keyword
MENU ▼
Read by QxMD icon Read
search

Extranodal extension

keyword
https://www.readbyqxmd.com/read/29768336/primary-diffuse-large-b-cell-lymphoma-in-the-maxilla-a-case-report
#1
Haixiao Zou, Haili Yang, Yuan Zou, Lang Lei, Li Song
RATIONALE: Lymphomas are the second most common non-epithelial malignant tumors in the oral and maxillofacial region. Non-Hodgkin's lymphoma (NHL) develops at extranodal sites, and cases involving the maxilla account for less than 1% of all NHLs. We describe a case of diffuse large B-cell lymphoma (DLBCL) in the maxilla, and highlight the clinical signs, symptoms, differential diagnosis, and appropriate treatment of DLBCL in the oral cavity and maxillofacial region. PATIENT CONCERNS: A 67-year-old woman was admitted to our surgical department with pain and swelling in her right upper posterior teeth for about six months...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29742277/development-of-a-novel-salivary-gland-cancer-lymph-node-staging-system
#2
Katri Aro, Allen S Ho, Michael Luu, Sungjin Kim, Mourad Tighiouart, Jon Mallen-St Clair, Emi J Yoshida, Stephen L Shiao, Ilmo Leivo, Zachary S Zumsteg
BACKGROUND: Current lymph node (LN) staging for salivary gland cancer (SGC) is extrapolated from mucosal head and neck squamous cell carcinoma. However, given its unique biology and clinical behavior, it is possible that a SGC-specific LN staging system would be more accurate. METHODS: Patients from the National Cancer Data Base with nonmetastatic SGC of the head and neck who were diagnosed from 2004 through 2013 and underwent surgical resection and neck dissection removing at least 10 LNs were included...
May 9, 2018: Cancer
https://www.readbyqxmd.com/read/29730912/-clinicopathological-and-ultrasound-characteristics-of-extranodal-extension-in-metastatic-papillary-thyroid-carcinoma-patients
#3
J L Mu, F X Li, X Wei, X J Xin, S Zhang
Objective: To explore clinicopathological and ultrasound characteristics of extranodal extension in metastatic papillary thyroid carcinoma patients. Methods: 176 patients with papillary thyroid carcinoma who were diagnosed in Tianjin Medical University Cancer Institute and Hospital between March 2011 and March 2016 were identified and recruited in the study. Among the 176 patients, 59 patients were diagnosed with regional lymph nodes metastasis accompanied with extranodal extension (extranodal extension positive group), 117 patients were regional lymph nodes metastasis without extranodal extension (extranodal extension negative group)...
April 23, 2018: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29720012/extranodal-rosai-dorfman-disease-with-mucosal-involvement-of-the-stomach-in-a-background-of-autoimmune-atrophic-gastritis
#4
Amanda Meindl, M Sambasiva Rao, Guang-Yu Yang
Rosai-Dorfman disease (RDD), or sinus histiocytosis with massive lymphadenopathy, has been described involving both lymph nodes and extranodal sites, but extranodal RDD rarely involves the gastrointestinal tract. Although the etiology is unclear, several risk factors have been shown to be highly associated with this disease process, including viral infection and immune alterations. In this article, we present a case of a 79-year-old male with a history of autoimmune atrophic gastritis and multiple carcinoid tumors of the stomach presenting with a new stomach mass...
May 1, 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29703686/risks-and-benefits-of-adjuvant-radiotherapy-after-inguinal-lymphadenectomy-in-node-positive-penile-cancer-a-systematic-review-by-the-european-association-of-urology-penile-cancer-guidelines-panel
#5
REVIEW
Richard Robinson, Lorenzo Marconi, Ekelechi MacPepple, Oliver W Hakenberg, Nick Watkin, Yuhong Yuan, Thomas Lam, Steven MacLennan, Temitope E Adewuyi, Alberto Coscione, Suks S Minhas, Eva M Compérat, Andrea Necchi
CONTEXT: Management of men with penile squamous cell carcinoma (PSCC) who have high-risk features following radical inguinal lymphadenectomy (ILND) remains controversial. European Association of Urology guidelines state that adjuvant inguinal radiotherapy (AIRT) is "not generally recommended". Despite this, many centres continue to offer AIRT to a subset of men. OBJECTIVE: To undertake a systematic review of the evidence on AIRT in node-positive men with PSCC...
April 24, 2018: European Urology
https://www.readbyqxmd.com/read/29658104/comparison-of-the-seventh-and-eighth-edition-american-joint-committee-on-cancer-oral-cavity-staging-systems
#6
John D Cramer, Abhita Reddy, Robert L Ferris, Umamaheswar Duvvuri, Sandeep Samant
OBJECTIVE: For the first time in 30 years, the eighth edition of the American Joint Committee on Cancer (AJCC) Staging Manual offers major changes in the staging of oral cavity cancer. We evaluated the predictive ability of the new staging system for oral cavity cancer to validate these changes and hypothesized that the new system would improve prognostic accuracy. METHODS: We conducted a retrospective cohort study of patients with oral cavity squamous cell carcinoma in the National Cancer Data Base from 2009 to 2013 and applied the seventh and eighth edition staging AJCC staging systems to all patients...
April 15, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29617785/extended-bronchoplasty-for-locally-advanced-left-lower-lobe-lung-cancer-surgical-technique-and-outcomes
#7
Tomoyuki Hishida, Keiju Aokage, Junji Yoshida, Tomohiro Miyoshi, Masahiro Tsuboi
Extended bronchoplasty combined with left lower lobectomy plus lingulectomy can be indicated for some locally advanced left lower lobe cancers to avoid pneumonectomy, but its outcome has not been well studied. We retrospectively analysed the surgical outcomes of 10 patients since 2008, when we introduced this procedure. The median age was 67 years (range 42-80). Squamous cell carcinoma was the most common histology. The indication for this procedure was bulky or extranodal metastasis in an interlobar node in 9 patients and massive tumour invasion to the lingula in 1 patient...
April 2, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29608251/cervical-lymph-node-carcinoma-metastasis-from-unknown-primary-site-a-retrospective-analysis-of-154-patients
#8
Yan Wang, Sha-Sha He, Yong Bao, Xiu-Yu Cai, Hai-Yang Chen, Xing-Li Yang, Dan-Ming Chen, Li-Xia Lu, Yong Chen
Despite advances in diagnosis and treatment, the existence of cervical lymph node carcinoma of unknown primary site (CCUP) has always been an urgent problem worldwide. There is still no consensus on the optimal management for CCUP. In this retrospective review, we analyze the clinical characteristics of CCUP patients treated at our institution and examine how these characteristics and treatments were associated with survival. Clinicopathologic features, treatments, and survival outcomes of 154 CCUP patients were collected from the hospital records and analyzed...
April 2, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29544756/cervical-lymph-node-metastatic-status-and-adjuvant-therapy-predict-the-prognosis-of-salivary-duct-carcinoma
#9
Kai Qian, Lu Di, Kai Guo, Xiaoke Zheng, Qinghai Ji, Zhuoying Wang
PURPOSE: Salivary duct carcinoma (SDC) is an aggressive malignancy that is not yet fully understood. We designed the present retrospective study to investigate the factors affecting the prognosis of SDC and the effects of adjuvant therapies on the clinical outcomes of patients. MATERIALS AND METHODS: Patients with SDC treated surgically from 2006 to 2016 were enrolled in the present retrospective cohort study. The demographic data, clinical pathologic characteristics, and follow-up results were recorded...
February 19, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29542209/association-of-overexpressed-karyopherin-alpha-2-with-poor-survival-and-its-contribution-to-interleukin-1%C3%AE-induced-matrix-metalloproteinase-expression-in-oral-cancer
#10
Chun-I Wang, Chia-Jung Yu, Yenlin Huang, Jui-Shan Yi, Hsing-Wen Cheng, Huang-Kai Kao, William Wei-Kai Lao, Kai-Ping Chang
BACKGROUND: The purpose of this study was to elucidate the clinicopathological associations and molecular mechanisms of karyopherin alpha 2 (KPNA2) in oral cavity squamous cell carcinoma (SCC) progression. METHODS: The KPNA2 expressions were analyzed by immunohistochemistry and enzyme-linked immunosorbent assay in 209 tissues and 181 saliva samples, respectively. The functions of KPNA2 in migration and invasion were examined in KPNA2-knowdown cells. The matrix metalloproteinase (MMP) levels were determined by real-time quantitative polymerase chain reaction (qPCR)...
March 15, 2018: Head & Neck
https://www.readbyqxmd.com/read/29536123/-staging-of-oropharyngeal-carcinomas-new-tnm-classification-as-a-challenge-for-head-and-neck-cancer-centers
#11
REVIEW
A Beltz, D Gösswein, S Zimmer, R H Stauber, J Hagemann, S Strieth, C Matthias, J Künzel
BACKGROUND: The TNM (tumor, nodes, metastasis) classification is updated periodically according to the literature and international recommendations. With the 8th edition, notable changes have been developed especially with regard to oropharyngeal cancer. MATERIALS AND METHODS: The modifications as well as the practicability of the classification for staging of oropharyngeal cancers are demonstrated on the basis of cases from the tumor database. RESULTS: The latest edition of the TNM classification realizes requirements to differentiate between human papilloma virus (HPV) positive and HPV-negative tumors during staging...
March 13, 2018: HNO
https://www.readbyqxmd.com/read/29518976/ebv-positive-lymphoproliferations-of-b-t-and-nk-cell-derivation-in-non-immunocompromised-hosts
#12
REVIEW
Stefan D Dojcinov, Falko Fend, Leticia Quintanilla-Martinez
The contribution of Epstein-Barr virus (EBV) to the development of specific types of benign lymphoproliferations and malignant lymphomas has been extensively studied since the discovery of the virus over the last 50 years. The importance and better understanding of the EBV-associated lymphoproliferative disorders (LPD) of B, T or natural killer (NK) cell type has resulted in the recognition of new entities like EBV+ mucocutaneous ulcer or the addition of chronic active EBV (CAEBV) infection in the revised 2016 World Health Organization (WHO) lymphoma classification...
March 7, 2018: Pathogens
https://www.readbyqxmd.com/read/29504987/isolated-skeletal-muscle-recurrence-of-an-originally-nodal-diffuse-large-b-cell-lymphoma-a-case-report-and-review-of-the-literature
#13
REVIEW
Nikolaos Spetsieris, Nefeli Giannakopoulou, Eleni Variami, Konstantinos Zervakis, Niki Rougala, Georgios Garefalakis, Vasiliki Skarlatou, Nora-Athina Viniou, Panagiotis Diamantopoulos
RATIONALE: Diffuse large B cell lymphoma (DLBCL) is a malignancy of the B cells with extranodal primary involvement being estimated at 30% to 40% of cases. Primary skeletal muscle presentation of DLBCL is extremely rare, with an estimated incidence of about 0.5% of extranodal lymphomas, presenting mostly in the lower extremities. The possible mechanisms of muscle involvement of DLBCL include primary extranodal disease, extension from adjacent organs (such as lymph nodes) or disseminated disease...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29496065/neck-recurrence-in-clinically-node-negative-oral-cancer-27-year-experience-at-a-single-institution
#14
Aviram Mizrachi, Jocelyn C Migliacci, Pablo H Montero, Sean McBride, Jatin P Shah, Snehal G Patel, Ian Ganly
OBJECTIVES: Neck failure in patients with oral squamous cell carcinoma (OSCC) carries a poor outcome, yet the management of patients who initially present with clinically node-negative (cN0) neck is not clearly defined. PATIENTS AND METHODS: Retrospective review of patients with cN0 OSCC treated at Memorial Sloan Kettering Cancer Center from 1985 to 2012, focusing on rate, pattern and predictors of neck failure, salvage treatment, and survival outcomes. RESULTS: Of 1,302 patients, 806 (62%) underwent elective neck dissection (END) and 496 (38%) had observation...
March 2018: Oral Oncology
https://www.readbyqxmd.com/read/29488161/role-of-pet-mri-in-oral-cavity-and-oropharyngeal-cancers-based-on-the-8th-edition-of-the-ajcc-cancer-staging-system-a-pictorial-essay
#15
Tetsuya Tsujikawa, Norihiko Narita, Masafumi Kanno, Tetsuji Takabayashi, Shigeharu Fujieda, Hidehiko Okazawa
The American Joint Committee on Cancer (AJCC) released the 8th edition of the AJCC cancer staging manual in 2017 that includes significant modifications from the 7th edition in the sections on oral cavity cancer (OCC) and oropharyngeal cancer (OPC). These highlights comprise the incorporation of the depth of invasion and exclusion of extrinsic tongue muscle involvement in the T staging of OCC, the separation of OPC staging based on the high-risk human papilloma virus status, and the inclusion of extranodal extension in N staging...
May 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29484690/lymphomas-and-thyroid-bridging-the-gap
#16
REVIEW
Salvatrice Mancuso, Melania Carlisi, Mariasanta Napolitano, Sergio Siragusa
The thyroid gland is often involved in the development of neoplastic diseases, including lymphoproliferative disorders. The aim of this paper is to provide a comprehensive overview of the multiple interactions between lymphoma and thyroid. Through an extensive research among the literature, the relationship between lymphomas and thyroid can be established at various levels, and the possible interconnections are here summarized in 5 points: (1) the greater risk of lymphoma development in some thyroid diseases; (2) the primary thyroid lymphoma, with focus on issues related to the diagnosis, differential diagnosis, and treatment; (3) the incidence of thyroid involvement in primitive nodal lymphomas or in extranodal lymphomas of the other sites; (4) thyroid changes after treatment of lymphoma, in relation to the effects of radiation therapy and immuno-chemotherapy; (5) the incidental findings of thyroid changes, on imaging, in patients with lymphoma, without a direct involvement of the gland in malignant disease...
February 27, 2018: Hematological Oncology
https://www.readbyqxmd.com/read/29462007/risk-factors-for-recurrence-after-treatment-of-n1b-papillary-thyroid-carcinoma
#17
Sang Hun Lee, Jong-Lyel Roh, Gyungyup Gong, Kyung-Ja Cho, Seung-Ho Choi, Soon Yuhl Nam, Sang Yoon Kim
OBJECTIVES: To examine risk factors for posttreatment recurrence in papillary thyroid carcinoma (PTC) patients with initial presentation of lateral neck metastasis (N1b). SUMMARY OF BACKGROUND DATA: N1b PTC recurs after definitive treatment. METHODS: Study subjects were 437 consecutive PTC patients who underwent total thyroidectomy and therapeutic neck dissection of central and lateral compartments and postoperative radioactive iodine ablation therapy...
February 16, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29452667/overview-on-the-management-of-non-gastric-malt-lymphomas
#18
REVIEW
Irene Defrancesco, Luca Arcaini
Extranodal marginal zone B-cell lymphomas (EMZLs) of the mucosa-associated lymphoid tissue (MALT) are indolent lymphomas which can present at any extranodal site. The most frequent localizations (other than stomach) are ocular adnexa, salivary gland, skin, lung and thyroid. Chronic inflammation and antigenic stimulation are a potential risk for the development of MALT lymphomas. While Helicobacter Pylori (HP) is known to be associated with gastric MALT lymphoma and antibiotic therapy is effective in the setting of HP-positive, other microorganisms (such as Chlamydophila Psittaci, Campylobacter Jejiuni, Borrelia Burgdoferi) have been implicated in the pathogenesis of non-gastric MALT lymphomas...
March 2018: Best Practice & Research. Clinical Haematology
https://www.readbyqxmd.com/read/29445865/risk-of-recurrence-in-a-homogeneously-managed-pt3-differentiated-thyroid-carcinoma-population
#19
Nathalie Chereau, Etienne Dauzier, Gaëlle Godiris-Petit, Séverine Noullet, Isabelle Brocheriou, Laurence Leenhardt, Camille Buffet, Fabrice Menegaux
BACKGROUND: International guidelines for the management of differentiated thyroid cancers are based on the 7th TNM classification: pT3 tumors are defined as differentiated thyroid cancers (DTCs) measuring more than 4 cm in their greatest dimension that are limited to the thyroid or any tumor with minimal extrathyroidal extension (ETE; sternothyroid muscle or perithyroid soft tissues). Differences in clinicohistological features and prognosis among patients with pT3 tumors remain controversial, and studies regarding pT3 subgroups are lacking...
February 14, 2018: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29434908/extranodal-presentation-of-hodgkin-s-lymphoma-of-the-sternum-a-case-report-and-review-of-the-literature
#20
Yan Li, You Qin, Liduan Zheng, Hong Liu
Hodgkin's lymphoma (HL) is typically a systemic disease with involvement of the cervical, supraclavicular and mediastinal lymph nodes. An extra-nodal presentation of HL is unusual and seldom encountered in the clinic. The most common sites of presentation for extra-nodal extension are the spleen, liver, lungs, bones and marrow. The bones that are frequently involved are the vertebrae, pelvis, ribs and femur. Involvement of the sternum has occasionally been reported. The current study presents an unusual case on the extra-nodal presentation of HL of the sternum arising in a 25-year-old woman, and reviews the relevant literature with particular emphasis on treatment...
February 2018: Oncology Letters
keyword
keyword
90688
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"