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https://www.readbyqxmd.com/read/29457342/soft-tissue-balancing-in-total-knee-arthroplasty-using-sensor-guided-assessment-is-there-a-learning-curve
#1
Monther A Gharaibeh, Darren B Chen, Samuel J MacDessi
BACKGROUND: Sensor-guided assessment for soft tissue balance in total knee arthroplasty (TKA) has been reported to improve patient satisfaction and self-reported outcome scores. As more surgeons adopt this technology in TKA, we performed this study to identify if there is a learning curve with its use. METHODS: Analysis of a total of 90 consecutive cases was performed in this study. Initial and final intercompartmental pressure differences were recorded before and after knee ligament balancing...
February 18, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29456941/the-learning-curve-in-surgical-practice-and-its-applicability-to-rhinoplasty
#2
Aditya Yeolekar, Haris Qadri
The learning curve as a concept has been considered, discussed and debated in medical education and healthcare for over two decades. The precise usage has been recognised in surgical disciplines both broad specialties and sub-specialties. Rollin Daniel in his book stated that, rhinoplasty is the most difficult of all cosmetic operations for three reasons, (a) nasal anatomy is highly variable, (b) the procedure must correct form and function and (c) the final result must meet the patients expectations. With this in mind a study was carried on the perception of learning curve in rhinoplasty based on a surgeon questionnaire at Marien Hospital, Stuttgart, Germany under Prof...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29455962/needle-localization-of-small-pulmonary-nodules-lessons-learned
#3
Patricia A Thistlethwaite, Jonathan R Gower, Moises Hernandez, Yu Zhang, Andrew C Picel, Anne C Roberts
BACKGROUND: Lung nodules that are small and deep within lung parenchyma, and have semisolid characteristics are often challenging to localize with video-assisted thoracoscopic surgery (VATS). We describe our cumulative experience using needle localization of small nodules before surgical resection. We report procedural tips, operative results, and lessons learned over time. METHODS: A retrospective review of all needle localization cases between July 1, 2006, and December 30, 2016, at a single institution was performed...
January 17, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29455760/developing-a-partnership-for-change-the-national-collaborative-on-childhood-obesity-research
#4
The Writing Group For The National Collaborative On Childhood Obesity Research Nccor
Rising obesity rates in the U.S. over the past several decades, particularly among children and adolescents, led to an increased focus on research addressing obesity prevention and public- and private-sector initiatives on healthy eating and physical activity. Groups conducting prevention initiatives recognized that their ability to achieve and sustain cross-sector environmental, policy, and systems-level solutions was hampered by limited evidence in those areas. In 2007, the Centers for Disease Control and Prevention, NIH, and the Robert Wood Johnson Foundation began to discuss forming a partnership that could accelerate progress to prevent childhood obesity by coordinating research and evaluation agendas and collaboratively building an evidence base...
March 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29455350/analysing-the-accuracy-of-machine-learning-techniques-to-develop-an-integrated-influent-time-series-model-case-study-of-a-sewage-treatment-plant-malaysia
#5
Mozafar Ansari, Faridah Othman, Taher Abunama, Ahmed El-Shafie
The function of a sewage treatment plant is to treat the sewage to acceptable standards before being discharged into the receiving waters. To design and operate such plants, it is necessary to measure and predict the influent flow rate. In this research, the influent flow rate of a sewage treatment plant (STP) was modelled and predicted by autoregressive integrated moving average (ARIMA), nonlinear autoregressive network (NAR) and support vector machine (SVM) regression time series algorithms. To evaluate the models' accuracy, the root mean square error (RMSE) and coefficient of determination (R2 ) were calculated as initial assessment measures, while relative error (RE), peak flow criterion (PFC) and low flow criterion (LFC) were calculated as final evaluation measures to demonstrate the detailed accuracy of the selected models...
February 17, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29454718/the-learning-curve-for-robot-assisted-minimally-invasive-thoracoscopic-esophagectomy-results-from-312-cases
#6
Pieter C van der Sluis, Jelle P Ruurda, Sylvia van der Horst, Lucas Goense, Richard van Hillegersberg
BACKGROUND: Robot-assisted minimally invasive thoraco-laparoscopic esophagectomy (RAMIE) was developed in 2003. RAMIE was shown to be safe and oncologically effective. The aim of this study was to assess the learning curve and the proctoring program for a newly introduced surgeon (surgeon 2). METHODS: The "learning curve" was defined as the number of operations that must be performed by a surgeon to achieve a steady level of performance. Measures of proficiency to describe the learning curve of the proctor and the newly introduced surgeon 2 included: operating time, blood loss and conversion rates and were analyzed using the cumulative sum (CUSUM) method...
February 15, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29454643/proprioceptive-stimuli-and-habit-formation-interresponse-time-mediated-behavior-in-cd-1-mice
#7
J Mark Cleaveland, Anna Roselle, Delaney K Fischer
The consolidation of behavioral sequences into relatively ballistic habits is thought to involve the formation of stimulus - response associations. Typically, the stimuli in these associations are assumed to be exteroceptive, i.e., external to the organism. However, responses, themselves, also possess stimulus properties that can mediate behavior. Indeed, these "proprioceptive cues" have long been hypothesized to underlie habit formation (Hull, 1934a, 1934b). One such stimulus involves the time durations between responses - a stimulus termed interresponse time (IRT)...
February 15, 2018: Behavioural Processes
https://www.readbyqxmd.com/read/29453728/single-site-port-robotic-assisted-hysterectomy-an-update
#8
REVIEW
Christos Iavazzo, Evelyn Eleni Minis, Ioannis D Gkegkes
Single-incision approach in robotic gynecology is a relatively new concept. The role of single-port systems in robotic hysterectomy, their advantages and disadvantages, as well as the technical challenges, are still under investigation. A systematic review was performed by searching in PubMed and Scopus databases. In 810 out of 1225 patients, hysterectomy was performed for non-neoplastic disease. Single-Site ® was the most common port system. Duration of the procedure and relative blood loss ranged from 60 to 311 min and 7 to 750 ml, respectively...
February 16, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29453119/an-analysis-of-environmental-incidents-for-a-national-antarctic-program
#9
Shaun T Brooks, Julia Jabour, Andy J Sharman, Dana M Bergstrom
Research stations in Antarctica are concentrated on scarce ice-free habitats. Operating these stations in the harsh Antarctic climate provides many challenges, including the need to handle bulk fuel and cargo increasing the risk of environmental incidents. We examined 195 reports of environmental incidents from the Australian Antarctic Program, spanning six years, to investigate the impacts and pathways of contemporary environmental incidents. Fuel and chemical spills were most common, followed by biosecurity incursions...
February 13, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29452755/machine-learning-algorithms-based-on-signals-from-a-single-wearable-inertial-sensor-can-detect-surface-and-age-related-differences-in-walking
#10
B Hu, P C Dixon, J V Jacobs, J T Dennerlein, J M Schiffman
The aim of this study was to investigate if a machine learning algorithm utilizing triaxial accelerometer, gyroscope, and magnetometer data from an inertial motion unit (IMU) could detect surface- and age-related differences in walking. Seventeen older (71.5 ± 4.2 years) and eighteen young (27.0 ± 4.7 years) healthy adults walked over flat and uneven brick surfaces wearing an inertial measurement unit (IMU) over the L5 vertebra. IMU data were binned into smaller data segments using 4-s sliding windows with 1-s step lengths...
January 12, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29452517/a-decade-of-the-clinical-trials-transformation-initiative-what-have-we-accomplished-what-have-we-learned
#11
P Tenaerts, L Madre, M Landray
The Clinical Trials Transformation Initiative reflects on 10 years of working to improve the quality and efficiency of clinical trials. This article highlights many of the Clinical Trials Transformation Initiative's accomplishments and offers examples of the impact that the Clinical Trials Transformation Initiative has had on the clinical trials enterprise. After conducting more than 25 projects and issuing recommendations for specific strategies to improve the design and execution of clinical trials, some common themes and lessons learned have emerged...
February 2018: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/29452334/seed-2-a-user-friendly-platform-for-amplicon-high-throughput-sequencing-data-analyses
#12
Tomáš Vetrovský, Petr Baldrian, Daniel Morais, Bonnie Berger
Motivation: Modern molecular methods have increased our ability to describe microbial communities. Along with the advances brought by new sequencing technologies, we now require intensive computational resources to make sense of the large numbers of sequences continuously produced. The software developed by the scientific community to address this demand, although very useful, require experience of the command-line environment, extensive training and have steep learning curves, limiting their use...
February 14, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29452284/-micro-endoscopic-vs-pure-endoscopic-surgery-for-spinal-intra-dural-mass-lesions-a-comparative-study-and-review
#13
Sivashanmugam Dhandapani, Madhivanan Karthigeyan
BACKGROUND: Endoscopy is increasingly being used for minimal invasiveness and panoramic visualization, with unclear efficacy and safety among spinal intradural lesions. OBJECTIVE: To compare micro-endoscopic and pure-endoscopic surgery for spinal intradural lesions. METHODS: Spinal intradural lesions operated by us using endoscopic/access ports were categorized 'micro-endoscopic' (predominant microscope use), or 'pure-endoscopic' (standalone endoscopy) surgery, and studied with respect to clinico-radiological features, techniques, peri-operative course, histopathology, clinical and radiological outcome at minimum of 3 months...
February 13, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29450713/radiomic-signature-as-a-diagnostic-factor-for-histologic-subtype-classification-of-non-small-cell-lung-cancer
#14
Xinzhong Zhu, Di Dong, Zhendong Chen, Mengjie Fang, Liwen Zhang, Jiangdian Song, Dongdong Yu, Yali Zang, Zhenyu Liu, Jingyun Shi, Jie Tian
OBJECTIVES: To distinguish squamous cell carcinoma (SCC) from lung adenocarcinoma (ADC) based on a radiomic signature METHODS: This study involved 129 patients with non-small cell lung cancer (NSCLC) (81 in the training cohort and 48 in the independent validation cohort). Approximately 485 features were extracted from a manually outlined tumor region. The LASSO logistic regression model selected the key features of a radiomic signature. Receiver operating characteristic curve and area under the curve (AUC) were used to evaluate the performance of the radiomic signature in the training and validation cohorts...
February 15, 2018: European Radiology
https://www.readbyqxmd.com/read/29450642/risk-factors-of-non-specific-spinal-pain-in-childhood
#15
Julia Szita, Sara Boja, Agnes Szilagyi, Annamaria Somhegyi, Peter Pal Varga, Aron Lazary
PURPOSE: Non-specific spinal pain can occur at all ages and current evidence suggests that pediatric non-specific spinal pain is predictive for adult spinal conditions. A 5-year long, prospective cohort study was conducted to identify the lifestyle and environmental factors leading to non-specific spinal pain in childhood. MATERIALS AND METHODS: Data were collected from school children aged 7-16 years, who were randomly selected from three different geographic regions in Hungary...
February 15, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29446758/localized-thin-section-ct-with-radiomics-feature-extraction-and-machine-learning-to-classify-early-detected-pulmonary-nodules-from-lung-cancer-screening
#16
Shu-Ju Tu, Chih-Wei Wang, Kuang-Tse Pan, Yi-Cheng Wu, Chen-Te Wu
Lung cancer screening aims to detect small pulmonary nodules and decrease the mortality rate. However, studies from large-scale clinical trials of lung cancer screening showed false-positive rate is high and positive predictive value is low. To address these problems, it is highly needed to have a technical approach for accurate malignancy differentiation among these early-detected nodules. We studied the clinical feasibility of an additional protocol of localized thin-section CT for further assessment on these recalled patients from lung cancer screening tests...
February 15, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29446035/sorting-through-the-safety-data-haystack-using-machine-learning-to-identify-individual-case-safety-reports-in-social-digital-media
#17
Shaun Comfort, Sujan Perera, Zoe Hudson, Darren Dorrell, Shawman Meireis, Meenakshi Nagarajan, Cartic Ramakrishnan, Jennifer Fine
INTRODUCTION: There is increasing interest in social digital media (SDM) as a data source for pharmacovigilance activities; however, SDM is considered a low information content data source for safety data. Given that pharmacovigilance itself operates in a high-noise, lower-validity environment without objective 'gold standards' beyond process definitions, the introduction of large volumes of SDM into the pharmacovigilance workflow has the potential to exacerbate issues with limited manual resources to perform adverse event identification and processing...
February 14, 2018: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/29445598/small-incisions-major-complications-video-assisted-thoracoscopic-surgery-management-of-intraoperative-complications
#18
William Grossi, Gianluca Masullo, Francesco Londero, Angelo Morelli
The object of our study is to show the causes leading to conversion, in order to observe the responsible variables and analyses if conversion influences the patient's outcome. Between January 2013 and December 2016, Udine Thoracic Department performed 180 video-assisted thoracoscopic surgery (VATS) lobectomies, and 24 cases were converted to thoracotomy due to an intra-operative complication such as arterial or venous bleeding, airway and other injuries. The VATS lobectomies' number increased over the three years: from 27 in 2013 to 55 in 2015 and 48 in 2016...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29445188/daily-circadian-misalignment-impairs-human-cognitive-performance-task-dependently
#19
Sarah L Chellappa, Christopher J Morris, Frank A J L Scheer
Shift work increases the risk for human errors, such that drowsiness due to shift work has contributed to major industrial disasters, including Space Shuttle Challenger, Chernobyl and Alaska Oil Spill disasters, with extraordinary socio-economical costs. Overnight operations pose a challenge because our circadian biology inhibits cognitive performance at night. Yet how the circadian system modulates cognition over multiple days under realistic shift work conditions remains to be established. Importantly, because task-specific cognitive brain regions show different 24-h circadian dynamics, we hypothesize that circadian misalignment impacts cognition task-dependently...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29445116/evaluation-of-3d-heads-up-vitrectomy-outcomes-of-psychometric-skills-testing-and-surgeon-satisfaction
#20
Mario R Romano, Gilda Cennamo, Chiara Comune, Michela Cennamo, Mariantonia Ferrara, Luca Rombetto, Giovanni Cennamo
OBJECTIVES: To evaluate the use of a three-dimensional heads-up microscope (3DM) during 25-gauge pars plana vitrectomy (PPV) compared with a traditional ophthalmic microscope (TM) in terms of efficacy, safety, and teaching and learning satisfaction. METHODS: Prospective comparative interventional study. Fifty eyes affected by one of the following diseases: rhegmatogenous or tractional retinal detachment, epiretinal membrane, full-thickness macular hole, vitreous hemorrhage, or dropped lens...
February 15, 2018: Eye
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