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Radical hysterectomy

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https://www.readbyqxmd.com/read/28439968/effects-of-an-ep2-and-ep3-receptor-dual-agonist-ono-8055-on-a-radical-hysterectomy-induced-underactive-bladder-model-in-monkeys
#1
Hidekazu Matsuya, Noritoshi Sekido, Jun Kida, Hiroko Mashimo, Daisuke Wakamatsu, Hiroki Okada
OBJECTIVES: The objective was to develop an underactive bladder (UAB) model in primates and to evaluate the potential of prostanoid EP2 and EP3 receptor dual agonist ONO-8055 to become a therapeutic agent for UAB. METHODS: A surgical procedure resembling radical hysterectomy was performed on female cynomolgus monkeys. Subsequently, in vitro muscle strip studies were performed using bladder muscle strips from normal monkeys and monkeys that underwent surgery. In addition, uroflowmetric data were obtained at specified days after the surgery...
April 25, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28429948/-robotic-surgery-in-gynecology
#2
R Pilka
INTRODUCTION: The aim of this review is to provide a general historical and contemporary perspective on the implementation and use of robot-assisted laparoscopy in gynecology as well as the experience gained to date. CONTENTS: Robotic-assisted laparoscopic surgeries in gynecology include benign hysterectomy, myomectomy, radical hysterectomy, lymph node dissections or sacrocolpopexies. Robot-assisted gynecologic surgery is often associated with longer operating room time but generally similar clinical outcomes, decreased blood loss and shorter hospital stay when compared to open or laparoscopic surgery...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28424084/durable-complete-remission-with-aromatase-inhibitor-therapy-in-a-patient-with-metastatic-uterine-carcinosarcoma-with-poor-performance-status-and-coagulation-disorders-a-case-report
#3
P Martin-Romano, M Jurado, M A Idoate, L Arbea, J L Hernandez-Lizoain, D Cano, J A Paramo, S Martin-Algarra
BACKGROUND: Chemotherapy is considered the most appropriate treatment for metastatic uterine sarcoma, despite its limited efficacy. No other treatment has been conclusively proved to be a real alternative, but some reports suggest that anti-hormonal therapy could be active in a small subset of patients. We report the case of a patient with metastatic uterine carcinosarcoma with positive hormonal receptors and a complete pathological response. CASE PRESENTATION: A 54-year-old white woman presented to our emergency room with hypovolemic shock and serious vaginal bleeding...
April 19, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28423687/predictive-factors-of-para-aortic-lymph-nodes-metastasis-in-cervical-cancer-patients-a-retrospective-analysis-based-on-723-para-aortic-lymphadenectomy-cases
#4
Xiaotian Han, Hao Wen, Xingzhu Ju, Xiaojun Chen, Guihao Ke, Yuqi Zhou, Jin Li, Lingfang Xia, Jia Tang, Shanhui Liang, Xiaohua Wu
Para-aortic lymph node (PALN) dissection is optional and controversial in patients with stage IB1-IIA2 cervical cancer. This retrospective study investigated PALN involvement patterns and evaluated preoperative clinical factors. A total of 723 consecutive FIGO stage IB1-IIA2 cervical cancer patients were included in the study. All patients underwent radical hysterectomy/radical trachelectomy, pelvic lymph node dissection, and PALN dissection. PALN metastasis was found in 101 (14.0%) patients, and the positive PALN rates of stage IB1, IB2, IIA1, and IIA2 were 8...
March 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423382/late-recurrence-of-early-stage-cervical-cancer-more-than-3-years-after-radical-hysterectomy-with-pelvic-node-dissection
#5
Jitti Hanprasertpong, Ingporn Jiamset
No abstract text is available yet for this article.
April 20, 2017: Oncology Research and Treatment
https://www.readbyqxmd.com/read/28399030/challenging-salpingectomy-as-a-risk-reducing-measure-for-ovarian-cancer-histopathological-analysis-of-the-tubo-ovarian-interface-in-women-undergoing-risk-reducing-salpingo-oophorectomy
#6
Chloe Ayres, Gayanie Ratnayake, Orla McNally, Michael Quinn
OBJECTIVE: Opportunistic bilateral salpingectomy is now promoted for women at the time of hysterectomy for a benign disease, consequent to the fimbrial end of the fallopian tube emerging as the primary site for carcinogenesis in high-grade serous carcinomas. In high-risk women with an identified germ line mutation, bilateral salpingo-oophorectomy offers the greatest risk reduction for ovarian cancer. Currently, no prospective evidence exists with respect to the effectiveness of opportunistic salpingectomy alone in preventing ovarian cancer...
May 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28394551/mesonephric-adenocarcinoma-of-endocervix-with-lobular-mesonephric-hyperplasia-case-report
#7
Mario Puljiz, Damir Danolić, Lucija Kostić, Ilija Alvir, Darko Tomica, Ivica Mamić, Ivana Vlastelica Munivrana, Marko Puljiz, Danko Velimir Vrdoljak, Melita Perić Balja
Mesonephric adenocarcinoma is a rare variant of cervical adenocarcinoma. We present a case of mesonephric adenocarcinoma of endocervix with cervical and vaginal lobular mesonephric hyperplasia in a 57-year-old woman. Vaginal bleeding persisting for 12 months was the only symptom. Histopathologic findings and characteristic immunophenotype are crucial for the diagnosis. The tumor was composed of papillary formation with a central fi brovascular stroma, villoglandular and densely compact tubular structures containing intraluminal eosinophilic secretion, and coated with one or more rows of cylindrical atypical epithelial cells...
June 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/28392128/is-parametrectomy-always-necessary-in-early-stage-cervical-cancer
#8
Glauco Baiocchi, Louise de Brot, Carlos Chaves Faloppa, Henrique Mantoan, Matheus Rodrigues Duque, Levon Badiglian-Filho, Alexandre Andre Balieiro Anastacio da Costa, Lillian Yuri Kumagai
OBJECTIVE: Increasing data suggest that patients with early-stage cervical cancer and favorable pathological characteristics have a low risk of parametrial invasion (PI) and benefit from less radical surgery. Our aim was to evaluate the clinical-pathological factors that are related to PI and identify a group of patients who are at low risk for PI. METHODS: We analyzed a series of 345 patients with stage Ia2 to Ib2 cervical cancer, for which they underwent radical surgery from January 1990 to October 2016 at AC Camargo Cancer Center...
April 6, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28384936/transvaginal-sonography-versus-cystoscopy-for-detecting-urinary-bladder-invasion-in-early-stage-cervical-cancer
#9
Vijay Zutshi, Binni Makkar, Anju Garg, Swaraj Batra
INTRODUCTION: Cervical cancer is a major cause of mortality from cancer among women. In it's early stage pre operative staging with cystoscopy is a standard procedure for the detection of urinary bladder involvement. AIM: The present study was conducted with the aim to compare the efficacy of Transvaginal Sonography (TVS) and cystoscopy in diagnosing bladder involvement in early stage cervical cancer patients by confirming it intraoperatively and further by histopathologic examination...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28382145/class-i-versus-class-iii-radical-hysterectomy-in-stage-ib1-tumor-%C3%A2-2-cm-cervical-cancer-a-matched-cohort-study
#10
Wei Wang, Chun-Liang Shang, Qi-Qiao Du, Di Wu, Yan-Chun Liang, Tian-Yu Liu, Jia-Ming Huang, Shu-Zhong Yao
Background & Aims: The long-term oncological outcome of Class I hysterectomy to treat stage IB1 cervical cancer is unclear. The aim of the present study was to compare the surgical and long-term oncological outcomes of Class I hysterectomy and Class III radical hysterectomy for treatment of stage IB1 cervical cancer (tumor ≤ 2 cm). Methods: Seventy stage IB1 cervical cancer patients (tumor ≤ 2 cm) underwent Class I hysterectomy and 577 stage IB1 cervical cancer patients (tumor ≤ 2 cm) underwent Class III radical hysterectomy were matched with known risk factors for recurrence by greedy algorithm...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28355765/-liposuction-combined-with-lymphatico-venous-anastomosis-for-treatment-of-secondary-lymphedema-of-the-lower-limbs-a-report-of-49-cases
#11
K Chang, S Xia, Y G Sun, J F Xin, W B Shen
Objective: To study the clinical effects of liposuction combined with lymphatico-venous anastomosis for treatment of secondary lymphedema of the lower limbs. Methods: A retrospective analysis was performed for 49 patients who had undergone liposuction combined with lymphatico-venous anastomosis to treat secondary lymphedema of the lower limbs at Department of Lymph Surgery, Beijing Shijitan Hospital from November 2013 to February 2015.All patients were female aging from 31 to 70 years with median age of (52±10)years...
April 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28345784/quality-of-life-in-cervical-cancer-survivors-and-healthy-women-thai-urban-population-study
#12
Pichita Prasongvej, Tongta Nanthakomon, Kankamol Jaisin, Athita Chanthasenanont, Supapen Lertvutivivat, Chamnan Tanprasertkul, Kornkarn Bhamarapravatana, Komsun Suwannarurk
Background : To determine a baseline quality of life (QoL) in cervical cancer survivors compared to that of healthy subjects in the tertiary Thammasat University Hospital, Thailand. Materials and Methods: The investigation was conducted at the outpatient gynecological department of Thammasat University Hospital between January and June 2016. A total of 192 women were entered into the study (97 cervical cancer survivors; 37 after radical hysterectomy (RH), 43 with concurrent chemoradiation (CRT), and 17 featuring both RH and CRT; and 95 control subjects from the same outpatient department with no history of malignancy)...
February 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28344966/lower-limb-compartment-syndrome-by-reperfusion-injury-after-treatment-of-arterial-thrombosis-post-laparoscopic-radical-hysterectomy-and-pelvic-lymph-node-dissection-for-cervical-cancer
#13
Jihee Yeon, Ye Won Jung, Shin Seok Yang, Byung Hun Kang, Mina Lee, Young Bok Ko, Jung Bo Yang, Ki Hwan Lee, Heon Jong Yoo
Compartment syndrome is a clinical condition associated with decreased blood circulation that can lead to swelling of tissue in limited space. Several factors including lithotomy position, prolonged surgery, intermittent pneumatic compressor, and reperfusion after treatment of arterial thrombosis may contribute to compartment syndrome. However, compartment syndrome rarely occurs after gynecologic surgery. In this case, the patient was diagnosed as compartment syndrome due to reperfusion injury after treatment of arterial thrombosis, which occurred after laparoscopic radical hysterectomy and pelvic lymph node dissection for cervical cancer...
March 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28331901/isolated-port-site-recurrence-of-node-negative-clinical-stage-ib1-cervical-adenocarcinoma
#14
Uma Deshmukh, Molly McAdow, Jonathan Black, Pei Hui, Masoud Azodi
INTRODUCTION: Port site metastasis after laparoscopic surgery for cervical cancer is a rare phenomenon. METHODS: We present a case report of isolated port site recurrence 4 years following laparoscopic surgery in a patient with node-negative, clinical stage IB1 cervical adenocarcinoma. RESULTS: A 44 year-old woman presented with a necrotic cervical lesion. A biopsy of the mass revealed invasive endocervical adenocarcinoma. She underwent a robotic-assisted radical hysterectomy, bilateral salpingectomy, and pelvic lymph node dissection with bilateral oophoropexy...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28314289/dose-dense-paclitaxel-and-carboplatin-based-neoadjuvant-chemotherapy-followed-by-surgery-or-concurrent-chemo-radiotherapy-in-cervical-cancer-a-preliminary-analysis
#15
Angiolo Gadducci, Cecilia Barsotti, Concetta Laliscia, Stefania Cosio, Antonio Fanucchi, Roberta Tana, Maria Grazia Fabrini
AIM: To assess preliminary results with dose-dense neoadjuvant chemotherapy (NACT) prior to surgery or concurrent chemo-radiotherapy (CCRT) in cervical cancer. PATIENTS AND METHODS: Thirty patients received weekly paclitaxel (80 mg/m(2)) plus carboplatin (AUC2) for 6 cycles followed by radical hysterectomy in 16 (stage Ib2-IIb), conisation in one (stage Ib1), and CCRT in 13 (stage Ib2-IIb). Median follow-up of survivors was 12 months (range=3-22). RESULTS: Among the surgically treated patients, clinical overall response rate (RR) was 82...
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28300465/laparoscopic-radical-hysterectomy-in-early-stage-cervical-cancer-a-systematic-review-and-meta-analysis
#16
Yue Zhao, Bo Hang, Guang-Wu Xiong, Xiao-Wei Zhang
PURPOSE: To investigate the value of laparoscopic radical hysterectomy (LRH) in the treatment of early stage cervical cancer by comparing intraoperative and postoperative outcomes with abdominal radical hysterectomy (ARH). MATERIALS AND METHODS: We searched the Medline, Web of Knowledge, Cochrane Library, and Chinese National Knowledge Infrastructure, through February 2, 2016 with keywords of "laparoscopic OR laparoscopy" AND "radical hysterectomy OR early cervical cancer OR stage IB, stage IB1, stage IB2, stage IIA, stage IIA1, stage IIA2, stage IIA cervical cancer" to identify all relevant studies that compared LRH with ARH in treating early cervical cancer...
March 16, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28275694/clear-cell-adenocarcinoma-of-the-cervix-in-second-generation-young-women-who-are-without-maternal-exposure-to-diethylstilbestrol-a-case-report
#17
Tanitra Tantitamit, Suttha Hamontri, Likit Rangsiratanakul
Clear cell adenocarcinoma of the cervix (CCAC) is a rare type of gynecological cancer. The risk factors and pathogenesis have yet to be clearly determined. This is a case report of a 19-year-old woman, who was never exposed to DES from her mother, who had gone for an examination for vaginal bleeding. A polypoid mass measured at 3 cm presenting in her cervix was discovered. Histological diagnosis following cervical biopsy proved the tumor to be a clear cell carcinoma. The patient was then referred to our hospital...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28254677/robotic-radical-parametrectomy-with-upper-vaginectomy-and-pelvic-lymphadenectomy-in-patients-with-occult-cervical-carcinoma-after-extrafascial-hysterectomy
#18
Arthur-Quan Tran, Stephanie A Sullivan, Paola A Gehrig, John T Soper, John F Boggess, Kenneth H Kim
STUDY OBJECTIVE: To confirm the safety and feasibility outcomes of robotic radical parametrectomy and pelvic lymphadenectomy and compare the clinicopathological features of women requiring adjuvant treatment with the historical literature. DESIGN: Retrospective cohort study and review of literature (Canadian Task Force classification II-2). SETTING: Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill. PATIENTS: All patients who underwent robotic radical parametrectomy with upper vaginectomy (RRPV), and pelvic lymphadenectomy for occult cervical cancer discovered after an extrafascial hysterectomy at our institution between January 2007 and December 2015...
February 22, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28238025/anesthetic-management-of-abdominal-radical-trachelectomy-for-uterine-cervical-cancer-during-pregnancy
#19
Jun Terukina, Misako Takamatsu, Takayuki Enomoto, Hiroshi Baba
Abdominal radical trachelectomy has been identified as a surgical option for fertility preservation in cervical cancer patients, particularly in pregnant women who strongly desire to continue their pregnancy. Since this procedure requires operating in the uterus, the hardness of the uterus can affect the ease of surgery. Generally, sevoflurane is used for anesthesia in non-obstetric surgery for pregnant women because uterine relaxation is advantageous for uterine blood flow maintenance. However, the use of sevoflurane during radical trachelectomy has not been thoroughly evaluated...
February 25, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28217683/lymphoepithelioma-like-carcinoma-of-the-uterine-cervix
#20
Hyun Sil Yun, Sun Kyung Lee, Gun Yoon, Hwi Gon Kim, Dong Hyung Lee, Yong Jin Na, Ook Hwan Choi, Dong Hoon Shin, Yong Jung Song
Lymphoepithelioma-like carcinoma (LELC) of the uterine cervix is exceedingly uncommon. We herein report a rare case of cervical LELC. A 45-year-old woman was admitted to gynecology department with vaginal bleeding for one month. Liquid-based cytology revealed atypical endometrial cells, not otherwise specified on her cervix. On a hysteroscopy, an endocervical mass was identified and the pathologic result was consistent with poorly differentiated squamous cell carcinoma. Magnetic resonance imaging and positron emission tomography with 2-deoxy-2-[fluorine-18] fluoro-D-glucose integrated with computed tomography revealed a 3...
January 2017: Obstetrics & Gynecology Science
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