keyword
MENU ▼
Read by QxMD icon Read
search

IV antibiotics

keyword
https://www.readbyqxmd.com/read/29148895/characterization-of-cefotaxime-and-ciprofloxacin-resistant-commensal-escherichia-coli-originating-from-belgian-farm-animals-indicates-high-antibiotic-resistance-transfer-rates
#1
Ellen Lambrecht, Eva Van Meervenne, Nico Boon, Tom Van de Wiele, Pierre Wattiau, Lieve Herman, Marc Heyndrickx, Els Van Coillie
Food-producing animals represent one of the sources of antibiotic resistant commensal bacteria. There is an increasing awareness that these bacteria might have the potential to transfer their resistance genes to other (pathogenic) bacteria. In this study, 50 commensal Escherichia coli strains originating from food-producing animals and resistant to the "highest priority, critically important antibiotics" cefotaxime and/or ciprofloxacin, were selected for further characterization. For each strain (i) an antibiogram, (ii) the phylogenetic group, (iii) plasmid replicon type, (iv) presence and identification of integrons, and (v) antibiotic resistance transfer ratios were determined...
November 17, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/29147962/retrospective-review-of-ceftriaxone-versus-levofloxacin-for-treatment-of-e-coli-urinary-tract-infections
#2
Samantha S Wang, Patrick D Ratliff, William R Judd
Background Urinary tract infections (UTIs) are among the most common bacterial infections. Options for initial treatment of pyelonephritis or UTI requiring hospitalization include levofloxacin (LVF) or extended-spectrum cephalosporins. Globally, uropathogenic Escherichia coli resistance rates to fluoroquinolones have increased in recent years. Objective To compare clinical outcomes of patients receiving ceftriaxone (CTX) to those who received LVF empirically for the treatment of E. coli UTI. Setting 433-bed community hospital in Lexington, KY...
November 17, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29144242/effects-of-intrapartum-antibiotic-prophylaxis-on-neonatal-acquisition-of-group-b-streptococci
#3
Meiwa Toyofuku, Miyuki Morozumi, Mariko Hida, Yoshitake Satoh, Hiroshi Sakata, Hiroyuki Shiro, Kimiko Ubukata, Mitsuru Murata, Satoshi Iwata
OBJECTIVES: To assess the incidence of colonization with group B streptococci (GBS) among neonates as influenced by maternal GBS carriage and intrapartum antibiotic prophylaxis (IAP). STUDY DESIGN: Between October 2014 and May 2015, nasopharyngeal and rectal swab samples were collected from 730 neonates at 1 week and 1 month after birth. GBS and capsular serotype were identified by real-time polymerase chain reaction and by culture. IAP at delivery was determined retrospectively from hospital records...
November 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29136035/comparative-efficacy-and-safety-of-antibiotics-used-to-treat-acute-bacterial-skin-and-skin-structure-infections-results-of-a-network-meta-analysis
#4
Julian F Guest, Jaime Esteban, Anton G Manganelli, Andrea Novelli, Giuliano Rizzardini, Miquel Serra
OBJECTIVE: This NMA compared the efficacy and safety between IV antibiotics that are used in the current standard of care for managing adult patients (≥18 years of age) with ABSSSI. METHODS: Comparators were chosen on the basis that both direct and indirect comparisons between the interventions of interest could be performed. Outcomes of the analysis were selected on the basis that they are frequently measured and reported in trials involving ABSSSI patients, and only published randomised control trials of any size and duration and with any blinding status were eligible for inclusion in the analysis...
2017: PloS One
https://www.readbyqxmd.com/read/29133050/newly-designed-organotin-iv-carboxylates-with-peptide-linkage-synthesis-structural-elucidation-physicochemical-characterizations-and-pharmacological-investigations
#5
Muhammad Sirajuddin, Vickie McKee, Muhammad Tariq, Saqib Ali
Fourteen new organotin(IV) carboxylate complexes with peptide linkage of (2-(4-methoxy-2-nitrophenylcarbamoyl)benzoic acid) were successfully synthesized and characterized by elemental analyses, FT-IR, NMR ((1)H, (13)C and (119)Sn) and single crystal X-ray techniques. FT-IR results of the sodium salt of 2-(4-methoxy-2-nitrophenylcarbamoyl)benzoic acid and complexes showed that the coordination took place via oxygen atoms of the carboxylate group. (1)J((119)Sn-(13)C), (2)J((119)Sn-(1)H) and θ values calculated from (1)H and (13)C NMR data using Lockhart's equation reveal a trigonal bipyramidal geometry for triorganotin(IV) derivatives and an octahedral geometry for diorganotin(IV) derivatives...
November 4, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29125851/new-evidence-showing-that-the-destruction-of-gut-bacteria-by-antibiotic-treatment-could-increase-the-honey-bee-s-vulnerability-to-nosema-infection
#6
Jiang Hong Li, Jay D Evans, Wen Feng Li, Ya Zhou Zhao, Gloria DeGrandi-Hoffman, Shao Kang Huang, Zhi Guo Li, Michele Hamilton, Yan Ping Chen
It has become increasingly clear that gut bacteria play vital roles in the development, nutrition, immunity, and overall fitness of their eukaryotic hosts. We conducted the present study to investigate the effects of gut microbiota disruption on the honey bee's immune responses to infection by the microsporidian parasite Nosema ceranae. Newly emerged adult workers were collected and divided into four groups: Group I-no treatment; Group II-inoculated with N. ceranae, Group III-antibiotic treatment, and Group IV-antibiotic treatment after inoculation with N...
2017: PloS One
https://www.readbyqxmd.com/read/29124834/prevalence-and-characterization-of-staphylococcus-aureus-causing-community-acquired-skin-and-soft-tissue-infections-on-java-and-bali-indonesia
#7
Dewi Santosaningsih, Sanarto Santoso, Nanik Setijowati, Harun A Rasyid, Nyoman S Budayanti, Ketut Suata, Dicky B Widhyatmoko, Priyo B Purwono, Kuntaman Kuntaman, Damayanti Damayanti, Cita R S Prakoeswa, Mitchell Laurens, Josephine W I van Nierop, Geraldine L Nanninga, Neline Oudenes, Michelle de Regt, Susan V Snijders, Henri A Verbrugh, Juliëtte A Severin
OBJECTIVES: To define the role of Staphylococcus aureus in community settings among patients with skin and soft tissue infections (SSTI) in Indonesia. METHODS: S. aureus were cultured from anterior nares, throat, and wounds of 567 ambulatory patients presenting with SSTI. The mecA gene and genes encoding Panton-Valentine leukocidin (PVL; lukF-PV and lukS-PV) and exfoliative toxin (ET; eta and etb) were determined by PCR. Clonal relatedness among methicillin-resistant S...
November 10, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29119077/osteomyelitis-of-the-pelvic-bones-a-multidisciplinary-approach-to-treatment
#8
Maria Dudareva, Jamie Ferguson, Nicholas Riley, David Stubbs, Bridget Atkins, Martin McNally
Background and Purpose: A case series review of chronic pelvic osteomyelitis treated with combined medical and surgical treatment by a multidisciplinary team. Methods: All patients treated with surgical excision of pelvic osteomyelitis at our tertiary referral centre between 2002 and 2014 were included. All received combined care from a clinical microbiologist, an orthopaedic surgeon and a plastic surgeon. The rate of recurrent infection, wound healing problems and post-operative mortality was determined in all...
2017: Journal of bone and joint infection
https://www.readbyqxmd.com/read/29115289/synthesis-and-antibacterial-activity-of-novel-lincomycin-derivatives-iv-optimization-of-an-n-6-substituent
#9
Ko Kumura, Yoshinari Wakiyama, Kazutaka Ueda, Eijiro Umemura, Yoko Hirai, Keiko Yamada, Keiichi Ajito
The design and synthesis of lincomycin derivatives modified at the C-6 and C-7 positions are described. A substituent at the C-7 position is a 5-aryl-1,3,4-thiadiazol-2-yl-thio group that generates antibacterial activities against macrolide-resistant Streptococcus pneumoniae and Streptococcus pyogenes carrying an erm gene. An additional modification at the C-6 position was explored in application of information regarding pirlimycin and other related compounds. These dual modifications were accomplished by using methyl α-thiolincosaminide as a starting material...
November 8, 2017: Journal of Antibiotics
https://www.readbyqxmd.com/read/29114639/knee-septic-arthritis-after-arthroscopy-incidence-risk-factors-functional-outcome-and-infection-eradication-rate
#10
REVIEW
G Balato, S L Di Donato, T Ascione, A D'Addona, F Smeraglia, G Di Vico, D Rosa
Purpose  Septic knee arthritis following arthroscopy is a rare but dreaded complication. Definition and management of knee deep infections are quite discussed in literature. In this review, literature regarding infections after knee arthroscopy is analyzed highlighting the incidence, causative bacteria, risk factors as well as clinical outcomes. Methods  We performed a review of the literature matching the following key words: "septic arthritis" OR "infection" AND "arthroscopy" AND "knee." Knee arthroscopic procedures, such as debridement, meniscectomy, meniscus repair, synovectomy, microfracture, and lateral release, were considered...
June 2017: Joints
https://www.readbyqxmd.com/read/29110867/characterization-of-sccmec-and-spa-types-of-methicillin-resistant-staphylococcus-aureus-isolates-from-health-care-and-community-acquired-infections-in-kerman-iran
#11
Yaser Fasihi, Somayeh Kiaei, Davood Kalantar-Neyestanaki
Spread of methicillin-resistant Staphylococcus aureus (MRSA) isolates is a worldwide problem. Molecular typing is a useful tool to understand MRSA epidemiology. Herein, we determined vancomycin-resistant, SCCmec and spa types among MRSA isolates recovered from healthcare and community-acquired infections in Kerman, Iran. A total of 170 S. aureus isolates were collected from different patients who were admitted to affiliated hospitals of Kerman University of Medical science. MRSA and vancomycin-resistant S. aureus (VRSA) isolates were detected by phenotypic methods...
December 2017: Journal of Epidemiology and Global Health
https://www.readbyqxmd.com/read/29107868/growth-performance-carcass-quality-fresh-belly-characteristics-and-commercial-bacon-slicing-yields-of-growing-finishing-pigs-fed-a-subtherapeutic-dose-of-an-antibiotic-a-natural-antimicrobial-or-not-fed-an-antibiotic-or-antimicrobial
#12
J E Lowell, B M Bohrer, K B Wilson, M F Overholt, B N Harsh, H H Stein, A C Dilger, D D Boler
The objective was to compare growth performance, belly characteristics, and bacon slicing yields of growing-finishing pigs fed a subtherapeutic dose of an antibiotic, a natural antimicrobial, or a diet containing no antibiotics or antimicrobials. Barrows and gilts (96 each, initial BW: 27.52±3.98kg) were housed in 48 pens (8 replications per treatment) in a 2×3 factorial randomized complete block design. Pens were assigned 1 of 3 diets: antibiotic free, oregano or tylosin phosphate. Pigs were slaughtered at an average BW of 127...
October 18, 2017: Meat Science
https://www.readbyqxmd.com/read/29107789/overcoming-the-challenges-of-low-drug-solubility-in-the-intravenous-formulation-of-solithromycin
#13
Daniel Evans, Samuel Yalkowsky, Sara Wu, David Pereira, Prabha Fernandes
Solithromycin is a fluoro-ketolide (a fourth-generation macrolide) antibiotic that has been undergoing clinical trials for the treatment of community acquired bacterial pneumonia. In this study, development of the tri-amino acid buffered solithromycin intravenous (IV) formulation was performed to minimize the occurrence of infusion associated local adverse events (infusion site pain or phlebitis) observed in patients who received the tartaric acid buffered IV formulation with a lower buffered capacity during Phase I clinical trials...
October 28, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29104387/evaluation-of-antimicrobial-efficacy-of-various-intracanal-medicaments-in-primary-teeth-an-in-vivo-study
#14
Brahmananda Dutta, Kanika S Dhull, Debasmita Das, P V Samir, Rajnish K Verma, Nipa Singh
Introduction: Bacteria and their products play a primary etiological role in the initiation and perpetuation of pulpoperiapical pathosis. Intracanal medication is important for endodontic success as it eliminates microorganisms that persist after chemomechanical preparation. Aim: To compare antimicrobial efficacy of calcium hydroxide powder, triple antibiotic paste, calcium hydroxide with 2% chlorhexidine solution, and triple antibiotic paste with 2% chlorhexidine solution...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29102103/frequency-antimicrobial-susceptibility-and-clonal-distribution-of-methicillin-resistant-staphylococcus-pseudintermedius-in-canine-clinical-samples-submitted-to-a-veterinary-diagnostic-laboratory-in-italy-a-3-year-retrospective-investigation
#15
G Ventrella, A Moodley, E Grandolfo, A Parisi, M Corrente, D Buonavoglia, L Guardabassi
In the last decade there has been a rapid global spread of methicillin-resistant Staphylococcus pseudintermedius (MRSP) clones displaying multidrug resistance in dogs. We investigated prevalence, antimicrobial susceptibility and clonal distribution of MRSP isolated from clinical canine samples between during 2011-2014. Following species identification by nuc PCR, MRSP were confirmed by the presence of mecA and characterized by antimicrobial susceptibility testing, Pulsed Field Gel Electrophoresis (PFGE), SCCmec typing, and Multi-Locus Sequence Typing (MLST) of a few isolates having distinct PFGE profiles...
November 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/29101199/antifungal-hsaf-biosynthesis-in-lysobacter-enzymogenes-is-controlled-by-the-interplay-of-two-transcription-factors-and-a-diffusible-molecule
#16
Zhenhe Su, Sen Han, Zhengqing Fu, Guoliang Qian, Fengquan Liu
Lysobacter enzymogenes is a Gram-negative, environmental ubiquitous bacterium that produces a secondary metabolite, called HSAF (Heat-stable antifungal factor), as an antifungal factor against plant and animal fungal pathogens. 4-hydroxybenzoic acid (4-HBA) is a newly identified diffusible factor that regulates HSAF synthesis via LysRLe, a LysR-type transcription factor (TF). Here, to identify additional TFs within the 4-HBA regulatory pathway that control HSAF production, we re-analyzed the LenB2-based transcriptomic data, in which LenB2 is the enzyme responsible for 4-HBA production...
November 3, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29097611/trends-in-intravenous-antibiotic-duration-for-urinary-tract-infections-in-young-infants
#17
William W Lewis-de Los Angeles, Cary Thurm, Adam L Hersh, Samir S Shah, Michael J Smith, Jeffrey S Gerber, Sarah K Parker, Jason G Newland, Matthew P Kronman, Brian R Lee, Thomas V Brogan, Joshua D Courter, Alicen Spaulding, Sameer J Patel
OBJECTIVES: To assess trends in the duration of intravenous (IV) antibiotics for urinary tract infections (UTIs) in infants ≤60 days old between 2005 and 2015 and determine if the duration of IV antibiotic treatment is associated with readmission. METHODS: Retrospective analysis of infants ≤60 days old diagnosed with a UTI who were admitted to a children's hospital and received IV antibiotics. Infants were excluded if they had a previous surgery or comorbidities, bacteremia, or admission to the ICU...
November 2, 2017: Pediatrics
https://www.readbyqxmd.com/read/29095181/intravenous-push-cephalosporin-antibiotics-in-the-emergency-department-a-practice-improvement-project
#18
Julie M McLaughlin, Robin A Scott, Stephanie L Koenig, Scott W Mueller
Delays in administration of appropriate antibiotics to patients with septic shock are associated with increased mortality. To improve the care of patients with sepsis within our 73-bed emergency department (ED), a "first-dose" intravenous push (IVP) cephalosporin antibiotic protocol was initiated. This project was aimed at improving the time from provider order of antibiotic to administration, which follows the Sepsis Core Measure of timely antibiotic administration.This was a single-center, retrospective analysis of a practice improvement study...
October 2017: Advanced Emergency Nursing Journal
https://www.readbyqxmd.com/read/29093233/optimal-amikacin-levels-for-patients-with-sepsis-in-intensive-care-unit-of-cipto-mangunkusumo-hospital-jakarta-indonesia
#19
Gestina Aliska, Rianto Setiabudy, Purwantyastuti Purwantyastuti, Anis Karuniawati, Rudyanto Sedono, Trisni U Dewi, Muhammad K Azwar
BACKGROUND: Amikacin is one of the antibiotics of choice for sepsis and septic shock. Pharmacokinetic of amikacin can be influenced by septic condition with subsequent effect on its pharmacodynamic. At Cipto Mangunkusumo Hospital (RSCM), Jakarta, adult patients in the ICU were given standard amikacin dose of 1 g/day, however the achievement of optimal plasma level had never been evaluated. This study aimed to evaluate whether the optimal plasma level of amikacin was achieved with the use of standard dose in septic conditions...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29088985/anticonvulsant-effect-of-gentamicin-on-the-seizures-induced-by-kainic-acid
#20
Yuxiao Zhao, Ziyi Wang, Wenwen Lao, Ping Kuang, Nan Jiang, Tao Yin, Weide Lin, Hongyan Zhu, Yonghua Ji
OBJECTIVE:  Epilepsy is a chronic neurological disorder affecting approximately 0.5-2% of the population worldwide. Gentamicin (GM) is an aminoglycoside antibiotic used to treat several types of bacterial infections. We investigate whether the administration of GM can reduce seizures in temporal lobe epilepsy (TLE). METHODS: The animal model of temporal lobe epilepsy (TLE) was established by kainic acid (KA) intrahippocampal injection. Behavioral test and Electroencephalography (EEG) recordings were performed to detect the effects of GM on the seizures triggered by KA injection in rats...
October 31, 2017: Neurological Research
keyword
keyword
90663
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"