chief complaint of vaginal bleeding is presented. She was diagnosed with endometrioid adenocarcinoma with squamous differentiation in endometrial curettings. Intraoperatively, many peritoneal nodules were found, interpreted as peritoneal carcinomatosis...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28442524/extrauterine-adenomyoma-of-the-liver-in-a-50-year-old-female-with-pelvic-endometriosis
#14
Nidhi Tandon, Josh Showalter, Sadia Sultana, Bihong Zhao, Songlin Zhang
Extrauterine adenomyomas are defined as circumscribed tumor-like masses consisting of smooth muscle tissue, endometrioid glands and stroma. They are extremely rare tumors and similar to their uterine counterparts. We report case of a 50 year old female with an extrauterine adenomyoma of the liver associated with pelvic endometriosis. To the best of our knowledge, only fifteen cases of extrauterine adenomyomas have been reported with only one previous case in the liver. This is the first case of extrauterine adenomyoma of the liver associated with pelvic endometriosis...
March 2017: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/28441840/-atypical-polypoid-adenomyoma-of-the-uterus-a-clinicopathological-review-of-27-cases
#15
T J Bai, D M Bao, Y Li, Y Wang, H Cui, H L Zhu
Objective: To investigate the clinical and pathological characteristics of atypical polypoid adenomyoma (APA) for improvement of the diagnosis, different diagnosis and treatment of the disease. Methods: The clinical data, pathological characteristics, and the follow-up information were retrospectively analyzed in 27 cases of APA admitted in Peking Univeristy People's Hospital from 2007 to 2016. Results: The median age was 42.6 years old (range 25-60 years old). Fifteen patients were nullipara, 2 patients were postmenopausal...
April 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/28416935/juvenile-cystic-adenomyoma-mimicking-a-uterine-anomaly-a-report-of-two-cases
#16
Vatsla Dadhwal, Aparna Sharma, Kavita Khoiwal
Juvenile cystic adenomyoma is a rare form of adenomyosis and described as a new type of mullerian anomaly in literature. We are presenting two cases of juvenile cystic adenomyoma which were misdiagnosed preoperatively as unicornuate uterus with haematometra in a non-communicating rudimentary horn. The mainstay of treatment is complete resection of lesion.
February 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28342392/value-of-the-68-ga-dotatate-pet-ct-in-the-diagnosis-of-endometriosis-a-pilot-study
#17
M Fastrez, C Artigas, N Sirtaine, Z Wimana, M Caillet, S Rozenberg, P Flamen
OBJECTIVE: The non-invasive diagnosis of endometriosis remains challenging. Recent data suggested that somatostatin might be involved in its pathogenesis. High sensitive visualization of somatostatin receptors expression is possible using PET-CT imaging after the administration of a (68)Ga-labeled somatostatin analog (DOTATATE) that will bind to the somatostatin receptor sub-types 2 and 5. The aim of the present study was to assess the usefulness of (68)Ga-DOTATATE PET-CT in the diagnosis of endometriosis...
May 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28288139/mice-deleted-for-cell-division-cycle-73-gene-develop-parathyroid-and-uterine-tumours-model-for-the-hyperparathyroidism-jaw-tumour-syndrome
#18
G V Walls, M Stevenson, K E Lines, P J Newey, A A C Reed, M R Bowl, J Jeyabalan, B Harding, K J Bradley, S Manek, J Chen, P Wang, B O Williams, B T Teh, R V Thakker
The hyperparathyroidism-jaw tumour (HPT-JT) syndrome is an autosomal dominant disorder characterized by occurrence of parathyroid tumours, often atypical adenomas and carcinomas, ossifying jaw fibromas, renal tumours and uterine benign and malignant neoplasms. HPT-JT is caused by mutations of the cell division cycle 73 (CDC73) gene, located on chromosome 1q31.2 and encodes a 531 amino acid protein, parafibromin. To facilitate in vivo studies of Cdc73 in tumourigenesis we generated conventional (Cdc73(+/-)) and conditional parathyroid-specific (Cdc73(+/L)/PTH-Cre and Cdc73(L/L)/PTH-Cre) mouse models...
July 13, 2017: Oncogene
https://www.readbyqxmd.com/read/28248886/endoscopic-submucosal-dissection-for-gastric-adenomyoma-a-rare-entity-of-15-cases-among-571-patients-with-gastric-submucosal-eminence-lesions
#19
Sinan Wang, Hailong Cao, Yujie Zhang, Mengque Xu, Xue Chen, Meiyu Piao, Bangmao Wang
Gastric adenomyoma (GA) is a kind of rare gastric submucosal eminence lesions. As the malignant transformation cannot be ruled out, surgery and laparoscopic resection are usually considered. The aim of this study is to evaluate the therapeutic effect and safety of endoscopic submucosal dissection (ESD) for GA.All of the patients with gastric submucosal eminence lesions who underwent ESD from June 2008 to June 2015 in General Hospital, Tianjin Medical University, China, were identified, and patients with GA, which was confirmed by pathological evaluation, were enrolled for further analysis...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28197875/mri-us-or-real-time-virtual-sonography-in-the-evaluation-of-adenomyosis
#20
COMPARATIVE STUDY
Valeria Vinci, Matteo Saldari, Maria Eleonora Sergi, Silvia Bernardo, Giuseppe Rizzo, Maria Grazia Porpora, Carlo Catalano, Lucia Manganaro
PURPOSE: Real-time virtual sonography (RVS) allows displaying and synchronizing real-time US and multiplanar reconstruction of MRI images. The purpose of this study was to evaluate the feasibility and ability of RVS to assess adenomyosis since literature shows US itself has a reduced diagnostic accuracy compared to MRI. MATERIALS AND METHODS: This study was conducted over a 4-month period (March-June 2015). We enrolled in the study 52 women with clinical symptoms of dysmenorrhea, methrorragia and infertility...
May 2017: La Radiologia Medica
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