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"Patient Blood Management"

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https://www.readbyqxmd.com/read/29770734/post-transfusion-hemoglobin-values-and-patient-blood-management
#1
Jan Moerman, Edith Vermeulen, Mia Van Mullem, Anne-Mie Badts, Peter Lybeert, Veerle Compernolle, Jørgen Georgsen
Objectives The objective of this retrospective study was to evaluate the added value of communicating post-transfusion hemoglobin values to clinicians as a strategy to improve RBC utilization in a 500-bed hospital. Methods The total number of RBC transfusions, the mean number of RBC units transfused per patient, the mean pre- and post-transfusion hemoglobin values, the ratio of patients transfused and the ratio of patients with a post-transfusion hemoglobin > 10.5 g/dL were calculated per service and per department for six months...
May 17, 2018: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29756664/patient-blood-management-how-is-implementation-going-a-report-comparing-the-2015-survey-with-the-2013-survey-of-pbm-in-england
#2
L Sherliker, K Pendry, B Hockley
BACKGROUND: Patient blood management (PBM) is an evidence-based approach to optimising the care of patients who might need transfusion. In 2013, all NHS Trusts in England were surveyed about their readiness to implement PBM. National PBM recommendations were launched in 2014. AIMS: The aim of this study was to determine progress of PBM initiatives. METHODS/MATERIALS: A survey was constructed by staff in hospitals and NHS Blood and Transplant (NHSBT)...
April 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/29744976/what-in-the-world-of-transfusion-medicine-isn-t-patient-blood-management
#3
EDITORIAL
M H Yazer, J H Waters
No abstract text is available yet for this article.
April 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/29744975/patient-blood-management-a-renaissance-of-transfusion-medicine
#4
EDITORIAL
L J Estcourt, D J Roberts
No abstract text is available yet for this article.
April 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/29714029/a-data-driven-patient-blood-management-strategy-in-liver-transplantation
#5
R A Metcalf, M B Pagano, J R Hess, J Reyes, J D Perkins, M I Montenovo
BACKGROUND AND OBJECTIVES: Blood utilization during liver transplant has decreased, but remains highly variable due to many complex surgical and physiologic factors. Previous models attempted to predict utilization using preoperative variables to stratify cases into two usage groups, usually using entire blood units for measurement. We sought to develop a practical predictive model using specific transfusion volumes (in ml) to develop a data-driven patient blood management strategy. MATERIALS AND METHODS: This is a retrospective evaluation of primary liver transplants at a single institution from 2013 to 2015...
May 1, 2018: Vox Sanguinis
https://www.readbyqxmd.com/read/29676943/impact-of-preoperative-thrombocytopenia-on-the-outcome-after-coronary-artery-bypass-grafting
#6
Wail Nammas, Magnus Dalén, Stefano Rosato, Riccardo Gherli, Daniel Reichart, Giuseppe Gatti, Francesco Onorati, Giuseppe Faggian, Marisa De Feo, Ciro Bancone, Sidney Chocron, Sorosh Khodabandeh, Giuseppe Santarpino, Antonino S Rubino, Daniele Maselli, Saverio Nardella, Antonio Salsano, Tiziano Gherli, Francesco Nicolini, Marco Zanobini, Matteo Saccocci, Karl Bounader, Paola D'Errigo, Tuomas Kiviniemi, Eeva-Maija Kinnunen, Andrea Perrotti, Juhani Airaksinen, Giovanni Mariscalco, Vito G Ruggieri, Fausto Biancari
The impact of thrombocytopenia on postoperative bleeding and other major adverse events after cardiac surgery is unclear. This issue was investigated in a series of patients who underwent isolated coronary artery bypass grafting (CABG) from the prospective, multicenter E-CABG registry. Preoperative thrombocytopenia was defined as preoperative platelet count <150 × 109 /L and it was considered moderate-severe when preoperative platelet count was <100 × 109 /L. Multilevel mixed-effects regression analysis was performed to adjust the effect of thrombocytopenia on outcomes for baseline and operative covariates as well as for interinstitutional differences in patient-blood management...
April 20, 2018: Platelets
https://www.readbyqxmd.com/read/29667253/patient-blood-management-what-does-this-actually-mean-for-neonates-and-infants
#7
REVIEW
G L Crighton, H V New, H G Liley, S J Stanworth
Patient blood management (PBM) refers to an evidence-based package of care that aims to improve patient outcomes by optimal use of transfusion therapy, including managing anaemia, preventing blood loss and improving anaemia tolerance in surgical and other patients who may need transfusion. In adults, PBM programmes are well established, yet the definition and implementation of PBM in neonates and children lags behind. Neonates and infants are frequently transfused, yet they are often under-represented in transfusion trials...
April 17, 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/29660827/patient-blood-management-and-the-importance-of-the-transfusion-practitioner-role-to-embed-this-into-practice
#8
REVIEW
L Bielby, R L Moss
Patient blood management (PBM) is a widely established international initiative, with a multidisciplinary approach to reduce transfusion. The Transfusion Practitioner (TP) role is well embedded in the United Kingdom (UK) and Australia. The value of the TP in changing both culture and practice to implement an all-inclusive PBM approach to care will be discussed. The TP role was born from both a safety and haemovigilance culture, where the greatest identified risk to the patient undergoing a transfusion was human error...
April 16, 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/29582437/red-blood-cell-transfusion-after-a-global-strategy-for-early-detection-and-treatment-of-iron-deficiency-anemia-three-year-results-of-a-prospective-observational-study
#9
Miguel Angel de Las Nieves Lopez, Ana Maria Matas Cobos, Francisco Sarria Gonzalez, Maria Jose Dominguez Lomeña, Ana Maria Palomo Hernandez, Encarnación Gil Gines, Salvador Serna Juan, Javier Ampuero Ampuero, Antonio Marin Fernandez, Antonia Vazquez de la Villa
BACKGROUND: Anemia is the main indication for red blood cell (RBC) transfusion and iron deficiency is the most prevalent, preventable, and treatable cause of anemia worldwide. We aimed to assess the impact of iron deficiency anemia (IDA) on RBC transfusion by means of a program for prevention, early detection, and treatment. STUDY DESIGN AND METHODS: A prospective observational study was conducted starting in 2014 after an intervention in clinical practice in Melilla, a peripheral city isolated by 207 km sea distance to nearest continental Spain...
March 26, 2018: Transfusion
https://www.readbyqxmd.com/read/29577348/preoperative-autologous-blood-collection-before-bone-marrow-harvests-in-haploidentical-related-donors-is-it-justified
#10
Komal Arora, James Kelley, Fernando Martinez, Ashok Tholpady
BACKGROUND: With the increasing safety of allogeneic blood supply and declining need for transfusion due to patient blood management, the practice of preoperative autologous donation (PAD) continues to decline. The practice gained popularity during the 1980s and 1990s with the emergence of transfusion-transmitted human immunodeficiency virus and hepatitis C. At the peak of this public concern, the National Marrow Donor Program recommended that marrow donors have 1 to 3 autologous units of blood collected before their marrow harvest to minimize the likelihood of allogeneic transfusion...
March 25, 2018: Transfusion
https://www.readbyqxmd.com/read/29542136/five-year-trends-in-perioperative-red-blood-cell-transfusion-from-index-cases-in-five-surgical-specialties-2011-to-2015
#11
Michael A Mazzeffi, John M See, Brittney Williams, Justin Richards, Darin Zimmerman, Samuel Galvagno, Magali Fontaine, Kenichi Tanaka
BACKGROUND: Red blood cell (RBC) transfusion can be life-saving; however, the risks of RBC transfusion have been increasingly recognized, and current guidelines recommend restrictive transfusion in most patients. We hypothesized that RBC transfusions are decreasing in surgical patients. STUDY DESIGN AND METHODS: A retrospective review of the National Surgical Quality Improvement Program database was performed from 2011 to 2015. Index cases in five surgical specialties were studied: neurosurgery, thoracic surgery, gynecologic surgery, orthopedic surgery, and vascular surgery...
May 2018: Transfusion
https://www.readbyqxmd.com/read/29525470/management-of-peri-operative-anaemia-in-a-patient-with-rare-alloantibodies-scheduled-for-oesophagectomy
#12
E García, M P Blanco, S Riaño, I González-Mendibil, T Carrascosa, M T Antolín
A description is presented on the management of a patient with an oesophageal neoplasm scheduled for oesophagectomy. Alloantibodies were detected during a blood components reservation procedure, which made it almost impossible to obtain compatible blood. Peri-operative anaemia management or "Patient Blood Management" should be routinely performed in all patients at transfusion risk. This strategy has been considered as one of the actions to bear in mind in fast-track surgery or enhanced recovery after surgery...
March 7, 2018: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/29517965/a-model-based-cost-effectiveness-analysis-of-patient-blood-management
#13
Adina Kleinerüschkamp, Patrick Meybohm, Niels Straub, Kai Zacharowski, Suma Choorapoikayil
BACKGROUND: Patient blood management (PBM) is a multidisciplinary concept focused on the management of anaemia, minimisation of iatrogenic blood loss and rational use of allogeneic blood products. The aims of this study were: (i) to analyse post-operative outcome in patients with liberal vs restrictive exposure to allogeneic blood products and (ii) to evaluate the cost-effectiveness of PBM in patients undergoing surgery. MATERIALS AND METHODS: A systematic literature review and meta-analysis were performed to compare post-operative complications in predominantly non-transfused patients (restrictive transfusion group) and patients who received one to three units of red blood cells (liberal transfusion group)...
February 16, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29508467/towards-a-systematic-approach-for-de-implementation-of-patient-blood-management-strategies
#14
REVIEW
V M A Voorn, L van Bodegom-Vos, C So-Osman
Despite the increasing availability of evidence in transfusion medicine literature, this evidence does not automatically find its way into practice. This is also applicable to patient blood management (PBM). It may concern the lack of implementation of effective new techniques or treatments, or it may apply to the (over)use of techniques and treatments (e.g. inappropriate transfusions) that have proven to be of limited benefit for patients (low-value care) and could be abandoned (de-implementation). In PBM literature, the implementation of restrictive transfusion thresholds and the de-implementation of inappropriate transfusions are described...
April 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/29459001/three-point-transfusion-risk-score-in-hepatectomy-an-external-validation-using-the-american-college-of-surgeons-national-surgical-quality-improvement-program-acs-nsqip
#15
Madeline Lemke, Alyson Mahar, Paul J Karanicolas, Natalie G Coburn, Calvin H L Law, Julie Hallet
BACKGROUND: Risk of red blood cell transfusion (RBCT) in partial hepatectomy is 17-27%; strategies to reduce transfusions can be targeted in patients at increased risk. A Three Point Transfusion Risk Score (TRS) was previously developed to predict patients' risk of transfusion during and following hepatectomy. Here, it was subject to external validation using the ACS-NSQIP database. METHODS: TRIPOD guidelines were followed. A validation cohort was created with the ACS-NSQIP dataset...
February 16, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29425595/diffusing-innovation-and-best-practice-in-health-care
#16
REVIEW
Philip E Greilich, Mary Eleanor Phelps, William Daniel
Diffusing innovation and best practices in healthcare are among the most challenging aspects of advancing patient safety and quality improvement. Recommendations from the Baldrige Foundation, Institute for Healthcare Improvement, and The Joint Commission provide guidance on the principles for successful diffusion. Perioperative leaders are encouraged to applying these principles to high priority areas such as handovers, enhanced recovery and patient blood management. Completing a successful pilot project can be exciting, however, effective diffusion is essential to achieving meaningful and lasting impact on the service line and health system...
March 2018: Anesthesiology Clinics
https://www.readbyqxmd.com/read/29408837/reply-the-important-role-for-intravenous-iron-in-perioperative-patient-blood-management-in-major-abdominal-surgery-a-randomized-controlled-trial
#17
Bernd Froessler, Peter Palm, Ingo Weber, Nicolette A Hodyl, Rajvinder Singh, Elizabeth M Murphy
No abstract text is available yet for this article.
March 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29398320/the-prognostic-role-of-perioperative-allogeneic-blood-transfusions-in-gastric-cancer-patients-undergoing-curative-resection-a-systematic-review-and-meta-analysis-of-non-randomized-adjusted-studies
#18
REVIEW
Annamaria Agnes, Maria Carmen Lirosi, Simona Panunzi, Pietro Santocchi, Roberto Persiani, Domenico D'Ugo
The impact of allogeneic perioperative blood transfusions (APTs) on the prognosis of gastric cancer patients undergoing curative-intent gastrectomy is still a highly debated topic. Two meta-analyses were published in 2015, and new studies report conflicting results. A literature review was conducted using PubMed, Scopus, the Cochrane Central Register of Controlled Trials and the Cochrane Database of Systematic Reviews, updated to March 1, 2016. Thirty-eight non-randomized studies reporting data on overall survival (OS), disease-free survival (DFS), disease-specific survival (DSS) and postoperative complications (PCs) were included...
April 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29373189/patient-blood-management-in-cardiac-surgery-results
#19
A Pajares, L Larrea, I Zarragoikoetexea, A Tur, R Vicente, P Argente
OBJECTIVE: The main objective of the study was to evaluate the effect of implementing a blood-saving programme in patients undergoing elective cardiac surgery with an analysis of the transfusion rate and complications. MATERIALS AND METHODS: A single-centre, observational, retrospective, comparative study which included 604 consecutive patients older than 15 years old undergoing elective cardiac surgery. Two groups of patients were created according to whether or not they were included in a blood-saving protocol, and analysed between December 2012 and July 2013 (293 patients, prep group) and April 2015 to May 2016 (311 patients, posp group)...
April 2018: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/29368267/-prophylactic-use-of-tranexamic-acid-in-noncardiac-surgery-update-2017
#20
REVIEW
J Waskowski, J C Schefold, F Stueber
BACKGROUND: Minimising perioperative bleeding is a key goal of "patient blood management" programs. One component of respective strategies includes preventive inhibition of fibrinolysis using protease inhibitors, such as tranexamic acid (TXA). TXA inhibits plasminogen activation and plasmin-induced fibrin degradation. OBJECTIVES: The present article provides an overview of the existing literature and TXA applications in the prophylaxis of perioperative bleeding...
January 24, 2018: Medizinische Klinik, Intensivmedizin und Notfallmedizin
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