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Instrumental learning

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https://www.readbyqxmd.com/read/28634887/aberrant-connections-between-climbing-fibres-and-purkinje-cells-induce-alterations-in-the-timing-of-an-instrumental-response-in-the-rat
#1
Lorena Gaytán-Tocavén, Miguel Ángel López-Vázquez, Miguel Ángel Guevara, María Esther Olvera-Cortés
Cerebellar participation in timing and sensory-motor sequences has been supported by several experimental and clinical studies. A relevant role of the cerebellum in timing of conditioned responses in the range of milliseconds has been demonstrated, but less is known regarding the role of the cerebellum in supra-second timing of operant responses. A dissociated role of the cerebellum and striatum in timing in the millisecond and second range had been reported, respectively. The climbing fibre-Purkinje cell synapse is crucial in timing models; thus, the aberrant connection between these cellular elements is a suitable model for evaluating the contribution of the cerebellum in timing in the supra-second range...
June 20, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28632009/self-observation-and-peer-feedback-as-a-faculty-development-approach-for-problem-based-learning-tutors-a-program-evaluation
#2
Irène Garcia, Richard W James, Paul Bischof, Anne Baroffio
PROBLEM: Good teaching requires spontaneous, immediate, and appropriate action in response to various situations. It is even more crucial in problem-based learning (PBL) tutorials, as the tutors, while directing students toward the identification and attainment of learning objectives, must stimulate them to contribute to the process and provide them with constructive feedback. PBL tutors in medicine lack opportunities to receive feedback from their peers on their teaching strategies. Moreover, as tutorials provide little or no time to stop and think, more could be learned by reflecting on the experience than from the experience itself...
March 2, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28630509/peer-evaluation-instrument-development-administration-and-assessment-in-a-team-based-learning-curriculum
#3
Matthew G Fete, Robert C Haight, Peter Clapp, Marianne McCollum
Objective. To design and implement an instrument capable of providing students with valuable peer feedback on team behaviors and to provide results of the administration of the instrument. Methods. A three-part instrument was designed that requires teammate rankings with justification on attributes aligned with school outcomes and team functioning, reporting of student behaviors, and provision of feedback on the value of peer contributions to their team. Score results after three years of administration were analyzed...
May 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28627906/evidence-of-a-goal-directed-process-in-human-pavlovian-instrumental-transfer
#4
Tina Seabrooke, Mike E Le Pelley, Lee Hogarth, Chris J Mitchell
Cues that signal rewards can motivate reward-seeking behaviors, even for outcomes that are not currently desired. Three experiments examined this phenomenon, using an outcome-selective Pavlovian-instrumental transfer (PIT) design and an outcome devaluation procedure. In Experiment 1, participants learned to perform one response to earn crisps points and another response to earn popcorn points. One outcome was then devalued by adulterating it to make it taste unpleasant. On test, overall response choice was biased toward the outcome that had not been devalued, indicating goal-directed control...
June 19, 2017: Journal of Experimental Psychology. Animal Learning and Cognition
https://www.readbyqxmd.com/read/28623151/cognitive-performance-across-3-frailty-phenotypes-toledo-study-for-healthy-aging
#5
Cristina Rosado-Artalejo, Jose Antonio Carnicero, Jose Losa-Reyna, Amelia Guadalupe-Grau, Carmen Castillo-Gallego, Gonzalo Gutierrez-Avila, Ana Alfaro-Acha, Fernando Rodríguez-Artalejo, Leocadio Rodríguez-Mañas, Francisco José García-García
INTRODUCTION: Frailty is a strong predictor of adverse health events, but its impact on cognitive function is poorly understood. AIM: To assess cognitive performance in frailty and to identify the frailty stage where cognitive impairment begins. METHODS: Data were taken from 2044 people aged ≥65 years without cognitive impairment selected from the Toledo Study for Healthy Aging, a population-based cohort of older adults. Frailty status was assessed by 3 different scales: Frailty Phenotype (FP), Frailty Trait Scale (FTS), and Frailty Index (FI)...
June 13, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28619413/visiting-trainees-in-global-settings-host-and-partner-perspectives-on-desirable-competencies
#6
William Cherniak, Emily Latham, Barbara Astle, Geoffrey Anguyo, Tessa Beaunoir, Joel Buenaventura, Matthew DeCamp, Karla Diaz, Quentin Eichbaum, Marius Hedimbi, Cat Myser, Charles Nwobu, Katherine Standish, Jessica Evert
BACKGROUND: Current competencies in global health education largely reflect perspectives from high-income countries (HICs). Consequently, there has been underrepresentation of the voices and perspectives of partners in low- and middle-income countries (LMICs) who supervise and mentor trainees engaged in short-term experiences in global health (STEGH). OBJECTIVE: The objective of this study was to better understand the competencies and learning objectives that are considered a priority from the perspective of partners in LMICs...
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28616601/minimally-invasive-surgery-for-gastric-cancer-in-brazil-current-status-and-perspectives-a-report-from-the-brazilian-laparoscopic-oncologic-gastrectomy-group-blogg
#7
REVIEW
Paulo Kassab, Wilson Luiz da Costa, Carlos Eduardo Jacob, Roberto de Moraes Cordts, Osvaldo Antônio Prado Castro, Leandro Cardoso Barchi, Ivan Cecconello, Amir Zeide Charruf, Felipe José Fernández Coimbra, Antônio Moris Cury, Alessandro Landskron Diniz, Igor Correia de Farias, Wilson Rodrigues de Freitas, André Luis de Godoy, Elias Jirjoss Ilias, Carlos Alberto Malheiros, Marcus Fernando Kodama Pertille Ramos, Heber Salvador de Castro Ribeiro, André Roncon Dias, Fábio Rodrigues Thuler, Osmar Kenji Yagi, Laércio Gomes Lourenço, Bruno Zilberstein
The minimally invasive surgery for gastric cancer in Brazil has begun about two years after the first laparoscopic gastrectomy (LG) performed by Kitano in Japan, in 1991. Although the report of first surgeries shows the year of 1993, there was no dissemination of the technique until the years 2010. At that time with the improvement of optical devices, laparoscopic instruments and with the publications coming from Asia, several Brazilian surgeons felt encouraged to go to Korea and Japan to learn the standardization of the LG...
2017: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28615272/what-do-adolescents-with-asthma-really-think-about-adherence-to-inhalers-insights-from-a-qualitative-analysis-of-a-uk-online-forum
#8
Anna De Simoni, Robert Horne, Louise Fleming, Andrew Bush, Chris Griffiths
OBJECTIVE: To explore the barriers and facilitators to inhaled asthma treatment in adolescents with asthma. DESIGN: Qualitative analysis of posts about inhaler treatment in adolescents from an online forum for people with asthma. Analysis informed by the Perceptions and Practicalities Approach. PARTICIPANTS: Fifty-four forum participants (39 adolescents ≥16 years, 5 parents of adolescents, 10 adults with asthma) identified using search terms 'teenager inhaler' and 'adolescent inhaler'...
June 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28612645/associative-mechanisms-involved-in-specific-pavlovian-to-instrumental-transfer-pit-in-human-learning-tasks
#9
Daniel E Alarcón, Charlotte Bonardi, Andrew R Delamater
Four experiments compared the effect of forward and backward conditioning procedures on the ability of conditioned stimuli (CSs) to elevate instrumental responding in a Pavlovian-to-instrumental transfer (PIT) task. Two responses were each trained with one distinct outcome (R1->O1, R2->O2), either concurrently (Experiment 1) or separately (Experiments 2, 3 and 4). Then, in Experiments 1 and 2, four CSs were either followed or preceded by one outcome (A-->O1, B->O2,O1->C, O2->D). In Experiment 3 each CS was preceded and followed by an outcome: for one group of participants both outcomes were identical (e...
June 14, 2017: Quarterly Journal of Experimental Psychology: QJEP
https://www.readbyqxmd.com/read/28605481/measurement-properties-of-short-lower-extremity-functional-exercise-tests-in-people-with-chronic-obstructive-pulmonary-disease-systematic-review
#10
Kylie N Johnston, Adrian J Potter, Anna Phillips
Background: An increasing variety of short functional exercise tests are reported in people with chronic obstructive pulmonary disease (COPD). Systematic review of the psychometric properties of these exercise tests is indicated. Purpose: The aim of this study was to determine the reliability, validity and responsiveness of short (less than 6 minutes duration) lower extremity functional exercise tests in people with COPD. Data Sources: Five databases were searched: MEDLINE, EmBASE, Scopus, AMED and CINAHL...
June 12, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28599588/teaching-parents-about-responsive-feeding-through-a-vicarious-learning-video-a-pilot-randomized-controlled-trial
#11
Tracey Ledoux, Jessica Robinson, Tom Baranowski, Daniel P O'Connor
The American Academy of Pediatrics and World Health Organization recommend responsive feeding (RF) to promote healthy eating behaviors in early childhood. This project developed and tested a vicarious learning video to teach parents RF practices. A RF vicarious learning video was developed using community-based participatory research methods. Fifty parents of preschoolers were randomly assigned to watch Happier Meals or a control video about education. Knowledge and beliefs about RF practices were measured 1 week before and immediately after intervention...
June 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28598917/improving-performance-by-monitoring-the-success-rate-of-peripheral-nerve-blocks
#12
Sietske M K Bakker, Rudolf Stienstra
In our hospital, we introduced a system to measure the collective and individual efficacy of brachial plexus and popliteal nerve blocks with the objective to create transparency as an instrument for monitoring and improvement. Initially, individual results were anonymous, but after 1 year anonymity was lifted within the team of anesthesiologists and results are now discussed quarterly. Collective performance of interscalene, supraclavicular, and popliteal blocks improved significantly over time. Sharing and discussing collective and individual performance has resulted in critical self-appraisal and increased willingness to learn from each other and strengthened the team's ambition for further improvement...
June 8, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28598713/robot-assisted-endoscope-guidance-versus-manual-endoscope-guidance-in-functional-endonasal-sinus-surgery-fess
#13
Klaus Wolfgang Eichhorn, Ralf Westphal, Markus Rilk, Carsten Last, Friedrich Bootz, Friedrich Wahl, Mark Jakob, Thorsten Send
BACKGROUND: Having one hand occupied with the endoscope is the major disadvantage for the surgeon when it comes to functional endoscopic sinus surgery (FESS). Only the other hand is free to use the surgical instruments. Tiredness or frequent instrument changes can thus lead to shaky endoscopic images. METHODS: We collected the pose data (position and orientation) of the rigid 0° endoscope and all the instruments used in 16 FESS procedures with manual endoscope guidance as well as robot-assisted endoscope guidance...
June 9, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28596214/changes-in-mechanical-work-during-neural-adaptation-to-asymmetric-locomotion
#14
Brian P Selgrade, Montakan Thajchayapong, Gloria E Lee, Megan E Toney, Young-Hui Chang
Minimizing whole body metabolic cost has been suggested to drive the neural processes of locomotor adaptation. Mechanical work performed by the legs should dictate the major changes in whole body metabolic cost of walking while providing greater insight into temporal and spatial mechanisms of adaptation. We hypothesized changes in mechanical work by the legs during an asymmetric split-belt walking adaptation task could explain previously observed changes in whole body metabolic cost. We predicted subjects would immediately increase mechanical work performed by the legs when first exposed to split-belt walking, followed by a gradual decrease throughout adaptation...
June 8, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28594324/mecp2-regulates-tet1-catalyzed-demethylation-ctcf-binding-and-learning-dependent-alternative-splicing-of-the-bdnf-gene-in-turtle
#15
Zhaoqing Zheng, Ganesh Ambigapathy, Joyce Keifer
MECP2 mutations underlying Rett syndrome cause widespread misregulation of gene expression. Functions for MeCP2 other than transcriptional are not well understood. In an ex vivo brain preparation from the pond turtle Trachemys scripta elegans, an intraexonic splicing event in the brain-derived neurotrophic factor (BDNF) gene generates a truncated mRNA transcript in naïve brain that is suppressed upon classical conditioning. MeCP2 and its partners, splicing factor Y-box binding protein 1 (YB-1) and methylcytosine dioxygenase 1 (Tet1), bind to BDNF chromatin in naïve but dissociate during conditioning; the dissociation correlating with decreased DNA methylation...
June 8, 2017: ELife
https://www.readbyqxmd.com/read/28592154/-i-just-had-to-be-flexible-and-show-good-patience-management-of-interactional-approaches-to-enact-mentoring-roles-by-peer-mentors-with-developmental-disabilities
#16
Ariel E Schwartz, Jessica M Kramer
PURPOSE: Peer mentoring may be an effective approach for fostering skill development for mentors and mentees with developmental disabilities. However, little is known about how mentors with developmental disabilities perceive and enact their roles. RESEARCH QUESTIONS: (1) How do young adults with developmental disabilities describe their role as a peer mentor in the context of instrumental peer mentoring? (2) How do they enact their perceived roles? METHODS: Thematic analysis of semi-structured reflections completed by six mentors with developmental disabilities (ages 17-35) with multiple mentoring experiences...
June 8, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28584865/the-gender-lens-development-of-a-learning-aid-to-introduce-gender-medicine
#17
Simone Weyers, Anja Vervoorts, Nico Dragano, Miriam Engels
Background and aim: Gender medicine takes into account biological and social differences between men and women in terms of prevalence and course of disease, diagnosis and therapy. Medical students should be made aware of this in the early stages of medical education. However, there is hardly any teaching material currently available. This article presents the adaption and first use of the German "Gender Lens," a tool to introduce gender medicine to medical students. Method: The original Canadian "Gender Lens Tool" was translated into German, tested by (n=5) teachers and adapted based on current scientific concepts...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/28583196/effects-of-unilateral-real-time-biofeedback-on-propulsive-forces-during-gait
#18
Christopher Schenck, Trisha M Kesar
BACKGROUND: In individuals with post-stroke hemiparesis, reduced push-off force generation in the paretic leg negatively impacts walking function. Gait training interventions that increase paretic push-off can improve walking function in individuals with neurologic impairment. During normal locomotion, push-off forces are modulated with variations in gait speed and slope. However, it is unknown whether able-bodied individuals can selectively modulate push-off forces from one leg in response to biofeedback...
June 6, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28581350/determining-the-key-drivers-and-mitigating-factors-that-influence-the-role-of-the-nurse-and-or-midwife-consultant-a-cross-sectional-survey
#19
Ritin S Fernandez, Suzanne Sheppard-Law, Vicki Manning
BACKGROUND: Globally, many nurses and midwives are working at an advanced practice level. The role of a Nurse and/or Midwife Consultant encompasses a diverse and complex interaction between five specified domains namely Clinical Service and Consultancy, Clinical Leadership, Research, Education, and Clinical Services Planning and Management. OBJECTIVE: The objective of this replication study was to identify the key drivers and mitigating factors that impact the role of Australian Nurse and/or Midwife Consultants...
June 21, 2017: Contemporary Nurse
https://www.readbyqxmd.com/read/28579691/does-prediction-error-drive-one-shot-declarative-learning
#20
Andrea Greve, Elisa Cooper, Alexander Kaula, Michael C Anderson, Richard Henson
The role of prediction error (PE) in driving learning is well-established in fields such as classical and instrumental conditioning, reward learning and procedural memory; however, its role in human one-shot declarative encoding is less clear. According to one recent hypothesis, PE reflects the divergence between two probability distributions: one reflecting the prior probability (from previous experiences) and the other reflecting the sensory evidence (from the current experience). Assuming unimodal probability distributions, PE can be manipulated in three ways: (1) the distance between the mode of the prior and evidence, (2) the precision of the prior, and (3) the precision of the evidence...
June 2017: Journal of Memory and Language
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