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https://www.readbyqxmd.com/read/28088409/genome-wide-association-analysis-and-pathways-enrichment-for-lactation-persistency-in-canadian-holstein-cattle
#1
D N Do, N Bissonnette, P Lacasse, F Miglior, M Sargolzaei, X Zhao, E M Ibeagha-Awemu
Lactation persistency (LP), defined as the rate of declining milk yield after milk peak, is an economically important trait for dairy cattle. Improving LP is considered a good alternative method for increasing overall milk production because it does not cause the negative energy balance and other health issues that cows experience during peak milk production. However, little is known about the biology of LP. A genome-wide association study (GWAS) and pathway enrichment were used to explore the genetic mechanisms underlying LP...
January 11, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28088407/far-off-and-close-up-dry-matter-intake-modulate-indicators-of-immunometabolic-adaptations-to-lactation-in-subcutaneous-adipose-tissue-of-pasture-based-transition-dairy-cows
#2
M Vailati-Riboni, G Farina, F Batistel, A Heiser, M D Mitchell, M A Crookenden, C G Walker, J K Kay, S Meier, J R Roche, J J Loor
The common practice of increasing dietary energy density during the close-up dry period (last ∼3 wk prepartum) has been recently associated with a higher incidence of metabolic disorders after calving. Despite these reports, over-feeding of metabolizable energy (ME) during the far-off, nonlactating period is a common management policy aimed at achieving optimum calving body condition score (BCS) in pasture-based systems, as cows are generally thinner than total mixed ration cows at the end of lactation. Our hypothesis was that both far-off and close-up overfeeding influence the peripartum adipose tissue changes associated with energy balance and inflammatory state...
January 11, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28087269/mitochondrial-roles-of-the-psychiatric-disease-risk-factor-disc1
#3
REVIEW
R Norkett, S Modi, J T Kittler
Ion transport during neuronal signalling utilizes the majority of the brain's energy supply. Mitochondria are key sites for energy provision through ATP synthesis and play other important roles including calcium buffering. Thus, tightly regulated distribution and function of these organelles throughout the intricate architecture of the neuron is essential for normal synaptic communication. Therefore, delineating mechanisms coordinating mitochondrial transport and function is essential for understanding nervous system physiology and pathology...
January 10, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28081150/the-association-of-birth-weight-and-infant-growth-with-energy-balance-related-behavior-a-systematic-review-and-best-evidence-synthesis-of-human-studies
#4
Arend W van Deutekom, Mai J M Chinapaw, Elise P Jansma, Tanja G M Vrijkotte, Reinoud J B J Gemke
BACKGROUND: Suboptimal prenatal and early postnatal growths are associated with obesity in later life, but the underlying mechanisms are unknown. The aim of this study was to systematically review the literature that reports on the longitudinal association of (i) birth size or (ii) infant growth with later (i) energy intake, (ii) eating behaviors, (iii) physical activity or (iv) sedentary behavior in humans. METHODS: A comprehensive search of MEDLINE, EMBASE, PsycINFO and The Cochrane Library was conducted to identify relevant publications...
2017: PloS One
https://www.readbyqxmd.com/read/28080834/low-adherence-to-dietary-guidelines-in-spain-especially-in-the-overweight-obese-population-the-anibes-study
#5
Elena Rodríguez-Rodríguez, Aránzazu Aparicio, Javier Aranceta-Bartrina, Ángel Gil, Marcela González-Gross, Lluis Serra-Majem, Gregorio Varela-Moreiras, Rosa M Ortega
OBJECTIVE: The objective of this study was to analyze the dietary intake of the Spanish population according to ponderal status and body fat distribution. METHODS: Data were obtained from ANIBES (Anthropometry, Intake, and Energy Balance in Spain), a cross-sectional study of a nationally representative sample (1013 men, 996 women) of the Spanish population (18-64 years). The final fieldwork was carried out from mid-September to November (three months) 2013. A 3-day dietary record provided information about food and beverage consumption...
January 12, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28077863/what-have-human-experimental-overfeeding-studies-taught-us-about-adipose-tissue-expansion-and-susceptibility-to-obesity-and-metabolic-complications
#6
REVIEW
D J Cuthbertson, T Steele, J P Wilding, J C G Halford, J A Harrold, M Hamer, F Karpe
Overfeeding experiments, in which we impose short-term positive energy balance, help unravel the cellular, physiological and behavioural adaptations to nutrient excess. These studies mimic longer-term mismatched energy expenditure and intake. There is considerable inter-individual heterogeneity in the magnitude of weight gain when exposed to similar relative caloric excess reflecting variable activation of compensatory adaptive mechanisms. Significantly, given similar relative weight gain, individuals may be protected from/predisposed to metabolic complications (insulin resistance, dyslipidaemia, hypertension), non-alcoholic fatty liver disease and cardiovascular disease...
January 12, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28077715/excitatory-hindbrain-forebrain-communication-is-required-for-cisplatin-induced-anorexia-and-weight-loss
#7
Amber L Alhadeff, Ruby A Holland, Huiyuan Zheng, Linda Rinaman, Harvey J Grill, Bart C De Jonghe
: Cisplatin chemotherapy is commonly used to treat cancer despite severe energy balance side effects. In rats, cisplatin activates nucleus tractus solitarius (NTS) projections to the lateral parabrachial nucleus (lPBN) and calcitonin-gene related peptide (CGRP) projections from the lPBN to the central nucleus of the amygdala (CeA). We demonstrated previously that CeA glutamate receptor signaling mediates cisplatin-induced anorexia and body weight loss. Here, we used neuroanatomical tracing, immunofluorescence, and confocal imaging to demonstrate that virtually all NTS→lPBN and lPBN→CeA CGRP projections coexpress vesicular glutamate transporter 2 (VGLUT2), providing evidence that excitatory projections mediate cisplatin-induced energy balance dysregulation...
January 11, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28076653/recent-advances-in-primate-nutritional-ecology
#8
Nicoletta Righini
Nutritional ecology seeks to explain, in an ecological and evolutionary context, how individuals choose, acquire, and process food to satisfy their nutritional requirements. Historically, studies of primate feeding ecology have focused on characterizing diets in terms of the botanical composition of the plants consumed. Further, dietary studies have demonstrated how patch and food choice in relation to time spent foraging and feeding are influenced by the spatial and temporal distribution of resources and by social factors such as feeding competition, dominance, or partner preferences...
January 11, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28075372/distributed-sensor-nodes-charged-by-mobile-charger-with-directional-antenna-and-by-energy-trading-for-balancing
#9
Celso Moraes, Sunghee Myung, Sangkeum Lee, Dongsoo Har
Provision of energy to wireless sensor networks is crucial for their sustainable operation. Sensor nodes are typically equipped with batteries as their operating energy sources. However, when the sensor nodes are sited in almost inaccessible locations, replacing their batteries incurs high maintenance cost. Under such conditions, wireless charging of sensor nodes by a mobile charger with an antenna can be an efficient solution. When charging distributed sensor nodes, a directional antenna, rather than an omnidirectional antenna, is more energy-efficient because of smaller proportion of off-target radiation...
January 10, 2017: Sensors
https://www.readbyqxmd.com/read/28074900/physical-controllability-of-complex-networks
#10
Le-Zhi Wang, Yu-Zhong Chen, Wen-Xu Wang, Ying-Cheng Lai
A challenging problem in network science is to control complex networks. In existing frameworks of structural or exact controllability, the ability to steer a complex network toward any desired state is measured by the minimum number of required driver nodes. However, if we implement actual control by imposing input signals on the minimum set of driver nodes, an unexpected phenomenon arises: due to computational or experimental error there is a great probability that convergence to the final state cannot be achieved...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28074888/a-review-of-the-carbohydrate-insulin-model-of-obesity
#11
REVIEW
K D Hall
The carbohydrate-insulin model of obesity theorizes that diets high in carbohydrate are particularly fattening due to their propensity to elevate insulin secretion. Insulin directs the partitioning of energy toward storage as fat in adipose tissue and away from oxidation by metabolically active tissues and purportedly results in a perceived state of cellular internal starvation. In response, hunger and appetite increases and metabolism is suppressed, thereby promoting the positive energy balance associated with the development of obesity...
January 11, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28074773/low-dose-dialysis-combined-with-low-protein-intake-can-maintain-nitrogen-balance-in-peritoneal-dialysis-patients-in-poor-economies%C3%A2
#12
Chun-Yan Su, Tao Wang, Xin-Hong Lu, Sha Ma, Wen Tang, Pei-Yu Wang
OBJECTIVE: Due to limited economic conditions, we tried to provide "fitted" dialysis doses instead of the doses recommended by the international guidelines to the individual patients. In the present cross-sectional study, we studied the dialysis adequacy and nutritional status of 5 peritoneal dialysis patients who had a low dialysis dose (2 bags, 4,000 mL/day). METHODS: The 3-day dietary records were reviewed to calculate patients' energy, protein, and nitrogen intake (NI)...
January 11, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28074612/a-new-cuo-fe2o3-mcmb-conversion-anode-in-high-performance-lithium-ion-battery-using-li1-35ni0-48fe0-1mn1-72o4-spinel-cathode
#13
Daniele Di Lecce, Roberta Verrelli, Daniele Campanella, Vittorio Marangon, Jusef Hassoun
Ternary CuO-Fe2O3-MCMB conversion anode is herein characterized and combined with high-voltage Li1.35Ni0.48Fe0.1Mn1.72O4 spinel cathode in a lithium-ion battery of relevant performances in terms of cycling stability and rate capability. The CuO-Fe2O3-MCMB composite is prepared using high-energy milling, i.e., a low-cost pathway which leads to a crystalline structure, and homogeneous submicrometrical morphology revealed by X-ray diffraction and electronic microscopy. The anode reversibly exchanges lithium ions by conversion reactions of CuO and Fe2O3, as well as by insertion into MCMB carbon...
January 10, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28071834/molecular-profiling-of-human-ips-derived-hypothalamic-neurons-provides-developmental-insights-to-genetic-loci-for-body-weight-regulation
#14
Li Yao, Yuanhang Liu, Zhifang Qiu, Satish Kumar, Joanne E Curran, John Blangero, Yidong Chen, Donna M Lehman
BACKGROUND/OBJECTIVES: Recent data suggests that common genetic risk for metabolic disorders such as obesity may be human-specific and exert effects through the central nervous system. To overcome the limitation of human tissue access for study, we have generated induced human pluripotent stem cell (hiPSC)-derived neuronal cultures which recapture many features of hypothalamic neurons within the arcuate nucleus. Here we have comprehensively characterized this model across development, benchmarked these neurons to in vivo events, and demonstrate a link between obesity risk variants and hypothalamic development...
January 10, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/28070976/efficient-deep-blue-electroluminescence-based-on-phenanthroimidazole-dibenzothiophene-derivatives-with-different-oxidation-states-of-sulfur-atom
#15
Xiangyang Tang, Tong Shan, Qing Bai, Hongwei Ma, Xin He, Ping Lu
Developing efficient deep blue materials is a long term research focus in the field of organic light emitting diodes (OLEDs). In this paper, we report two deep blue molecules, PITO and PISF, which share similar chemical structures but exhibit different photophysical and device properties. These two molecules consist of phenanthroimidazole and dibenzothiophene analogues. The distinction of their chemical structures lies in the different oxidation states of the S atom. For PITO, the S atom is oxidized and the resulting structure dibenzothiophene S,S-dioxide becomes electron deficient...
January 10, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28070813/cr-vi-reduction-and-cr-iii-immobilization-by-resting-cells-of-pseudomonas-aeruginosa-cctcc-ab93066-spectroscopic-microscopic-and-mass-balance-analysis
#16
Chunxi Kang, Pingxiao Wu, Liping Li, Langfeng Yu, Bo Ruan, Beini Gong, Nengwu Zhu
The aim of this study was to investigate the mechanism of Cr(VI) reduction and Cr(III) immobilization by resting cells of Pseudomonas aeruginosa using batch experiments and analysis techniques. Data showed that resting cells of this strain (3.2 g/L dry weight) reduced 10 mg/L of Cr(VI) by 86% in Tris-HCl buffer solution under optimized conditions of 5 g/L of sodium acetate as an electron donor, pH of 7.0 and temperature of 37 °C within 24 h. Cr(VI) was largely converted to nontoxic Cr(III), and both soluble crude cell-free extracts and membrane-associated fractions were responsible for Cr(VI) reduction...
January 9, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28070278/entanglement-is-a-costly-life-history-stage-in-large-whales
#17
Julie van der Hoop, Peter Corkeron, Michael Moore
Individuals store energy to balance deficits in natural cycles; however, unnatural events can also lead to unbalanced energy budgets. Entanglement in fishing gear is one example of an unnatural but relatively common circumstance that imposes energetic demands of a similar order of magnitude and duration of life-history events such as migration and pregnancy in large whales. We present two complementary bioenergetic approaches to estimate the energy associated with entanglement in North Atlantic right whales, and compare these estimates to the natural energetic life history of individual whales...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28069223/sustained-release-formulations-of-citronella-oil-nanoemulsion-using-cavitational-techniques
#18
Naveen Agrawal, Ganesh L Maddikeri, Aniruddha B Pandit
Nanoemulsion synthesis has proven to be an effective way for transportation of immobile, insoluble bioactive compounds. Citronella Oil (lemongrass oil), a natural plant extract, can be used as a mosquito repellent and has less harmful effects compared to its available market counterpart DEET (N, N-Diethyl-meta-toluamide). Nanoemulsion of citronella oil in water was prepared using cavitation-assisted techniques while investigating the effect of system parameters like HLB (Hydrophilic Lipophilic Balance), surfactant concentration, input energy density and mode of power input on emulsion quality...
May 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28067242/submesoscale-transition-from-geostrophic-flows-to-internal-waves-in-the-northwestern-pacific-upper-ocean
#19
Bo Qiu, Toshiya Nakano, Shuiming Chen, Patrice Klein
With radar interferometry, the next-generation Surface Water and Ocean Topography satellite mission will improve the measured sea surface height resolution down to 15 km, allowing us to investigate for the first time the global upper ocean variability at the submesoscale range. Here, by analysing shipboard Acoustic Doppler Current Profiler measurements along 137°E in the northwest Pacific of 2004-2016, we show that the observed upper ocean velocities are comprised of balanced geostrophic flows and unbalanced internal waves...
January 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28066917/balancing-exploration-and-exploitation-in-population-based-sampling-improves-fragment-based-de-novo-protein-structure-prediction
#20
David Simoncini, Thomas Schiex, Kam Y J Zhang
Conformational search space exploration remains a major bottleneck for protein structure prediction methods. Population-based meta-heuristics typically enable the possibility to control the search dynamics and to tune the balance between local energy minimization and search space exploration. EdaFold is a fragment-based approach that can guide search by periodically updating the probability distribution over the fragment libraries used during model assembly. We implement the EdaFold algorithm as a Rosetta protocol and provide two different probability update policies: a cluster-based variation (EdaRosec ) and an energy-based one (EdaRoseen ) We analyze the search dynamics of our new Rosetta protocols and show that EdaRosec EdaRosec is able to provide predictions with lower Cα RMSD to the native structure than EdaRoseen and Rosetta AbInitio Relax protocol...
January 9, 2017: Proteins
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