Sanat Phatak, Pranav Mahadevkar, Kaustubh Suresh Chaudhari, Shreya Chakladar, Swasti Jain, Smita Dhadge, Sarita Jadhav, Rohan Shah, Aboli Bhalerao, Anupama Patil, Jennifer L Ingram, Pranay Goel, Chittaranjan S Yajnik
AIMS: Diabetic cheiroarthropathies limit hand mobility due to fibrosis and could be markers of a global profibrotic trajectory. Heterogeneity in definitions and lack of a method to measure it complicate studying associations with organ involvement and treatment outcomes. We measured metacarpophalangeal (MCP) joint extension as a metric and describe magnetic resonance (MR) imaging determinants of MCP restriction. METHODS: Adults with type 1 diabetes were screened for hand manifestations using a symptom questionnaire, clinical examination, and function [Duruoz hand index (DHI) and grip strength]...
2023: Frontiers in Endocrinology