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asymptomatic microscopic hematuria

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https://www.readbyqxmd.com/read/28650895/asymptomatic-microscopic-hematuria-in-women
#1
(no author information available yet)
Asymptomatic microscopic hematuria is an important clinical sign of urinary tract malignancy. Asymptomatic microscopic hematuria has been variably defined over the years. In addition, the evidence primarily is based on data from male patients. However, whether the patient is a man or a woman influences the differential diagnosis of asymptomatic microscopic hematuria, and the risk of urinary tract malignancy (bladder, ureter, and kidney) is significantly less in women than in men. Among women, being older than 60 years, having a history of smoking, and having gross hematuria are the strongest predictors of urologic cancer...
July 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28644736/asymptomatic-microscopic-hematuria-as-a-predictor-of-neoplasia-in-the-urinary-tract
#2
Maria Ordell Sundelin, Jørgen Bjerggaard Jensen
OBJECTIVE: The Danish hematuria guidelines were revised in January 2016. Before revision, it was recommended that asymptomatic microscopic hematuria in patients more than 40 years old should be routinely urologically investigated. In the revised guidelines, patients with asymptomatic microscopic hematuria are not recommended to be investigated, irrespective of age. The purpose of this study was to investigate whether asymptomatic microscopic hematuria was predictive of neoplasia of the urinary tract in a referred cohort of patients...
June 23, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28643107/-microscopic-hematuria-reasonable-and-risk-adapted-diagnostic-evaluation
#3
REVIEW
N Löbig, F Wezel, T Martini, B Schröppel, C Bolenz
BACKGROUND: Microscopic hematuria that is not explained by an obvious underlying condition is a frequent and often an incidental finding that commonly triggers urological or nephrological evaluation. Potential underlying conditions range from benign to severe malignant diseases of the kidneys and urinary tract. MATERIALS AND METHODS: A nonsystematic literature search was performed, focusing on potential urological and nephrological causes of hematuria. National and international guidelines were considered and diagnostic as well as follow-up strategies are discussed...
June 22, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28538493/committee-opinion-no-703-summary-asymptomatic-microscopic-hematuria-in-women
#4
(no author information available yet)
Asymptomatic microscopic hematuria is an important clinical sign of urinary tract malignancy. Asymptomatic microscopic hematuria has been variably defined over the years. In addition, the evidence primarily is based on data from male patients. However, whether the patient is a man or a woman influences the differential diagnosis of asymptomatic microscopic hematuria, and the risk of urinary tract malignancy (bladder, ureter, and kidney) is significantly less in women than in men. Among women, being older than 60 years, having a history of smoking, and having gross hematuria are the strongest predictors of urologic cancer...
June 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28418525/asymptomatic-microscopic-hematuria-rethinking-the-diagnostic-algorithm
#5
Leslee L Subak, Deborah Grady
No abstract text is available yet for this article.
June 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28418451/cost-effectiveness-of-common-diagnostic-approaches-for-evaluation-of-asymptomatic-microscopic-hematuria
#6
Joshua A Halpern, Bilal Chughtai, Hassan Ghomrawi
Importance: Asymptomatic microscopic hematuria (AMH) is highly prevalent and may signal occult genitourinary (GU) malignant abnormality. Common diagnostic approaches differ in their costs and effectiveness in detecting cancer. Given the low prevalence of GU malignant abnormality among patients with AMH, it is important to quantify the cost implications of detecting cancer for each approach. Objective: To estimate the effectiveness, costs, and incremental cost per cancer detected (ICCD) for 4 common diagnostic approaches evaluating AMH...
June 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28399927/bk-viruria-and-viremia-in-children-with-systemic-lupus-erythematosus
#7
Nirupama Gupta, Cuong Q Nguyen, Renee F Modica, Melissa E Elder, Eduardo H Garin
BACKGROUND: BK virus (BKV) is a ubiquitous polyoma virus that lies dormant in the genitourinary tract once acquired in early childhood. In states of cellular immunodeficiency, the virus can reactivate to cause hemorrhagic cystitis and nephritis. Children with systemic lupus erythematosus (SLE) have an increased risk of developing infectious complications secondary to their immunocompromised state from the administration of several immuno-modulatory drugs. Currently, there are no data regarding the prevalence of BK viruria or viremia in children with SLE...
April 11, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28368896/committee-opinion-no-703-asymptomatic-microscopic-hematuria-in-women
#8
(no author information available yet)
Asymptomatic microscopic hematuria is an important clinical sign of urinary tract malignancy. Asymptomatic microscopic hematuria has been variably defined over the years. In addition, the evidence primarily is based on data from male patients. However, whether the patient is a man or a woman influences the differential diagnosis of asymptomatic microscopic hematuria, and the risk of urinary tract malignancy (bladder, ureter, and kidney) is significantly less in women than in men. Among women, being older than 60 years, having a history of smoking, and having gross hematuria are the strongest predictors of urologic cancer...
June 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28210641/atypical-plasmacytic-proliferation-in-a-case-of-c3-glomerulopathy-pathophysiology-demystified
#9
Osama Elfituri, Nathan Aardsma, Suman Setty, Frederick Behm, Kimberly Czech
An 11-year-old Hispanic female underwent evaluation of asymptomatic proteinuria and hematuria. The patient denied fever, edema, and gross hematuria. Urinalysis showed mild proteinuria, and a urine microscopic examination revealed red blood cells. Screening tests for glomerulonephritis revealed a low C3 and negative ANA, ASO, DNAse-B, and ANCA. Histological examination of a renal biopsy specimen showed glomeruli with endocapillary proliferation, a predominant C3 deposition in the capillary loops by immunofluorescence, and electron dense deposits in the mesangium, paramesangium, and capillary walls by electron microscopy consistent with a diagnosis of C3 glomerulopathy...
January 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28188755/defining-the-prevalence-of-asymptomatic-microscopic-hematuria-among-women-with-symptomatic-pelvic-organ-prolapse-implications-for-recommending-subsequent-diagnostic-evaluation
#10
Brian J Linder, Stephen A Boorjian, Emanuel C Trabuco, John B Gebhart, John A Occhino
OBJECTIVE: To evaluate the prevalence of asymptomatic microscopic hematuria (AMH) in women presenting with POP, as well as the relationship of POP stage with AMH. MATERIALS AND METHODS: Charts of women evaluated in a Female Pelvic Medicine and Reconstructive Surgery clinic between January 2015 and July 2016 were retrospectively reviewed. The prevalence of AMH (≥3 red blood cells per high-powered field on 1 urinalysis) was compared for women with symptomatic POP and those with urinary incontinence (UI) without symptomatic POP...
May 2017: Urology
https://www.readbyqxmd.com/read/28116915/non-visible-asymptomatic-haematuria-a-review-of-the-guidelines-from-the-urologist-s-perspective
#11
REVIEW
Petros Sountoulides, Ioannis Mykoniatis, Linda Metaxa
Non-visible hematuria, also referred to as 'microscopic hematuria' or 'dipstick positive hematuria' is a common reason for urology referrals with prevalence rates that range from 13% to 20%. The main concern for investigating non-visible hematuria, especially in the absence of lower urinary tract symptoms, is its potential relation to urinary tract malignancy, which however does not exceed 5%. The pathway of investigation of non-visible hematuria is impeded by the lack of clarity over definitions, diagnosis and specialist referral criteria...
March 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28081313/clinical-and-histopathological-features-of-asymptomaticpersistent-microscopic-hematuria-in-children
#12
Serçin Güven, İbrahim Gökçe, Neslihan Çiçek Deniz, Ülger Altuntaş, Nurdan Yıldız, Harika Alpay
BACKGROUND/AIM: We analyzed the clinical and pathological features and prognosis of 106 children with persistent asymptomatic microscopic hematuria (PAMH) with or without mild proteinuria. MATERIALS AND METHODS: This was a retrospective study of 106 children who were referred to our clinics from 2000 to 2013 for evaluation of PAMH. RESULTS: Among the 106 patients, 69 (65%) were female and 37 (35%) were male. The patients were divided into two groups: 101 patients with isolated microscopic hematuria (IMH) and 5 patients with asymptomatic microscopic hematuria and mild proteinuria (AMHP)...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28060986/-ultrastructural-alterations-in-renal-biopsy-leading-to-the-diagnosis-of-hiv-infection
#13
Jorge Vega, M Elizabeth Barthel, Gonzalo P Méndez
HIV infection has different clinical presentations. We report a 21-year-old male with longstanding isolated microscopic hematuria attributed to thin glomerular basement membrane disease, who after 15 years of follow-up presented with significant proteinuria. A kidney biopsy was performed, revealing the presence of tubulo-reticular inclusions in the glomerular endothelial cells. This finding led to suspect an HIV infection, which was verified. Antiretroviral therapy, angiotensin-converting enzyme and angiotensin II receptor blockers were prescribed...
September 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/27617212/spontaneous-ureteral-urine-extravasation-from-invasion-of-a-high-grade-angiosarcoma
#14
Matthew Truong, Wenqing Cao, Erdal Erturk
A 69 year-old male with a past medical history of hypertension, diabetes, and atrial fibrillation presented to the Urology clinic with asymptomatic microscopic hematuria. His work up for hematuria included a negative cystoscopy and a computed tomography (CT) scan, which revealed what appeared to be a fluid collection around the left kidney with a perinephric infiltrative mass and two para-aortic enlarged lymph nodes.
November 2016: Urology Case Reports
https://www.readbyqxmd.com/read/27461832/urinary-bladder-carcinoma-with-divergent-differentiation-featuring-small-cell-carcinoma-sarcomatoid-carcinoma-and-liposarcomatous-component
#15
Mariko Yasui, Teppei Morikawa, Tohru Nakagawa, Jimpei Miyakawa, Daichi Maeda, Yukio Homma, Masashi Fukayama
Both small cell carcinoma and sarcomatoid carcinoma of the urinary bladder are highly aggressive tumors, and a concurrence of these tumors is extremely rare. We report a case of urinary bladder cancer with small cell carcinoma as a predominant component, accompanied by sarcomatoid carcinoma and conventional urothelial carcinoma (UC). Although the small cell carcinoma component had resolved on receiving chemoradiotherapy, rapid growth of the residual tumor led to a fatal outcome. A 47-year-old man presented with occasional bladder irritation and had a 2-year history of asymptomatic hematuria...
September 2016: Pathology, Research and Practice
https://www.readbyqxmd.com/read/27318261/assessing-the-costs-of-extraurinary-findings-of-computed-tomography-urogram-in-the-evaluation-of-asymptomatic-microscopic-hematuria
#16
Win Shun Lai, James Ellenburg, Mark E Lockhart, Peter N Kolettis
OBJECTIVE: To assess the costs associated with incidental extraurinary findings on computed tomography urogram (CTU) in patients with asymptomatic microscopic hematuria. MATERIALS AND METHODS: A retrospective review was performed to identify all CTUs performed for asymptomatic microscopic hematuria at our institution from 2012 to 2014. All genitourinary (GU) and incidental extraurinary findings were documented. Further clinical follow-up to May 2015 was reviewed to determine if any referrals, tests, imaging, and/or procedures were ordered based on the initial CTU...
September 2016: Urology
https://www.readbyqxmd.com/read/27247500/the-natural-course-of-biopsy-proven-isolated-microscopic-hematuria-a-single-center-experience-of-350-patients
#17
Hae Min Lee, Ji In Hyun, Ji-Won Min, Kyungsoo Lee, Yong Kyun Kim, Euy Jin Choi, Ho Cheol Song
The increasing interest in healthcare and health screening events is revealing additional cases of asymptomatic isolated microscopic hematuria (IMH). However, a consensus of the evaluation and explanation of the IMH prognosis is controversial among physicians. Here, we present the natural course of IMH together with the pathological diagnosis and features to provide supportive data when approaching patients with IMH. We retrospectively evaluated 350 patients with IMH who underwent a renal biopsy between 2002 and 2011, and the pathological diagnosis and chronic histopathological features (glomerulosclerosis, interstitial fibrosis, and tubular atrophy) were reviewed...
June 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/26842624/igm-nephropathy-is-it-closer-to-minimal-change-disease-or-to-focal-segmental-glomerulosclerosis
#18
REVIEW
R Brugnano, R Del Sordo, C Covarelli, E Gnappi, S Pasquali
Immunoglobulin (Ig)M nephropathy (IgMN), known since 1978, is a very controversial clinicopathological entity characterized by IgM diffuse deposits in the mesangium at immunofluorescence whereas light microscop identifies minimal glomerular lesion, hypercellularity and expansion of the mesangium or sclerotic focal, segmental lesion. Clinically, it is a nephrotic syndrome, especially in pediatric patients, or asymptomatic proteinuria and/or isolated hematuria. These characteristics narrowly define IgMN between minimal change disease and focal segmental glomerulosclerosis, so it is not often recognized as a separate pathology...
August 2016: Journal of Nephrology
https://www.readbyqxmd.com/read/26810935/hematuria-as-a-marker-of-occult-urinary-tract-cancer-advice-for-high-value-care-from-the-american-college-of-physicians
#19
Matthew Nielsen, Amir Qaseem
BACKGROUND: The presence of blood in the urine, or hematuria, is a common finding in clinical practice and can sometimes be a sign of occult cancer. This article describes the clinical epidemiology of hematuria and the current state of practice and science in this context and provides suggestions for clinicians evaluating patients with hematuria. METHODS: A narrative review of available clinical guidelines and other relevant studies on the evaluation of hematuria was conducted, with particular emphasis on considerations for urologic referral...
April 5, 2016: Annals of Internal Medicine
https://www.readbyqxmd.com/read/26809805/identification-of-47-novel-mutations-in-patients-with-alport-syndrome-and-thin-basement-membrane-nephropathy
#20
Stefanie Weber, Katja Strasser, Sabine Rath, Achim Kittke, Sonja Beicht, Martin Alberer, Bärbel Lange-Sperandio, Peter F Hoyer, Marcus R Benz, Sabine Ponsel, Lutz T Weber, Hanns-Georg Klein, Julia Hoefele
BACKGROUND: Alport syndrome (ATS) is a progressive hereditary nephropathy characterized by hematuria and proteinuria. It can be associated with extrarenal manifestations. In contrast, thin basement membrane nephropathy (TBMN) is characterized by microscopic hematuria, is largely asymptomatic, and is rarely associated with proteinuria and end-stage renal disease. Mutations have been identified in the COL4A5 gene in ATS and in the COL4A3 and COL4A4 genes in ATS and TBMN. To date, more than 1000 different mutations in COL4A5, COL4A3, and COL4A4 are known...
June 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
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